Increasing neurite outgrowth capacity of β-amyloid precursor protein proteoglycan in Alzheimer's disease

Journal of Neuroscience Research

Volumn 60, Issue 1, 2000, Pages 87-97

  Salinero, Olga ^a   Moreno Flores, M Teresa ^a   Wandosell, Francisco ^a  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

Alzheimer's disease; Brain damage; Extracellular matrix; Neurite branching

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; LAMININ; PROTEOGLYCAN;

ALZHEIMER DISEASE; ANIMAL TISSUE; ARTICLE; CELL ADHESION; CONTROLLED STUDY; EXTRACELLULAR MATRIX; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; NERVE CELL; NERVE FIBER GROWTH; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN PROCESSING; PROTEIN PURIFICATION; RAT;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; ANTIBODIES; BLOTTING, WESTERN; CELL ADHESION; CHONDROITIN SULFATES; HIPPOCAMPUS; HUMANS; MIDDLE AGED; NEURITES; NEURONS; RATS;

EID: 0034066769     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(20000401)60:1<87::AID-JNR9>3.0.CO;2-C     Document Type: Article

References (46)

1. Araujo M, Cotman CW. 1992. β-Amyloid stimulate glial cells to produce growth factors that accumulate in senile plaques in Alzheimer's disease. Brain Res 569:141-145.
2. Araujo M, Wandosell FG. 1996. Differential cellular response after glutamate analogs brain damage. J Neurosci Res 44:397-409.
3. Behl C, Davis JB, Lesley R, Schubert D. 1994. Hydrogen peroxide mediates amyloid βprotein toxicity. Cell 77:817-827.
4. Breen KC, Bruce M, Anderton BH. 1991. Beta amyloid precursor protein mediates neuronal cell-cell and cell-surface adhesion. J Neurosci Res 28:90-100.
5. Bovolenta P, Wandosell F, Nieto-Sampedro M. 1993. Characterization of a neurite outgrowth inhibitor expressed after CNS injury. Eur J Neurosci 5:454-465.
6. Busciglio J, Gabuzda DH, Matsudaira P, Yankner BA. 1993. Generation of β-amyloid in the secretory pathway in neuronal and non-neuronal cells. Proc Natl Acad Sci USA 90:2092-2096.
7. Caporaso GL, Gandy SE, Buxbaum JD, Ramabhadran TV, Creengard P. 1992. Protein phosphorylation regulates secretion of Alzheimer β/A4 amyloid precursor protein. Proc Natl Acad Sci USA 89:3055-3059.
8. Esch FS, Keim PS, Beattie EC, Blacher RW, Culwell AR, Oltersdorf T, McClure D, Ward PJ. 1990. Cleavage of amyloid beta-peptide during constitutive processing of its precursor. Science 248:1122-1124.
9. Estus S, Golde TE, Kunishita T, Blades D, Lowery D, Eisen M, Usiak M, Qu X, Tabira T, Greenberg BD, Youkin SG. 1992. Potentially amyloidogenic, carboxy-terminal derivatives of the amyloid protein precursor. Science 255:726-728.
10. Fernaud-Espinosa I, Nieto-Sampedro M, Bovolenta P. 1994. Differential effects of glycosaminoglycans on neurite outgrowth from hippocampal and thalamic neurons. J Cell Sci 107:1437-1448.
11. Fukuyama R, Chandrasekaran K, Rapaport S. 1993. Nerve growth factor-induced neuronal differentiation is accompanied by differential induction and localization of the amyloid precursor protein (APP) in PC12 and PC12S cells. Mol Brain Res 17:17-22.
12. Golde TE, Estus S, Youkin LH, Selkoe DJ, Youkin SG. 1992. Processing of the amyloid protein precursor to potentially amyloidogenic derivatives. Science 255:728-730.
13. Gurd JW, Jones LR, Mahler HR, Moore WJ. 1974. Isolation and partial characterization of rat brain synaptic plasma membranes. J Neurochem 22:281-290.
14. Haas CA, Koo EH, Mellon A, Hung AY, Selkoe DJ. 1992. Targeting of cell surface β-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments. Nature 357:500-503.
15. Harlow E, Lane D. 1988. Antibodies: a laboratory manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.
16. Kang J, Lemaire H, Unterbeck A, Salbaum JM, Masters CL, Grzeschik K, Multhaup G, Beyreuther K, Müller Hill B. 1987. The precursor of Alzheimer disease amyloid A4 protein resembles a cell-surface receptor. Nature 325:733-736.
17. Kitaguchi N, Takahashi Y, Tokushima Y, Shiojiri S, Ito H. 1988. Novel precursor of Alzheimer disease shows protease inhibitor activity. Nature 311:530-532.
18. Koo EH, Park L, Selkoe DJ. 1993. Amyloid β-protein interacts with extracellular matrix to promote neurite outgrowth. Proc Natl Acad Sci USA 90:4748-4752.
19. Lafont F, Roouget M, Triller A, Prochiant A, Rousselet A. 1992. In vitro control of neuronal polarity by glycosaminoglycans. Development 114: 17-29.
20. Lemaire H, Salbaum JM, Multhaup G, Kang J, Bayney RM, Unterbeck A, Beyreuther K, Müller-Hill B. 1989. The preA4695 precursor protein of Alzheimer disease A4 amyloid is encoded by 16 exons. Nucleic Acids Res 17:517-522.
21. Milward EA, Papadopoulos R, Fuller SJ, Moir RD, Small D, Beyruther K, Masters CL. 1992. The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth. Neuron 9:129-137.
22. Morand JN, Kent C. 1986. A one-step technique for the subcellular fractionation of total cell homogenates. Anal Biochem 159:157-162.
23. Nordstedt C, Gandy SE, Alafuzoff I, Caporaso GL, Iverfeldt K, Grebb JA, Windbld B, Greengard P. 1991. Alzheimer βA4 precursor protein in human brain: aging associated increases in holoprotein and in a proteolytic fragment. Proc Natl Acad Sci USA 88:8910-8914.
24. Oltersdorf T, Fritz LC, Shenk DB, Lieberburg I, Johnson-Wood KL, Beattie EC, Ward PJ, Blacher RW, Dovey HF, Sinha S. 1989. The secreted form of the Alzheimer amyloid precursor protein with the Kunitz domain is protease nexin-II. Nature 341:144-147.
25. Pangalos MN, Efthimiopoulos S, Shioi J, Robakis N. 1995a. The chondroitin sulfate attachment site of appican is formed by splicing out exon 15 of the amyloid precursor gene. J Biol Chem 270:10388-10391.
26. Pangalos MN, Shioi J, Robakis NK. 1995b. Expression of the chondroitin sulfate proteoglycans of amyloid precursor (appican) and amyloid precursor-lilke protein 2. J Neurochem 65:762-769.
27. Ponte P, Gonzalez-DeWhitt P, Schilling J, Miller J, Hsu D, Greenberg B, Davis K, Wallace W, Lieberburg I, Fuller F, Cordell B. 1988. A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors. Nature 331:525-527.
28. Salinero O, Garrido JJ, Wandosell FG. 1998. β-Amyloid precursor protein proteoglycanis increased after brain damage. Biochim Biophys Acta 1046: 237-250.
29. Sandbrink R, Master CL, Beyreuther K. 1994. βA4-amyloid precursor protein mRNA isoform without exon15 are ubiquitously expresed in rat tissue including brain but not in neurons. J Biol Chem 269:1510-1517.
30. Schubert D, Jin LW, Saitoh T, Cole G. 1989. The regulation of amyloid protein precursor secretion and its modulatory role in cell adhesion. Neuron 3:689-694.
31. Shioi J, Anderson JP, Ripellino AJ, Robakis NK. 1992. Chondroitin sulfate proteoglycan form of Alzheimer's beta-amyloid precursor. J Biol Chem 264:13819-13822.
32. Shioi J, Refolo L, Efthimiopoulos S, Robakis NK. 1993. Chondroitin sulfate proteoglycan form of cellular and cell-surface Alzheimer amyloid precursor. Neurosci Lett 154:121-124.
33. Shioi J, Pangalos MN, Ripellino JA, Vassilacopoulou D, Mytilineou C, Margolis RU, Robakis NK. 1995. The Alzheimer amyloid precursor proteoglycan (appican) is present in brain and its produced by astrocytes but not by neurons in primary neural cultures. J Biol Chem 270:11839-11844.
34. Shoji M, Golde T, Ghiso J, Cheung T, Estus S, Shaffer L, Cai X, McKay D, Tinter R, Frangione B, Youkin S. 1992. Production of the Alzheimer β protein by normal proteolytic processing. Science 258:126-129.
35. Siman R, Card JP, Nelson RB, Davis LG. 1989. Expression of β-amyloid precursor protein in reactive astrocytes following neuronal damage. Neuron 3:275-285.
36. Slunt H, Thinakaran G, Von Koch C, Lo A, Tanzi R, Sisodia SS. 1994. Expression of a ubiquitous, cross-reactive homologue of the mouse β-amyloid precursor protein (APP). J Biol Chem 269:2637-2644.
37. Snow AD, Sekiguchi RT, Nochlin D, Fraser P, Kimata K, Mizutani A, Arai M, Schreire W, Morgan DG. 1994. An important role of heparansulfate proteoglycan (perlecan) in a model system for deposition and persistence of fibrillar Aβ-amyloid in rat brain. Neuron 12:219-234.
38. Tanzi RE, McClatchey AI, Lamperti ED, Villa-Komaroff L, Gusella JF, Neve RL. 1988. Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer disease. Nature 311:528-530.
39. Thinakaran G, Sisodia SS. 1994. Amyloid precursor-like protein 2 (APLP2) is modified by the addition of chondroitin sulfate glycosaminoglycan at a single site. J Biol Chem 269:22099-22104.
40. Thinakaran G, Slunt HH, Sisodia SS. 1995. Novel regulation of chondroiotin sulfate glycosaminoglycan modification of amyloid precursor protein and its homologue, APLP2. J Biol Chem 14:16522-16525.
41. Wandosell FG, Bovolenta P, Nieto-Sampedro M. 1993. Differences between reactive astrocytes and cultured astrocytes treated with di-butyrilcyclic AMP. J Neuropathol Exp Neurol 52:205-215.
42. Wang R, Meschia JF, Cotter RJ, Sisodia SS. 1991. Secretion of βA4 amyloid precursor protein. Identification of a cleavage site in mammalian cells. J Biol Chem 266:16960-16964.
43. Wasco W, Bupp K, Magendantz M, Gusella J, Tanzi R, Solomon F. 1992. Identification of a mouse brain cDNA that encodes a protein related to the Alzheimer disease-associated amyloid βprotein precursor. Proc Natl Acad Sci USA 89:10758-10762.
44. Weidmann A, Köning G, Bunke D, Fischer P. Salbaum JM, Masters CL, Beyreuther K. 1989. Identification, biogenesis and localization of precursor of Alzheimer's disease A4 amyloid protein. Cell 57:115-126.
45. Wu A, Pangalos MN, Efthimiopoulos S, Shioi J, Robakis N. 1997. Appican expresion induces morphological changes in C6 glioma cells and promote adhesion of neural cells to the extracellular matrix. J Neurosci 17:4987-4993.
46. Yankner BA, Davves LR, Fisher S, Villa-Komaroff L, Oster-Granite ML, Neve RL. 1989. Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease. Science 245:417-420.