메뉴 건너뛰기




Volumn 19, Issue 2, 2000, Pages 138-148

Sodium monochloroacetate causes cytotoxic effects, an increased lactate and pyruvate level and induces ultra structural and cytoskeletal alterations in cultured kidney and liver epithelial cells

Author keywords

Cytoskeleton; Cytotoxicity; Lactate; Mitochondria; Pyruvate; Sodium monochloroacetate

Indexed keywords

ACETIC ACID DERIVATIVE; CARBOXYMETHYLCELLULOSE; CHLOROACETATE SODIUM; CHLOROACETIC ACID; DYE; GLYCINE; LACTIC ACID; PHENOXYACETIC ACID; PYRUVIC ACID; THIOGLYCOLIC ACID; UNCLASSIFIED DRUG;

EID: 0034067980     PISSN: 09603271     EISSN: None     Source Type: Journal    
DOI: 10.1191/096032700678815693     Document Type: Article
Times cited : (12)

References (38)
  • 3
    • 0242312658 scopus 로고
    • Pediatric fatality associated with accidental oral administration of monochloroacetic acid (MCA)
    • Feldhaus K, et al. Pediatric fatality associated with accidental oral administration of monochloroacetic acid (MCA). Veterinary and Human Toxicology 1993; 35: 344.
    • (1993) Veterinary and Human Toxicology , vol.35 , pp. 344
    • Feldhaus, K.1
  • 4
    • 0026480916 scopus 로고
    • Fatal systemic poisoning after skin exposure to monochloroacetic acid
    • Kulling P, et al. Fatal systemic poisoning after skin exposure to monochloroacetic acid. Clinical Toxicology 1992; 30: 643-652.
    • (1992) Clinical Toxicology , vol.30 , pp. 643-652
    • Kulling, P.1
  • 11
    • 0021493652 scopus 로고    scopus 로고
    • Gas chromatography/mass spectroscopy analysis of mutagenic extracts of aqueous chlorinated humic acid. A comparison of the by-products to drinking water contaminants
    • Coleman WE, et al. Gas chromatography/mass spectroscopy analysis of mutagenic extracts of aqueous chlorinated humic acid. A comparison of the by-products to drinking water contaminants. Environmental Science and Toxicology 18: 674-681.
    • Environmental Science and Toxicology , vol.18 , pp. 674-681
    • Coleman, W.E.1
  • 12
    • 0024715922 scopus 로고
    • The occurrence of disinfection by-products in U.S. drinking water
    • Krasner SW, et al. The occurrence of disinfection by-products in U.S. drinking water. Journal of the American Water Works Association 1989; 81: 41-53.
    • (1989) Journal of the American Water Works Association , vol.81 , pp. 41-53
    • Krasner, S.W.1
  • 15
    • 0021934593 scopus 로고
    • Formation of glutathione conjugates by reactive metabolites of vinylidene chloride in microsomes and isolated hepatocytes
    • Liebler DC, Meredith MJ, Guengerich FP. Formation of glutathione conjugates by reactive metabolites of vinylidene chloride in microsomes and isolated hepatocytes. Cancer Research 1985; 45: 186-193.
    • (1985) Cancer Research , vol.45 , pp. 186-193
    • Liebler, D.C.1    Meredith, M.J.2    Guengerich, F.P.3
  • 16
    • 0017257491 scopus 로고
    • The mutagenicity of chloroethylene oxide, chloroacetaldehyde, 2-chloroethanol and chloroacetic acid, conceivable metabolites of vinyl chloride
    • Rannug U, Gothe R, Wachtmeister CA. The mutagenicity of chloroethylene oxide, chloroacetaldehyde, 2-chloroethanol and chloroacetic acid, conceivable metabolites of vinyl chloride. Chemico-Biological Interactions 1976; 12: 251-263.
    • (1976) Chemico-Biological Interactions , vol.12 , pp. 251-263
    • Rannug, U.1    Gothe, R.2    Wachtmeister, C.A.3
  • 19
  • 20
    • 0025357939 scopus 로고
    • Toxicokinetics of monochloroacetic acid: A whole-body autoradiography study
    • Bhat HK, Ahmed AE, Ansari GAS. Toxicokinetics of monochloroacetic acid: a whole-body autoradiography study. Toxicology 1990; 63: 35-43.
    • (1990) Toxicology , vol.63 , pp. 35-43
    • Bhat, H.K.1    Ahmed, A.E.2    Ansari, G.A.S.3
  • 21
    • 0015900920 scopus 로고
    • Differential toxicity of monochloroacetate, monofluoroacetate and monoiodoacetate in rats
    • Hayes FD, Short RD, Gibson JE. Differential toxicity of monochloroacetate, monofluoroacetate and monoiodoacetate in rats. Toxicology and Applied Pharmacology 1973; 26: 93-102.
    • (1973) Toxicology and Applied Pharmacology , vol.26 , pp. 93-102
    • Hayes, F.D.1    Short, R.D.2    Gibson, J.E.3
  • 22
    • 0018096851 scopus 로고
    • Establishment and characterization of a cell line from the American opossum (Didelphis virginiana)
    • Koyama H, et al. Establishment and characterization of a cell line from the American opossum (Didelphis virginiana). In Vitro 1978; 14: 239-246.
    • (1978) In Vitro , vol.14 , pp. 239-246
    • Koyama, H.1
  • 23
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mossman T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. Journal of Immunological Methods 1983; 65: 55-63.
    • (1983) Journal of Immunological Methods , vol.65 , pp. 55-63
    • Mossman, T.1
  • 24
    • 0021990499 scopus 로고
    • Toxicity determined in vitro by morphological alterations and neutral red absorption
    • Borenfreund E, Puerner J. Toxicity determined in vitro by morphological alterations and neutral red absorption. Toxicology Letters 1985; 24: 119-124.
    • (1985) Toxicology Letters , vol.24 , pp. 119-124
    • Borenfreund, E.1    Puerner, J.2
  • 26
    • 0001450646 scopus 로고
    • L-(+)-Lactat-Bestimmung mit Lactat-Dehydrogenase und NAD
    • Bergmeyer HU (ed). Auflage. Verlag Chemie: Weinheim
    • Gutmann I, Wahlefeld AW. L-(+)-Lactat-Bestimmung mit Lactat-Dehydrogenase und NAD. In Bergmeyer HU (ed) Methoden der enzymatischen Analyse, Bd. II, 3. Auflage. Verlag Chemie: Weinheim, 1974; pp 1510-1514.
    • (1974) Methoden der Enzymatischen Analyse, Bd. II, 3 , pp. 1510-1514
    • Gutmann, I.1    Wahlefeld, A.W.2
  • 27
    • 0001262581 scopus 로고
    • Pryvuat, Phosphoenolpyruvat und D-Glycerat-2-phosphat
    • Bergmeyer HU (ed). Auflage. Verlag Chemie: Weinheim
    • Czok R, Lamprecht W. Pryvuat, Phosphoenolpyruvat und D-Glycerat-2-phosphat. In Bergmeyer HU (ed) Methoden der enzymatischen Analyse, Bd. II, 3. Auflage. Verlag Chemie: Weinheim, 1974; pp 1491-1496.
    • (1974) Methoden der Enzymatischen Analyse, Bd. II, 3 , pp. 1491-1496
    • Czok, R.1    Lamprecht, W.2
  • 28
    • 0342653800 scopus 로고
    • Mounting media for epifluorescence microsopy. A comparative study on the cytoskeleton of cultivated lens epithelial cells
    • Dartsch PC. Mounting media for epifluorescence microsopy. A comparative study on the cytoskeleton of cultivated lens epithelial cells. GIT Labormedizin 1990; 13: 450-456.
    • (1990) GIT Labormedizin , vol.13 , pp. 450-456
    • Dartsch, P.C.1
  • 29
    • 0029091651 scopus 로고
    • Effects of calcium channel blockers on NIH 3T3 fibroblasts expressing the Ha-ras oncogene
    • Dartsch PC, et al. Effects of calcium channel blockers on NIH 3T3 fibroblasts expressing the Ha-ras oncogene. European Journal of Cell Biology 1995; 67: 372-378.
    • (1995) European Journal of Cell Biology , vol.67 , pp. 372-378
    • Dartsch, P.C.1
  • 31
    • 0027365916 scopus 로고
    • In vitro cytotoxicity of mono, di-and trichloroacetate and its modulation by hepatic peroxisome proliferation
    • Bruschi SA, Bull RJ. In vitro cytotoxicity of mono, di-and trichloroacetate and its modulation by hepatic peroxisome proliferation. Fundamental and Applied Toxicology 1993; 21: 366-375.
    • (1993) Fundamental and Applied Toxicology , vol.21 , pp. 366-375
    • Bruschi, S.A.1    Bull, R.J.2
  • 32
    • 0030869962 scopus 로고    scopus 로고
    • Comparative genotoxicity of halogenated acetic acids found in drinking water
    • Giller S, Le Curieux F, Erb F, Marzin D. Comparative genotoxicity of halogenated acetic acids found in drinking water. Mutagenesis 1997; 12: 321-328.
    • (1997) Mutagenesis , vol.12 , pp. 321-328
    • Giller, S.1    Le Curieux, F.2    Erb, F.3    Marzin, D.4
  • 34
    • 0342974803 scopus 로고
    • Monochloroacetic acid: Seven worldwide cases of systemic poisoning resulting from accidental skin contact
    • 22th ICOH-Congress, Sydney, MEDICHEM
    • Millischer RJ, et al. (1987). Monochloroacetic acid: seven worldwide cases of systemic poisoning resulting from accidental skin contact. Occupational Health in Chemical Industry. 22th ICOH-Congress, Sydney, MEDICHEM 1988; 138-144.
    • (1987) Occupational Health in Chemical Industry , pp. 138-144
    • Millischer, R.J.1
  • 35
    • 1842335839 scopus 로고
    • The toxicity of fluoroacetate and tricarboxylic acid cycle
    • Lieberg C, Peters RA. The toxicity of fluoroacetate and tricarboxylic acid cycle. Biochimica Biophysica Acta 1949; 3: 215-230.
    • (1949) Biochimica Biophysica Acta , vol.3 , pp. 215-230
    • Lieberg, C.1    Peters, R.A.2
  • 36
    • 0022553506 scopus 로고
    • Serum citrate as a peripheral indicator of fluoroacetate and fluorocitrate toxicity
    • Bosakowski T, Levin AA. Serum citrate as a peripheral indicator of fluoroacetate and fluorocitrate toxicity. Toxicology and Applied Pharmacology 1986; 85: 428-436.
    • (1986) Toxicology and Applied Pharmacology , vol.85 , pp. 428-436
    • Bosakowski, T.1    Levin, A.A.2
  • 37
    • 0026510835 scopus 로고
    • Toxicity of monochloroacetic acid administered by gavage to F344 rats and B6C3F1 mice for up to 13 weeks
    • Bryant BJ, et al. Toxicity of monochloroacetic acid administered by gavage to F344 rats and B6C3F1 mice for up to 13 weeks. Toxicology 1992; 72: 77-87.
    • (1992) Toxicology , vol.72 , pp. 77-87
    • Bryant, B.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.