Anticonvulsant induced osteomalacia

Indian Pediatrics

Volumn 37, Issue 3, 2000, Pages 325-329

  Goraya, Jatinder S ^a   Gupta, P N ^a   Gupta, Ravi K ^a   Bahadur, Raj ^a   Parmar, V R ^a  

^a GOVERNMENT MEDICAL COLLEGE AND HOSPITAL   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE BONE ISOENZYME; ANTICONVULSIVE AGENT; CALCIUM; CARBAMAZEPINE; PHENOBARBITAL; PHOSPHORUS; VITAMIN D;

ADOLESCENT; ARTICLE; CASE REPORT; DRUG INDUCED DISEASE; EPILEPSY; FEMALE; FEMUR FRACTURE; HUMAN; INFANT; KNEE RADIOGRAPHY; MALE; OSTEOMALACIA; PLASTER CAST; WRIST DISEASE; WRIST RADIOGRAPHY;

ADOLESCENT; ANTICONVULSANTS; CARBAMAZEPINE; EPILEPSY; FEMALE; HUMANS; INFANT; MALE; OSTEOMALACIA; PHENOBARBITAL; RISK FACTORS; VITAMIN D DEFICIENCY;

EID: 0034069709     PISSN: 00196061     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Hahn TJ. Bone complications of anticonvulsants. Drugs 1976; 12: 201-211.
2. Reynolds EH. Chronic antiepileptic toxicity. A Review. Epilepsia 1975; 16: 319-352.
3. Richens A, Rowe DJF. Disturbance of calcium metabolism by anticonvuisant drugs. BMJ 1970; 3: 73-76.
4. Lifshitz F, Maclaren NK. Vitamin D dependent rickets in institutionalized mentally retarded children receiving long term anticonvuisant therapy: A survey of 288 patients. J Pediatr 1973; 83: 612-620.
5. Tolman KG, Jubiz W, Sannella JJ, Madsen JA, Belsey RE, Gold Smith RS, et al. Osteomalacia associated with anticonvulsant drug therapy in mentally retarded children. Pediatrics 1975; 56: 45-50.
6. Hoikke V, Savolainen K, Alhava EM, Silvenius J, Karjalainen P, Repo A. Osteomalacia in institutionalized epileptic patients on long term anticonvulsant therapy. Acta Neurol Scand 1981; 64: 122-131.
7. Kruse R. Osteopathien bie antiepilaptischer Langeihterapie. Monatsselve Kinderheilkd 1968; 116: 378-381.
8. Dent CE, Richens A, Rowe DJF, Stamp TCB. Osteomalacia with-long term anticonvulsant therapy in epilapsy. BMJ 1970; 4: 69-72.
9. Borgstedt AD, Bryson MF, Young LW, Forbes GB. Long term administration of anti epileptic drugs and the development of rickets. J Pediatr 1972; 81: 9-15.
10. Baer MT, Kozlowski BW, Blyler EM, Taham CM, Taylor ML, Hogan MP. Vitamin D, calcium and bone status in children with development delay in relation to anticonvulsant use and ambulatory status. Am J Cllin Nutr 1997; 65: 1042-1051.
11. Mahapatro AK, Behari M, Prasad K, Ahuja GK. Phenytoin induced osteomalacia and fracture in a young epileptic. J Assoc Phys India. 1990; 38: 675-676.
12. Williams C, Netzolff M, Foklerts L, Vargas A, Garmica A, Frias J. Vitamin D, metabolism and anticonvulsant therapy: Effect of sunshine on incidence of osteomalacia. South Med J. 1984; 77: 834-836.
13. Rodbro P, Christiansen C, Lund M. Development of anticonvulsant osteomalacia in an epileptic patient on phenytoin treatment. Acta Neurol Scand, 1974; 50: 527-552.
14. Liakakos D, Papadonlos S, Vlashos P, Boviatsi E, Varonos DD. Serum alkaline phosphatase and urinary hydroxyproline values in children receiving phenobarbital with and without vitamin D. J Pediatr 1975; 87: 291-296.
15. Collins N, Maher J, Cole M, Baker N, Callaghan N. A prospective study to evaluate the dose of vitamin D required to correct low 25 hydroxy vitamin D, calcium and alkaline phosphatase in patients at risk of developing antiepileptic drug-inducted osteomalacia. QJ Med 1991, 78: 113-122.
16. Christiansen C, Rodbro P, Nielson CT. latrogenic osteomalacia in epileptic children. A controlled therapeutic trial. Acta Pediatr Scand 1975; 64: 219-224.