Bcl-2, bcl-x, and bax expression in dysembryoplastic neuroepithelial tumors

Clinical Neuropathology

Volumn 19, Issue 2, 2000, Pages 57-62

  Prayson, R A ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Apoptosis; bax; Bcl 2; bcl x; Dysembryoplastic neuroepithelial tumor; MIB 1

Indexed keywords

PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL X; REGULATOR PROTEIN;

ADOLESCENT; ADULT; APOPTOSIS; ARTICLE; ASTROCYTE; CELL SURVIVAL; CHILD; CLINICAL ARTICLE; DYSPLASIA; FEMALE; HUMAN; HUMAN TISSUE; MALE; NERVE CELL; NEUROEPITHELIOMA; OLIGODENDROGLIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEIZURE; TERATOMA;

ADOLESCENT; ADULT; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; BRAIN; BRAIN NEOPLASMS; CHILD; CHILD, PRESCHOOL; EPILEPSY; FEMALE; FOLLOW-UP STUDIES; HUMANS; IMMUNOENZYME TECHNIQUES; MALE; MIDDLE AGED; NEUROECTODERMAL TUMORS, PRIMITIVE; NEUROGLIA; NEURONS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 0034058394     PISSN: 07225091     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Chao DT, Korsmeyer SJ 1998 Bcl-2 family: Regulators of cell death. Annu Rev Immunol 16: 395-419
2. Daumas Duport C, Scheithauer BW, Chodkiewicz JP, Laws Jr ER, Vedrenne C 1988 Dysembryoplastic neuroepithelial tumor A surgically curable tumor of young patients with intractable partial seizures. Neurosurgery 23: 545-556
3. Daumas-Duport C 1993 Dyserabryoplastic neuroepithelial tumours. Brain Pathol 3, 283-295
4. Farlie PG, Dringen R, Rees SM, Kannourakis G, Bernard O 1995 Bcl-2 transgene expression can protect neurons against developmental and induced cell death. Proc Natl Acad Sci USA 92: 4397-4401
5. Ferrer I, Tortosa A, Condom E, Blanco R, Macaya A, Planas A 1994 Increased expression of bcl-2 immunoreactivity in the developing cerebral cortex of the rat. Neurosci Lett 179. 13-16
6. Goldblum JR, Shannon R, Kaljiam EP, Thiny M, Davenport R, Thompson N, Lloyd RV 1993 Immunohistochemical assessment of proliferative activity in adrenocortical neoplasms. Mod Pathol 6: 663-668
7. González-García M, García I, Ding L, O'Shea S, Boise LH, Thompson CB, Núñz G 1995 Bcl-x is expressed in embryonic and postnatal neural tissues and functions to prevent neuronal death. Proc Natl Acad Sci USA 92 4304-4308
8. Granville DJ, Carthy CM, Hunt DWC, McManus BM 1998 Apoptosis: Molecular aspects of cell death and disease Lab Invest 78: 893-913
9. Hara A, Hirose Y, Wang A, Yoshimi N, Tamaka T, Mori, H 1996 Localization of bax and bcl-2 proteins, regulators of programmed cell death, in the human central nervous system. Virchows Arch 429 249-253
10. Hara A, Hirose Y, Yoshimi N, Tanaka T, Mori H 1997 Expression of bax and bcl-2 proteins, regulators of programmed cell death, in human brain tumors Neurol Res 19: 623-628
11. Hirose T, Scheithauer BW, Lopes MBS, VandenBerg SR 1994 Dysembryoplastic neuroepithelial tumor (DNT): An immunohistochemical and ultrastructural study. J Neuropathol Exp Neurol 53: 184-195
12. Hirose T, Scheithauer BW 1998 Mixed dysembryoplastic neuroepithelial tumor and ganglioglioma. Acta Neuropathol 95. 649-654
13. Honavar M, Janota I, Polkey CE 1999 Histological heterogeneity of dysembryoplastic neuroepithelial tumour: identification and differential diagnosis in a series of 74 cases. Histopathology 34: 342-356
14. Kleihues P, Burger PC, Scheithauer BW 1993 Histological Typing of Tumors of the Central Nervous System (2nd ed). World Health Organization, Geneva
15. Krajewski S, Krajewska M, Shabaik A, Miyashita T. Wang HG, Reed JC 1994 Immunohistochemical determination of in vivo distribution of bax, a dominant inhibitor of bcl-2. Am J Pathol 145: 1323-1336
16. Krajewski S, Krajewska AM, Ehrmann J, Sikorska M, Lach B, Chatten J, Reed JC 1997 Immunohistochemical analysis of bcl-2, bcl-x, mcl-1, and bax in tumors of central and peripheral nervous system origin. Am J Pathol 150: 805-814
17. Motoyama N, Wang F, Roth KA, Sawa H, Nakayama K, Negishi I, Senju S, Zhang Q, Fujii S, Loh DY 1995 Massive cell death of immature hematopoetic cells and neurons in bcl-x-deficient mice. Science 267; 1506-1510
18. Newcomb EW, Bhalla SK, Parrish CL, Hayes RL, Cohen H, Miller DC 1997 Bcl-2 protein expression in astrocytomas in relation to patient survival and p53 gene status. Acta Neuropathol 94: 369-375
19. L is an antiapoptotic regulator for postnatal CNS neurons. J Neurosci 18 1009-1019
20. Prayson RA, Khajavi K, Comair YG 1995 Cortical architectural abnormalities and MIB1 immunoreactivity in gangliogliomas: A study of 60 patients with intracranial tumors. J Neuropathol Exp Neurol 54: 513-520
21. Prayson RA 1999 Bcl-2 and bcl-x expression in gangliogliomas. Hum Pathol 30: 701-705
22. Prayson RA 1999 Composite ganglioglioma and dysembryoplastic neuroepithelial tumor. Arch Pathol Lab Med 123: 247-250
23. Prayson RA, Morris HH, Estes ML, Comair YG 1996 Dysembryoplastic neuroepithelial tumor: a clinicopathologic and immunohistochemical study of 11 tumors including MIB1 immunoreactivity. Clin Neuropathol 15: 47-53
24. Raymond AA, Halpin FS, Alsanjari N, Cook MJ, Kitchen ND, Fish DR, Stevens JM, Harding BN, Scaravilli F, Kendall B, Shorvon SD, Neville BGR 1994 Dysembryoplastic neuroepithelial tumour. Features in 16 patients. Brain 117: 461-475
25. Taratuto AL, Pomato H, Sevlever G, Gallo G, Monges J 1995 Dysembryoplastic neuroepithelial tumor. Morphological, immunocytochemical, and deoxyribonucleic acid analyses in a pediatric series. Neurosurgery 36: 474-481
26. Tubbs RR, Sheibani K 1984 Immunohistology of lymphoproliferative disorders. Semin Diagn Pathol 1: 272-284
27. Vekrellis K, McCarthy MJ, Watson A, Whifield J, Rubin LL, Ham J 1997 Bax promotes neuronal cell death and is downregulated during the development of the nervous system. Development 124. 1239-1249
28. Volk EE, Prayson RA 1997 Hamartomas in the setting of chronic epilepsy: A clinicopathologic study of 13 cases. Hum Pathol 28: 227-232
29. Wolf HK, Wellmer J, Mütter MB, Wieatler OD, Hufnagel A, Pietsch T 1995 Ghoneuronal malformative lesions and dysembryoplastic neuroepithelial tumor in patients with chronic pharmacoresistant epilepsies. J Neuropathol Exp Neurol 54: 245-254
30. Wolf HK, Müller MB, Spänle M, Zentner J, Schramm J, Wiestler OD 1994 Ganglioglioma: a detailed histopathological and immunohistochemical analysis of 61 cases. Acta Neuropathol 88: 166-173
31. Yachnis AT, Powell SZ, Olmstead JJ, Eskin TA 1997 Distinct neurodevelopmental patterns of bcl-2 and bcl-x expression are altered in glioneuronal hamartias of the human temporal lobe. J Neuropathol Exp Neurol 56: 186-198