Analysis of host response modifier ORFs of ectromelia virus, the causative agent of mousepox

Virus Research

Volumn 66, Issue 2, 2000, Pages 155-173

  Chen, Nanhai ^a   Buller, R Mark L ^a   Wall, Erika M ^b   Upton, Chris ^b  

^a S Louis Univ Hlth Sciences Center   (United States)

^b UNIVERSITY OF VICTORIA   (Canada)

Author keywords

Ectromelia virus; Immune modulator; Mousepox; Poxvirus; Virulence

Indexed keywords

BINDING PROTEIN; CHEMOKINE; TUMOR NECROSIS FACTOR; VIRUS DNA;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL LINE; CELL SECRETION; CELL STRAIN L 929; CONTROLLED STUDY; DNA SEQUENCE; ECTROMELIA VIRUS; EXPERIMENTAL INFECTION; FEMALE; GENETIC CODE; HISTOLOGY; IMMUNE RESPONSE; INFECTION; INFLAMMATION; KIDNEY CELL; MONKEY; MOUSE; NONHUMAN; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN SECRETION; VIRUS GENOME; VIRUS INFECTION; VIRUS PATHOGENESIS; VIRUS VIRULENCE;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, VIRAL; BIOLOGICAL RESPONSE MODIFIERS; CELL LINE; DNA TRANSPOSABLE ELEMENTS; ECTROMELIA VIRUS; ECTROMELIA, INFECTIOUS; FEMALE; GENOME, VIRAL; GLYCOPROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; MEMBRANE PROTEINS; MICE; MICE, INBRED A; MOLECULAR SEQUENCE DATA; OPEN READING FRAMES; RECEPTORS, CHEMOKINE; RECEPTORS, INTERFERON; RECEPTORS, INTERLEUKIN-1; RECEPTORS, TUMOR NECROSIS FACTOR; SEQUENCE ALIGNMENT; SEQUENCE DELETION; SERPINS; SKIN DISEASES, VIRAL; VIRAL PROTEINS; VIRULENCE;

ECTROMELIA VIRUS; ECTROMELIA VIRUS (STRAIN MOSCOW); POXVIRIDAE;

EID: 0034059870     PISSN: 01681702     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-1702(99)00135-5     Document Type: Article

References (78)

1. Alcami A., Smith G.L. A soluble receptor for interleukin-1β encoded by vaccinia virus: a novel mechanism of virus modulation of the host response to infection. Cell. 71:1992;153-167.
2. Alcami A., Smith G.L. Cytokine receptors encoded by poxviruses: a lesson in cytokine biology. Immunol. Today. 16:1995a;474-478.
3. Alcami A., Smith G.L. Vaccinia, cowpox and camelpox viruses encode soluble gamma interferon receptors with novel broad species specificity. J. Virol. 69:1995b;4633-4639.
4. Alcami A., Symons J.A., Collins P.D., Williams T.J., Smith G.L. Blockade of chemokine activity by soluble chemokine binding protein from vaccinia virus. J. Immunol. 160:1998;624-633.
5. Banham A.H., Leader D.P., Smith G.L. Phosphorylation of ribosomal proteins by the vaccinia virus B1R protein kinase. FEBS Lett. 321:1993a;27-31.
6. Banham A.H., Smith G.L. Characterization of vaccinia virus gene B12R. J. Gen. Virol. 74:1993b;2807-2812.
7. Beaud G. Vaccinia virus DNA replication: a short review. Biochimie. 77:1995a;774-779.
8. Beaud G., Beaud R., Leader D.P. Vaccinia virus gene H5R encodes a protein that is phosphorylated by the multisubstrate vaccinia virus B1R protein kinase. J. Virol. 69:1995b;1819-1826.
9. Bleasby A.J., Wootton J.C. Construction of validated, non-redundant composite protein sequence databases. Protein Eng. 3:1990;153-159.
10. Boursnell M.E., Foulds I.J., Campbell J.I., Binns M.M. Non-essential genes in the vaccinia virus HindIII K fragment: a gene related to serine protease inhibitors and a gene related to the 37K vaccinia virus major envelope antigen. J. Gen. Virol. 69:1988;2995-3003.
11. Brooks M.A., Ali A.N., Turner P.C., Moyer R.W. A rabbitpox virus serpin gene controls host range inhibiting apoptosis in restrictive cells. J. Virol. 69:1995;7688-7698.
12. Brownstein D.G., Bhatt P.N., Gras L., Budris T. Serial backcross analysis of genetic resistance to mousepox, using marker loci for Rmp-2 and Rmp-3. J. Virol. 66:1992;7073-7079.
13. Buller R.M.L., Palumbo G.K. Poxvirus pathogenesis. Microb. Rev. 55:1991;80-122.
14. Centers for Disease Control and Prevention, 1997. Human monkeypox-Kasai Oriental, Zaire, 1996-1997. Morb. Mortal. Wkly. Rep. 46, 304-307.
15. Chen W., Drillien R., Spehner D., Buller R.M.L. Restricted replication of ectromelia virus in cell culture correlates with mutations in virus-encoded host range gene. Virology. 187:1992;433-442.
16. Colamonici O.R., Domanski P., Sweitzer S.M., Lamer A., Buller R.M.L. Vaccinia virus B18R gene encodes a type I interferon-binding protein that blocks interferon a transmembrane signaling. J. Biol. Chem. 270:1995;15974-15978.
17. Dear S., Staden R. A sequence assembly and editing program for efficient management of large projects. Nucleic Acids Res. 19:1991;3907-3911.
18. Engelstad M., Howard S.T., Smith G.L. A constitutively expressed vaccinia gene encodes a 42-kDa glycoprotein related to complement control factors that forms part of the extracellular virus envelope. Virology. 188:1992;801-810.
19. Engelstad M., Smith G.L. The vaccinia virus 42-kDa envelope protein is required for the envelopment and egress of extracellular virus and for virus virulence. Virology. 194:1993;627-637.
20. Esposito J.J., Knight J.C. Orthopoxvirus DNA: a comparison of restriction profiles and maps. Virology. 143:1985;230-251.
21. Fenner F. The pathogenesis of the acute exanthems: an interpretation based on experimental investigation with mousepox (infectious ectromelia of mice). Lancet. 2:1948;915-930.
22. Fredrickson R.N., Sechler J.M.G., Palumbo G.J., Albert J., Khairallah L.H., Buller R.M.L. Acute inflammatory response to cowpox virus infection of the chorioallantoic membrane of the chick embryo. Virology. 187:1992;693-704.
23. Genetics Computer Group Program, 1994. Manual for the Wisconsin Package, Version 8.
24. Ghayur T., Banerjee S., Hugunin M., Butler D., Herzog L., Carter A., Quintal L., Sekut L., Talanian R., Paskine M., Wong W., Kamen R., Tracey D., Allen H. Caspase-1 processes IFNgamma inducing factor and regulates LPS induced IFNgamma induction. Nature. 386:1997;623.
25. Graham K.A., Lalani A.S., Macen J.L., Ness T.L., Barry M., Liu L.Y., Lucas A., Clark-Lewis I., Moyer R.W., McFadden G. The Tl/35kDa family of poxvirus-secreted proteins bind chemokines and modulate leukocyte influx into virus-infected tissues. Virology. 229:1997;12-24.
26. Gu Y., Kuida K., Tsutsui H., Ku G., Hsiao K., Fleming M.A., Hayashi N., Higashino K., Okamura H., Nakanishi K., Kurimoto M., Ranimoto T., Flavel R.A., Sato V., Harding M.W., Livingston D.J., Su M.S. Activation of IFNg inducing factor mediated by ICE. Science. 275:1997;206-209.
27. Hunter C.A., Timans J., Pisacane P., Menon S., Cai G., Walker W., Aste-Amegaza M., Chizzonite R., Bazan J.F., Kastelein R.A. Comparison of the effects of interleukin-1 alpha, interleukin-1 beta and interferon-gamma-inducing factor on the production of interferon-gamma by natural killer cells. Eur. J. Immunol. 27:1997;2787-2792.
28. Isaacs S.N., Wolffe E.J., Payne L.G., Moss B. Characterization of a vaccinia virus-encoded 42-kDa class I membrane glycoprotein component of the extracellular virus envelope. J. Virol. 66:1992;7217-7224.
29. Johnson G.P., Goebel S.J., Paoletti E. An update on the vaccinia virus genome. Virology. 196:1993;381401.
30. Karupiah G., Xie Q.-W., Buller R.M.L., Nathan C., Duarte C., MacMicking J. Inhibition of viral replication by interferon-γ-induced nitric oxide synthase. Science. 261:1993;1445-1448.
31. Kotwal G.J., Moss B. Vaccinia virus encodes two proteins that are structurally related to members of plasma serine protease inhibitor superfamily. J. Virol. 63:1989;600-606.
32. Loparev V.N., Parsons J.M., Knight J.C., Panus J.F., Ray C.A., Buller R.M., Pickup D.J., Esposito J.J. A distinctive tumor necrosis factor receptor isolog of ectromelia and cowpox viruses. Proc. Natl. Acad. Sci. USA. 95:1998;3786-3791.
33. Lux S.E., John K.M., Bennett V. Analysis of cDNA for human erythrocyte ankyrin indicates a repeated structure with homology to tissue-differentiation and cell-cycle control proteins. Nature. 344:1990;36-42.
34. Macen J.L., Garner R.S., Musy P.Y., Brooks M.A., Turner P.C., Moyer R.W., McFadden G., Bleackley R.C. Differential inhibition of the Fas- and granule-mediated cytolysis pathways by the orthopoxvirus cytokine response modifier A/SPI-2 and SPI-1 protein. Proc. Natl. Acad. Sci. USA. 93:1996;9108-9113.
35. Mackett M., Archard L.C. Conservation and variation in Orthopoxvirus genome structure. J. Gen. Virol. 45:1979;683-701.
36. Martinez-Pomares L., Stern R.J., Moyer R.W. The ps/hr gene (B5R open reading frame homolog) of rabbitpox virus controls pock color, is a component of extracellular enveloped virus, and is secreted into the medium. J. Virol. 67:1993;5450-5462.
37. Massung R.F., Esposito J.J., Liu L.I., Qi J., Utterback T.R., Knight J.C., Aubin L., Yuran T.E., Parsons J.M., Loparev V.N., Selivanov N.A., Cavallaro K.F., Kerlavage A.R., Mahy B.W., Venter J.C. Potential virulence determinants in terminal regions of variola smallpox virus genome. Nature. 366:1993;748-751.
38. Massung R.F., Liu L.I., Qi J., Knight J.C., Yuran T.E., Kerlavage A.R., Parsons J.M., Venter J.C., Esposito J.J. Analysis of the complete genome of smallpox variola major virus strain Bangladesh-1975. Virology. 201:1994;215-240.
39. Mossman K., Buller R.M.L., McFadden G. Species specificity of ectromelia virus and vaccinia virus interferon-gamma binding proteins. Virology. 208:1995a;762-769.
40. Mossman K., Upton C., McFadden G. The myxoma virus soluble interferon-γ receptor homolog, M-T7, inhibits interferon-gamma in a species specific manner. J. Biol. Chem. 270:1995b;3031-3038.
41. Nakai K., Kanehisa M. A knowledge base for predicting protein localization sites in eukaryotic cells. Genomics. 14:1992;897-911.
42. Nathan C. Nitric oxide as a secretory product of mammalian cells. FASEB. 6:1992;3051-3064.
43. Nielsen H., Engelbrecht J., Brunak S., von Heijne G. Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites. Protein Eng. 10:1997;1-6.
44. Okamura H., Tsutsui H.H., Komatsu T., Yutsudo M., Hakura A., Tanimoto T., Torigoe K., Okura T., Nukadc Y., Hattori K., Akita K., Namba F., Tanabe F., Konishi K., Fukuda S., Kurimoto M. Cloning of a new cytokine that induces interferon γ production by T-cells. Nature. 378:1995;88-91.
45. Palumbo G.J., Buller R.M., Glasgow W.C. Multigenic evasion of inflammation by poxviruses. J. Virol. 68:1994;1737-1749.
46. Palumbo G.J., Glasgow W.C., Buller R.M.L. Poxvirus-induced alteration of arachidonate metabolism. Proc. Natl. Acad. Sci. USA. 90:1993;2020-2024.
47. Pearson W.R., Lipman D.J. Improved tools for biological sequence comparison. Proc. Natl. Acad. Sci. USA. 85:1988;2444-2448.
48. Perkus M.E., Goebel S.J., Davis S.W., Johnson G.P., Norton E.K., Paoletti E. Deletion of 55 open reading frames from the termini of vaccinia virus. Virology. 180:1991;406-410.
49. Pickup D.J. Poxviral modifiers of cytokine responses to infection. Infect. Agents Dis. 3:1994;116-127.
50. Pickup D.J., Ink B.S., Hu W., Ray C.A., Joklik W.K. Hemorrhage in lesions caused by cowpox virus is induced by a viral protein that is related to plasma protein inhibitors of serine proteases. Proc. Natl. Acad. Sci. USA. 83:1986;7698-7702.
51. Quan L.T., Caputo A., Bleackley R.C., Pickup D.J., Salvesen G.S. Granzyme B is inhibited by the cowpox virus serpin cytokine response modifier A. J. Biol. Chem. 270:1995;10377-10379.
52. Ray C.A., Black R.A., Koronheim S.R., Greenstreet T.A., Sleath P.R., Salvesen G.S., Pickup D.J. Viral inhibition of inflammation; cowpox virus encodes an inhibitor of the interleukin-1b converting enzyme. Cell. 69:1992;597-604.
53. Schreiber M., McFadden G. Mutational analysis of the ligand-binding domain of M-T2 protein, the tumor necrosis factor receptor homologue of myxoma virus. J. Immunol. 157:1996;4486-4495.
54. Schreiber M., Sedger L., McFadden G. Distinct domains of M-T2, the myxoma virus tumor necrosis factor (TNF) receptor homolog, mediate extracellular TNF binding and intracellular apoptosis inhibition. J. Virol. 71:1997;2171-2181.
55. Senkevich T.G., Bugert J., Sisler J.R., Koonin E.V., Darai G., Moss B. Genome sequence of a human tumorigenic poxvirus: prediction of specific host response-evasion genes. Science. 273:1996;813-816.
56. Senkevich T.G., Koonin E.V., Bugert J., Darai G., Moss B. The genome of molluscum contagiosum virus: analysis and comparison with other poxviruses. Virology. 233:1997;19-42.
57. Senkevich T.G., Muravnik G.L., Pozdnyakov S.G., Chizhikov V.E., Ryazankina O.I., Shchelkunov S.N., Koonin E.V., Chernos V.I. Nucleotide sequence of XhoI O fragment of ectromelia virus DNA reveals significant differences from vaccinia virus. Virus Res. 30:1993;73-88.
58. Shchelkunov S.N., Blinov V.M., Resenchuk S.M., Totmenin A.V., Olenina L.V., Chirikova G.B., Sandakhchiev L.S. Analysis of the nucleotide sequence of 53 kbp from the right terminus of the genome of variola major virus strain India-1967. Virus Res. 34:1994a;207-236.
59. Shchelkunov S.N., Resenchuk S.M., Totmenin A.V., Blinov V.M., Sandakhchiev L.S. Analysis of the nucleotide sequence of 48 kbp of the variola major virus strain India-1967 located on the right terminus of the conservative genome region. Virus Res. 32:1994b;37-55.
60. Shchelkunov S.N., Safronov P.F., Totmenin A.V., Petrov N.A., Ryazankina O.I., Gutorov V.V., Kotwal G.J. The genomic sequence analysis of the left and right species-specific terminal region of a cowpox virus strain reveals unique sequences and a cluster of intact ORFs for immunomodulatory and host range proteins. Virology. 243:1998;432-460.
61. Shchelkunov S.N., Totmenin A.V. Two types of deletions in orthopoxvirus genomes. Virus Genes. 9:1995;231-245.
62. Smith C.A., Smith T.D., Smolak P.J., Friend D., Hagen H.G.M., Park L., Pickup D.J., Torrance D., Mohler K., Schooley K., Goodwin R.G. Poxvirus genomes encode a secreted, soluble protein that preferentially inhibits b chemokine activity yet lacks sequence homology to known chemokine receptors. Virology. 236:1997;316-327.
63. Smith G.L., Chan Y.S. Two vaccinia virus proteins structurally related to the interleukin-1 receptor an the immunoglobulin superfamily. J. Gen. Virol. 72:1991;511-518.
64. Smith G.L., Howard S.T., Chan Y.S. Vaccinia virus encodes a family of genes with homology to serine proteinase inhibitors. J. Gen. Virol. 70:1989;2333-2343.
65. Spriggs M.K., Hruby D.E., Maliszewksi C.R., Pickup D.J., Sims J.E., Buller R.M.L., VanSlyke J. Vaccinia and cowpox viruses encode a novel secreted interleukin-1-binding protein. Cell. 71:1992;145-152.
66. Springer T.A. Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell. 76:1994;301-314.
67. Symons J.A., Alcami A., Smith G.L. Vaccinia virus encodes a soluble type I interferon receptor of novel structure and broad species specificity. Cell. 81:1995;551-560.
68. Tewari M., Dixit V.M. Fas- and tumor necrosis factor-induced apoptosis is inhibited by the poxvirus crmA gene product. J. Biol. Chem. 270:1995;3255-3260.
69. Traktman P., Anderson M.K., Rempel R.E. Vaccinia virus encodes an essential gene with strong homology to protein kineses. J. Biol. Chem. 264:1989;21458-21461.
70. Traktman P., Caligiuri A., Jesty S.A., Liu K., Sankar U. Temperature-sensitive mutants with lesions the vaccinia virus F10 kinase undergo arrest at the earliest stage of virion morphogenesis. J. Virol. 69:1995;6581-6587.
71. Tsutsui H., Matsui K., Kawada N., Hyodo Y., Hayashi N., Okamura H., Higashimo K., Nakanishi K. IL-18 accounts for both TNF-alpha- and Fas-ligand-mediated hepatotoxic pathways in endotoxininduced liver injury in mice. J. Immunol. 159:1997;3961-3967.
72. Upton C., McFadden G. Tumorigenic poxviruses: analysis of viral DNA sequences implicated in the tumorigenicity of Shope fibroma virus and malignant rabbit virus. Virology. 152:1986;308-321.
73. Upton C., Mossman K., McFadden G. Encoding of a homolog of the IFN-gamma receptor by myxom virus. Science. 258:1992;1369-1372.
74. Wallace G.D., Buller R.M.L. Kinetics of ectromelia virus (mousepox) transmission and clinical response in C57BL/6J, BALBcByJ and AKR/J inbred mice. Lab. Anim. Sci. 35:1985;41-46.
75. Walter M.R., Windsor W.T., Nagabhushan T.L., Lundell D.J., Lunn C.A., Zauodny P.J., Narula S.K. Crystal structure of a complex between interferon-γ and its soluble high-affinity receptor. Nature. 376:1995;230-235.
76. Wang S., Shuman S. Vaccinia virus morphogenesis is blocked by temperature-sensitive mutations in the F10 gene, which encodes protein kinase 2. J. Virol. 69:1995;6376-6388.
77. Weber C., Alon R., Moser B., Springer T.A. Sequential regulation of alpha 4 beta 1 and alpha 5 beta 1 integrin avidity by CC chemokines in monocytes: implications for transendothelial chemotaxis. J. Cell Biol. 134:1996;1063-1073.
78. Wolffe E.J., Isaacs S.N., Moss B. Deletion of the vaccinia virus B5R gene encoding a 42-kDa membrane glycoprotein inhibits extracellular virus envelope formation and dissemination. J. Virol. 67:1993;4732-4741.