Structural adaptation to selective pressure for altered ligand specificity in the Pseudomonas aeruginosa amide receptor, AmiC

Protein Engineering

Volumn 13, Issue 2, 2000, Pages 129-132

  O'Hara, Bernard P ^a,b   Wilson, Stuart A ^a,c   Lee, Alan W L ^a   Roe, S Mark ^a,d   Siligardi, Giuliano ^e   Drew, Robert E ^a   Pearl, Laurence H ^a,d  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF LONDON   (United Kingdom)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

^d INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^e KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Crystallography; Ligand specificity; Mutation; Protein evolution; Small molecule binding protein

Indexed keywords

ACETAMIDE; AMIDASE; AMIDE; ASPARAGINE; BUTYRIC ACID DERIVATIVE; LACTAM DERIVATIVE; LIGAND; MUTANT PROTEIN; RECEPTOR; REGULATOR PROTEIN; THREONINE;

ARTICLE; BINDING SITE; CRYSTAL STRUCTURE; ENZYME INDUCTION; GENE MUTATION; LIGAND BINDING; NONHUMAN; OPERON; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PSEUDOMONAS AERUGINOSA;

BACTERIA (MICROORGANISMS); NEGIBACTERIA; PSEUDOMONAS; PSEUDOMONAS AERUGINOSA;

EID: 0034061637     PISSN: 02692139     EISSN: None     Source Type: Journal    
DOI: 10.1093/protein/13.2.129     Document Type: Article

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