Transient receptor potential channels as molecular substrates of receptor-mediated cation entry

Journal of Molecular Medicine

Volumn 78, Issue 1, 2000, Pages 14-25

  Hofmann, Thomas ^a   Schaefer, Michael ^a   Schultz, Günter ^a   Gudermann, Thomas ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Calcium; Receptor stimulated channel; Store operated channel; Transient receptor potential; TRP homologous channel

Indexed keywords

CALCIUM; CALCIUM CHANNEL; GUANINE NUCLEOTIDE BINDING PROTEIN; PROTEIN TYROSINE KINASE;

CALCIUM TRANSPORT; CHANNEL GATING; DROSOPHILA MELANOGASTER; EUKARYOTIC CELL; MOLECULAR CLONING; NONHUMAN; PHOTORECEPTOR; PHOTOTRANSDUCTION; RECEPTOR POTENTIAL; REVIEW; SECOND MESSENGER; SEQUENCE HOMOLOGY; TISSUE DISTRIBUTION;

EID: 0034063461     PISSN: 09462716     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001099900070     Document Type: Review

References (113)

1. 1.Divecha N, Irvine RF (1995) Phospholipid signaling. Cell 80:269-278
2. 2+ from a nonmitochondrial intracellular store in pancreatic acinar cells by inositol-(1,4,5)-trisphosphate. Nature 306:67-69
3. 3. Kishimoto A, Takai Y, Mori T, Kikkawa U, Nishizuka Y (1980) Activation of calcium and phospholipid-dependent protein kinase by diacylglycerol, its possible relation to phosphatidylinositol turnover. J Biol Chem 255:2273-2276
4. 4. Mellor H, Parker PJ (1998) The extended protein kinase C superfamily. Biochem J 332:281-292
5. 5. Berridge MJ (1993) Inositol trisphosphate and calcium signalling. Nature 361:315-325
6. 6. Jones WJ (1998) Overview of voltage-operated calcium channels. J Bioenerg Biomemb 30:299-312
7. 7. Mozhayeva GN, Naumov AP, Kuryshev YA (1989) Epidermal growth factor activates calcium-permeable channels in A431 cells. Biophys Acta 1011:171-175
8. 2+ channels by phospholipase C-γ1 in glomerular mesangial cells. Am J Physiol 271:F994-F1003
9. 2+ channels: activation by phospholipase Cγ. Kidney Int 53:1259-1268
10. 10. Benham CD, Bolton TB, Lang RJ (1985) Acetylcholine activates an inward current in single mammalian smooth muscle cells. Nature 316:345-347
11. 2+-permeable channel activated by ATP in smooth muscle. Nature 328:275-278
12. 12. Benham CD, Tsien RW (1988) Noradrenaline modulation of calcium channels in single smooth muscle cells from rabbit ear artery. J Physiol (Lond) 404:767-784
13. 13. Van Renterghem C, Romey G, Lazdunski M (1988) Vasopressin modulates the spontaneous electrical activity in aortic cells (line A7r5) by acting on three different types of ionic channels. Proc Natl Acad Sci USA 85:9365-9369
14. 14. Kuriyama H, Kitamura K, Nabata H (1995) Pharmacological and physiological significance of ion channels and factors that modulate them in vascular tissues. Pharmacol Rev 47:387-573
15. 15. Kuriyama H, Kitamura K, Itoh T, Inoue R (1998) Physiological features of visceral smooth muscle cells, with special reference to receptors and ion channels. Physiol Rev 78:811-920
16. 2+ influx through receptor-mediated activation of nonspecific cation channels in mast cells. Proc Natl Acad Sci USA 90:3068-3072
17. 17. Kaupp UB, Niidome T, Tanabe T, Terada S, Bonigk W, Stuhmer W, Cook NJ, Kangawa K, Matsuo H, Hirose T, et al (1989) Primary structure and functional expression from complementary DNA of the rod photoreceptor cyclic GMP-gated channel. Nature 342:762-766
18. 18. Biel M, Zong X, Ludwig A, Sautter A, Hofmann F (1999) Structure and function of cyclic nucleotide-gated channels. Rev Physiol Biochem Pharmacol 135:151-171
19. 19. DiFrancesco D, Tortora P (1991) Direct activation of cardiac pacemaker channels by intracellular cyclic AMP. Nature 351: 145-147
20. 20. Gauss R, Seifert R, Kaupp UB (1998) Molecular identification of a hyperpolarization-activated channel in sea urchin sperm. Nature 393:583-587
21. 21. Ludwig A, Zong X, Jeglitsch M, Hofmann F, Biel M (1998) A family of hyperpolarization-activated mammalian cation channels. Nature 393:587-591
22. 22. Santoro B, Liu DT, Yao H, Bartsch D, Kandel ER, Siegelbaum SA, Tibbs GR (1998) Identification of a gene encoding a hyperpolarization-activated pacemaker channel of brain. Cell 93:717-729
23. 23. von Tscharner V, Prod'hom B, Baggiolini M, Reuter H (1986) Ion channels in human neutrophils activated by a rise in free cytosolic calcium concentration. Nature 324:369-372
24. 24. Loirand G, Pacaud P, Baron A, Mironneau C, Mironneau J (1991) Large conductance calcium-activated non-selective cation channel in smooth muscle cells isolated from rat portal vein. J Physiol (Lond) 437:461-475
25. 2+-permeable large-conductance non-selective cation channels in rat basophilic leukemia cells. Am J Physiol 269:C1119-C1125
26. 26. Kuno M, Gardner P (1987) Ion channels activated by inositol-(1,4,5)-trisphosphate in plasma membrane of human T-lymphocytes. Nature 326:301-304
27. 27. Matthews G, Neher E, Penner R (1989) Second-messenger-activated calcium influx in rat peritoneal mast cells. J Physiol (Lond) 418:105-130
28. 28. Penner R, Matthews G, Neher E (1988) Regulation of calcium influx by second messengers in rat mast cells. Nature 334:499-504
29. 2+ channels in plasma membrane of A431 carcinoma cells. FEBS Lett 407:309-312
30. 3. Pflügers Arch 437:305-314
31. 2+-permeable channel. Nature 355:356-358
32. 4 production. Cell 69:295-303
33. 2+ entry in HEK293 cells is independent of phospholipase C. J Biol Chem 273:32636-32643
34. 2+ entry mechanism in rat A7r5 smooth muscle cells stimulated with low concentrations of vasopressin. J Physiol (Lond) 517:121-134
35. 35. Hoth M, Penner R (1992) Depletion of intracellular calcium stores activates a calcium current in mast cells. Nature 355: 353-356
36. 36. Hoth M, Penner R (1993) Calcium release-activated calcium current in rat mast cells. J Physiol (Lond) 465:359-386
37. 2+ stores. Proc Natl Acad Sci USA 90:6296-6299
38. 2+ channel in Jurkat T-lymphocytes. Science 283:836-839
39. crac) due to local calcium feedback. J Gen Physiol 105:209-226
40. 40. Lückhoff A, Clapham DE (1994) Calcium channels activated by depletion of internal calcium stores in A431 cells. Biophys J 67:177-182
41. 2+-selective channel in vascular endothelium. Am J Physiol 267:C920-C925
42. 42. Krause E, Pfeiffer F, Schmid A, Schulz I (1996) Depletion of intracellular calcium stores activates a calcium conducting cation current in mouse pancreatic acinar cells. J Biol Chem 271:32523-32528
43. 2+ entry by inositol phosphates - a possible mechanism. FEBS Lett 263:5-9
44. 2+ influx. Nature 364:809-814
45. 2+ current in Xenopus oocytes requires SNAP-25 but not a diffusible messenger. Cell 98:475-485
46. 2+ enty: evidence for a secretion-like coupling model. Cell 98:487-499
47. 47. Holda JR, Blatter LA (1997) Capacitative calcium entry is inhibited in vascular endothelial cells by disruption of cytoskeletal microfilaments. FEBS Lett 403:191-196
48. 48. Hardie RC (1991) Whole-cell recordings of the light induced current in dissociated Drosophila photoreceptors: evidence for feedback by calcium permeating the light-sensitive channels. Proc R Soc Lond B Biol Sci 245:203-210
49. 2+ concentration in Drosophila photoreceptors. J Neurosci 16:2924-2933
50. 50. Scott K, Sun Y, Beckingham K, Zuker CS (1997) Calmodulin regulation of Drosophila light-activated channels and receptor function mediated termination of the light response in vivo. Cell 91:375-383
51. 51. Montell C, Rubin MR (1989) Molecular characterization of the Drosophila trp locus: a putative integral membrane protein required for phototransduction. Neuron 2:1313-1323
52. 52. Phillips AM, Bull A, Kelly LE (1992) Identification of a Drosophila gene encoding a calmodulin-binding protein with homology to the trp phototransduction gene. Neuron 8:631-642
53. 53. Vannier B, Zhu X, Brown D, Birnbaumer L (1998) The membrane topology of human transient receptor potential 3 as inferred from glycosylation-scanning mutagenesis and epitope immunocytochemistry. J Biol Chem 293:8675-8679
54. 54. Vaca L, Sinkins WG, Hu Y, Kunze DL, Schilling WP (1994) Activation of recombinant TRP by thapsigargin in Sf9 cells. Am J Physiol 267:C1501-C1505
55. 55. Petersen CCH, Berridge MJ, Borgese MF, Bennett DL (1995) Putative capacitive calcium entry channels: expression of Drosophila TRP and evidence for the existence of vertebrate homologues. Biochem J 311:41-44
56. 56. Xu XZS, Li HS, Guggino WB, Montell C (1997) Coassembly of TRP and TRPL produces a distinct store-operated conductance. Cell 89:1155-1164
57. 57. Sinkins WG, Vaca L, Hu Y, Kunze DL, Schilling WP (1996) The COOH-terminal domain of Drosophila TRP channels confers thapsigargin sensitivity. J Biol Chem 271:2955-2960
58. 58. Peretz A, Suss-Toby E, Rom-Glas A, Arnon A, Payne R, Minke B (1994) The light response of Drosophila photoreceptors is accompanied by an increase in cellular calcium: effects of specific mutations. Neuron 12:1257-1267
59. 59. Ranganathan R, Bacskai BJ, Tsien RY, Zuker CS (1994) Cytosolic calcium transients: spatial localization and role in Drosophila photoreceptor cell function. Neuron 13:837-848
60. 3 receptor is essential for growth and differentiation but not for vision in Drosophila. Neuron 18:881-887
61. 61. Scott K, Zuker CS (1998) TRP, TRPL and trouble in photoreceptor cells. Curr Opin Neurobiol 8:383-388
62. 62. Reuss H, Mojet MH, Chyb S, Hardie RC (1997) In vivo analysis of the Drosophila light-sensitive channels, TRP and TRPL. Neuron 19:1249-1259
63. 63. Obukhov AG, Schultz G, Lückhoff A (1998) Regulation of heterologously expressed transient receptor potential-like channels by calcium ions. Neuroscience 85:487-495
64. 64. Kunze DL, Sinkins WG, Vaca L, Schilling WP (1997) Properties of single TRPL channels expressed in Sf9 insect cells. Am J Physiol 272:C27-C34
65. 2+ influx pathway in Sf9 insect cells following expression of the transient receptor potential-like (TRPL) protein of Drosophila. Biochem Biophys Res Commun 201:1050-1056
66. 66. Hu Y, Schilling WP (1995) Receptor-mediated activation of recombinant TRPL expressed in Sf9 insect cells. Biochem J 305:605-611
67. 67. Harteneck C, Obukhov AG, Zobel A, Kalkbrenner F, Schultz G (1995) The Drosophila cation channel TRPL expressed in insect Sf9 cells is stimulated by agonists of G-protein-coupled receptors. FEBS Lett 358:297-300
68. 3 activates Drosophila cation channel TRPL in recombinant baculovirus-infected Sf9 insect cells. Am J Physiol 269: C1332-C1339
69. 3 is not sufficient. Cell Calcium 24:153-163
70. 11 subunits. EMBO J 15:5833-5838
71. 71. Chyb S, Raghu P, Hardie RC (1999) Polyunsaturated fatty acids activate the Drosophila light-sensitive channels TRP and TRPL. Nature 397:255-259
72. 2+ channel essential for phosphoinositide-mediated photoreception, forms a signaling complex with NorpA, InaC and InaD. EMBO J 15:7036-7045
73. 73. Chevesich J, Kreuz AJ, Montell C (1997) Requirement for the PDZ domain protein, INAD, for localization of the TRP store-operated channel to a signaling complex. Neuron 18:95-105
74. 2+ channel assembled in a signaling complex by the PDZ domain protein INAD is phosphorylated through the interaction with protein kinase C (ePKC). FEBS Lett 425:317-322
75. 75. Montell C (1998) TRP trapped in fly signaling web. Curr Opin Neurobiol 8:389-397
76. 76. Scott K, Zuker CS (1998) Assembly of the Drosophila phototransduction cascade into a signalling complex shapes elementary responses. Nature 395:805-808
77. 2+ entry. Proc Natl Acad Sci USA 93:14146-14151
78. 78. Tsunoda S, Sierralta J, Sun Y, Bodner R, Suzuki E, Becker A, Socolich M, Zuker CS (1997) A multivalent PDZ-domain protein assembles signaling complexes in a G-protein-coupled cascade. Nature 388:243-249
79. 79. Monk PD, Carne A, Liu SH, Ford JW, Keen JN, Findlay JB (1996) Isolation, cloning, and characterisation of a TRP homologue from squid (Loligo forbesi) photoreceptor membranes. J Neurochem 67:2227-2235
80. 80. Caterina MJ, Schumacher MA, Tominaga M, Rosen TA, Levine JD, Julius D (1997) The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 389:816-824
81. 81. Caterina MJ, Rosen TA, Tominaga M, Brake AJ, Julius D (1999) A capsaicin-receptor homologue with a high threshold for noxious heat. Nature 398:436-441
82. 82. Hunter JJ, Shao J, Smutko JS, Dussault BJ, Nagle DL, Woolf EA, Holmgren LM, Moore KJ, Shyjan AW (1998) Chromosomal localization and genomic characterization of the mouse melastatin gene (M1sn1). Genomics 54:116-123
83. 2+ channel protein (TRPC7) highly expressed in brain. Genomics 54:124-131
84. 84. Wes P, Chevesich J, Jeromin A, Rosenberg C, Stetten G, Montell C (1995) TRPC1, a human homolog of a Drosophila store-operated channel. Proc Natl Acad Sci USA 92:9652-9656
85. 85. Zhu X, Chu PB, Peyton M, Birnbaumer L (1995) Molecular cloning of a widely expressed human homologue for the Drosophila trp gene. FEBS Lett 373:193-198
86. 2+-permeable cation channel activated by store depletion. Neuron 16:1189-1196
87. 87. Wang W, O'Connell B, Dykeman R, Sakai T, Delporte C, Swaim W, Zhu X, Birnbaumer L, Ambudkar IS (1999) Cloning of Trp1β isoform from rat brain: immunodetection and localization of the endogenous Trp1 protein. Am J Physiol 276:C969-C979
88. 88. Sakura H, Ashcroft FM (1997) Identification of four trp1 gene variante murine pancreatic beta-cells. Diabetologia 40:528-532
89. 89. Bobanovic LK, Laine M, Petersen CCH, Bennett DL, Berridge MJ, Lipp P, Ripley SJ, Bootman MD (1999) Molecular cloning and immunolocalization of a novel vertebrate trp homologue from Xenopus. Biochem J 340:593-599
90. 2+ entry channel. Proc Natl Acad Sci USA 96:2060-2064
91. 91. Liman ER, Corey DP, Dulac C (1999) TRP2: a candidate transduction channel for mammalian pheromone sensory signaling. Proc Natl Acad Sci USA 96:5791-5796
92. 2+ entry. Cell 85: 661-671
93. 93. Zitt C, Obukhov AG, Strübing C, Zobel A, Kalkbrenner F, Lückhoff A, Schultz G (1997) Expression of TRPC3 in Chinese hamster ovary cells results in calcium-activated cation currents not related to store depletion. J Cell Biol 138:1333-1341
94. 94. Okada T, Inoue R, Yamazaki K, Maeda A, Kurosaki T, Yamakuni T, Tanaka I, Shimizu S, Ikenaka K, Imoto K, Mori Y (1999) Molecular and functional characterization of a novel mouse transient receptor potential protein homologue TRP7. J Biol Chem 274:27359-27370
95. q class of G protein. J Biol Chem 272:29672-29680
96. 96. Buess M, Engler O, Hirsch HH, Moroni C (1999) Search for oncogenic regulators in an autocrine tumor model using differential display PCR: identification of novel candidate genes including the calcium channel mtrp6. Oncogene 18:1487-1494
97. 97. Mizuno N, Kitayama S, Saishin Y, Shimada S, Morita K, Mitsuhata C, Kurihara H, Dohi T (1999) Molecular cloning and characterization of rat TRP homologues from brain. Brain Res Mol Brain Res 64:41-51
98. 98. Hofmann T, Obukhov AG, Schaefer M, Harteneck C, Gudermann T, Schultz G (1999) Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol. Nature 397:259-263
99. 99. Philipp S, Cavalie A, Freichel M, Wissenbach U, Zimmer S, Trost C, Marquart A, Murakami M, Flockerzi V (1996) A mammalian capacitive calcium entry channel homolgous to Drosophila TRP and TRPL. EMBO J 15:6166-6171
100. 2+) channel. Brain Res Mol Brain Res 43:259-266
101. 2+ channel from mouse brain. J Biol Chem 273:10279-10287
102. 102. Philipp S, Hambrecht J, Braslavski L, Schroth G, Freichel M, Murakami M, Cavalie A, Flockerzi V (1998) A novel capacitive calcium entry channel expressed in excitable cells. EMBO J 17:4274-4282
103. 103. Preuß KD, Nöller JK, Krause E, Göbel A, Schulz I (1997) Expression and characterization of a TRPL homolog from rat. Biochem Biophys Res Commun 240:167-172
104. 104. Groschner K, Hingel S, Lintschinger B, Balzer M, Romanin C, Zhu X, Schreibmayer W (1998) TRP proteins form store-operated cation channels in human vascular endothelial cells. FEBS Lett 437:101-106
105. 3 receptors and store-operated Htrp3 channels. Nature 396:478-482
106. 106. Sinkins WG, Estacion M, Schilling WP (1998) Functional expression of TRPC1: a human homologue of the Drosophila TRP channel. Biochem J 331:331-339
107. 2+ influx via human Trp3 stably expressed in human embryonic kidney (HEK)293 cells. J Biol Chem 273:133-142
108. 2+ influx in stably transfected HEK293 cells. FEBS Lett 422:333-338
109. 109. Kamouchi M, Philipp S, Flockerzi V, Wissenbach U, Mamin A, Raeymaekers L, Eggermont J, Droogmans G, Nilius B (1999) Properties of heterogenously expressed hTRP3 channels in bovine pulmonary artery endothelial cells. J Physiol (Lond) 518:345-358
110. 1-Adrenoreceptor activation of a non-selective cation current in rabbit portal vein by 1,2-diacyl-sn-glycerol J Physiol (Lond) 499:417-428
111. 111. Garcia RL, Schilling WP (1997) Differential expression of mammalian TRP homologues across tissues and cell lines. Biochem Biophys Res Commun 239:279-283
112. 112. Wissenbach U, Schroth G, Philipp S, Flockerzi V (1998) Structure and mRNA expression of a bovine TRP homologue related to mammalian TRP2 transcripts. FEBS Lett 429: 61-66
113. 2+ channel isoforms in mouse brain. Neuroreport 9:507-515