Antibodies against the Plasmodium falciparum receptor binding domain of EBA-175 block invasion pathways that do not involve sialic acids

Infection and Immunity

Volumn 68, Issue 4, 2000, Pages 1964-1966

  Narum, David L ^a   Haynes, J David ^b,c   Fuhrmann, Steven ^a   Moch, Kathy ^d   Liang, Hong ^a   Hoffman, Stephen L ^c   Sim, B Kim Lee ^a  

^a ENTREMED INC   (United States)

^b WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

^c NAVAL MEDICAL RESEARCH CENTER   (United States)

^d UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN G; MALARIA VACCINE; SIALIC ACID;

ARTICLE; CELL INVASION; CONTROLLED STUDY; GROWTH INHIBITION; HUMAN; HUMAN CELL; MEROZOITE; NONHUMAN; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PURIFICATION; RECEPTOR BINDING; STRAIN DIFFERENCE;

ANIMALS; ANTIBODIES, PROTOZOAN; ANTIGENS, PROTOZOAN; ANTIGENS, SURFACE; CARRIER PROTEINS; CELL DIVISION; ERYTHROCYTES; FLOW CYTOMETRY; HUMANS; IMMUNOGLOBULIN G; N-ACETYLNEURAMINIC ACID; NEURAMINIDASE; PLASMODIUM FALCIPARUM; PROTOZOAN PROTEINS; SPECIES SPECIFICITY; TRYPSIN;

EID: 0034062858     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.68.4.1964-1966.2000     Document Type: Article

References (16)

1. Adams, J. H., D. E. Hudson, M. Torii, G. E. Ward, T. E. Wellems, M. Aikawa, and L. H. Miller. 1990. The Duffy receptor family of Plasmodium knowlesi is located within the micronemes of invasive malaria merozoites. Cell 63:141-153.
2. Adams, J. H., B. K. Sim, S. A. Dolan, X. Fang, D. C. Kaslow, and L. H. Miller. 1992. A family of erythrocyte binding proteins of malaria parasites. Proc. Natl. Acad. Sci. USA 89:7085-7089.
3. Breuer, W. V., H. Ginsburg, and Z. I. Cabantchik. 1983. An assay of malaria parasite invasion into human erythrocytes. The effects of chemical and enzymatic modification of erythrocyte membrane components. Biochim. Biophys. Acta 755:263-271.
4. Camus, D., and T. J. Hadley. 1985. A Plasmodium falciparum antigen that binds to host erythrocytes and merozoites. Science 230:553-556.
5. Dolan, S. A., L. H. Miller, and T. E. Wellems. 1990. Evidence for a switching mechanism in the invasion of erythrocytes by Plasmodium falciparum. J. Clin. Investig. 86:618-624.
6. Dolan, S. A., J. L. Proctor, D. W. Alling, Y. Okubo, T. E. Wellems, and L. H. Miller. 1994. Glycophorin B as an EBA-175 independent Plasmodium falciparum receptor of human erythrocytes. Mol. Biochem. Parasitol. 64:55-63.
7. Hadley, T. J., F. W. Klotz, G. Pasvol, J. D. Haynes, M. H. McGinniss, Y. Okubo, and L. H. Miller. 1987. Falciparum malaria parasites invade erythrocytes that lack glycophorin A and B (MkMk). Strain differences indicate receptor heterogeneity and two pathways for invasion. J. Clin. Investig. 80:1190-1193.
8. Kwiatkowski, D. 1989. Febrile temperatures can synchronize the growth of Plasmodium falciparum in vitro. J. Exp. Med. 169:357-361.
9. Liang, H., and B. K. Sim. 1997. Conservation of structure and function of the erythrocyte-binding domain of Plasmodium falciparum EBA-175. Mol. Biochem. Parasitol. 84:241-245.
10. Mitchell, G. H., T. J. Hadley, M. H. McGinniss, F. W. Klotz, and L. H. Miller. 1986. Invasion of erythrocytes by Plasmodium falciparum malaria parasites: evidence for receptor heterogeneity and two receptors. Blood 67:1519-1521.
11. Orlandi, P. A., B. K. Sim, J. D. Chulay, and J. D. Haynes. 1990. Characterization of the 175-kilodalton erythrocyte binding antigen of Plasmodium falciparum. Mol. Biochem. Parasitol. 40:285-294.
12. Shi, Y. P., V. Udhayakumar, A. J. Oloo, B. L. Nahlen, and A. A. Lal. 1999. Differential effect and interaction of monocytes, hyperimmune sera, and immunoglobulin G on the growth of asexual stage Plasmodium falciparum parasites. Am. J. Trop. Med. Hyg. 60:135-141.
13. Sim, B. K., P. A. Orlandi, J. D. Haynes, F. W. Klotz, J. M. Carter, D. Camus, M. E. Zegans, and J. D. Chulay. 1990. Primary structure of the 175K Plasmodium falciparum erythrocyte binding antigen and identification of a peptide which elicits antibodies that inhibit malaria merozoite invasion. J. Cell. Biol. 111:1877-1884.
14. Sim, B. K. L., C. E. Chitnis, K. Wasniowska, T. J. Hadley, and L. H. Miller. 1994. Receptor and ligand domains for invasion of erythrocytes by Plasmodium falciparum. Science 264:1941-1944.
15. Trager, W., and J. B. Jensen. 1976. Human malaria parasites in continuous culture. Science 193:673-675.
16. Vernes, A., J. D. Haynes, P. Tapchaisri, J. L. Williams, E. Dutoit, and C. L. Diggs. 1984. Plasmodium falciparum strain-specific human antibody inhibits merozoite invasion of erythrocytes. Am. J. Trop. Med. Hyg. 33:197-203.