Enzymatic reactivity and anti-tumor activity of 1-(β-D- arabinofuranosyl)-2-thiocytosine derivatives

Chemical and Pharmaceutical Bulletin

Volumn 48, Issue 4, 2000, Pages 454-457

  Kawaguchi, Takeo ^a   Ichikawa, Tomohisa ^a   Hasegawa, Tetsuya ^a   Saneyoshi, Mineo ^b   Wakayama, Toshiyuki ^c   Kato, Hisatoyo ^c   Yukita, Ayako ^c   Nagata, Toshiyuki ^c  

^a JOSAI UNIVERSITY   (Japan)

^b TEIKYO UNIVERSITY OF SCIENCE   (Japan)

^c Base Technology Center   (Japan)

Author keywords

1 ( D arabinofuranosyl) 2 thiocytosine; Enzymatic regeneration; P388; Prodrug; Tissue homogenate

Indexed keywords

AMIDE; CYTARABINE DERIVATIVE; ESTER DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG STRUCTURE; ENZYME ACTIVITY; MALE; MOUSE; NONHUMAN; SURVIVAL TIME; WEIGHT REDUCTION;

EID: 0034066453     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.48.454     Document Type: Article

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