메뉴 건너뛰기




Volumn 267, Issue 6, 2000, Pages 1878-1885

Pig MAP/ITIH4 and haptoglobin are interleukin-6-dependent acute-phase plasma proteins in porcine primary cultured hepatocytes

Author keywords

Acute phase proteins; Cytokines; Hepatocytes; Inter trypsin inhibitor (I I); ITIH4

Indexed keywords

ALBUMIN; BACTERIUM LIPOPOLYSACCHARIDE; HAPTOGLOBIN; INTERLEUKIN 1; INTERLEUKIN 6; PLASMA PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 0034062303     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.2000.01195.x     Document Type: Article
Times cited : (66)

References (51)
  • 1
    • 0020000298 scopus 로고
    • The phenomenon of the acute phase response
    • 1. Kushner, I. (1982) The phenomenon of the acute phase response. Ann. N.Y. Acad. Sci. 389, 39-48.
    • (1982) Ann. N.Y. Acad. Sci. , vol.389 , pp. 39-48
    • Kushner, I.1
  • 3
    • 0028095919 scopus 로고
    • The acute phase response
    • 3. Baumann, H. & Gauldie, J. (1994) The acute phase response. Immunol. Today 15, 74-80.
    • (1994) Immunol. Today , vol.15 , pp. 74-80
    • Baumann, H.1    Gauldie, J.2
  • 4
    • 0030823183 scopus 로고    scopus 로고
    • IL-6 and APPs: Anti-inflammatory and immunosuppressive mediators
    • 4. Tilg, H., Dinarello, C.A. & Mier, J.W. (1997) IL-6 and APPs: anti-inflammatory and immunosuppressive mediators. Immunol. Today 18, 428-432.
    • (1997) Immunol. Today , vol.18 , pp. 428-432
    • Tilg, H.1    Dinarello, C.A.2    Mier, J.W.3
  • 5
    • 0025190892 scopus 로고
    • Interleukìn-6 and the acute phase response
    • 5. Heinrich, P.C., Castell, J.V. & Andus, T. (1990) Interleukìn-6 and the acute phase response. Biochem. J. 265, 621-636.
    • (1990) Biochem. J. , vol.265 , pp. 621-636
    • Heinrich, P.C.1    Castell, J.V.2    Andus, T.3
  • 7
    • 0029890967 scopus 로고    scopus 로고
    • The acute phase response of acid soluble glycoprotein, α-1-acid glycoprotein, ceruloplasmin, haptoglobin and C-reactive protein, in the pig
    • 7. Eckersall, P.D., Saini, P.K. & McComb, C. (1996) The acute phase response of acid soluble glycoprotein, α-1-acid glycoprotein, ceruloplasmin, haptoglobin and C-reactive protein, in the pig. Vet. Immunol. Immunopathol. 51, 377-385.
    • (1996) Vet. Immunol. Immunopathol. , vol.51 , pp. 377-385
    • Eckersall, P.D.1    Saini, P.K.2    McComb, C.3
  • 8
    • 0030185416 scopus 로고    scopus 로고
    • Serum haptoglobin concentration in growing swine after intranasal challenge with Bordetella bronchiseptica and Pasteurella multicocica type D
    • 8. Francisco, C.J., Shryock, T.R., Bane, D.P. & Unverzagt, L. (1996) Serum haptoglobin concentration in growing swine after intranasal challenge with Bordetella bronchiseptica and Pasteurella multicocica type D. Can. J. Vet. Res. 60, 222-227.
    • (1996) Can. J. Vet. Res. , vol.60 , pp. 222-227
    • Francisco, C.J.1    Shryock, T.R.2    Bane, D.P.3    Unverzagt, L.4
  • 9
    • 0027032013 scopus 로고
    • Serum haptoglobin concentration in swine naturally or experimentally infected with Actinobacillus pleuropneumoniae
    • 9. Hall, W.F., Eurell, T.E., Hansen, R.D. & Herr, L.G. (1992) Serum haptoglobin concentration in swine naturally or experimentally infected with Actinobacillus pleuropneumoniae. J. Am. Vet. Med. An. 201, 1730-1733.
    • (1992) J. Am. Vet. Med. An. , vol.201 , pp. 1730-1733
    • Hall, W.F.1    Eurell, T.E.2    Hansen, R.D.3    Herr, L.G.4
  • 10
    • 0031899479 scopus 로고    scopus 로고
    • The porcine acute-phase response to infection with Actinobacillus pleuropneumoniae. Haptoglobin, C-reactive protein and major acute-phase protein are sensitive indicators of ìnfection
    • 10. Heegaard, P.M.H., Klausen, J., Nielsen, J.P., González-Ramón, N., Piñeiro, M., Lampreave, F. & Alava, M.A. (1998) The porcine acute-phase response to infection with Actinobacillus pleuropneumoniae. Haptoglobin, C-reactive protein and major acute-phase protein are sensitive indicators of ìnfection. Comp. Biochem. Physiol. 119B, 365-373.
    • (1998) Comp. Biochem. Physiol. , vol.119 B , pp. 365-373
    • Heegaard, P.M.H.1    Klausen, J.2    Nielsen, J.P.3    González-Ramón, N.4    Piñeiro, M.5    Lampreave, F.6    Alava, M.A.7
  • 11
    • 84983947155 scopus 로고
    • C-reactive protein, a characteristic feature of health control in swine
    • 11. Bürger, W., Fennert, E.-M., Pohle, M. & Wesemeier, H. (1992) C-reactive protein, a characteristic feature of health control in swine. J. Vet. Med. A 39, 635-638.
    • (1992) J. Vet. Med. A , vol.39 , pp. 635-638
    • Bürger, W.1    Fennert, E.-M.2    Pohle, M.3    Wesemeier, H.4
  • 12
    • 0026487941 scopus 로고
    • Serum haptoglobin concentration as an indicator of weight gain in pigs
    • 12. Eurell, T.E., Bane, D.P., Hall, W.F. & Schaeffer, D.J. (1992) Serum haptoglobin concentration as an indicator of weight gain in pigs. Can. J. Vet. Res. 56, 6-9.
    • (1992) Can. J. Vet. Res. , vol.56 , pp. 6-9
    • Eurell, T.E.1    Bane, D.P.2    Hall, W.F.3    Schaeffer, D.J.4
  • 14
    • 0028982526 scopus 로고
    • cDNA and deduced amino acid sequence of human PK-120, a plasma kallikrein-sensitive glycoprotein
    • 14. Nishimura, H., Kakizaki, I., Muta, T., Sasaki, N., Pu, X.P., Yamashita, T. & Nagasawa, S. (1995) cDNA and deduced amino acid sequence of human PK-120, a plasma kallikrein-sensitive glycoprotein. FEBS Lett. 357, 207-211.
    • (1995) FEBS Lett. , vol.357 , pp. 207-211
    • Nishimura, H.1    Kakizaki, I.2    Muta, T.3    Sasaki, N.4    Pu, X.P.5    Yamashita, T.6    Nagasawa, S.7
  • 15
    • 0028872421 scopus 로고
    • Cloning and characterization of cDNA for inter-α-trypsin inhibitor family heavy chain-related protein (IHRP), a novel human plasma glycoprotein
    • 15. Saguchi, K., Tobe, T., Hashimoto, K., Sano, Y., Nakano, Y., Miura, N.-H. & Tomita, M. (1995) Cloning and characterization of cDNA for inter-α-trypsin inhibitor family heavy chain-related protein (IHRP), a novel human plasma glycoprotein. J. Biochem. 117, 14-18.
    • (1995) J. Biochem. , vol.117 , pp. 14-18
    • Saguchi, K.1    Tobe, T.2    Hashimoto, K.3    Sano, Y.4    Nakano, Y.5    Miura, N.-H.6    Tomita, M.7
  • 16
    • 0029669926 scopus 로고    scopus 로고
    • The inter-α-inhibitor family: From structure to regulation
    • 16. Salier, J.P., Rouet, P., Raguenez, G. & Daveau, M. (1996) The inter-α-inhibitor family: from structure to regulation. Biochem. J. 315, 1-9.
    • (1996) Biochem. J. , vol.315 , pp. 1-9
    • Salier, J.P.1    Rouet, P.2    Raguenez, G.3    Daveau, M.4
  • 17
    • 0029998668 scopus 로고    scopus 로고
    • Primary structure of the pig homologue of human IHRP: Inter α-trypsin inhibitor family heavy chain-related protein
    • 17. Hashimoto, K., Tobe, T., Sumiya, J., Sano, Y., Choi-Miura, N.H., Ozawa, A., Yasue, H. & Tomita, M. (1996) Primary structure of the pig homologue of human IHRP: inter α-trypsin inhibitor family heavy chain-related protein. J. Biochem. Tokyo 119, 577-584.
    • (1996) J. Biochem. Tokyo , vol.119 , pp. 577-584
    • Hashimoto, K.1    Tobe, T.2    Sumiya, J.3    Sano, Y.4    Choi-Miura, N.H.5    Ozawa, A.6    Yasue, H.7    Tomita, M.8
  • 18
    • 0032512577 scopus 로고    scopus 로고
    • The H4P heavy chain of ìnter-α-inhibitor family largely differs in the structure and synthesis of its prolinerich region from rat to human
    • 18. Soury, E., Olivier, E., Daveau, M., Hiron, M., Claeyssens, S., Risler, J.L. & Salier, J.P. (1998) The H4P heavy chain of ìnter-α-inhibitor family largely differs in the structure and synthesis of its prolinerich region from rat to human. Biochem. Biophys. Res. Comm. 243, 522-530.
    • (1998) Biochem. Biophys. Res. Comm. , vol.243 , pp. 522-530
    • Soury, E.1    Olivier, E.2    Daveau, M.3    Hiron, M.4    Claeyssens, S.5    Risler, J.L.6    Salier, J.P.7
  • 19
    • 0032521592 scopus 로고    scopus 로고
    • Inter-α-trypsin inhibitor proteoglycan family. A group of proteins binding and stabilizing the extracellular matrix
    • 19. Bost, F., Diarra-Mehrphour, M. & Martin, J.P. (1998) Inter-α-trypsin inhibitor proteoglycan family. A group of proteins binding and stabilizing the extracellular matrix. Eur. J. Biochem. 252, 339-346.
    • (1998) Eur. J. Biochem. , vol.252 , pp. 339-346
    • Bost, F.1    Diarra-Mehrphour, M.2    Martin, J.P.3
  • 21
    • 0344132074 scopus 로고    scopus 로고
    • ITIH4 serum concentration increases during acute phase processes in human patients and is up-regulated by interleukin-6 in hepatocarcinoma HepG2 cells
    • 21. Piñeiro, M., Alava, M.A., González-Ramón, N., Osada, J., Lasierra, P., Larrad, L., Piñeiro, P. & Lampreave, F. (1999) ITIH4 serum concentration increases during acute phase processes in human patients and is up-regulated by interleukin-6 in hepatocarcinoma HepG2 cells. Biochim. Biophys. Res. Comm. 263, 224-229.
    • (1999) Biochim. Biophys. Res. Comm. , vol.263 , pp. 224-229
    • Piñeiro, M.1    Alava, M.A.2    González-Ramón, N.3    Osada, J.4    Lasierra, P.5    Larrad, L.6    Piñeiro, P.7    Lampreave, F.8
  • 22
    • 0029962068 scopus 로고    scopus 로고
    • Suppression of cytochrome P450- and UDP glucuronosyl transferase-dependent enzyme activities by proinflammatory cytokines and possible role of nitric oxide in primary cultures of pig hepatocytes
    • 22. Monshouwer, M., Witkamp, R.F., Nujmeijer, S.M., Van-Amsterdam, J.G. & Van-Miert, A.S. (1996) Suppression of cytochrome P450- and UDP glucuronosyl transferase-dependent enzyme activities by proinflammatory cytokines and possible role of nitric oxide in primary cultures of pig hepatocytes. Tox. Appl. Pharmacol. 137, 237-244.
    • (1996) Tox. Appl. Pharmacol. , vol.137 , pp. 237-244
    • Monshouwer, M.1    Witkamp, R.F.2    Nujmeijer, S.M.3    Van-Amsterdam, J.G.4    Van-Miert, A.S.5
  • 24
    • 0024828121 scopus 로고
    • Quantitation of mRNA by the polymerase chain reaction
    • 24. Wang, A.M., Doyle, M.V. & Mark, D.F. (1989) Quantitation of mRNA by the polymerase chain reaction. Proc. Natl Acad. Sci. USA 66, 9717-9721.
    • (1989) Proc. Natl Acad. Sci. USA , vol.66 , pp. 9717-9721
    • Wang, A.M.1    Doyle, M.V.2    Mark, D.F.3
  • 25
    • 0021760884 scopus 로고
    • Characterization of human haptoglobin cDNAs coding for α 2FS beta and α 1S beta variants
    • 25. van der Straten, A., Herzog, A., Cabezón, T. & Bollen, A. (1984) Characterization of human haptoglobin cDNAs coding for α 2FS beta and α 1S beta variants. FEBS Lett. 168, 103-107.
    • (1984) FEBS Lett. , vol.168 , pp. 103-107
    • Van Der Straten, A.1    Herzog, A.2    Cabezón, T.3    Bollen, A.4
  • 27
    • 0014447778 scopus 로고
    • Coupling of enzymes to proteins with glutar-aldehyde. Use of the conjugates for the detection of antigen and antibodies
    • 27. Avrameas, S. (1969) Coupling of enzymes to proteins with glutar-aldehyde. Use of the conjugates for the detection of antigen and antibodies. Immunochem. 6, 43-66.
    • (1969) Immunochem. , vol.6 , pp. 43-66
    • Avrameas, S.1
  • 28
    • 0024540278 scopus 로고
    • Stimulation of hepatic acute phase response by cytokines and glucocorticoids
    • 28. Baumann, P.K.R., Marinkovic, S., Wong, K.-A. & Jahreis, G.P. (1989) Stimulation of hepatic acute phase response by cytokines and glucocorticoids. Ann. N.Y. Acad. Sci. 557, 280-296.
    • (1989) Ann. N.Y. Acad. Sci. , vol.557 , pp. 280-296
    • Baumann, P.K.R.1    Marinkovic, S.2    Wong, K.-A.3    Jahreis, G.P.4
  • 29
    • 0023880660 scopus 로고
    • Action of recombinant human interleukin-6, interleukin-1-beta and tumor necrosis factor α on the mRNA induction of acute-phase proteins
    • 29. Andus, T., Geiger, T., Hirano, T., Kishimoto, T. & Heinrich, P.C. (1988) Action of recombinant human interleukin-6, interleukin-1-beta and tumor necrosis factor α on the mRNA induction of acute-phase proteins. Eur. J. Immunol. 18, 739-746.
    • (1988) Eur. J. Immunol. , vol.18 , pp. 739-746
    • Andus, T.1    Geiger, T.2    Hirano, T.3    Kishimoto, T.4    Heinrich, P.C.5
  • 30
    • 0024603761 scopus 로고
    • Interleukin-1 and its biologically related cytokines
    • 30. Dinarello, C.A. (1989) Interleukin-1 and its biologically related cytokines. Adv. Immunol. 44, 153-205.
    • (1989) Adv. Immunol. , vol.44 , pp. 153-205
    • Dinarello, C.A.1
  • 31
    • 0021745769 scopus 로고
    • The acute-phase response of cultured rat hepatocytes. System characterization and the effect of human cytokines
    • 31. Koj, A., Gauldie, J., Regoeczi, E., Sauder, D.N. & Sweeney, G.D. (1984) The acute-phase response of cultured rat hepatocytes. System characterization and the effect of human cytokines. Biochem. J. 224, 505-514.
    • (1984) Biochem. J. , vol.224 , pp. 505-514
    • Koj, A.1    Gauldie, J.2    Regoeczi, E.3    Sauder, D.N.4    Sweeney, G.D.5
  • 32
    • 0032168152 scopus 로고    scopus 로고
    • Interleukin-6-type cytokine signalling through the gp130/JAK/STAT pathway
    • 32. Heinrich, P.C., Behrmann, I., Muller-Newen, G., Schaper, F. & Graeve, L. (1998) Interleukin-6-type cytokine signalling through the gp130/JAK/STAT pathway. Biochem. J. 334, 279-314.
    • (1998) Biochem. J. , vol.334 , pp. 279-314
    • Heinrich, P.C.1    Behrmann, I.2    Muller-Newen, G.3    Schaper, F.4    Graeve, L.5
  • 34
    • 0032928969 scopus 로고    scopus 로고
    • Fatty acid desaturation: Effect of α-fetoprotein on α-linolenic acid conversion by fetal rat hepatocytes
    • 34. Alava, M.A., Iturralde, M., Gonzalez, B. & Piñeiro, A. (1999) Fatty acid desaturation: effect of α-fetoprotein on α-linolenic acid conversion by fetal rat hepatocytes. Prost. Leukotr. Ess. Fat. Ac. 60, 209-215.
    • (1999) Prost. Leukotr. Ess. Fat. Ac. , vol.60 , pp. 209-215
    • Alava, M.A.1    Iturralde, M.2    Gonzalez, B.3    Piñeiro, A.4
  • 35
    • 0344882588 scopus 로고    scopus 로고
    • Structural characterization of inter-α-inhibitor. Evidence for an extended shape
    • 35. Blom, A.M., Mörgelin, M., Öyen, M., Jarvet, J. & Fries, E. (1999) Structural characterization of inter-α-inhibitor. Evidence for an extended shape. J. Biol. Chem. 274, 298-304.
    • (1999) J. Biol. Chem. , vol.274 , pp. 298-304
    • Blom, A.M.1    Mörgelin, M.2    Öyen, M.3    Jarvet, J.4    Fries, E.5
  • 36
    • 0024508326 scopus 로고
    • Isolation and characterization of a novel plasma protein which binds to activated C4 of the classical complement pathway
    • 36. Hammer, C.H., Jacobs, R.M. & Frank, M.M. (1989) Isolation and characterization of a novel plasma protein which binds to activated C4 of the classical complement pathway. J. Biol. Chem. 264, 2283-2291.
    • (1989) J. Biol. Chem. , vol.264 , pp. 2283-2291
    • Hammer, C.H.1    Jacobs, R.M.2    Frank, M.M.3
  • 37
    • 0029050756 scopus 로고
    • Purification and characterization of PK-120, a novel substrate for plasma kallikrein from guinea pig plasma
    • 37. Pu, X.P. & Nagasawa, S. (1995) Purification and characterization of PK-120, a novel substrate for plasma kallikrein from guinea pig plasma. Biol. Pharm. Bull. 18, 837-841.
    • (1995) Biol. Pharm. Bull. , vol.18 , pp. 837-841
    • Pu, X.P.1    Nagasawa, S.2
  • 38
    • 0028171422 scopus 로고
    • Proteins of the inter-α-trypsin inhibitor family stabilize the cumulus extracellular matrix through their direct binding with hyaluronic acid
    • 38. Chen, L., Mao, S.J.T., McLean, L.R., Powers, R.W. & Larsen, W.J. (1994) Proteins of the inter-α-trypsin inhibitor family stabilize the cumulus extracellular matrix through their direct binding with hyaluronic acid. J. Biol. Chem. 269, 28282-28287.
    • (1994) J. Biol. Chem. , vol.269 , pp. 28282-28287
    • Chen, L.1    Mao, S.J.T.2    McLean, L.R.3    Powers, R.W.4    Larsen, W.J.5
  • 39
    • 33845992657 scopus 로고    scopus 로고
    • Expression of an inter-α-trypsin inhibitor heavy chain-like protein in the pig endometrium during the oestrous cycle and early pregnancy
    • 39. Geiser, R.D., Yelich, J.V., Pratt, T. & Pomp, D. (1998) Expression of an inter-α-trypsin inhibitor heavy chain-like protein in the pig endometrium during the oestrous cycle and early pregnancy. J. Reprod. Fertility 114, 35-43.
    • (1998) J. Reprod. Fertility , vol.114 , pp. 35-43
    • Geiser, R.D.1    Yelich, J.V.2    Pratt, T.3    Pomp, D.4
  • 40
    • 0025182686 scopus 로고
    • Molecular biology of circulatory shock. Part II. Expression of four groups of hepatic genes is enhanced after resuscitation from cardiogenic shock
    • 40. Buchman, T.G., Cabin, D.E., Vickers, S., Deutschman, C.S., Delgado, E., Sussman, M.M. & Bulkley, G.B. (1990) Molecular biology of circulatory shock. Part II. Expression of four groups of hepatic genes is enhanced after resuscitation from cardiogenic shock. Surgery 108, 560-566.
    • (1990) Surgery , vol.108 , pp. 560-566
    • Buchman, T.G.1    Cabin, D.E.2    Vickers, S.3    Deutschman, C.S.4    Delgado, E.5    Sussman, M.M.6    Bulkley, G.B.7
  • 41
    • 0029095395 scopus 로고
    • Hepatic heat shock and acute-phase gene expression are induced simultaneously after celiotomy in the anesthetized pig
    • 41. Pannen, B.H.J., Maeda, K., Ayuse, T., Brienza, N., Revelly, J.P., Robotham, J.L. & Buchman, T.G. (1995) Hepatic heat shock and acute-phase gene expression are induced simultaneously after celiotomy in the anesthetized pig. Anesthesiology 83, 850-859.
    • (1995) Anesthesiology , vol.83 , pp. 850-859
    • Pannen, B.H.J.1    Maeda, K.2    Ayuse, T.3    Brienza, N.4    Revelly, J.P.5    Robotham, J.L.6    Buchman, T.G.7
  • 42
    • 0031017317 scopus 로고    scopus 로고
    • Purification and characterization of pig inter-α-inhibitor and its constitutive heavy chains
    • 42. Carrette, O., Mizon, C., Sautiére, P., Sesboüe, R. & Mizon, J. (1997) Purification and characterization of pig inter-α-inhibitor and its constitutive heavy chains. Biochim. Biophys. Acta 1338, 21-30.
    • (1997) Biochim. Biophys. Acta , vol.1338 , pp. 21-30
    • Carrette, O.1    Mizon, C.2    Sautiére, P.3    Sesboüe, R.4    Mizon, J.5
  • 43
    • 0027208218 scopus 로고
    • Human inter-α-inhibitory family in inflammation: Simultaneous synthesis of positive and negative acute-phase proteins
    • 43. Daveau, M., Rouet, P., Scotte, M., Faye, L., Hiron, M., Lebreton, J.P. & Salier, J.P. (1993) Human inter-α-inhibitory family in inflammation: simultaneous synthesis of positive and negative acute-phase proteins. Biochem. J. 292, 485-492.
    • (1993) Biochem. J. , vol.292 , pp. 485-492
    • Daveau, M.1    Rouet, P.2    Scotte, M.3    Faye, L.4    Hiron, M.5    Lebreton, J.P.6    Salier, J.P.7
  • 46
    • 0023213963 scopus 로고
    • Distinct sets of acute phase plasma proteins are stimulated by separate human hepatocyte-stimulating factors and monokines in rat hepatoma cells
    • 46. Baumann, H., Onorato, V., Gauldie, J. & Jahreis, G.P. (1987) Distinct sets of acute phase plasma proteins are stimulated by separate human hepatocyte-stimulating factors and monokines in rat hepatoma cells. J. Biol. Chem. 262, 9756-9768.
    • (1987) J. Biol. Chem. , vol.262 , pp. 9756-9768
    • Baumann, H.1    Onorato, V.2    Gauldie, J.3    Jahreis, G.P.4
  • 47
    • 0029279599 scopus 로고
    • Stimulation of haptoglobin synthesis by interleukin-6 and tumor necrosis factor but not by interleukin-1 in bovine primary cultured hepatocytes
    • 47. Nakagawa-Tosa, N., Morimatsu, M., Kawasaki, M., Nakatsuji, H., Syuto, B. & Saito, M. (1995) Stimulation of haptoglobin synthesis by interleukin-6 and tumor necrosis factor but not by interleukin-1 in bovine primary cultured hepatocytes. J. Vet. Med. Sci. 57, 219-223.
    • (1995) J. Vet. Med. Sci. , vol.57 , pp. 219-223
    • Nakagawa-Tosa, N.1    Morimatsu, M.2    Kawasaki, M.3    Nakatsuji, H.4    Syuto, B.5    Saito, M.6
  • 48
    • 0023887261 scopus 로고
    • Recombinant human interleukin-6 (IL-6/ BSF-2HSF) regulates the synthesis of acute phase proteins in human hepatocytes
    • 48. Castell, J.V., Gómez-Lechón, M.J., David, M., Hirano, T., Kishimoto, T. & Heinrich, P.C. (1988) Recombinant human interleukin-6 (IL-6/ BSF-2/HSF) regulates the synthesis of acute phase proteins in human hepatocytes. FEBS Lett. 232, 347-350.
    • (1988) FEBS Lett. , vol.232 , pp. 347-350
    • Castell, J.V.1    Gómez-Lechón, M.J.2    David, M.3    Hirano, T.4    Kishimoto, T.5    Heinrich, P.C.6
  • 49
    • 0025765623 scopus 로고
    • Effects of cytokine combinations on acute phase protein production in two human hepatoma cell lines
    • 49. Mackiewicz, A., Speroff, T., Ganapathi, M.K. & Kushner, I. (1991) Effects of cytokine combinations on acute phase protein production in two human hepatoma cell lines. J. Immunol. 146, 3032-3037.
    • (1991) J. Immunol. , vol.146 , pp. 3032-3037
    • Mackiewicz, A.1    Speroff, T.2    Ganapathi, M.K.3    Kushner, I.4
  • 50
    • 0029023496 scopus 로고
    • Porcine hepatocytes fron slaugtherhouse organs an unlimited resource for bioartificial liver devices
    • 50. Koebe, H.G., Pahernik, S.A., Sproede, M., Thasler, W.E. & Schildberg, F.W. (1995) Porcine hepatocytes fron slaugtherhouse organs an unlimited resource for bioartificial liver devices. ASAIO J. 41, 189-193.
    • (1995) ASAIO J. , vol.41 , pp. 189-193
    • Koebe, H.G.1    Pahernik, S.A.2    Sproede, M.3    Thasler, W.E.4    Schildberg, F.W.5
  • 51
    • 0029064875 scopus 로고
    • Functional activity of isolated pig hepatocytes attached to different extracellular matrix substrates. Implication for application of pig hepatocytes in bioartificial liver
    • 51. Velde, A.A., Ladiges, N.C., Flendrig, L.M. & Chamuleau, R.A. (1995) Functional activity of isolated pig hepatocytes attached to different extracellular matrix substrates. Implication for application of pig hepatocytes in bioartificial liver. J. Hepatol. 23, 184-192.
    • (1995) J. Hepatol. , vol.23 , pp. 184-192
    • Velde, A.A.1    Ladiges, N.C.2    Flendrig, L.M.3    Chamuleau, R.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.