Bypass flow, mean arterial pressure, and cerebral perfusion during cardiopulmonary bypass in dogs

Journal of Cardiothoracic and Vascular Anesthesia

Volumn 14, Issue 1, 2000, Pages 25-28

  Sungurtekin, Hulya ^a,b   Boston, Umar S ^a   Cook, David J ^a,c  

^a MAYO CLINIC   (United States)

^b SCIENTIFIC AND TECHNOLOGICAL RESEARCH COUNCIL OF TURKEY   (Turkey)

^c NONE   (United States)

Author keywords

Brain; Cardiopulmonary bypass; Cerebral blood flow; Mean arterial pressure; Pump flow

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN PERFUSION; CARBON DIOXIDE TENSION; CARDIOPULMONARY BYPASS; CARDIOPULMONARY HEMODYNAMICS; DOG; HEMATOCRIT; MEAN ARTERIAL PRESSURE; NONHUMAN; OXYGEN TENSION; PRIORITY JOURNAL;

EID: 0034058322     PISSN: 10530770     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1053-0770(00)90051-X     Document Type: Article

References (23)

1. Fox LS, Blackstone EH, Kirklin JW, et al: Relationship of whole body oxygen consumption to perfusion flow rate during hypothermic cardiopulmonary bypass. J Thorac Cardiovasc Surg 83:239-248, 1982
2. Hickey RF, Hoar PF: Whole-body oxygen consumption during low-flow hypothermic cardiopulmonary bypass. J Thorac Cardiovasc Surg 86:903-906, 1983
3. Tominaga R, Kurisu K, Fukumura F, et al: Effects of pump flow rate on oxygen use during moderate hypothermic cardiopulmonary bypass. ASAIO J 39:126-131, 1993
4. Sadahiro M, Haneda K, Mohri H: Experimental study of cerebral autoregulation during cardiopulmonary bypass with or without pulsatile perfusion. J Thorac Cardiovasc Surg 108:446-454, 1994
5. Cook DJ, Proper JA, Orszulak TA, et al: Effect of pump flow rate on cerebral blood flow during hypothermic cardiopulmonary bypass in adults. J Cardiothorac Vasc Anesth 11:415-419, 1997
6. Rogers AT, Prough DS, Roy RC, et al: Cerebrovascular and cerebral metabolic effects of alterations in perfusion flow rate during hypothermic cardiopulmonary bypass in man. J Thorac Cardiovasc Surg 103:363-368, 1992
7. Cook DJ, Orszulak TA, Daly RC: The effects of pulsatile cardiopulmonary bypass on cerebral and renal blood flow in dogs. J Cardiovasc Vasc Anesth 11:420-427, 1997
8. O'Dwyer C, Woodson LC, Conroy BP, et al: Regional perfusion abnormalities with phenylephrine during normothermic bypass. Ann Thorac Surg 63:728-735, 1997
9. Schwartz AE, Sandhu AA, Kaplon RJ, et al: Cerebral blood flow is determined by arterial pressure and not cardiopulmonary bypass flow rate. Ann Thorac Surg 60:165-169, 1995
10. Michenfelder JD, Milde JH: The relationship among canine brain temperature, metabolism, and function during hypothermia. Anesthesiology 75:130-136, 1991
11. Read RC, Kuida H, Johnson JA: Effect of alterations in vasomotor tone on pressure-flow relationships in the totally perfused dog. Circ Res 5:676-682, 1957
12. Swain JA, McDonald TJ Jr, Griffith PK, et al: Low-flow hypothermic cardiopulmonary bypass protects the brain. J Thorac Cardiovasc Surg 102:76-84, 1991
13. Rebeyka IM, Coles JG, Wilson GJ, et al: The effect of low-flow cardiopulmonary bypass on cerebral function: An experimental and clinical study. Ann Thorac Surg 43:391-396, 1987
14. Kern FH, Ungerleider RM, Reves JG, et al: Effect of altering pump flow rate on cerebral blood flow and metabolism in infants and children. Ann Thorac Surg 56:1366-1372, 1993
15. Swain JA, Anderson RV, Siegman MG: Low-flow cardiopulmonary bypass and cerebral protection: A summary of investigations. Ann Thorac Surg 56:1490-1492, 1993
16. Hindman BJ, Funatsu N, Harrington J, et al: Differences in cerebral blood flow between alpha-stat and pH-stat management are eliminated during periods of decreased systemic flow and pressure: A study during cardiopulmonary bypass in rabbits. Anesthesiology 74: 1096-1102, 1991
17. Fox LS, Blackstone EH, Kirklin JW, et al: Relationship of brain blood flow and oxygen consumption to perfusion flow rate during profoundly hypothermic cardiopulmonary bypass: An experimental study. J Thorac Cardiovasc Surg 87:658-664, 1984
18. Mutch WAC, Sutton IR, Teskey JM, et al: Cerebral pressure-flow relationship during cardiopulmonary bypass in the dog at normothermia and moderate hypothermia. J Cereb Blood Flow Metab 14:510-518, 1994
19. Newman MF, Croughwell ND, White WD, et al: Effect of perfusion pressure on cerebral blood flow during normothermic cardiopulmonary bypass. Circulation 94:II-353-II-357, 1996
20. Alston RP, Murray L, McLaren AD: Changes in hemodynamic variables during hypothermic cardiopulmonary bypass: Effects of flow rate, flow character, and arterial pH. J Thorac Cardiovasc Surg 100:134-144, 1990
21. Newman MF, Croughwell ND, Blumenthal JA, et al: Effect of aging on cerebral autoregulation during cardiopulmonary bypass: Association with postoperative cognitive dysfunction. Circulation 90:11-243-II-249, 1994
22. Plochl W, Cook DJ, Orszulak TA, et al: Critical cerebral perfusion pressure during tepid heart surgery in dogs. Ann Thorac Surg 66:118-124, 1998
23. Schwartz AE, Kaplon RJ, Young WL, et al: Cerebral blood flow during low-flow hypothermic cardiopulmonary bypass in baboons. Anesthesiology 81:959-964, 1994