An alternate method for estimating the dose-response relationships of neuromuscular blocking drugs

Anesthesia and Analgesia

Volumn 90, Issue 5, 2000, Pages 1191-1197

  Kopman, Aaron F ^a,b   Klewicka, Monika M ^b   Neuman, George G ^a  

^a NEW YORK MEDICAL COLLEGE   (United States)

^b ST VINCENT S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NEUROMUSCULAR BLOCKING AGENT; NITROUS OXIDE; PROPOFOL; ROCURONIUM; SUXAMETHONIUM;

ANESTHESIA INDUCTION; ARTICLE; DOSE CALCULATION; DOSE RESPONSE; DRUG POTENCY; ELECTROMYOGRAPHY; HUMAN; MAJOR CLINICAL STUDY; NEUROMUSCULAR BLOCKING; PRIORITY JOURNAL; REGRESSION ANALYSIS;

EID: 0034060422     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000539-200005000-00036     Document Type: Article

References (22)

1. Viby-Mogensen J, Engbæk J, Eriksson LI, et al. Good clinical research practice (GCRP) in pharmacodynamic studies of neuromuscular blocking agents. Acta Anaesthiol Scand 1996;40: 59-74.
2. Belmont MR, Lien CA, Quessy S, et al. The clinical neuromuscular pharmacology of 51W89 in patients receiving nitrous oxide/opioid/barbiturate anesthesia. Anesthesiology 1995;82: 1139-45.
3. Koscielniak-Nielsen, ZJ, Law-Min JC, Donati F, et al. Dose-response relationships of doxacurium and its reversal with neostigmine in young adults and healthy elderly patients. Anesth Analg 1992;74:845-50.
4. Gibson FM, Mirakhur RK, Clarke RSJ, Lavery GG. Comparison of cumulative and single bolus dose technique for determining the potency of vecuronium. Br J Anaesth 1985;57:1060-2.
5. Meretoja OA, Wirtavuori K. Two-dose technique to create an individual dose-response curve for atracurium. Anesthesiology 1989;70:732-6.
6. Wright PMC, Hart P, Lau M, et al. Cumulative characteristics of atracurium and vecuronium: a simultaneous clinical and pharmacokinetic study. Anesthesiology 1994;81:59-68.
7. Donlon JV, Savarese JJ, Ali HH, Teplik RS. Human dose response curves for neuromuscular blocking drugs: a comparison of two methods of construction and analysis. Anesthesiology 1980;53:161-6.
8. Gibson FM, Mirakhur RK, Lavery GG, Clarke RSJ. Potency of atracurium: a comparison of single bolus and cumulative dose techniques. Anesthesiology 1985;62:657-9.
9. Gibson FM, Mirakhur RK, Clarke RSJ, Lavery GG. Comparison of cumulative and single bolus dose technique for determining the potency of vecuronium. Br J Anaesth 1985;57:1060-2.
10. Silverman DG, Brull SJ. Depth of block after divided doses of mivacurium spaced 60 seconds apart. Anesth Analg 1993;77: 164-7.
11. Maddineni VR, Mirakhur RK, Cooper R, McCoy E. Potency estimates of mivacurium: comparison of two different modes of nerve stimulation. Br J Anaesth 1993;70:694-5.
12. Wierda JMKH, Beaufort AM, Kleef UW, et al. Preliminary investigations of the clinical pharmacology of three short-acting agents, ORG 9453, ORG 9489, and ORG 9487. Can J Anaesth 1994;41:213-20.
13. Savarese JJ, Belmont MR, Lien CA, et al. Comparative neuromuscular blocking properties of GW 280430 and rocuronium in the thumb and larynx in human subjects [abstract]. Can J Anaesth 1999;46:A37.
14. Foldes F, Nagashima H, Nguyen HD, et al. The neuromuscular effects of ORG 9426 in patients receiving balanced anesthesia. Anesthesiology 1991;75:191-6.
15. Meistelman C, Plaud B, Donati F. Rocuronium (ORG 9426) neuromuscular blockade at the adductor muscles of the larynx and adductor pollicis in humans. Can J Anaesth 1992;39:665-9.
16. Bevan DR, Fiset P, Balendran P, et al. Pharmacodynamic behavior of rocuronium in the elderly. Can J Anaesth 1993;40:127-32.
17. Eisenkraft JB, Mingus ML, Herlich A, et al. A defasciculating dose of d-tubocurarine causes resistance to succinylcholine. Can J Anaesth 1990;37:538-42.
18. Szalados JE, Donati F, Bevan DR. Effect of d-tubocurarine pretreatment on succinylcholine twitch augmentation and neuromuscular blockade. Anesth Analg 1990;71:55-9.
19. Smith CE, Donati F, Bevan DR. Potency of succinylcholine at the diaphragm and at the adductor pollicis muscle. Anesth Analg 1988;67:625-30.
20. Smith CE, Donati F, Bevan DR. Dose-response curves for succinylcholine: single vs cumulative techniques. Anesthesiology 1988;69:338-42.
21. Chestnut RJ, Healy TEJ, Harper NJN, Faragher EB: Suxamethonium: the relation between dose and response. Anaesthesia 1989;44:14-8
22. Katz RL, Norman J, Seed RF, Conrad L. A comparison of the effects of succinylcholine and d-tubocurarine in patients in London and New York. Br J Anaesth 1969;41:1041-7.