Inhibitory effect of azole antifungal agents on the glucuronidation of lorazepam using rabbit liver microsomes in vitro

Biological and Pharmaceutical Bulletin

Volumn 23, Issue 5, 2000, Pages 669-671

  Sawamura, Ryoko ^a   Sato, Hitoshi ^a   Kawakami, Junichi ^b   Iga, Tatsuji ^a  

^a UNIVERSITY OF TOKYO HOSPITAL   (Japan)

^b UNIVERSITY OF TOYAMA   (Japan)

Author keywords

Azole antifungal agent; Competitive inhibition; Drug interaction; Glucuronidation; Lorazepam; Rabbit liver microsome

Indexed keywords

FLUCONAZOLE; KETOCONAZOLE; LORAZEPAM; MICONAZOLE; PYRROLE DERIVATIVE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; COMPETITIVE INHIBITION; CONTROLLED STUDY; DRUG GLUCURONIDATION; DRUG METABOLISM; ENZYME KINETICS; LIVER MICROSOME; NONHUMAN; RABBIT;

EID: 0034071455     PISSN: 09186158     EISSN: None     Source Type: Journal    
DOI: 10.1248/bpb.23.669     Document Type: Article

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