The limbic cortex in schizophrenia: Focus on the anterior cingulate

Brain Research Reviews

Volumn 31, Issue 2-3, 2000, Pages 364-370

  Tamminga, Carol A ^a   Vogel, Michael ^a   Gao, Xue Min ^a   Lahti, Adrienne C ^a   Holcomb, Henry H ^a  

^a MARYLAND PSYCHIATRIC RESEARCH CENTER   (United States)

Author keywords

Anterior cingulate; Glutamate; Haloperidol; Ketamine; Limbic cortex; nCBF; NMDA

Indexed keywords

DIZOCILPINE; GLUTAMATE RECEPTOR; GLUTAMIC ACID; HALOPERIDOL; KETAMINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PHENCYCLIDINE;

ANATOMY; ANIMAL MODEL; BRAIN METABOLISM; CINGULATE GYRUS; CONFERENCE PAPER; GLUCOSE METABOLISM; HUMAN; LIMBIC CORTEX; NEUROCHEMISTRY; NONHUMAN; PRIORITY JOURNAL; SCHIZOPHRENIA;

ANIMALS; GYRUS CINGULI; HUMANS; SCHIZOPHRENIA;

EID: 0034062079     PISSN: 01650173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-0173(99)00053-3     Document Type: Conference Paper

References (67)

1. Akbarian S., Vinuela A., Kim J.J., Potkin S.G., Bunney W.E. Jr., Jones E.G. Distorted distribution of nicotinamide-adenine dinucleotide phosphate-diaphorase neurons in temporal lobe of schizophrenics implies anomalous cortical development. Arch. Gen. Psychiatry. 50:1993;178-187.
2. Altschuler L.L., Conrad A., Kovelman J., Scheibel A. Hippocampal pyramidal cell orientation in schizophrenia: A controlled neurohistology study of the Yakovlev collection. Arch. Gen. Psychiatry. 44:1987;1094-1098.
3. Arnold S.E., Hyman B.T., Van Hoesen G.W., Damasio A.R. Some cytoarchitectural abnormalities of the entorhinal cortex in schizophrenia. Arch. Gen. Psychiatry. 48:1991;625-632.
4. Baisden R.H., Woodruff M.L., Hoover D.B. Cholinergic and non-cholinergic septohippocampal projections: a double label horseradish peroxydase-acetylcholinersterase study in the rabbit. Brain Res. 290:1984;146-151.
5. Benes F.M., Davidson B., Bird E.D. Quantitative cytoarchitectural studies of the cerebral cortex of schizophrenics. Arch. Gen. Psychiatry. 43:1986;31-35.
6. Benes F.M., Bird E.D. An analysis of the arrangement of neurons in the cingulate cortex of schizophrenic patients. Arch. Gen. Psychiatry. 44:1987;608-616.
7. Benes F.M., Sorensen I., Bird E.D. Reduced neuronal size in posterior hippocampus of schizophrenic patients. Schizophr. Bull. 4(17):1991;597-608.
8. Benes F.M., McSparren J., Bird E.D., SanGiovanni J.P., Vincent S.L. Deficits in small interneurons in prefrontal and cingulate cortex of schizophrenic and schizoaffective patients. Arch. Gen. Psychiatry. 48:1991;996-1001.
9. Benes F.M., Vincent S.L., Alsterberg G., Bird E.D., SanGiovanni J.P. Increased GABA-A receptor binding in superficial layers of cingulate cortex in schizophrenics. J. Neurosci. 12:1992;924-929.
10. Blackstad T.W., Brink K., Hem J., Jeune B. Distribution of hippocampal mossy fibers in the rat. An experimental study with silver impregnation methods. J. Comp. Neurol. 138:1970;433-450.
11. Bogerts B., Meertz E., Schonfeld-Bausch R. Basal ganglia and limbic system pathology in schizophrenia. Arch. Gen. Psychiatry. 42:1985;784-791.
12. Brown R., Colter N., Corsellis J., Crow T.J., Frith C.D., Jagoe R., Johnstone E.C., Marsh L. Postmortem evidence of structural brain changes in schizophrenia, differences in brain weight, temporal horn area and parahippocampal gyrus compared with affective disorder. Arch. Gen. Psychiatry. 43:1986;36-42.
13. Bruton C.J., Crow T.J., Frith C.D., Johnstone E.C., Owens D.G.C., Roberts G.W. Schizophrenia and the brain: a prospective clinico-neuropathological study. Psychol. Med. 20:1990;285-304.
14. Bunney B.G., Potkin S.G., Bunney W.E. Neuropathological studies of brain tissue in schizophrenia. J. Psychiat. Res. 31:1997;159-174.
15. Cabeza R., Nyberg L. Imaging cognition: an empirical review of PET studies with normal subjects. J. Cognit. Neurosci. 9(1):1997;1-26.
16. Carter C.S., Mintun M., Nichols T., Cohen J.D. Anterior cingulate gyrus dysfunction and selective attention deficits in schizophrenia: [15O]H2O PET study during single-trial stroop task performance. Am. J. Psychiatry. 154:1997;1670-1675.
17. Csernansky J.G., Joshi S., Wang L., Haller J.W., Gado M., Miller J.P., Grenander U., Muller M.I. Hippocampal morphometry in schizophrenia by high dimensional brain mapping. Proc. Natl. Acad. Sci. USA. 95(19):1998;11406-11411.
18. Christison G.W., Casanova M., Weinberger D.R., Rawlings R., Kleinman J.E. A quantitative investigation of hippocampal pyramidal cell size, shape, and variability of orientation in schizophrenia. Arch. Gen. Psychiatry. 46:1989;1027-1032.
19. Deakin J.F.W., Slater P., Simpson M.D.C., Gilchrist A.C., Skan W.J., Royston M.C., Reynolds G.P., Cross A.J. Frontal cortical and left temporal glutamatergic dysfunction in schizophrenia. J. Neurochem. 52:1989;1781-1786.
20. Falkai P., Bogerts B., Rozumik M. Limbic pathology in schizophrenia: The entorhinal region - A morphometric study. Biol. Psychiatry. 24:1988;515-521.
21. Falkai P., Bogerts B. Cell loss in the hippocampus of schizophrenics. Euro. Arch. Psychiatr. Neurol. Sci. 236:1986;154-161.
22. Fredens K., Stengaard-Pederson K., Larsson L.-I. Localization of enkephalin and cholecystokinin immunoreactivities in the perforant path terminal fields of the rat hippocampal formation. Brain Res. 304:1984;255-263.
23. Gall C., Brecha N., Karten H.J., Chang K.J. Localization of enkephalin-like immunoreactivity to identified axonal and neuronal populations of the rat hippocampus. J. Comp. Neurol. 198:1981;335-350.
24. Gao X-M., Hashimoto T., Tamminga C.A. Phencyclidine (PCP) and dizocilpine (MK801) exert time-dependent effects on the expression of immediate early genes in rat brain. Synapse. 29:1998;14-28.
25. Gao X.-M., Shirakawa O., Du F., Tamminga C.A. Delayed regional metabolic actions of phencyclidine. Eur. J. Pharmacol. 241:1993;7-15.
26. 3H]-glutamate binding at hippocampal CA, NMDA receptors 24 hours after PCP. Neurosci. Lett. 174:1994;149-153.
27. Gao X.-M., Tamminga C.A. MK801 induces delayed regional increases in NMDA and kainate receptor binding in rat brain. J. Neural Transm. 101:1995;105-113.
28. Gao X.-M., Tamminga C.A. Phencyclidine produces changes in NMDA and kainate receptor binding in rat hippocampus over a 48 hour time course. Synapse. 23:1996;274-279.
29. Halgren E., Walter R.D., Cherlow D.G., Crandall P.H. Mental phenomena evoked by electrical stimulation of the human hippocampal formation and amygdala. Brain. 101:1978;83-117.
30. Harrison P., McLaughlin D., Kerwin R.W. Decreased hippocampal expression of a glutamate receptor gene in schizophrenia. Lancet. 337:1991;450-452.
31. Heckers S., Heinsen H., Heinsen Y.C., Beckmann H. Limbic structures and lateral ventricle in schizophrenia. A quantitative postmortem study. Arch. Gen. Psychiatry. 47:1990;1016-1022.
32. Heckers S., Heinsen H., Geiger B., Beckmann H. Hippocampal neuron number in schizophrenia. Arch. Gen. Psychiatry. 48:1991;1002-1008.
33. Heckers S., Rauch S.L., Goff D., Savage C.R., Schacter D.L.F.A.J., Alpert N.M. Impaired recruitment of the hippocampus during conscious recollection in schizophrenia. Nature. 1(4):1998;318-323.
34. Holcomb H.H., Caudill P.J., Medoff D.R., Zhao M., Lahti A.C., Ravert T., Dannals R.F., Tamminga C.A. Cerebral blood flow relationships associated with a difficult tone recognition task in trained normal volunteers. Cerebral Cortex. 8:1998;534-542.
35. Holcomb, H.H., Medoff, D.R., Lahti, A.C., Tamminga, C.A., Functional neuroimaging applied to the syndrome of schizophrenia: symptom, treatment and etiologic observations. APA Press, in Annual Review of Psychiatry, 1999, In Press.
36. Holcomb H.H., Tamminga C.A., Cascella N.G., Thaker G.K., Medoff D.R., Gastineau E.A., Loats E.A., Dannals R.F. Functional sites of neuroleptic drug action in human brain: PET/FDG studies with and without haloperidol. Am. J. Psychiatry. 153(1):1996;41-49.
37. Jakob H., Beckmann H. Prenatal developmental disturbances in the limbic allocortex in schizophrenics. J. Neural. Transm. 65:1986;303-326.
38. Jeste, D.V., Hippocampal pathology in neuropsychiatric illness. Paper presented at the 139th Annual Meeting of American Psychiatric Association, Washington, 1986.
39. Kerwin R.W., Patel S., Meldrum B.S. Autoradiographic localization of the glutamate receptor system in control and schizophrenic postmortem hippocampal formation. Neuroscience. 39:1990;25-32.
40. 1 region in postmortem brain determined by quantitative autoradiography. Neurosci. Lett. 118:1990;164-168.
41. Kerwin R.W., Patel S., Meldrum B.S., Czudek C., Reynolds G.P. Asymmetrical loss of glutamate receptor subtype in left hippocampus in schizophrenia. Lancet. XX:1988;583-584.
42. Kohler C., Chan-Palay V., Wu J.-Y. Septal neurons containing glutamic acid decarboxylase immunoreactivity project to the hippocampal region in the rat brain. Anat. Embryol. 169:1984;41-44.
43. Kovelman J.A., Scheibel A.B. A neurohistological correlate of schizophrenia. Biol. Psychiatry. 19:1984;1601-1621.
44. Lahti A.C., Holcomb H.H., Medoff D.R., Tamminga C.A. Ketamine activates psychosis in schizophrenia and alters blood flow in human limbic cortex. NeuroReport. 6:1995;869-872.
45. Lahti A.C., Holcomb H.H., Weiler M.A., Corey P.K., Zhao M., Medoff D., Tamminga C.A. Effects of ketamine on behavior and rCBF in schizophrenic and normal individuals. Biol. Psychiatry. 41:1997;165.
46. A.C. Lahti, H.H. Holcomb, M.A. Weiler, D.R. Medoff, T. Michaelidis, S. Fletcher, C.A. Tamminga, rCBR changes after acute antipsychotic medication in patients with schizophrenia. Society for Neuroscience, November 7-12, 1998, Los Angeles, CA.
47. A.C. Lahti, H.H. Holcomb, M.A. Weiler, D.R. Medoff, C.A. Tamminga, Comparison of rCBF changes after acute challenge with haloperidol and olanzapine in patients with schizophrenia, American College of Neuropsychopharmacology, December 14-18, 1998, San Juan, Puerto Rico.
48. LaPorte D.J., Hall C., Lahti A.C., Koffel B., Tamminga C.A. Absence of ketamine effects on memory and other cognitive functions in schizophrenic patients. J. Psychiatr. Res. 30:1996;321-330.
49. O.P. Ottersen, J. Storm-Mathisen, Excitatory and Inhibitory amino acids in the hippocampus, in: V. Chan-Palay, C. Kohler (Eds.), The Hippocampus-New Vistas, Alan R. Liss, 1989, pp. 97-117.
50. Reynolds G.P. Increased concentrations and lateral asymmetry of amygdala dopamine in schizophrenia. Nature. 305:1983;527-529.
51. Ribak C.E., Seress L. GABAergic cells in the dentate gyrus appear to be local circuit and projection neurons. Exp. Brain Res. 50:1983;173-182.
52. Scheibel A.B., Kovelman J.A. Disorientation of the hippocampal pyramidal cell and its processes in the schizophrenia patients. Biol. Psychiatry. 16:1981;101-102.
53. Schlander M., Thomalske G., Frotscher M. Fine structure of GABAergic neurons and synapses in the human dentate gyrus. Brain Res. 401:1987;185-189.
54. Shapiro R.M. Regional neuropathology in schizophrenia: where are we? Where are we going? Schizophr. Res. 10:1993;187-239.
55. Steinbush H.W.M. Distribution of serotonin-immunoreactivity in the central nervous system of the rat. Cell bodies and terminals. Neurosci. 6:1981;557-618.
56. Steward O., Scoville S.A. Cells of origin of entorhinal cortical afferents to the hippocampus and fascia dentata of the rat. J. Comp. Neurol. 169:1976;347-370.
57. Storm-Mathisen J. Glutamic acid and excitatory nerve endings: Reduction of glutamic acid uptake after axotomy. Brain Res. 120:1977;379-386.
58. L.W. Swanson, C. Kohler, A. Bjorklund, The limbic region. I:The septohippocampal system, in: A. Bjorklund, T. Hökfelt, and L.W. Swanson (Eds), Handbook of Chemical Neuroanatomy, Vol. 5: Integrated Systems of the CNS, part 1. Elsevier Science Publishers B.V., Amsterdam, 1987, pp. 125-277.
59. C.A. Tamminga, Neuropsychiatric aspects of schizophrenia, in: S.C. Yudofsky, R.E. Hales (Eds.), Neuropsychiatry, Third Edition, American Psychiatric Press, Washington, DC., 1997, pp. 855-882.
60. Tamminga C.A. Schizophrenia and glutamatergic transmission. Crit. Rev. Neurosci. 12:1998;21-36.
61. Tamminga C.A., Thaker G.K., Alphs L.D., Buchanan R.W., Kirkpatrick B., Carpenter W.T., Chase T.N. Limbic System Abnormalities in Schizophrenia; and, Neocortical Alterations with Deficit Syndrome. Arch. Gen. Psychiatry. 49:1992;522-530.
62. B.A., Vogt, L.J. Vogt, E.A. Nimchinsky, P.R. Hof, Primate cingulate cortex chemoarchitecture and its disruption in Alzheimer's disease, in: F.E. Bloom, A. Bjorklund, T. Hokfelt (Eds.), Handbook of Chemical Neuroanatomy, 13: The Primate Nervous System, Part 1, Elsevier, 1997, pp. 453-488.
63. B.A. Vogt, M. Gabriel (Eds.) Neurobiology of Cingulate Cortex and Limbic Thalamus, Boston: Birkh_user, 1993.
64. M.A. Weiler, A.C. Lahti, H.H. Holcomb, C.A. Tamminga, Blow flow effects of haloperidol and clozapine, Society for Neuroscience, November 7-12, 1998, Los Angeles, CA.
65. Weinberger D.R. On the plausibility of 'The Neurodevelopmental Hypothesis' of schizophrenia. Neuropsychoparm. 14:1996;1S-11S.
66. Weinberger D.R., Berman K.F., Suddath R., Torrey E.F. Evidence of dysfunction of prefrontal-limbic network in schizophrenia: a magnetic resonance imaging and regional cerebral blood flow study of discordant monozygotic twins. Am. J. Psychiatry. 149:1992;890-897.
67. Witter M.P., Groenewegen H.J., Lopes Da Silva F.H., Lohman A.H.M. Functional organization of the extrinsic and intrinsic circuitry of the parahippocampal region. Prog. Neurobiol. 33:1989;161-253.