Strontium nitrate decreased histamine-induced itch magnitude and duration in man

Dermatology

Volumn 200, Issue 3, 2000, Pages 244-246

  Zhai, H ^a   Hannon, W ^a   Hahn, G S ^b   Harper, R A ^b   Pelosi, A ^a   Maibach, Howard I ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Cosmederm Technologies Inc ^*  (United States)

Author keywords

Antipruritic effects; Histamine; Strontium nitrate; Visual analogue scale

Indexed keywords

ANTIPRURITIC AGENT; HISTAMINE; STRONTIUM;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFECT; FEMALE; FOREARM; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; PRIORITY JOURNAL; PRURITUS; RANDOMIZED CONTROLLED TRIAL;

EID: 0034064443     PISSN: 10188665     EISSN: None     Source Type: Journal    
DOI: 10.1159/000018367     Document Type: Article

References (10)

1. Heyer GR, Hornstein OP: Recent studies of cutaneous nociception in atopic and non-atopic subjects. J Dermatol 1999;26:77-86.
2. Tuckett RP: Neurophysiology and neuroanatomy of pruritus; in Bernhard JD (ed): Itch Mechanisms and Management of Pruritus. New York, McGraw-Hill, 1994, pp 1-22.
3. Lerner EA: Chemical mediators of itching; in Bernhard JD (ed): Itch Mechanisms and Management of Pruritus. New York, McGraw-Hill, 1994, pp 23-35.
4. Hahn GS: Strontium is a potent and selective inhibitor of sensory irritation. Dermatol Surg 1999;25:689-694.
5. Zhai H, Hannon W, Hahn GS, Pelosi A, Harper RA, Maibach HI: Strontium nitrate suppresses chemically induced sensory irritation in humans. Contact Dermatitis 2000;42:98-100.
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8. Yosipovitch G, Maibach HI: Effects of topical pramoxinc on experimentally induced itch in man. J Am Acad Dermatol 1997;37:278-280.
9. Yosipovitch G, Szolar C, Hui XY, Maibach HI: High-potency topical corticosteroid rapidly decreases histamine-induced itch but not thermal sensation and pain in human beings. J Am Acad Dermatol 1996;35:118-120.
10. Yosipovitch G, Ademola J, Lui P, Amin S, Maibach HI: Topically applied aspirin rapidly decreases histamine-induced itch. Acta Derm Venereol 1997;77:46-48.