Endogenous MCP-1 influences systemic cytokine balance in a murine model of acute septic peritonitis

Experimental and Molecular Pathology

Volumn 68, Issue 2, 2000, Pages 77-84

  Matsukawa, Akihiro ^a   Hogaboam, Cory M ^a   Lukacs, Nickolas W ^a   Lincoln, Pamela M ^a   Strieter, Robert M ^a   Kunkel, Steven L ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Cytokine balance; Monocyte chemoattractant protein 1; Multiple organ failure; Sepsis

Indexed keywords

CYTOKINE; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 13; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLONY FORMING UNIT; CONTROLLED STUDY; EXPERIMENTAL MODEL; FEMALE; IMMUNE RESPONSE; IMMUNOREGULATION; INFLAMMATION; MOUSE; MULTIPLE ORGAN FAILURE; NONHUMAN; PERITONITIS; SEPSIS;

ANIMALIA; MURINAE;

EID: 0034065513     PISSN: 00144800     EISSN: None     Source Type: Journal    
DOI: 10.1006/exmp.1999.2296     Document Type: Article

References (29)

1. Astiz M. E., Rackow E. C. Septic shock. Lancet. 351:1998;1501-1505.
2. Ayala A., Deol Z. K., Lehman D. L., Herdon C. D., Chaudry I. H. Polymicrobial sepsis but not low-dose endotoxin infusion causes decreased splenocyte IL-2/IFN-γ release while increasing IL-4/IL-10 production. J. Surg. Res. 56:1994;579-585.
3. Baumhofer J. M., Beinhauer B. G., Wang J. E., Brandmeier H., Geissler K., Losert U., Philip R., Aversa G., Rogy M. A. Gene transfer with IL-4 and IL-13 improves survival in lethal endotoxemia in the mouse and ameliorates peritoneal macrophages immune competence. Eur. J. Immunol. 28:1998;610-615.
4. Bone R. C., Balk R. A., Cerra F. B., Dellinger R. P., Fein A. M., Knaus W. A., Schein R. M., Sibbald W. J. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Chest. 101:1992;1644-1655.
5. Bone R. C. Immunologic dissonance: A continuing evolution in our understanding of the systemic inflammatory response syndrome (SIRS) and the multiple organ dysfunction syndrome. Ann. Intern. Med. 125:1996;680-687.
6. Bossink A. W., Paemen L., Jansen P. M., Hack C. E., Thijs L. G., Van Damme J. Plasma levels of the chemokines monocyte chemotactic proteins-1 and -2 are elevated in human sepsis. Blood. 86:1995;3841-3847.
7. Colotta F., Re F., Muzio M., Polentarutti N., Minty A., Caput D., Ferrara P., Mantovani A. Interleukin-13 induces expression and release of interleukin-1 decoy receptor in human polymorphonuclear cells. J. Biol. Chem. 269:1994;12403-12406.
8. Colotta F., Saccani S., Giri J. G., Dower S. K., Sims J. E., Introna M., Mantovani A. Regulated expression and release of the IL-1 decoy receptor in human mononuclear phagocytes. J. Immunol. 156:1996;2534-2541.
9. Dai W. J., Kohler G., Brombacher F. Both innate and acquired immunity to Listeria monocytogenes infection are increased in IL-10-deficient mice. J. Immunol. 158:1997;2259-2267.
10. de Vries J. E. Molecular and biological characteristics of interleukin-13. Chem Immunol. 63:1996;204-218.
11. Faist E., Kim C. Therapeutic immunomodulatory approaches for the control of systemic inflammatory response syndrome and the prevention of sepsis. N. Horiz. 6:1998;S97-102.
12. Fink M. P., Heard S. O. Laboratory models of sepsis and septic shock. J. Surg. Res. 49:1990;186-196.
13. Hack C. E., Aarden L. A., Thijs L. G. Role of cytokines in sepsis. Adv. Immunol. 66:1997;101-195.
14. Hogaboam C. M., Steinhauser M. L., Schock H., Lukacs N. W., Strieter R. M., Standiford T. J., Kunkel S. L. Therapeutic effects of nitric oxide inhibition during experimental fecal perito nitis: role of interleukin-10 and monocyte chemoattractant protein 1. Infect. Immun. 66:1998;650-655.
15. Matsukawa A., Hogaboam C. M., Lukacs N. W., Lincoln P. M., Strieter R. M., Kunkel S. L. Endogenous monocyte chemoattractant protein-1 protects mice in a model of acute septic peritonit. Cross-talk between MCP-1 and leukotriene B4. J. Immunol. 163:1999;6148-6154.
16. Matsukawa A., Hogaboam C. M., Lukacs N. W., Lincoln P. M., Evanoff H. L., Strieter R. M., Kunkel S. L. Expression and contribution of endogenous IL-13 in an experimental model of sepsis. J. Immunal. 2000.
17. Muchamuel T., Menon S., Pisacane P., Howard M. C., Cockayne D. A. IL-13 protects mice from lipopolysaccharide-induced lethal endotoxemia: Correlation with down-modulation of TNF-α, IFN-γ, and IL-12 production. J. Immunol. 158:1997;2898-2903.
18. Nicoletti F., Mancuso G., Cusumano V., Di Marco R., Zaccone P., Bendtzen K., Teti G. Prevention of endotoxin-induced lethality in neonatal mice by interleukin-13. Eur. J. Immunol. 27:1997;1580-1583.
19. Parrillo J. E., Parker M. M., Natanson C., Suffredini A. F., Danner R. L., Cunnion R. E., Ognibene F. P. Septic shock in humans. Advances in the understanding of pathogenesis, cardiovascular dysfunction, and therapy. Ann. Intern. Med. 113:1990;227-242.
20. Steinhauser M. L., Hogaboam C. M., Kunkel S. L., Lukacs N. W., Strieter R. M., Standiford T. J. IL-10 is a major mediator of sepsis-induced impairment in lung antibacterial host defense. J. Immunol. 162:1999a;392-399.
21. Steinhauser M. L., Hogaboam C M., Lukacs N. W., Strieter R. M., Kunkel S. L. Multiple roles for interleukin 12 in a model of acute septic peritonitis. J. Immunol. 162:1999b;5437-5443.
22. van der Poll T., Marchant A., Keogh C. V., Goldman M., Lowry S. F. Interleukin-10 impairs host defense in murine pneumococcal pneumonia. J. Infect. Dis. 174:1996;994-1000.
23. Walley K. R., Lukacs N. W., Standiford T. J., Strieter R. M., Kunkel S. L. Balance of inflammatory cytokines related to severity and mortality of murine sepsis. Infect. Immun. 64:1996;4733-4738.
24. Yang X., Gartner J., Zhu L., Wang S., Brunham R. C. IL-10 gene knockout mice show enhanced Th1-like protective immunity and absent granuloma formation following Chlamydia trachomatis lung infection. J. Immunol. 162:1999;1010-1017.
25. Yang X., HayGlass K. T., Brunham R. C. Genetically determined differences in IL-10 and IFN-gamma responses correlate with clearance of Chlamydia trachomatis mouse pneumonitis infection. J. Immunol. 156:1996;4338-4344.
26. Yao Y. M., Redl H., Bahrami S., Schlag G. The inflammatory basis of trauma/shock-associated multiple organ failure. Inflamm. Res. 47:1998;201-210.
27. Yoshimura T., Ueda A. Monocyte Chemoattractant Protein-1. Aggarwal B. B., Gutterman J. U. Human Cytokines II: Handbook for Basic and Clinical Research. 1996;198-221 Blackwell Sci. Oxford.
28. Zisman D. A., Kunkel S. L., Strieter R. M., Tsai W. C., Bucknell K, Wilkowski J., Standiford T. J. MCP-1 protects mice in lethal endotoxemia. J. Clin. Invest. 99:1997;2832-2836.
29. Zurawski G., de Vries J. E. Interleukin 13, an interleukin 4-like cytokine that acts on monocytes and B cells, but not on T cells. Immunol. Today. 15:1994;19-26.