Maternal serum free β-hCG and PAPP-A in fetal sex chromosome defects in the first trimester

Prenatal Diagnosis

Volumn 20, Issue 5, 2000, Pages 390-394

  Spencer, Kevin ^a   Tul, Natasha ^b   Nicolaides, Kypros H ^b  

^a HAROLD WOOD HOSPITAL   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Biochemical screening; Nuchal translucency; Turner's syndrome

Indexed keywords

CHORIONIC GONADOTROPIN BETA SUBUNIT; PROTEIN A;

ADOLESCENT; ADULT; ALGORITHM; ANALYZER; ARTICLE; ASSAY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIAGNOSTIC TEST; FEMALE; FIRST TRIMESTER PREGNANCY; GONADOTROPIN BLOOD LEVEL; HUMAN; MAJOR CLINICAL STUDY; MATERNAL SERUM; NECK MUSCLE; PRENATAL DIAGNOSIS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SEX CHROMOSOME ABERRATION; TRISOMY 21; TURNER SYNDROME;

ADOLESCENT; ADULT; ALGORITHMS; CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN; CROWN-RUMP LENGTH; DOWN SYNDROME; FEMALE; GESTATIONAL AGE; HUMANS; MATERNAL AGE; MIDDLE AGED; NECK; PREGNANCY; PREGNANCY-ASSOCIATED PLASMA PROTEIN-A; PRENATAL DIAGNOSIS; RISK FACTORS; SEX CHROMOSOME ABERRATIONS; TURNER SYNDROME; ULTRASONOGRAPHY, PRENATAL;

EID: 0034062921     PISSN: 01973851     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0223(200005)20:5<390::AID-PD824>3.0.CO;2-B     Document Type: Article

References (16)

1. Christian SM, Koehn D, Pillay R, MacDougall A, Wilson RD. 2000. Parental decisions following prenatal diagnosis of sex chromosome aneuploidy: a trend over time. Prenat Diagn 20: 37-40.
2. Lambert-Messerlian GM, Saller DN, Tumber MB, French CA, Pelerson CJ, Canick JA. 1998. Second-trimester maternal serum inhibin A levels in fetal trisomy 18 and Turner syndrome with and without hydrops. Prenat Diagn 18: 1061-1067.
3. Lambert-Messerlian GM, Saller DN, Tumber MB, French CA, Peterson CJ, Canick JA. 1999. Second-trimester maternal serum progesterone levels in Turner syndrome with and without hydrops and in trisomy 18. Prenat Diagn 19: 476-479.
4. Laundon CH, Spencer K, Macri JN, Anderson RW, Buchanan PD. 1996. Free beta-hCG screening of hydropic and non-hydropic Turner syndrome pregnancies. Prenat Diagn 16: 853-856.
5. Neveux LM, Palomaki GE, Larivee DA, Knight GJ, Haddow JE. 1996. Refinements in managing maternal weight adjustment for interpreting prenatal screening results. Prenat Diagn 16: 1115-1119.
6. Nicolaides KH, Snijders RJM, Cuckle HS. 1998. Correct estimation of parameters for ultrasound nuchal translucency screening. Prenat Diagn 18: 519-521.
7. Saller DJ, Canick JA, Schwartz S, Blitzer MG. 1992. Multiple-marker screening in pregnancies with hydropic and nonhydropic Turner syndrome. Am J Obstet Gynecol 167: 1021-1024.
8. Sebire NJ, Snijders RJM, Brown R, Southall T, Nicolaides KH. 1998. Detection of sex chromosome abnormalities by nuchal translucency screening at 10 14 weeks. Prenat Diagn 18: 58-584.
9. Snijders RJM, Sebire NJ, Nicolaides KH. 1995. Maternal age and gestational age specific risk for chromosomal defects. Fetal Diagn Ther 10: 356-367.
10. Snijders RJM, Noble P, Sebire N, Souka A, Nicolaides KH, for the Fetal Medicine Foundation First-trimester Screening Group. 1998. UK multicentre project on assessment of risk of trisomy 21 by maternal age and fetal nuchal translucency thickness at 10 14 weeks of gestation. Lancet 351: 343-346.
11. Spencer K. 1999. One-stop clinic for assessment of risk for fetal abnormalities. Downs Screening News 6: 10.
12. Spencer K, Noble P, Snijders RJM, Nicolaides KH. 1997. First trimester urine free beta-hCG, beta core and total oestriol in pregnancies affected by Down's syndrome: implications for first trimester screening with nuchal translucency and serum free beta-hCG. Prenat Diagn 17: 525-538.
13. Spencer K, Souter V, Tul N, Snijders R, Nicoladies KH. 1999. A screening program for trisomy 21 at 10-14 weeks using fetal nuchal translucency, maternal serum free beta human chorionic gonadotropin and pregnancy associated plasma protein-A. Ultrasound Obstet Gynecol 13: 231-237.
14. Tul N, Spencer K, Noble P, Chan C, Nicolaides KH. 1999. Screening for trisomy 18 by fetal nuchal translucency and maternal serum free beta-hCG and PAPP-A at 10-14 weeks of gestation. Prenat Diagn 19: 1035-1042.
15. Wenstrom KD, Williamson RA, Grant S. 1994. Detection of fetal Turner syndrome with multiple marker screening. Am J Obstet Gynecol 170: 570-573.
16. Wenstrom KD, Boots LR, Cosper PC. 1996. Multiple marker screening test: identification of fetal cystic hygroma, hydrops and sex chromosome aneuploidy. J Matern Fetal Med 5: 31-35.