The expression of androgen receptors in human neck and limb muscles: Effects of training and self-administration of androgenic-anabolic steroids

Histochemistry and Cell Biology

Volumn 113, Issue 1, 2000, Pages 25-29

  Kadi, Fawzi ^a,b,c   Bonnerud, Patrik ^a   Eriksson, Anders ^a   Thornell, Lars Eric ^a,c  

^a UMEÅ UNIVERSITY   (Sweden)

^b CNRS   (France)

^c NATIONAL INSTITUTE FOR WORKING LIFE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ANABOLIC AGENT; ANDROGEN; ANDROGEN RECEPTOR;

ADULT; ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; EXERCISE; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; MUSCLE BIOPSY; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRAPEZIUS MUSCLE; VASTUS LATERALIS MUSCLE;

EID: 0034070966     PISSN: 09486143     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004180050003     Document Type: Article

References (37)

1. Allen DL, Monke SR, Talmadge RJ, Roy RR, Edgerton VR (1995) Plasticity of myonuclear number in hypertrophied and atrophied mammalian skeletal muscle fibres. J Appl Physiol 78:1969-1976
2. Bricout V, Germain P, Serrurier B, Guezennec C (1994) Changes in testosterone muscle receptors: Effects of an androgen treatment on physically trained rats. Cell Mol Biol 40:291-294
3. Cabric M, James NT (1983) Morphometric analyses on the muscles of exercise trained and untrained dogs. Am J Anat 166:359-368
4. Cabric M, Appell HJ, Resic A (1987) Effects of electrical stimulation of different frequencies on the myonuclei and fibre size in human muscle. Int J Sports Med 8:323-326
5. Chaikovskii VS, Ivanova EI, Rogozkin VA (1985) Content and utilization of testosterone in the cardiac and skeletal muscles of male rats during physical exercise. Probl Endokrinol Mosk 31:78-82
6. Chang C, Kokontis J, Swift S, Liao ST (1990) Molecular cloning and structural analysis of complementary DNA of human and rat androgen receptors. Prog Clin Biol Res 322:53-63
7. Deschenes MR, Maresh CM, Armstrong LE, Covault J, Kraemer WJ, Crivello JF (1994) Endurance and resistance exercise induce muscle fibre type specific responses in androgen binding capacity. J Steroid Biochem Mol Biol 50:175-179
8. Dorlochter M, Astrow SH, Herrera AA (1994) Effects of testosterone on a sexually dimorphic frog muscle: Repeated in vivo observations and androgen receptor distribution. J Neurobiol 25:897-916
9. Doumit ME, Cook DR, Merkel RA (1996) Testosterone up-regulates androgen receptors and decreases differentiation of porcine myogenic satellite cells in vitro. Endocrinology. 137:1385-1394
10. Galavazi G, Szirmai JA (1971) Cytomorphometry of skeletal muscle: The influence of age and testosterone on the rat m. levator ani. Z Zellforsch Mikrosk Anat 121:507-530
11. Goldberg AL, Etlinger JD, Goldspink DF, Jablecki C (1975) Mechanism of work-induced hypertrophy of skeletal muscle. Med Sci Sports Exerc 7:185-198
12. Hickson RC, Kurowski TG (1986) Anabolic steroids and training. Clin Sports Med 5:461-469
13. Hyyppa S, Karvonen U, Rasanen LA, Persson SG, Poso AR (1997) Androgen receptors and skeletal muscle composition in trotters treated with nandrolone laureate. Zentralbl Veterinarmed A 44:481-491
14. Inoue K, Yamasaki S, Fushiki T, Kano T, Moritani T, Itoh K, Sugimoto E (1993) Rapid increase in the number of androgen receptors following electrical stimulation of the rat muscle. Eur J Appl Physiol 66:134-140
15. Janssen PJ, Brinkmann AO, Boersma WJ, Van-der-Kwast TH (1994) Immunohistochemical detection of the androgen receptor with monoclonal antibody F39.4 in routinely processed, paraffin-embedded human tissues after microwave pre-treatment. J Histochem Cytochem 42:1169-1175
16. Joubert Y, Tobin C (1989) Satellite cell proliferation and increase in the number of myonuclei induced by testosterone in the levator ani muscle of the adult female rat. Dev Biol 131: 550-557
17. Kadi F, Hägg G, Håkansson R, Holmner S, Butler-Browne G, Thornell L-E (1998) Structural changes in male trapezius muscle with work-related myalgia. Acta Neuropathol 95: -352-360
18. Kadi F, Eriksson A, Holmner S, Butler-Browne G, Thornell L-E (1999a) Cellular adaptation of the trapezius muscle in strength trained athletes. Histochem Cell Biol 111:189-195
19. Kadi F, Eriksson A, Holmner S, Thornell L-E (1999b) Effects of anabolic steroids on the muscle cells of strength-trained athletes. Med Sci Sports Exerc 31 (in press)
20. Kimura N, Mizokami A, Oonuma T, Sasano H, Nagura H (1993) Immunocytochemical localization of androgen receptor with polyclonal antibody in paraffin-embedded human tissues. J Histochem Cytochem 41:671-678
21. Kochakian CD, Tillotson C (1957) Influence of several C19-steroids on the growth of individual muscles of the guinea pig. Endocrinology 60:607-618
22. Krieg M (1976) Characterization of the androgen receptor in the skeletal muscle of the rat. Steroids 28:261-274
23. Lin MC, Rajfer J, Swerdloff RS, Gonzalez-Cadavid NF (1993) Testosterone down-regulates the levels of androgen receptor mRNA in smooth muscle cells from the rat corpora cavernosa via aromatization to estrogens. J Steroid Biochem Mol Biol 45:333-343
24. Lindman R, Eriksson A, Thornell LE (1990) Fibre type composition of the human male trapezius muscle: Enzyme-histochemical characteristics. Am J Anat 189:236-244
25. Luke M, Coffey D (1994) The male accessory tissues: Structure, androgen, and physiology. In: Knobil E, Neill J (eds) The Physiology of Reproduction. Raven Press, New York, pp 1435-1488
26. Max SR, Mufti S, Carlson BM (1981) Cytosolic androgen receptor in regenerating rat levator ani muscle. Biochem J 200:77-82
27. Regnier M, Herrera AA (1993a) Differential sensitivity to androgens within a sexually dimorphic muscle of male frogs (Xenopus laevis). J Neurobiol 24:1215-1228
28. Regnier M, Herrera AA (1993b) Changes in contractile properties by androgen hormones in sexually dimorphic muscles of male frogs (Xenopus laevis). J Physiol Lond 461:565-581
29. Ruizeveld-de-Winter JA, Trapman J, Vermey M, Mulder E, Zegers ND, Van-der-Kwast TH (1991) Androgen receptor expression in human tissues: An immunohistochemical study. J Histochem Cytochem 39:927-936
30. Salmons S (1992) Myotrophic effects of an anabolic steroid in rabbit limb muscles. Muscle Nerve 15:806-812
31. Sar M, Lubahn DB, French FS, Wilson EM (1990) Immunohistochemical localization of the androgen receptor in rat and human tissues. Endocrinology 127:3180-3186
32. Stefanini M, De-Martino C, Zamboni L (1967) Fixation of ejaculated spermatozoa for electron microscopy. Nature 216:173-174
33. Syms AJ, Norris JS, Panko WB, Smith RG (1985) Mechanism of androgen-receptor augmentation. Analysis of receptor synthesis and degradation by the density-shift technique. J Biol Chem 260:455-461
34. Takeda H, Chodak G, Mutchnik S, Nakamoto T, Chang C (1990) Immunohistochemical localization of androgen receptors with mono- and polyclonal antibodies to androgen receptor. J Endocrinol 126:17-25
35. Trapman J, Klaassen P, Kuiper GG, Korput JA Van Der, Faber PW, Rooij HC Van, Geurts-van-Kessel A, Voorhorst MM, Mulder E, Brinkmann AO (1988) Cloning, structure and expression of a cDNA encoding the human androgen receptor. Biochem Biophys Res Commun 153:241-248
36. Wilson JD (1988) Androgen abuse by athletes. Endocr Rev 9:181-199
37. Winchester PK, Gonyea WJ (1992) A quantitative study of satellite cells and myonuclei in stretched avian slow tonic muscle. Anat Rec 232:369-377