Expression of N-acetylglucosaminyltransferase V in colorectal cancer correlates with metastasis and poor prognosis

Clinical Cancer Research

Volumn 6, Issue 5, 2000, Pages 1772-1777

  Murata, Kohei ^a   Miyoshi, Eiji ^b   Kameyama, Masao ^a   Ishikawa, Osamu ^a   Kabuto, Toshiyuki ^a   Sasaki, Yo ^a   Hiratsuka, Masahiro ^a   Ohigashi, Hiroaki ^a   Ishiguro, Shingo ^a   Ito, Satoru ^c   Honda, Hideo ^c   Takemura, Fuminori ^c   Taniguchi, Naoyuki ^b   Imaoka, Shingi ^a  

^a OSAKA MEDICAL CENTER FOR CANCER AND CARDIOVASCULAR DISEASES   (Japan)

^b OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

^c Fujirebio Inc   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

N ACETYLGLUCOSAMINYLTRANSFERASE;

ADULT; AGED; ARTICLE; CANCER SURVIVAL; COLORECTAL CANCER; CORRELATION FUNCTION; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; METASTASIS; METASTASIS POTENTIAL; PRIORITY JOURNAL; PROGNOSIS; PROTEIN DETERMINATION; PROTEIN EXPRESSION;

AGED; AMINO ACID SEQUENCE; ANIMALS; COLORECTAL NEOPLASMS; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LYMPHATIC METASTASIS; MALE; MICE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; N-ACETYLGLUCOSAMINYLTRANSFERASES; NEOPLASM METASTASIS; NEOPLASM STAGING; PROGNOSIS; SURVIVAL RATE;

EID: 0034069025     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Pierce, M., Buckhaults, P., Chen, L., and Fregien, N. Regulation of N-acetylglucosaminyltransferase V and Asn-linked oligosaccharide β(1,6) branching by a growth factor signaling pathway and effects on cell adhesion and metastatic potential. Glycoconj. J., 14: 623-630, 1997.
2. Dennis, J. W., Laferte, S., Waghorne, C., Breitman, M. L., and Kerbel, R. S. Beta 1-6 branching of Asn-linked oligosaccharides is directly associated with metastasis. Science (Washington DC), 236: 582-585, 1987.
3. Kang, R., Saito, H., Ihara, Y., Miyoshi, E., Koyama, N., Sheng, Y., and Taniguchi, N. Transcriptional regulation of the N-acetylglucosaminyltransferase V gene in human bile duct carcinoma cells (HuCC-T1) is mediated by Ets-1. J. Biol. Chem., 271: 26706-26712, 1996.
4. Dennis, J. W., and Laferte, S. Oncodevelopmental expression of -GlcNAcβ1-6Manα1-6Manβ1-branched asparagine-linked oligosaccharides in murine tissues and human breast carcinomas. Cancer Res., 49: 945-950, 1989.
5. Miyoshi, E., Nishikawa, A., Ihara, Y., Gu, J., Sugiyama, T., Hayashi, N., Fusamoto, H., Kamada, T., and Taniguchi, N. N-acetylglucosaminyltransferase III and V messenger RNA levels in LEC rats during hepatocarcinogenesis. Cancer Res., 53: 3899-3902, 1993.
6. Miyoshi, E., Ihara, Y., Nishikawa, A., Saito, H., Uozumi, N., Hayashi, N., Fusamoto, H., Kamada, T., and Taniguchi, N. Gene expression of N-acetylglucosaminyltransferases III and V: a possible implication for liver regeneration. Hepatology, 22: 1847-1855, 1995.
7. Miyoshi, E., Nishikawa, A., Ihara, Y., Saito, H., Uozumi, N., Hayashi, N., Fusamoto, H., Kamada, T., and Taniguchi, N. Transforming growth factor β up-regulates expression of the N-acetylglucosaminyltransferase V gene in mouse melanoma cells. J. Biol. Chem., 270: 6216-6220, 1995.
8. Yao, M., Zhou, D. P., Jiang, S. M., Wang, Q. H., Zhou, X. D., Tang, Z. Y., and Gu, J. X. Elevated activity of N-acetylglucosaminyltrans-ferase V in human hepatocellular carcinoma. J. Cancer Res. Clin. Oncol., 124: 27-30, 1998.
9. Chen, L., Zhang, N., Adler, B., Browne, J., Freigen, N., and Pierce, M. Preparation of antisera to recombinant, soluble N-acetylglucosaminyltransferase V and its visualization in situ. Glycoconj. J., 12: 813-823, 1995.
10. Pierce, M., Arango, J., Tahir, S. H., and Hindsgaul, O. Activity of UDP-GlcNAc:alpha-mannoside beta(1,6)N-acetylglucosaminyltransferase (GnT V) in cultured cells using a synthetic trisaccharide acceptor. Biochem. Biophys. Res. Commun., 146: 679-684, 1987.
11. Gu, J., Nishikawa, A., Tsuruoka, N., Ohno, M., Yamaguchi, N., Kangawa, K, and Taniguchi, N. Purification and characterization of UDP-N-acetylglucosamine: alpha-6-D-mannoside beta 1-6N-acetylglucosaminyltransferase (N-acetylglucosaminyltransferase V) from a human lung cancer cell line. J. Biochem., 113: 614-619, 1993.
12. Shoreibah, M. G., Hindsgaul, O., and Pierce, M. Purification and characterization of rat kidney UDP-N-acetylglucosamine: α-6-D-mannoside β-1,6-N-acetylglucosaminyltransferase. J. Biol. Chem., 267: 2920-2927, 1992.
13. Park, C., Jin, U. H., Lee, Y. C., Cho, T. J., and Kim, C. H. Characterization of UDP-N-acetylglucosamine:α-6-D-mannoside β-1,6-N-acetylglucosaminyltransferase V from a human hepatoma cell line Hep3B. Arch. Biochem. Biophys., 367: 281-288, 1999.
14. Shoreibah, M., Perng, G. S., Adler, B., Weinstein, J., Basu, R., Cupples, R., Wen, D., Browne, J. K., Buckhaults, P., Fregien, N., and Pierce, M. Isolation, characterization, and expression of a cDNA encoding N-acetylglucosaminyltransferase V. J. Biol. Chem., 268: 15381-15385, 1993.
15. Saito, H., Nishikawa, A., Gu, J., Ihara, Y., Soejima, H., Wada, Y., Sekiya, C., Niikawa, N., and Taniguchi, N. cDNA cloning and chromosomal mapping of human N-acetylglucosaminyltransferase V. Biochem. Biophys. Res. Commun., 198: 318-327, 1994.
16. Fernandes, B., Sagman, U., Auger, M., Demetrio, M., and Dennis, J. W. β1-6 branched oligosaccharides as a marker of tumor progression in human breast and colon neoplasia. Cancer Res., 51: 718-723, 1991.
17. Takano, R., Nose, M., Nishihira, T., and Kyogoku, M. Increase of β1-6-branched oligosaccharides in human esophageal carcinomas invasive against surrounding tissue in vivo and in vitro. Am. J. Pathol., 137: 1007-1011, 1990.
18. Buckhaults, P., Chen, L., Fregien, N., and Pierce, M. Transcriptional regulation of N-acetylglucosaminyltransferase V by the src oncogene. J. Biol. Chem., 272: 19575-19581, 1997.
19. Lu, Y., and Chaney, W. Induction of N-acetylglucosaminyltransferase V by elevated expression of activated or proto-Ha-ras oncogenes. Mol. Cell. Biochem., 122: 85-92, 1993.
20. Demetriou, M., Nabi, I. R., Coppolino, M., Dedhar, S., and Dennis, J. W. Reduced contact-inhibition and substratum adhesion in epithelial cells expressing GlcNAc-transferase V, J. Cell. Biol., 130: 383-392, 1995.
21. Seberger, P. J., and Chaney, W. G. Control of metastasis by Asnlinked, β-6 branched oligosaccharides in mouse mammary cancer cells. Glycobiology, 9: 235-241, 1999.
22. Chen, L., Zhang, W., Fregien, N., and Pierce, M. The her-2/neu oncogene stimulates the transcription of N-acetylglucosaminyltransferase V and expression of its cell surface oligosaccharide products. Oncogene, 17: 2087-2093, 1998.
23. Ujita, M., McAuliffe, J., Hindsgaul, O., Sasaki, K., Fukuda, M. N., and Fukuda, M. Poly-N-acetyllactosamine synthesis in branched N-glycans is controlled by complemental branch specificity of i-extension enzyme and β1,4-galactosyltransferase I. J. Biol. Chem., 274: 16717-16726, 1999.
24. Saitoh, O., Wang, W.-C., Lotan, R., and Fukuda, M. Differential glycosylation and cell surface expression of lysosomal membrane glycoproteins in sublines of a human colon cancer exhibiting distinct metastatic potentials. J. Biol. Chem., 267: 5700-5711, 1992.
25. X antigen correlates with poor survival in patients with colorectal carcinoma: clinicopathological and immunohistochemical study. Cancer Res., 55: 3632-3637, 1993.
26. Shimodaira, K., Nakayama, J., Nakamura, N., Hasebe, O., Katsuyama, T., and Fukuda, M. Carcinoma-associated expression of core 2 β-1,6-N-acetylglucosaminyltransferase gene in human colorectal cancer: role of O-glycans in tumor progression. Cancer Res., 57: 5201-5206, 1997.
27. Nan, B. C., Shao, D. M., Chen, H. L., Huang, Y., Gu, J. X., Zhang, Y. B., and Wu, Z. G. Alteration of N-acetylglucosaminyltransferases in pancreatic carcinoma. Glycoconj. J., 15: 1033-1037, 1998.
28. Minsky, B. D., and Cohen, A. M. Blood vessel invasion in colorectal cancer - an alternative to TNM staging? Ann. Surg. Oncol., 6: 129-130, 1999.
29. Parshad, R. Adjuvant therapy in colorectal cancer. Trop. Gastroenterol., 18: 139-144, 1997.
30. Figueredo, A., Germond, C., Maroun, J., Browman, G, Walker-Dilks, C., and Wong, S. Adjuvant therapy for stage II colon cancer after complete resection. Provincial. Gastrointestinal Disease Site Group, Cancer Prev. Control, 1: 379-392, 1997.
31. Schrag, D. Defining optimal treatment for stage II colon cancer: does decision analysis help? Gastroenterology, 117: 1005-1008, 1999.
32. Goss, P. E., Baker, M. A., Carver, J. P., and Dennis, J. W. Inhibitors of carbohydrate processing: a new class of anticancer agents. Clin. Cancer Res., 1: 935-944, 1995.
33. Goss, P. E., Reid, C. L., Bailey, D., and Dennis, J. W. Phase IB clinical trial of the oligosaccharide processing inhibitor swainsonine in patients with advanced malignancies. Clin. Cancer Res., 3: 1077-1086, 1997.
34. Yagel, S., Feinmesser, R., Waghorne, C., Lala, P. K., Breitman, M. L., and Dennis, J. W. Evidence that β1-6 branched Asn-linked oligosaccharides on metastatic tumor cells facilitate invasion of basement membranes. Int. J. Cancer, 44: 685-690, 1989.
35. Dennis, J. W., Granovsky, M., and Warren, C. E. Protein glycosylation in development and disease. Bioessays, 21: 412-421, 1999.