메뉴 건너뛰기




Volumn 13, Issue 2, 2000, Pages 89-95

Mechanisms of protein degradation: What do the rat studies tell us

Author keywords

Branched chain amino acids; Glucocorticoids; Insulin; Metabolic acidosis; Ubiquitin

Indexed keywords

2 OXOISOVALERATE DEHYDROGENASE (LIPOAMIDE); BICARBONATE; BRANCHED CHAIN AMINO ACID; GLUCOCORTICOID; INSULIN; PROTEASOME; PROTEIN; UBIQUITIN; UREA;

EID: 0034057796     PISSN: 11218428     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (10)

References (34)
  • 2
    • 0008842115 scopus 로고
    • The alkaline treatment of chronic nephritis
    • Lyon DM, Dunlop DM, Stewart CP. The alkaline treatment of chronic nephritis. Lancet 1931; 2: 1009-113.
    • (1931) Lancet , vol.2 , pp. 1009-1113
    • Lyon, D.M.1    Dunlop, D.M.2    Stewart, C.P.3
  • 3
    • 0014899406 scopus 로고
    • Urea metabolism in patients with chronic renal failure: Influence of sodium bicarbonate or sodium chloride administration
    • Blom van Assendelf PM, Dorhout Mees EJ. Urea metabolism in patients with chronic renal failure: Influence of sodium bicarbonate or sodium chloride administration. Metabolism 1970; 19: 1053-63.
    • (1970) Metabolism , vol.19 , pp. 1053-1063
    • Blom Van Assendelf, P.M.1    Dorhout Mees, E.J.2
  • 4
    • 0021232948 scopus 로고
    • The effect of the correction of metabolic acidosis on nitrogen and potassium balance of patients with chronic renal failure
    • Papadoyannakis NJ, Stefanidis CJ, McGeown M. The effect of the correction of metabolic acidosis on nitrogen and potassium balance of patients with chronic renal failure. Am J Clin Nutr 1984; 40: 623-7.
    • (1984) Am J Clin Nutr , vol.40 , pp. 623-627
    • Papadoyannakis, N.J.1    Stefanidis, C.J.2    McGeown, M.3
  • 5
    • 0023502657 scopus 로고
    • McCollum award lecture. Kinetics of human amino acid metabolism: Nutritional implications and some lessons
    • Young VR. McCollum award lecture. Kinetics of human amino acid metabolism: Nutritional implications and some lessons. Am J Clin Nutr 1987; 46: 709-25.
    • (1987) Am J Clin Nutr , vol.46 , pp. 709-725
    • Young, V.R.1
  • 6
    • 0029063190 scopus 로고
    • Why are dialysis patients malnourished?
    • Bergstrom J. Why are dialysis patients malnourished? Am J Kidney Dis 1995; 26: 229-41.
    • (1995) Am J Kidney Dis , vol.26 , pp. 229-241
    • Bergstrom, J.1
  • 7
    • 0024230519 scopus 로고
    • Determination of activity and activity state of branched-chain α-ketoacid dehydrogenase complex and of activator protein in mitochondria, cells and tissues
    • Goodwin GW, Zhang B, Paxton R, Harris RA. Determination of activity and activity state of branched-chain α-ketoacid dehydrogenase complex and of activator protein in mitochondria, cells and tissues. Meth Enzymol 1988; 166: 175-88.
    • (1988) Meth Enzymol , vol.166 , pp. 175-188
    • Goodwin, G.W.1    Zhang, B.2    Paxton, R.3    Harris, R.A.4
  • 8
    • 0023201780 scopus 로고
    • Branched-chain amino acid metabolism in rat muscle: Abnormal regulation in acidosis
    • May RC, Hara Y, Kelly RA, Mitch WE. Branched-chain amino acid metabolism in rat muscle: Abnormal regulation in acidosis. Am J Physiol 1987; 252: E712-18.
    • (1987) Am J Physiol , vol.252
    • May, R.C.1    Hara, Y.2    Kelly, R.A.3    Mitch, W.E.4
  • 9
    • 0026099550 scopus 로고
    • Extracellular acidification changes protein synthesis and degradation in BC3H-1 myocytes
    • England BK, Chastain J, Mitch WE. Extracellular acidification changes protein synthesis and degradation in BC3H-1 myocytes. Am J Physiol 1991; 260: C277-82.
    • (1991) Am J Physiol , vol.260
    • England, B.K.1    Chastain, J.2    Mitch, W.E.3
  • 10
    • 0026695911 scopus 로고
    • Chronic metabolic acidosis accelerates whole body proteolysis and leucine oxidation in awake rats
    • May RC, Masud T, Logue B, Bailey J, England B. Chronic metabolic acidosis accelerates whole body proteolysis and leucine oxidation in awake rats. Kidney Int 1992; 41: 1535-42.
    • (1992) Kidney Int , vol.41 , pp. 1535-1542
    • May, R.C.1    Masud, T.2    Logue, B.3    Bailey, J.4    England, B.5
  • 11
    • 0023544639 scopus 로고
    • Acidosis, not azotemia, stimulates branched-chain amino acid catabolism in uremic rats
    • Hara Y, May RC, Kelly RA, et al. Acidosis, not azotemia, stimulates branched-chain amino acid catabolism in uremic rats. Kidney Int 1987; 32: 808-14.
    • (1987) Kidney Int , vol.32 , pp. 808-814
    • Hara, Y.1    May, R.C.2    Kelly, R.A.3
  • 12
    • 0028873202 scopus 로고
    • Rat muscle branched-chain ketoacid dehydrogenase activity and niRNAs increase with extracellular acidemia
    • England BK, Greiber S, Mitch WE, et al. Rat muscle branched-chain ketoacid dehydrogenase activity and niRNAs increase with extracellular acidemia. Am J Physiol 1995; 268: C1395-400.
    • (1995) Am J Physiol , vol.268
    • England, B.K.1    Greiber, S.2    Mitch, W.E.3
  • 13
    • 0029945963 scopus 로고    scopus 로고
    • Glucocorticoids and acidosis stimulate protein and amino acid catabolism in vivo
    • May RC, Bailey JL, Mitch WE, Masud T, England BK. Glucocorticoids and acidosis stimulate protein and amino acid catabolism in vivo. Kidney Int 1996; 49: 679-83.
    • (1996) Kidney Int , vol.49 , pp. 679-683
    • May, R.C.1    Bailey, J.L.2    Mitch, W.E.3    Masud, T.4    England, B.K.5
  • 14
    • 0031716769 scopus 로고    scopus 로고
    • Tissue-specific responses of branched-chain α-ketoacid dehydrogenase activity in metabolic acidosis
    • Price SR, Wang X, Bailey JL. Tissue-specific responses of branched-chain α-ketoacid dehydrogenase activity in metabolic acidosis. J Am Soc Nephrol 1998; 9: 1892-8.
    • (1998) J Am Soc Nephrol , vol.9 , pp. 1892-1898
    • Price, S.R.1    Wang, X.2    Bailey, J.L.3
  • 15
    • 0023160486 scopus 로고
    • Mechanisms for defects in muscle protein metabolism in rats with chronic uremia: The influence of metabolic acidosis
    • May RC, Kelly RA, Mitch WE. Mechanisms for defects in muscle protein metabolism in rats with chronic uremia: The influence of metabolic acidosis.J Clin Invest 1987; 79: 1099-103.
    • (1987) J Clin Invest , vol.79 , pp. 1099-1103
    • May, R.C.1    Kelly, R.A.2    Mitch, W.E.3
  • 16
    • 0029163339 scopus 로고
    • Experimental acidemia and muscle cell pH in chronic acidosis and renal failure
    • Bailey JL, England BK, Long RC, et al. Experimental acidemia and muscle cell pH in chronic acidosis and renal failure. Am J Physiol 1995; 269: C706-12.
    • (1995) Am J Physiol , vol.269
    • Bailey, J.L.1    England, B.K.2    Long, R.C.3
  • 17
    • 0022551936 scopus 로고
    • Metabolic acidosis stimulates protein degradation in rat muscle by a glucocorticoid-dependent mechanism
    • May RC, Kelly RA, Mitch WE. Metabolic acidosis stimulates protein degradation in rat muscle by a glucocorticoid-dependent mechanism. J Clin Invest 1986; 77: 614-21.
    • (1986) J Clin Invest , vol.77 , pp. 614-621
    • May, R.C.1    Kelly, R.A.2    Mitch, W.E.3
  • 18
    • 0029983847 scopus 로고    scopus 로고
    • Protein degradation and increased mRNAs encoding proteins of the ubiquitin-proteasome pathway in BC3H-1 myocytes requires an interaction between glucocorticoids and acidification
    • Isozaki Y, Mitch WE, England BK, Price SR. Protein degradation and increased mRNAs encoding proteins of the ubiquitin-proteasome pathway in BC3H-1 myocytes requires an interaction between glucocorticoids and acidification. Proc Natl Acad Sci USA 1996; 93: 1967-71.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 1967-1971
    • Isozaki, Y.1    Mitch, W.E.2    England, B.K.3    Price, S.R.4
  • 19
    • 0033060435 scopus 로고    scopus 로고
    • Evaluation of signals activating ubiquitin-proteasome proteolysis in a model of muscle wasting
    • Mitch WE, Bailey JL, Wang X, Jurkovitz C, Newby D, Price SR. Evaluation of signals activating ubiquitin-proteasome proteolysis in a model of muscle wasting. Am J Physiol 1999; 276: C1132-8.
    • (1999) Am J Physiol , vol.276
    • Mitch, W.E.1    Bailey, J.L.2    Wang, X.3    Jurkovitz, C.4    Newby, D.5    Price, S.R.6
  • 20
    • 0029861468 scopus 로고    scopus 로고
    • Muscle wasting in insulinopenic rats results from activation of the ATP-dependent, ubiquitin-proteasome pathway by mechanism including gene transcription
    • Price SR, Bailey JL, Wang X, Jurkovitz C, England BK, Ding X, Phillips LS, Mitch WE. Muscle wasting in insulinopenic rats results from activation of the ATP-dependent, ubiquitin-proteasome pathway by mechanism including gene transcription. J Clin Invest 1996; 98: 1703-8.
    • (1996) J Clin Invest , vol.98 , pp. 1703-1708
    • Price, S.R.1    Bailey, J.L.2    Wang, X.3    Jurkovitz, C.4    England, B.K.5    Ding, X.6    Phillips, L.S.7    Mitch, W.E.8
  • 21
    • 0029978889 scopus 로고    scopus 로고
    • Impaired actions of insulin-like growth factor-1 on protein synthesis and degradation in skeletal muscle of rats with chronic renal failure: Evidence for a postreceptor defect
    • Ding H, Gao X-L, Hirschberg R, Vadgama JV, Kopple JD. Impaired actions of insulin-like growth factor-1 on protein synthesis and degradation in skeletal muscle of rats with chronic renal failure: evidence for a postreceptor defect. J Clin Invest 1996; 97: 1064-75.
    • (1996) J Clin Invest , vol.97 , pp. 1064-1075
    • Ding, H.1    Gao, X.-L.2    Hirschberg, R.3    Vadgama, J.V.4    Kopple, J.D.5
  • 22
    • 0030593939 scopus 로고    scopus 로고
    • Mechanisms of muscle wasting: The role of the ubiquitin-proteasome system
    • Mitch WE, Goldberg AL. Mechanisms of muscle wasting: The role of the ubiquitin-proteasome system. N Engl J Med 1996; 335: 1897-905.
    • (1996) N Engl J Med , vol.335 , pp. 1897-1905
    • Mitch, W.E.1    Goldberg, A.L.2
  • 23
    • 0030052841 scopus 로고    scopus 로고
    • Surface hydrophobic residues of multiubiquitin chains essential for proteolytic targeting
    • Beal R, Devereaux Q, Xia G, Rechsteiner M, Pickart C. Surface hydrophobic residues of multiubiquitin chains essential for proteolytic targeting. Proc Natl Acad Sci USA 1996; 93: 861-6.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 861-866
    • Beal, R.1    Devereaux, Q.2    Xia, G.3    Rechsteiner, M.4    Pickart, C.5
  • 24
    • 0028212481 scopus 로고
    • Metabolic acidosis stimulates muscle protein degradation by activating the ATP-dependent pathway involving ubiquitin and proteasomes
    • Mitch WE, Medina R, Greiber S, May RC, England BK, Price SR, Bailey JL and Goldberg AL. Metabolic acidosis stimulates muscle protein degradation by activating the ATP-dependent pathway involving ubiquitin and proteasomes. J Clin Invest 1994; 93: 2127-33.
    • (1994) J Clin Invest , vol.93 , pp. 2127-2133
    • Mitch, W.E.1    Medina, R.2    Greiber, S.3    May, R.C.4    England, B.K.5    Price, S.R.6    Bailey, J.L.7    Goldberg, A.L.8
  • 25
    • 0030009316 scopus 로고    scopus 로고
    • The acidosis of chronic renal failure activates muscle proteolysis in rats by augmenting transcription of genes encoding proteins of the ATP-dependent ubiquitin-proteasome pathway
    • Bailey JL, Wang X, England BK, Price SR, Ding X, Mitch WE. The acidosis of chronic renal failure activates muscle proteolysis in rats by augmenting transcription of genes encoding proteins of the ATP-dependent ubiquitin-proteasome pathway. J Clin Invest 1996; 97: 1447-53.
    • (1996) J Clin Invest , vol.97 , pp. 1447-1453
    • Bailey, J.L.1    Wang, X.2    England, B.K.3    Price, S.R.4    Ding, X.5    Mitch, W.E.6
  • 26
    • 0032947267 scopus 로고    scopus 로고
    • Muscle protein breakdown and the critical role of the ubiquitin-proteasome pathway in normal and disease states
    • Lecker SH, Solomon V, Mitch WE, Goldberg AL. Muscle protein breakdown and the critical role of the ubiquitin-proteasome pathway in normal and disease states. J Nutr 1999; 129: S227-37.
    • (1999) J Nutr , vol.129
    • Lecker, S.H.1    Solomon, V.2    Mitch, W.E.3    Goldberg, A.L.4
  • 27
    • 0027972943 scopus 로고
    • Acidosis and glucocorticoids concomitantly increase ubiquitin and proteasome subunit mRNAs in rat muscle
    • Price SR, England BK, Bailey JL, Van Vreede K, Mitch WE. Acidosis and glucocorticoids concomitantly increase ubiquitin and proteasome subunit mRNAs in rat muscle. Am J Physiol 1994; 267: C955-60.
    • (1994) Am J Physiol , vol.267
    • Price, S.R.1    England, B.K.2    Bailey, J.L.3    Van Vreede, K.4    Mitch, W.E.5
  • 28
    • 0033390774 scopus 로고    scopus 로고
    • Glucocorticoids and acidification independently increase transcription of branched-chain ketoacid dehydrogenase (BCKAD)
    • Price SR, Wang X. Glucocorticoids and acidification independently increase transcription of branched-chain ketoacid dehydrogenase (BCKAD). Miner Electrolyte Metab 1999; 25: 224-7.
    • (1999) Miner Electrolyte Metab , vol.25 , pp. 224-227
    • Price, S.R.1    Wang, X.2
  • 29
    • 0025310944 scopus 로고
    • Plasma and muscle free amino acids in maintenance hemodialysis patients without protein malnutrition
    • Bergstrom J, Alvestrand A, Furst P. Plasma and muscle free amino acids in maintenance hemodialysis patients without protein malnutrition. Kidney Int 1990; 38: 108-14.
    • (1990) Kidney Int , vol.38 , pp. 108-114
    • Bergstrom, J.1    Alvestrand, A.2    Furst, P.3
  • 30
    • 1642624100 scopus 로고
    • Skeletal muscle protein synthesis and degradation in patients with chronic uremia: The influence of metabolic acidosis
    • Garibotto G, Russo R, Sofia A, et al. Skeletal muscle protein synthesis and degradation in patients with chronic uremia: The influence of metabolic acidosis. J Clin Invest 1987; 79: 1099-103.
    • (1987) J Clin Invest , vol.79 , pp. 1099-1103
    • Garibotto, G.1    Russo, R.2    Sofia, A.3
  • 31
    • 0027249311 scopus 로고
    • Correction of acidosis in humans with CRF decreases protein degradation and amino acid oxidation
    • Reaich D, Channon SM, Scrimgeour CM, et al. Correction of acidosis in humans with CRF decreases protein degradation and amino acid oxidation. Am J Physiol 1993; 265: E230-5.
    • (1993) Am J Physiol , vol.265
    • Reaich, D.1    Channon, S.M.2    Scrimgeour, C.M.3
  • 33
    • 0028231160 scopus 로고
    • Correction of metabolic acidosis and the protein catabolic rate in PD patients
    • Stein A, Baker F, Larratt C, et al. Correction of metabolic acidosis and the protein catabolic rate in PD patients. Perit Dial Int 1994; 14: 187-8.
    • (1994) Perit Dial Int , vol.14 , pp. 187-188
    • Stein, A.1    Baker, F.2    Larratt, C.3
  • 34
    • 0029792437 scopus 로고    scopus 로고
    • Serum bicarbonate is an independent determinant of protein catabolic rate in chronic hemodialysis
    • Bastani B, McNeely M, Schmitz PG. Serum bicarbonate is an independent determinant of protein catabolic rate in chronic hemodialysis. Am J Nephrol 1996; 16: 382-5.
    • (1996) Am J Nephrol , vol.16 , pp. 382-385
    • Bastani, B.1    McNeely, M.2    Schmitz, P.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.