Accurate multiplex polymerase chain reaction assay for gender determination from a single cell

Gynecologic and Obstetric Investigation

Volumn 49, Issue 4, 2000, Pages 217-220

  Hashiba, T ^a,b   Sueoka, K ^a   Kuroshima, M ^a   Asada, H ^a   Kuji, N ^a   Yoshimura, Y ^a  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b Dept of Obstetrics and Gynecology   (Japan)

Author keywords

DXZ1; DYZ1; Gender determination; Multiplex polymerase chain reaction; Preimplantation genetic diagnosis

Indexed keywords

AMNION CELL; ARTICLE; ASSAY; CELL ISOLATION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; FEMALE; FETUS CELL; HUMAN; HUMAN CELL; KARYOTYPING; MALE; MATERNAL BLOOD; POLYMERASE CHAIN REACTION; PREIMPLANTATION EMBRYO; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SEX DETERMINATION; SINGLE BLIND PROCEDURE; X CHROMOSOME; Y CHROMOSOME;

EID: 0034066333     PISSN: 03787346     EISSN: None     Source Type: Journal    
DOI: 10.1159/000010262     Document Type: Article

References (12)

1. Delhanty JDA: Preimplantation diagnosis. Prenat Diagn 1994;14:1217-1227.
2. Verlinsky Y, Handyside A, Grifo J, Munne S, Cohen J, Liebers I: Preimplantation diagnosis of genetic and chromosomal disorders. J Assist Reprod Genet 1994;11:236-243.
3. Simpson JL, Elias S: Isolating fetal cells in the maternal circulation for prenatal diagnosis. Prenat Diagn 1994;14:1229-1242.
4. Strom CM, Rechitsky S, Verlinsky Y: Reliability of gender determination using the polymerase chain reaction (PCR) for single cells. J In Vitro Fert Embryo Transf 1991;8:225-229.
5. Akane A, Seki S, Shiono H, Nakamura H, Hasegawa M, Kagawa M, Matsubara K, Nakahori Y, Nagafuchi S, Nakagome Y: Sex determination of forensic samples by dual PCR amplification of an X-Y homologous gene. Forensic Sci Int 1992;52:143-148.
6. Liu J, Lissen W, Devroey P, Steirteghem AV, Liebaers I: Amplification of X- and Y-chromosome specific regions from single human blastlomeres by polymerase chain reaction for sexing of preimplantation embryos. Hum Reprod 1994;9:716-720.
7. Chong SS, Kristjansson K, Cola J, Handyside AH, Hughes MR: Preimplantation prevention of X-linked disease: Reliable and rapid sex determination of single human cells by restriction analysis of simultaneously amplified ZFX and ZFY sequences. Hum Mol Genet 1993;2: 1187-1191.
8. Wave JS, Willard HF: Chromosome specific alpha satellite DNA: Nucleotide sequence analysis of the 2.0 kilobase-pair repeat from the human X chromosome. Nucleic Acids Res 1985;13:2731-2743.
9. Nakahori Y, Mitani K, Yamada M, Nakagome Y: A human Y-chromosome specific repeated DNA family (DYZ1) consists of a tandem array of pentanucleotides. Nucleic Acids Res 1986;14:7569-7579.
10. Kogan SC, Doherty M, Gitschier J: An improved method for prenatal diagnosis of genetic diseases by analysis of amplified DNA sequences. N Engl J Med 1987;317:985-990.
11. Handyside AH, Pattinson JK, Penketh RJA, Delhanty JDA, Winston RML, Tuddenham EG: Biopsy of human preimplantation embryos and sexing by DNA amplification. Lancet 1989;i:347-349.
12. Nakagome Y, Nagafuchi S, Seki S, Nakahori Y, Tamura T, Yamada M, Iwaya M: A repeating unit of the DYZ1 family on the human Y chromosome consists of segments with partial male specificity. Cytogenet Cell Genet 1991;56:74-77.