Autoantibodies to DEK oncoprotein in systemic lupus erythematosus (SLE)

Clinical and Experimental Immunology

Volumn 119, Issue 3, 2000, Pages 530-532

  Wichmann, I ^a   Respaldiza, N ^a   Garcia Lozano, J R ^a   Montes, M ^a   Sanchez Roman, J ^a   Nuñez Roldan, Antonio ^a  

^a HOSPITAL UNIVERSITARIO VIRGEN DEL ROCÍO   (Spain)

Author keywords

Autoantibodies; Autoimmunity; DEK protein; Systemic lupus erythematosus

Indexed keywords

AUTOANTIBODY; C REACTIVE PROTEIN; DNA ANTIBODY; ONCOPROTEIN;

ADOLESCENT; ADULT; AGED; ANEMIA; ANTIBODY DETECTION; ARTHRITIS; ARTICLE; CHILD; FEMALE; HUMAN; IMMUNOBLOTTING; IRIDOCYCLITIS; JUVENILE RHEUMATOID ARTHRITIS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SKIN MANIFESTATION; SYSTEMIC LUPUS ERYTHEMATOSUS;

EID: 0034064718     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.2000.01154.x     Document Type: Article

References (10)

1. 1 Von Lindern M, Fornerod M, van Baal S et al. The translocation (6;9) associated with a specific subtype of acute myeloid leukemia, results in the fusion of two genes, dek and can, and the expression of a chimeric, leukemia-specific dek-can mRNA. Mol Cell Biol 1992; 12:1687-97.
2. 2 Fu GK, Grosveld G, Markovitz DM. DEK, an autoantigen involved in a chromosomal translocation in acute myelogenous leukemia, binds to the HIV-2 enhancer. Proc Natl Acad Sci USA 1997; 94:1811-5.
3. 3 Sierakowska H, Williams KR, Szer IS, Szer W. The putative oncoprotein DEK, part of a chimera protein associated with acute myeloid leukemia, is an autoantigen in juvenile rheumatoid arthritis. Clin Exp Immunol 1993; 94:435-9.
4. 4 Szer IS, Sierakowska H, Szer W. A novel autoantibody to the putative oncoprotein DEK in pauciarticular onset juvenile rheumatoid arthritis. J Rheumatol 1994; 21:2136-42.
5. 5 Dong X, Michelis MA, Wang J, Bose R, DeLange T, Reeves WH. Autoantibodies to DEK oncoprotein in a patient with systemic lupus erythematosus and sarcoidosis. Arthritis Rheum 1998; 41:1505-10.
6. 6 Wichmann I, García-Lozano JR, Respaldiza N, Gonzalez-Escribano MF, Núñez-Roldán A. Autoantibodies to transcriptional regulation proteins DEK and ALY in a patient with systemic lupus erythematosus. Human Immunol 1999; 60:57-62.
7. 7 Tan EM, Cohen AS, Fries JF et al. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1982; 25:1271-7.
8. 8 Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1972; 227:680-5.
9. 9 Towbin H, Staiehelin T, Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA 1979; 76:4350-4.
10. 10 Hardin JA. The lupus autoantigens and the pathogenesis of SLE. Arthritis Rheum 1986; 29:457-60.