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Volumn 9, Issue 2, 2000, Pages 279-288

Towards neurotransplantation in multiple system atrophy: Clinical rationale, pathophysiological basis, and preliminary experimental evidence

Author keywords

Multiple system atrophy; Neurotransplantation

Indexed keywords

8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; APOMORPHINE; DOPAMINE; DOPAMINE RECEPTOR; LEVODOPA; OXIDOPAMINE; QUINOLINIC ACID; SUBSTANCE P;

EID: 0034068074     PISSN: 09636897     EISSN: None     Source Type: Journal    
DOI: 10.1177/096368970000900213     Document Type: Article
Times cited : (32)

References (91)
  • 1
    • 84923949767 scopus 로고
    • Dégénérescences nigro-strieés et cérébello-nigro-strieés
    • Adams, R. D.; van Bogaert, L.; van der Ecken, H. Dégénérescences nigro-strieés et cérébello-nigro-strieés. Psychiatr. Neurol. 142:219-259; 1961.
    • (1961) Psychiatr. Neurol. , vol.142 , pp. 219-259
    • Adams, R.D.1    Van Bogaert, L.2    Van Der Ecken, H.3
  • 2
    • 0027970324 scopus 로고
    • Ibotenic acid lesions of the striatum reduce drug-induced rotation in the 6-hydroxydopamine-lesioned rat
    • Barker, R.; Dunnett, S. B. Ibotenic acid lesions of the striatum reduce drug-induced rotation in the 6-hydroxydopamine-lesioned rat. Exp. Brain. Res. 101:365-374; 1994.
    • (1994) Exp. Brain. Res. , vol.101 , pp. 365-374
    • Barker, R.1    Dunnett, S.B.2
  • 3
    • 0027433553 scopus 로고
    • Neurochemical and histologic characterization of striatal excitotoxic lesions produced by mitochondrial toxin 3-nitropropionic acid
    • Beal, M. F.; Brouillet, E.; Jenkins, B. G.; Ferrante, R. J.; Kowall, N. W.; Miller, J. M. Neurochemical and histologic characterization of striatal excitotoxic lesions produced by mitochondrial toxin 3-nitropropionic acid. J. Neurosci. 13:4181-4192; 1993.
    • (1993) J. Neurosci. , vol.13 , pp. 4181-4192
    • Beal, M.F.1    Brouillet, E.2    Jenkins, B.G.3    Ferrante, R.J.4    Kowall, N.W.5    Miller, J.M.6
  • 4
    • 0023713762 scopus 로고
    • Adrenal medulla grafts enhance functional activity of the striatal dopamine system following substantia nigra lesions
    • Becker, J. B.; Freed, W. J. Adrenal medulla grafts enhance functional activity of the striatal dopamine system following substantia nigra lesions. Brain Res. 462:401-406; 1988.
    • (1988) Brain Res. , vol.462 , pp. 401-406
    • Becker, J.B.1    Freed, W.J.2
  • 5
    • 0020076144 scopus 로고
    • Olivopontocerebellar atrophy. A review of 117 cases
    • Berciano, J. Olivopontocerebellar atrophy. A review of 117 cases. J. Neurol. Sci. 53:253-272; 1982.
    • (1982) J. Neurol. Sci. , vol.53 , pp. 253-272
    • Berciano, J.1
  • 6
    • 0030770812 scopus 로고    scopus 로고
    • Kinetics of nigral degeneration in chronic model of MPTP treated mice
    • Bezard, E.; Dovero, S.; Bioulac, B.; Gross, C. E. Kinetics of nigral degeneration in chronic model of MPTP treated mice. Neurosci. Lett. 234:47-50; 1997.
    • (1997) Neurosci. Lett. , vol.234 , pp. 47-50
    • Bezard, E.1    Dovero, S.2    Bioulac, B.3    Gross, C.E.4
  • 7
    • 0031865569 scopus 로고    scopus 로고
    • Experimental models of Parkinson's disease: From the static to the dynamic
    • Bezard, E.; Imbert, C.; Gross, C. E. Experimental models of Parkinson's disease: From the static to the dynamic. Rev. Neurosci. 9:71-90; 1998.
    • (1998) Rev. Neurosci. , vol.9 , pp. 71-90
    • Bezard, E.1    Imbert, C.2    Gross, C.E.3
  • 10
    • 0029565944 scopus 로고
    • Effects of chronic MPTP and 3-nitropropionic acid in nonhuman primates
    • Brouillet, E.; Hantraye, P. Effects of chronic MPTP and 3-nitropropionic acid in nonhuman primates. Curr. Opin. Neurol. 8:469-473; 1995.
    • (1995) Curr. Opin. Neurol. , vol.8 , pp. 469-473
    • Brouillet, E.1    Hantraye, P.2
  • 11
    • 0022648056 scopus 로고
    • Intrastriatal grafting of dopamine-containing neuronal cell suspensions: Effects of mixing with target or non-target cells
    • Brundin, P.; Isacson, O.; Gage, F. H.; Björklund, A. Intrastriatal grafting of dopamine-containing neuronal cell suspensions: Effects of mixing with target or non-target cells. Brain Res. 389:77-84; 1986.
    • (1986) Brain Res. , vol.389 , pp. 77-84
    • Brundin, P.1    Isacson, O.2    Gage, F.H.3    Björklund, A.4
  • 15
    • 0028169805 scopus 로고
    • Enhanced efficacy of nigral-striatal cotransplants in bilaterally dopamine-depleted rats: An anatomical and behavioral analysis
    • Costantini, L. C.; Vozza, B. M.; Snyder-Keller, A. M. Enhanced efficacy of nigral-striatal cotransplants in bilaterally dopamine-depleted rats: An anatomical and behavioral analysis. Exp. Neurol. 127:219-231; 1994.
    • (1994) Exp. Neurol. , vol.127 , pp. 219-231
    • Costantini, L.C.1    Vozza, B.M.2    Snyder-Keller, A.M.3
  • 16
    • 0031148851 scopus 로고    scopus 로고
    • Co-transplantation of fetal lateral ganglionic eminence and ventral mesencephalon can augment function and development of intrastriatal transplants
    • Costantini, L. C.; Snyder-Keller, A. Co-transplantation of fetal lateral ganglionic eminence and ventral mesencephalon can augment function and development of intrastriatal transplants. Exp. Neurol. 145:214-227; 1997.
    • (1997) Exp. Neurol. , vol.145 , pp. 214-227
    • Costantini, L.C.1    Snyder-Keller, A.2
  • 17
    • 0002949303 scopus 로고
    • The neuropathology and neurochemistry of multiple system atrophy
    • Bannister, R.; Mathias, C. J., eds. Oxford: Oxford University Press
    • Daniel, S. E. The neuropathology and neurochemistry of multiple system atrophy. In: Bannister, R.; Mathias, C. J., eds. A textbook of clinical disorders of autonomie nervous system. 3rd ed. Oxford: Oxford University Press; 1992: 564-585.
    • (1992) A Textbook of Clinical Disorders of Autonomie Nervous System. 3rd Ed. , pp. 564-585
    • Daniel, S.E.1
  • 19
    • 0024340117 scopus 로고
    • 3-Acetylpyridine-induced degeneration of the nigrostriatal dopamine system: An animal model of olivopontocerebellar atrophy-associated parkinsonism
    • Deutch, A. Y.; Rosin, D. L.; Goldstein, M.; Roth, R.H. 3-Acetylpyridine-induced degeneration of the nigrostriatal dopamine system: An animal model of olivopontocerebellar atrophy-associated parkinsonism. Exp. Neurol. 105: 1-9; 1989.
    • (1989) Exp. Neurol. , vol.105 , pp. 1-9
    • Deutch, A.Y.1    Rosin, D.L.2    Goldstein, M.3    Roth, R.H.4
  • 20
    • 0024992016 scopus 로고
    • 3-Acetylpyridine results in degeneration of the extrapyramidal and cerebellar motor systems: Loss of the dorsolateral striatal dopamine innervation
    • Deutch, A. Y.; Elsworth, J.D.; Roth, R. H.; Goldstein, M.; Deutsch, A. Y. 3-Acetylpyridine results in degeneration of the extrapyramidal and cerebellar motor systems: Loss of the dorsolateral striatal dopamine innervation. Brain Res. 527:96-102; 1990.
    • (1990) Brain Res. , vol.527 , pp. 96-102
    • Deutch, A.Y.1    Elsworth, J.D.2    Roth, R.H.3    Goldstein, M.4    Deutsch, A.Y.5
  • 21
    • 0019990992 scopus 로고
    • Sensorimotor impairment following localized kainic acid and 6-hydroxydopamine lesions of the striatum
    • Dunnett, S. B.; Iversen, S. D. Sensorimotor impairment following localized kainic acid and 6-hydroxydopamine lesions of the striatum. Brain Res. 248:121-127; 1982.
    • (1982) Brain Res. , vol.248 , pp. 121-127
    • Dunnett, S.B.1    Iversen, S.D.2
  • 22
    • 0025651148 scopus 로고
    • Striatonigral degeneration. A clinicopathological study
    • Fearnley, J. M.; Lees, A. J. Striatonigral degeneration. A clinicopathological study. Brain 113:1823-1842; 1990.
    • (1990) Brain , vol.113 , pp. 1823-1842
    • Fearnley, J.M.1    Lees, A.J.2
  • 23
    • 0028276809 scopus 로고
    • Implanted fibroblasts genetically engineered to produce brain-derived neurotrophic factor prevent 1-methyl-4-phenylpyridium toxicity to dopaminergic neurons in the rat
    • Frim, D. M.; Uhler, T. A.; Galpern, W. R.; Beal, M. F.; Breakefield, X.O.; Isacson, O. Implanted fibroblasts genetically engineered to produce brain-derived neurotrophic factor prevent 1-methyl-4-phenylpyridium toxicity to dopaminergic neurons in the rat. Proc. Natl. Acad. Sci. USA 91:5104-5108; 1994.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 5104-5108
    • Frim, D.M.1    Uhler, T.A.2    Galpern, W.R.3    Beal, M.F.4    Breakefield, X.O.5    Isacson, O.6
  • 25
    • 0031789960 scopus 로고    scopus 로고
    • Lewy body disease and multiple system atrophy as alpha-synucleinopathies
    • Goedert, M.; Spillantini, M. G. Lewy body disease and multiple system atrophy as alpha-synucleinopathies. Mol. Psychiatry 3:462-465; 1998.
    • (1998) Mol. Psychiatry , vol.3 , pp. 462-465
    • Goedert, M.1    Spillantini, M.G.2
  • 26
    • 0032904634 scopus 로고    scopus 로고
    • Alpha-synuclein and Parkinson's disease
    • Golbe, L. I. Alpha-synuclein and Parkinson's disease. Mov. Disord. 14:6-9; 1999.
    • (1999) Mov. Disord. , vol.14 , pp. 6-9
    • Golbe, L.I.1
  • 27
    • 0024835910 scopus 로고
    • Subdivisional involvement of nigrostriatal loop in idiopathic Parkinson's disease and nigrostriatal degeneration
    • Goto, S.; Hirano, A.; Matsumoto, S. Subdivisional involvement of nigrostriatal loop in idiopathic Parkinson's disease and nigrostriatal degeneration. Ann. Neurol. 26: 766-770; 1989.
    • (1989) Ann. Neurol. , vol.26 , pp. 766-770
    • Goto, S.1    Hirano, A.2    Matsumoto, S.3
  • 28
    • 0024421568 scopus 로고
    • Immunohistochemical visualization of afferent nerve terminals in human globus pallidus and its alteration in neostriatal neurodegenerative disorders
    • Goto, S.; Hirano, A.; Rojos-Corona, P. R. Immunohistochemical visualization of afferent nerve terminals in human globus pallidus and its alteration in neostriatal neurodegenerative disorders. Acta. Neuropathol. 78:543-550; 1989.
    • (1989) Acta. Neuropathol. , vol.78 , pp. 543-550
    • Goto, S.1    Hirano, A.2    Rojos-Corona, P.R.3
  • 29
    • 0025293675 scopus 로고
    • Met-enkephalin immunoreactivity in the basal ganglia in Parkinson's disease and striatonigral degeneration
    • Goto, S.; Hirano, A.; Matsumoto, S. Met-enkephalin immunoreactivity in the basal ganglia in Parkinson's disease and striatonigral degeneration. Neurology 40:1051-1056; 1990.
    • (1990) Neurology , vol.40 , pp. 1051-1056
    • Goto, S.1    Hirano, A.2    Matsumoto, S.3
  • 30
    • 0029805036 scopus 로고    scopus 로고
    • Subregional loss of putaminal efferents to the basal ganglia output nuclei may cause parkinsonism in striatonigral degeneration
    • Goto, S.; Matsumoto, J.; Ushio, Y.; Hirano, A. Subregional loss of putaminal efferents to the basal ganglia output nuclei may cause parkinsonism in striatonigral degeneration. Neurology 47:1032-36; 1996.
    • (1996) Neurology , vol.47 , pp. 1032-1036
    • Goto, S.1    Matsumoto, J.2    Ushio, Y.3    Hirano, A.4
  • 31
    • 0020465435 scopus 로고
    • Basal ganglia degeneration, myelin alterations, and enzyme inhibition induced in mice by the plant toxin 3-nitropropanoic acid
    • Gould, D. H.; Gustine, D. L. Basal ganglia degeneration, myelin alterations, and enzyme inhibition induced in mice by the plant toxin 3-nitropropanoic acid. Neuropathol. Appl. Neurobiol. 8:377-393; 1982.
    • (1982) Neuropathol. Appl. Neurobiol. , vol.8 , pp. 377-393
    • Gould, D.H.1    Gustine, D.L.2
  • 32
    • 0014469501 scopus 로고
    • Orthostatic hypotension and nicotine sensitivity in a case of multiple system atrophy
    • Graham, J. G.; Oppenheimer, D. R. Orthostatic hypotension and nicotine sensitivity in a case of multiple system atrophy. J. Neurol. Neurosurg. Psychiatry 32:28-34; 1969.
    • (1969) J. Neurol. Neurosurg. Psychiatry , vol.32 , pp. 28-34
    • Graham, J.G.1    Oppenheimer, D.R.2
  • 33
    • 0032692348 scopus 로고    scopus 로고
    • Sequential bilateral transplantation in Parkinson's disease: Effects of a second graft
    • in press
    • Hagell, P.; Schrag, A.; Piccini, P.; Jahanshahi, M.; Brown, R.; Rehncrona, S. Sequential bilateral transplantation in Parkinson's disease: Effects of a second graft. Brain (in press).
    • Brain
    • Hagell, P.1    Schrag, A.2    Piccini, P.3    Jahanshahi, M.4    Brown, R.5    Rehncrona, S.6
  • 34
    • 0018894295 scopus 로고
    • Circling behaviour in rats with partial, unilateral nigrostriatal lesions, effect of amphetamine, apomorphine, and L-dopa
    • Hefti, F.; Melamed, E.; Sahakian, B. J.; Wurtman, R. J. Circling behaviour in rats with partial, unilateral nigrostriatal lesions, effect of amphetamine, apomorphine, and L-dopa. Pharmacol. Biochem. Behav. 12:185-188; 1980.
    • (1980) Pharmacol. Biochem. Behav. , vol.12 , pp. 185-188
    • Hefti, F.1    Melamed, E.2    Sahakian, B.J.3    Wurtman, R.J.4
  • 35
    • 0026514953 scopus 로고
    • Accuracy of clinical diagnosis of idiopathic Parkinson's disease: A clinico-pathological study of 100 cases
    • Hughes, A. J.; Daniel, S. E.; Kilford, L.; Lees, A. J. Accuracy of clinical diagnosis of idiopathic Parkinson's disease: A clinico-pathological study of 100 cases. J. Neurol. Neurosurg. Psychiatry 55:181-184; 1992.
    • (1992) J. Neurol. Neurosurg. Psychiatry , vol.55 , pp. 181-184
    • Hughes, A.J.1    Daniel, S.E.2    Kilford, L.3    Lees, A.J.4
  • 36
    • 0029956583 scopus 로고    scopus 로고
    • Striatal efferent involvement and its correlation to levodopa efficacy in patients with multiple system atrophy
    • Ito, H., Kusaka, H.; Matsumoto, S.; Imai, T. Striatal efferent involvement and its correlation to levodopa efficacy in patients with multiple system atrophy. Neurology 47: 1291-1299; 1996.
    • (1996) Neurology , vol.47 , pp. 1291-1299
    • Ito, H.1    Kusaka, H.2    Matsumoto, S.3    Imai, T.4
  • 37
    • 0032143368 scopus 로고    scopus 로고
    • Characterization of behavioural and neurodegenerative changes following partial lesions of the nigrostriatal dopamine system induced by intrastriatal 6-hydroxydopamine in the rat
    • Kirik, D.; Rosenblad, C.; Björklund, A. Characterization of behavioural and neurodegenerative changes following partial lesions of the nigrostriatal dopamine system induced by intrastriatal 6-hydroxydopamine in the rat. Exp. Neurol. 152:259-277; 1998.
    • (1998) Exp. Neurol. , vol.152 , pp. 259-277
    • Kirik, D.1    Rosenblad, C.2    Björklund, A.3
  • 38
    • 0023874410 scopus 로고
    • Uneven pattern of dopamine loss in the striatum of patients with idiopathic Parkinson's disease: Pathologic and clinical implications
    • Kish, S. J.; Shannak, K.; Hornykiewicz, O. Uneven pattern of dopamine loss in the striatum of patients with idiopathic Parkinson's disease: Pathologic and clinical implications. N. Engl. J. Med. 318:876-880; 1988.
    • (1988) N. Engl. J. Med. , vol.318 , pp. 876-880
    • Kish, S.J.1    Shannak, K.2    Hornykiewicz, O.3
  • 39
    • 0027160963 scopus 로고
    • Neuronal cell loss of the striatonigral system in multiple system atrophy
    • Kume, A.; Takahashi, A.; Hashizume, Y. Neuronal cell loss of the striatonigral system in multiple system atrophy. J. Neurol. Sci. 117:33-40; 1993.
    • (1993) J. Neurol. Sci. , vol.117 , pp. 33-40
    • Kume, A.1    Takahashi, A.2    Hashizume, Y.3
  • 41
    • 0032531924 scopus 로고    scopus 로고
    • Parkinson's disease: Second of two parts
    • Lang, A. E.; Lozano, A. M. Parkinson's disease: Second of two parts. N. Engl. J. Med. 339:1130-1143; 1998.
    • (1998) N. Engl. J. Med. , vol.339 , pp. 1130-1143
    • Lang, A.E.1    Lozano, A.M.2
  • 42
    • 0028087201 scopus 로고
    • Cellular pathology of multiple system atrophy : A review
    • Lantos, P. L.; Papp, M. I. Cellular pathology of multiple system atrophy : A review. J. Neurol. Neurosurg. Psychiatry 57:129-133; 1994.
    • (1994) J. Neurol. Neurosurg. Psychiatry , vol.57 , pp. 129-133
    • Lantos, P.L.1    Papp, M.I.2
  • 43
    • 0031774904 scopus 로고    scopus 로고
    • The definition of multiple system atrophy: A review of recent developments
    • Lantos, P. L. The definition of multiple system atrophy: A review of recent developments. J. Neuropathol. Exp. Neurol. 57:1099-1111; 1998.
    • (1998) J. Neuropathol. Exp. Neurol. , vol.57 , pp. 1099-1111
    • Lantos, P.L.1
  • 44
    • 0029091879 scopus 로고
    • Time course of the neuroprotective effect of transplantation on quinolinic acid-induced lesions of the striatum
    • Levivier, M.; Gash, D. M.; Przedborski, S. Time course of the neuroprotective effect of transplantation on quinolinic acid-induced lesions of the striatum. Neuroscience 69:43-50; 1995.
    • (1995) Neuroscience , vol.69 , pp. 43-50
    • Levivier, M.1    Gash, D.M.2    Przedborski, S.3
  • 46
    • 0030773792 scopus 로고    scopus 로고
    • The pathobiology of the oligodendrocyte
    • Ludwin, S. L. The pathobiology of the oligodendrocyte. J. Neuropathol. Exp. Neurol. 56:11-124; 1997.
    • (1997) J. Neuropathol. Exp. Neurol. , vol.56 , pp. 11-124
    • Ludwin, S.L.1
  • 47
    • 0026101797 scopus 로고
    • The "staircase test": A measure of independent forelimb reaching and grasping abilities in rats
    • Montoya, C. P.; Campbell-Hope, L. J.; Pemberton, K. D.; Dunnett, S. B. The "staircase test": A measure of independent forelimb reaching and grasping abilities in rats. J. Neurosci. Methods 36(2-3):219-228; 1991.
    • (1991) J. Neurosci. Methods , vol.36 , Issue.2-3 , pp. 219-228
    • Montoya, C.P.1    Campbell-Hope, L.J.2    Pemberton, K.D.3    Dunnett, S.B.4
  • 48
    • 0030580581 scopus 로고    scopus 로고
    • Effects of alpha-phenyl-tert-butyl nitrone on neuronal survival and motor function following intrastriatal injections of quinolinate or 3-nitropropionic acid
    • Nakao, N.; Brundin, P. Effects of alpha-phenyl-tert-butyl nitrone on neuronal survival and motor function following intrastriatal injections of quinolinate or 3-nitropropionic acid. Neuroscience 76:749-761; 1997.
    • (1997) Neuroscience , vol.76 , pp. 749-761
    • Nakao, N.1    Brundin, P.2
  • 49
    • 0030041034 scopus 로고    scopus 로고
    • Fetal nigral transplantation as a therapy for Parkinson's disease
    • Olanow, C. W.; Kordower, J. H.; Freeman, T. B. Fetal nigral transplantation as a therapy for Parkinson's disease. Trends Neurosci. 19:102-109; 1996.
    • (1996) Trends Neurosci. , vol.19 , pp. 102-109
    • Olanow, C.W.1    Kordower, J.H.2    Freeman, T.B.3
  • 50
    • 0029064091 scopus 로고
    • Forelimb akinesia in the rat Parkinson model: Differential effects of dopamine agonists and nigral transplants as assessed by a new stepping test
    • Olsson, M.; Nikkhah, G.; Bentlage, C.; Björklund, A. Forelimb akinesia in the rat Parkinson model: Differential effects of dopamine agonists and nigral transplants as assessed by a new stepping test. J. Neurosci. 15:3863-3875; 1995.
    • (1995) J. Neurosci. , vol.15 , pp. 3863-3875
    • Olsson, M.1    Nikkhah, G.2    Bentlage, C.3    Björklund, A.4
  • 51
    • 0024843373 scopus 로고
    • Glial cytoplasmic inclusions in the CNS of patients with multiple system atrophy (striatonigral degeneration, olivopontocerebellar atrophy and Shy-Drager syndrome)
    • Papp, M. I.; Kahn, J. E.; Lantos, P. L. Glial cytoplasmic inclusions in the CNS of patients with multiple system atrophy (striatonigral degeneration, olivopontocerebellar atrophy and Shy-Drager syndrome). J. Neurol. Sci. 94:79-100; 1989.
    • (1989) J. Neurol. Sci. , vol.94 , pp. 79-100
    • Papp, M.I.1    Kahn, J.E.2    Lantos, P.L.3
  • 52
    • 0026543706 scopus 로고
    • Accumulation of tubular structures in oligodendroglial and neuronal cells as the basic alteration in multiple system atrophy
    • Papp, M. I.; Lantos, P. L. Accumulation of tubular structures in oligodendroglial and neuronal cells as the basic alteration in multiple system atrophy. J. Neurol. Sci. 107: 172-182; 1992.
    • (1992) J. Neurol. Sci. , vol.107 , pp. 172-182
    • Papp, M.I.1    Lantos, P.L.2
  • 53
    • 0028339722 scopus 로고
    • The distribution of oligodendroglial inclusions in multiple system atrophy and its relevance to clinical symptomatology
    • Papp, M. I.; Lantos, P. L. The distribution of oligodendroglial inclusions in multiple system atrophy and its relevance to clinical symptomatology. Brain 117:235-243; 1994.
    • (1994) Brain , vol.117 , pp. 235-243
    • Papp, M.I.1    Lantos, P.L.2
  • 55
    • 0030068021 scopus 로고    scopus 로고
    • What is needed versus what would be interesting to know before undertaking neural transplantation in patients with Huntington's disease
    • Peschanski, M.; Cesaro, P.; Hantraye, P. What is needed versus what would be interesting to know before undertaking neural transplantation in patients with Huntington's disease. Neuroscience 71:899-900; 1996.
    • (1996) Neuroscience , vol.71 , pp. 899-900
    • Peschanski, M.1    Cesaro, P.2    Hantraye, P.3
  • 59
    • 0017873531 scopus 로고
    • The rotating rodent: A two component system?
    • Pycock, C. J.; Marsden, C. D. The rotating rodent: A two component system? Eur. J. Pharmacol. 47:167-175; 1978.
    • (1978) Eur. J. Pharmacol. , vol.47 , pp. 167-175
    • Pycock, C.J.1    Marsden, C.D.2
  • 60
    • 0018652808 scopus 로고
    • 3H] spiperone binding in human caudate nucleus, substantia nigra and frontal cortex in the Shy-Drager syndrome and Parkinson's disease
    • 3H] spiperone binding in human caudate nucleus, substantia nigra and frontal cortex in the Shy-Drager syndrome and Parkinson's disease. J. Neurol. Sci. 43:429-437; 1979.
    • (1979) J. Neurol. Sci. , vol.43 , pp. 429-437
    • Quik, M.1    Spokes, E.G.2    Mackay, A.V.3    Bannister, R.4
  • 62
    • 0000016350 scopus 로고
    • Multiple system atrophy
    • Marsden, C. D.; Fahn, S., eds. London: Butterworth-Heinemann
    • Quinn, N. P. Multiple system atrophy. In: Marsden, C. D.; Fahn, S., eds. Movement disorders 3. London: Butterworth-Heinemann; 1994:262-281.
    • (1994) Movement Disorders 3 , pp. 262-281
    • Quinn, N.P.1
  • 63
    • 0025638918 scopus 로고
    • Levodopa efficacy and pathological basis of Parkinson syndrome
    • Rajput, A. H.; Rozdilsky, B.; Rajput, A.; Ang, L. Levodopa efficacy and pathological basis of Parkinson syndrome. Clin. Neuropharmacol. 13:553-558; 1990.
    • (1990) Clin. Neuropharmacol. , vol.13 , pp. 553-558
    • Rajput, A.H.1    Rozdilsky, B.2    Rajput, A.3    Ang, L.4
  • 64
    • 0028220834 scopus 로고
    • Progressive degeneration of nigrostriatal dopaminergic neurons following intrastriatal terminal lesions with 6-hydroxydopamine: A combined retrograde tracing and immunocytochemical study in the rat
    • Sauer, H.; Oertel, W. H. Progressive degeneration of nigrostriatal dopaminergic neurons following intrastriatal terminal lesions with 6-hydroxydopamine: A combined retrograde tracing and immunocytochemical study in the rat. Neuroscience 59:401-415; 1994.
    • (1994) Neuroscience , vol.59 , pp. 401-415
    • Sauer, H.1    Oertel, W.H.2
  • 66
    • 0342800537 scopus 로고    scopus 로고
    • Striatal neuroprotection in a double lesion animal model of striatonigral degeneration
    • in press
    • Scherfler, C.; Wenning, G. K.; Puschban, Z.; Weiler, B.; Poewe, W. Striatal neuroprotection in a double lesion animal model of striatonigral degeneration (abstract). J. Neural Transm. (in press).
    • J. Neural Transm.
    • Scherfler, C.1    Wenning, G.K.2    Puschban, Z.3    Weiler, B.4    Poewe, W.5
  • 67
    • 0021000670 scopus 로고
    • Intracerebral grafting of neuronal cell suspensions. III Activity of intrastriatal nigral suspension implants as assessed by measurement of dopamine synthesis and metabolism
    • Schmidt, R. H.; Björklund, A.; Stenevi, U.; Gage, F. H. Intracerebral grafting of neuronal cell suspensions. III Activity of intrastriatal nigral suspension implants as assessed by measurement of dopamine synthesis and metabolism. Acta Physiol. Scand. Suppl. 522:19-29; 1983.
    • (1983) Acta Physiol. Scand. Suppl. , vol.522 , pp. 19-29
    • Schmidt, R.H.1    Björklund, A.2    Stenevi, U.3    Gage, F.H.4
  • 69
    • 0026830133 scopus 로고
    • 123-iodobenzamide-SPECT predicts dopaminergic responsiveness in patients with de novo parkinsonism
    • Schwarz, J.; Tatsch, K.; Arnold, G.; Gasser, T.; Trenkwalder, C.; Kirsch, C. M. 123-iodobenzamide-SPECT predicts dopaminergic responsiveness in patients with de novo parkinsonism. Neurology 42:556-561; 1992.
    • (1992) Neurology , vol.42 , pp. 556-561
    • Schwarz, J.1    Tatsch, K.2    Arnold, G.3    Gasser, T.4    Trenkwalder, C.5    Kirsch, C.M.6
  • 70
    • 0030033775 scopus 로고    scopus 로고
    • Signal changes on MRI and increases in reactive microgliosis, astrogliosis, and iron in the putumen of two patients with multiple system atrophy
    • Schwarz, J.; Weis, S.; Kraft, E.; Tatsch, K.; Bandmann, O.; Mehraein, P.; Vogl. T. Signal changes on MRI and increases in reactive microgliosis, astrogliosis, and iron in the putumen of two patients with multiple system atrophy. J. Neurol. Neurosurg. Psychiatry. 60:98-101; 1996.
    • (1996) J. Neurol. Neurosurg. Psychiatry , vol.60 , pp. 98-101
    • Schwarz, J.1    Weis, S.2    Kraft, E.3    Tatsch, K.4    Bandmann, O.5    Mehraein, P.6    Vogl, T.7
  • 71
    • 0032517118 scopus 로고    scopus 로고
    • Microglial activation in multiple system atrophy: A potential role for NF-κB/rel proteins
    • Schwarz, S. C.; Seufferlein, T.; Liptay, S.; Schmid, R. M.; Kasischke, K.; Foster, O. J. F. Microglial activation in multiple system atrophy: A potential role for NF-κB/rel proteins. Neuroreport 9:3029-3032; 1998.
    • (1998) Neuroreport , vol.9 , pp. 3029-3032
    • Schwarz, S.C.1    Seufferlein, T.2    Liptay, S.3    Schmid, R.M.4    Kasischke, K.5    Foster, O.J.F.6
  • 73
    • 72849160194 scopus 로고
    • A neurological syndrome associated with orthostatic hypotension
    • Shy, G. M.; Draeger, G. A. A neurological syndrome associated with orthostatic hypotension. Arch. Neurol. 2: 511-527; 1960.
    • (1960) Arch. Neurol. , vol.2 , pp. 511-527
    • Shy, G.M.1    Draeger, G.A.2
  • 74
    • 0026447667 scopus 로고
    • Unilateral transplantation of human fetal mesencephalic tissue into the caudate nucleus of patients wilh Parkinson's disease
    • Spencer, D. D.; Robbins, R. J.; Naftolin, F.; Marek, K. L.; Vollmer, T.; Leranth, C. Unilateral transplantation of human fetal mesencephalic tissue into the caudate nucleus of patients wilh Parkinson's disease. N. Engl. J. Med. 327: 1541-1548; 1992.
    • (1992) N. Engl. J. Med. , vol.327 , pp. 1541-1548
    • Spencer, D.D.1    Robbins, R.J.2    Naftolin, F.3    Marek, K.L.4    Vollmer, T.5    Leranth, C.6
  • 76
    • 0027177628 scopus 로고
    • Blockade of 1-methyl-4-phenylpyridinium ion (MPP+) nigral toxicity in the rat by prior decortication or MK-801 treatment: A stereological estimate of neuronal loss
    • Srivastava, R.; Brouillet, E.; Beal, M. F.; Storey, E.; Hyman, B. T. Blockade of 1-methyl-4-phenylpyridinium ion (MPP+) nigral toxicity in the rat by prior decortication or MK-801 treatment: A stereological estimate of neuronal loss. Neurobiol. Aging 14:295-301; 1993.
    • (1993) Neurobiol. Aging , vol.14 , pp. 295-301
    • Srivastava, R.1    Brouillet, E.2    Beal, M.F.3    Storey, E.4    Hyman, B.T.5
  • 77
    • 0026719208 scopus 로고
    • 1-Methyl-4-phenylpyridinium produces excitotoxic lesions in rat striatum as a result of impairment of oxidative metabolism
    • Storey, E.; Hyman, B. T.; Jenkins, B.; Brouillet, E.; Miller, J. M.; Rosen, B. R. 1-Methyl-4-phenylpyridinium produces excitotoxic lesions in rat striatum as a result of impairment of oxidative metabolism. J. Neurochem. 58: 1975-1978; 1992.
    • (1992) J. Neurochem. , vol.58 , pp. 1975-1978
    • Storey, E.1    Hyman, B.T.2    Jenkins, B.3    Brouillet, E.4    Miller, J.M.5    Rosen, B.R.6
  • 78
    • 0027359489 scopus 로고
    • 3-Acetylpyridine neurotoxicity to the nigrostriatal dopamine system in mice
    • Takada, M.; Kono, T. 3-Acetylpyridine neurotoxicity to the nigrostriatal dopamine system in mice. Neurosci. Lett. 161:211-214; 1993.
    • (1993) Neurosci. Lett. , vol.161 , pp. 211-214
    • Takada, M.1    Kono, T.2
  • 79
    • 84982615966 scopus 로고
    • The pathophysiology of parkinsonism in multiple sytem atrophy
    • Tison, F.; Wenning, G. K.; Daniel, S.E.; Quinn, N. P. The pathophysiology of parkinsonism in multiple sytem atrophy. Eur. J. Neurol. 2:435-444; 1995.
    • (1995) Eur. J. Neurol. , vol.2 , pp. 435-444
    • Tison, F.1    Wenning, G.K.2    Daniel, S.E.3    Quinn, N.P.4
  • 81
    • 0027930620 scopus 로고
    • Clinical features and natural history of multiple system atrophy
    • Wenning, G. K.; Ben-Shlomo, Y.; Magalhaes, M.; Daniel, S. E.; Quinn, N. P. Clinical features and natural history of multiple system atrophy. Brain 117:835-845; 1994.
    • (1994) Brain , vol.117 , pp. 835-845
    • Wenning, G.K.1    Ben-Shlomo, Y.2    Magalhaes, M.3    Daniel, S.E.4    Quinn, N.P.5
  • 83
    • 0029814681 scopus 로고    scopus 로고
    • Reversal of behavioural abnormalities by fetal allografts in a novel rat model of striatonigral degeneration
    • Wenning, G. K.; Granata, R.; Laboyrie, P. M.; Quinn, N. P.; Jenner, P.; Marsden, C. D. Reversal of behavioural abnormalities by fetal allografts in a novel rat model of striatonigral degeneration. Mov. Disord. 11:522-532; 1996.
    • (1996) Mov. Disord. , vol.11 , pp. 522-532
    • Wenning, G.K.1    Granata, R.2    Laboyrie, P.M.3    Quinn, N.P.4    Jenner, P.5    Marsden, C.D.6
  • 84
    • 0342800525 scopus 로고    scopus 로고
    • Reversal of behavioural abnormalities in a rat model of striatonigral degeneration following intrastriatal transplantation of pure mesencephalic and mesencephalic-striatal co-grafts
    • Wenning, G. K.; Laboyrie, P.; Granata, R.; Quinn, N. P.; Jenner, P.; Marsden, C. D. Reversal of behavioural abnormalities in a rat model of striatonigral degeneration following intrastriatal transplantation of pure mesencephalic and mesencephalic-striatal co-grafts. Mov. Disord. 11:44; 1996.
    • (1996) Mov. Disord. , vol.11 , pp. 44
    • Wenning, G.K.1    Laboyrie, P.2    Granata, R.3    Quinn, N.P.4    Jenner, P.5    Marsden, C.D.6
  • 85
    • 0030986997 scopus 로고    scopus 로고
    • Multiple system atrophy: A review of 203 pathologically proven cases
    • Wenning, G. K.; Tison, F.; Ben-Shlomo, Y.; Daniel, S. E.; Quinn, N. P. Multiple system atrophy: A review of 203 pathologically proven cases. Mov. Disord. 12:133-147; 1997.
    • (1997) Mov. Disord. , vol.12 , pp. 133-147
    • Wenning, G.K.1    Tison, F.2    Ben-Shlomo, Y.3    Daniel, S.E.4    Quinn, N.P.5
  • 86
    • 0030834093 scopus 로고    scopus 로고
    • Short- and long-term survival and function of unilateral intrastriatal dopaminergic grafts in Parkinson's disease
    • Wenning, G. K.; Odin, P.; Morrish, P.; Rehncrona, S.; Widner, H.; Brundin, P. Short- and long-term survival and function of unilateral intrastriatal dopaminergic grafts in Parkinson's disease. Ann. Neurol. 42:95-107; 1997.
    • (1997) Ann. Neurol. , vol.42 , pp. 95-107
    • Wenning, G.K.1    Odin, P.2    Morrish, P.3    Rehncrona, S.4    Widner, H.5    Brundin, P.6
  • 88
    • 0342800522 scopus 로고    scopus 로고
    • A novel neural transplantation model of striatonigral degeneration using 3-nitropropionic acid
    • in press
    • Wenning, G. K.; Waldner, R.; Puschban, Z.; Scherfler, C.; Poewe, W. A novel neural transplantation model of striatonigral degeneration using 3-nitropropionic acid (abstract). J. Neural Transm. (in press).
    • J. Neural Transm.
    • Wenning, G.K.1    Waldner, R.2    Puschban, Z.3    Scherfler, C.4    Poewe, W.5
  • 89
    • 0025755396 scopus 로고
    • A comparison of excitotoxic lesions of the basal forebrain by kainate, quinolinate, ibotenate, N-methyl-D-aspartate or quisqualate, and the effect on toxicity of 2-amino-5-phosphonovaleric acid and kynurenic acid in the rat
    • Winn, P.; Stone, T. W.; Latimer, M.; Hastings, M. H.; Clark, A. J. A comparison of excitotoxic lesions of the basal forebrain by kainate, quinolinate, ibotenate, N-methyl-D-aspartate or quisqualate, and the effect on toxicity of 2-amino-5-phosphonovaleric acid and kynurenic acid in the rat. Br. J. Pharmacol. 102:904-908; 1991.
    • (1991) Br. J. Pharmacol. , vol.102 , pp. 904-908
    • Winn, P.1    Stone, T.W.2    Latimer, M.3    Hastings, M.H.4    Clark, A.J.5
  • 90
    • 0031587275 scopus 로고    scopus 로고
    • Evidence for an active type of cell death with ultrastructural features distinct from apoptosis: The effects of 3-acetylpyridine neurotoxicity
    • Wuellner, U.; Weller, N.; Groscurth, P.; Loschmann, P. A.; Schulz, J. B.; Müller, I. Evidence for an active type of cell death with ultrastructural features distinct from apoptosis: The effects of 3-acetylpyridine neurotoxicity. Neuroscience 81:721-734; 1997.
    • (1997) Neuroscience , vol.81 , pp. 721-734
    • Wuellner, U.1    Weller, N.2    Groscurth, P.3    Loschmann, P.A.4    Schulz, J.B.5    Müller, I.6
  • 91
    • 0025125222 scopus 로고
    • Embryonic mesencephalic and striatal co-grafts: Development of grafted dopamine neurons and functional recovery
    • Yurek, D. M.; Collier, T. J.; Sladek, J. R. Embryonic mesencephalic and striatal co-grafts: Development of grafted dopamine neurons and functional recovery. Exp. Neurol. 109:191-199; 1990.
    • (1990) Exp. Neurol. , vol.109 , pp. 191-199
    • Yurek, D.M.1    Collier, T.J.2    Sladek, J.R.3


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