Insulin sensitivity in hypertensive Type 2 diabetic patients after 1 and 19 days' treatment with trandolapril

Diabetic Medicine

Volumn 17, Issue 2, 2000, Pages 134-140

  New, John P ^a,b   Bilous, R W ^a   Walker, M ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b HOPE HOSPITAL   (United Kingdom)

Author keywords

Angiotensin converting enzyme inhibition; Hypertension; Insulin sensitivity; Type 2 diabetes mellitus

Indexed keywords

CHOLESTEROL; TRANDOLAPRIL; TRIACYLGLYCEROL;

ADULT; ARTICLE; CHOLESTEROL BLOOD LEVEL; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG BLOOD LEVEL; DRUG EFFECT; FEMALE; GLUCOSE TRANSPORT; HUMAN; HYPERTENSION; INSULIN SENSITIVITY; LIPID COMPOSITION; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; RANDOMIZED CONTROLLED TRIAL; TRIACYLGLYCEROL BLOOD LEVEL;

ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANTIHYPERTENSIVE AGENTS; BLOOD GLUCOSE; BLOOD PRESSURE; BODY MASS INDEX; C-PEPTIDE; DIABETES MELLITUS, TYPE 2; DOUBLE-BLIND METHOD; FEMALE; GLUCOSE CLAMP TECHNIQUE; HUMANS; HYPERTENSION; INDOLES; INSULIN; LIPIDS; MALE; MIDDLE AGED; PLACEBOS;

EID: 0034057595     PISSN: 07423071     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1464-5491.2000.00235.x     Document Type: Article

References (35)

1. 1 Ferrannini E, Buzzigoli G, Bonadonna R, Giorico MA, Oleggini M, Graziadei L et al. Insulin resistance in essential hypertension. N Engl J Med 1987; 317: 350-357.
2. 2 Ferrannini E, Galvan A. Hyperinsulinaemia, insulin resistance, and blood pressure. Hypertension Res 1992; 15: 67-75.
3. 3 Shen D, Shieh S, Fuh M, Wu D, Chen Y, Reaven G. Resistance to insulin-stimulated glucose uptake in patients with hypertension. J Clin Endocrinol Metabolism 1988; 66: 580-583.
4. 4 Reaven GM. Banting lecture 1988. Role of insulin resistance in human disease. Diabetes 1988; 37: 1595-1607.
5. 5 Fuller JH. Epidemiology of hypertension associated with diabetes mellitus. Hypertension 1985; 7: 3-7.
6. 6 Pollare T, Lithell H, Berne C. A comparison of the effects of hydrochlorothiazide and captopril on glucose and lipid metabolism in patients with hypertension. N Engl J Med 1989; 321: 868-873.
7. 7 Kodama J, Katayama S, Tanaka K, Itabashi A, Kawazu S, Ishii J. Effect of captopril on glucose concentration: possible role of augmented postprandial forearm blood flow. Diabetes Care 1990; 13: 1109-1111.
8. 8 Torlone E, Rambotti AM, Perriello G, Botto G, Santeusanio F, Brunetti P et al. ACE-inhibition increases hepatic and extrahepatic sensitivity to insulin in patients with type 2 (non-insulin-dependent) diabetes mellitus and arterial hypertension. Diabetologia 1991; 34: 119-125.
9. 9 Torlone E, Britta M, Rambotti A, Periello G, Botta G, Santeusanio F et al. Improved insulin action and glycaemic control after long-term angiotensin-converting enzyme inhibition in subjects with arterial hypertension and type II diabetes. Diabetes Care 1993; 16: 1347-1355.
10. 10 Moore MP, Elliott TW, Nicholls MG. Hormonal and metabolic effects of enalapril treatment in hypertensive subjects with NIDDM. Diabetes Care 1988; 11: 397-401.
11. 11 Seefeldt T, Orskov L, Mengel A, Rasmussen O, Pedersen MM, Moller N et al. Lack of effects of angiotensin-converting enzyme (ACE)-inhibitors on glucose metabolism in type I diabetes. Diabet Med 1990; 7: 700-7004.
12. 12 Seghieri G, Yin W, Boni C, Sanna G, Anichini R, Bartolomei G et al. Effect of chronic ACE inhibition on glucose tolerance and insulin sensitivity in hypertensive type II diabetic patients. Diabetic Med 1992; 9: 732-738.
13. 13 Bak J, Gerdes L, Sorensen N, Pedersen O. Effects of perindopril on insulin sensitivity and plasma lipid profile in hypertensive non-insulin-dependent diabetic patients. Am J Med 1992; 92: 69-72.
14. 14 Hother Nielsen O, Beck Nielsen H. On the determination of basal glucose production rate in patients with type 2 (non-insulin-dependent) diabetes mellitus using primed-continuous 3-3H-glucose infusion. Diabetologia 1990; 33: 603-610.
15. 15 Levy JC, Brown G, Matthews DR, Turner RC. Hepatic glucose output in humans measured with labelled glucose to reduce negative errors. Am J Physiol 1989; 257: E531-540.
16. 16 Wolfe R. Non-Steady State Kinetics. New York: Liss, 1984.
17. 17 Acheson R. Blood pressure in a national sample of US adults: Percentile distribution by age, sex and race. Int J Epidemiology 1973; 2: 293-301.
18. 18 Fulcher GR, Farrer M, Walker M, Rodham D, Clayton B, Alberti KM. A comparison of measurements of lean body mass derived by bioelectrical impedance, skinfold thickness and total body potassium. A study in obese and non-obese normal subjects. Scand J Clin Lab Invest 1991; 51: 245-253.
19. 19 Abumrad N, Rabin D, Diamond M, Lacy W. Use of a heated superficial hand vein as an alternative site for the measurement of amino acid concentrations and for the study of glucose and alanine kinetics in man. Metabolism 1981; 30: 936-940.
20. 20 Merilainen P. Metabolic monitor. Int J Clin Monit Comput 1987; 4: 167-177.
21. 21 Soeldner JS, Slone D. Critical variables in the radioimmunoassay of serum insulin using the double antibody technique. Diabetes 1965; 14: 771-779.
22. 22 Heding LG. Radioimmunological determination of human C-peptide in serum. Diabetologia 1975; 11: 541-548.
23. 23 Harrison J, Hodson AW, Skillen AW, Stappenbeck R, Agius L, Alberti KG. Blood glucose, lactate, pyruvate, glycerol, 3-hydroxy-butyrate and acetoacetate measurements in man using a centrifugal analyser with a fluorimetric attachment. J Clin Chem Clin Biochem 1988; 26: 141-146.
24. 24 Knox D, Jones D. Automated enzymatic determination of plasma free fatty acids by centrifugal analysis. J Automatic Chem 1984; 6: 152-154.
25. 25 Wooton IDP. The Kjeldhal method for serum proteins. In Microanalysis in Medical Biochemistry, 5th Edition. Churchill-Livingstone, 1977; 153-154.
26. 26 Somogyi M. Determination of blood sugar. J Biol Chem 1945; 160: 69-73.
27. 27 Steele R. Influences of glucose loading and of injected insulin on hepatic glucose output. Ann NY Acad Sci 1959; 82: 420-430.
28. 28 Ader M, Bergman RN. Insulin sensitivity in the intact organism. Baillieres Clin Endocrinol Metab 1987; 1: 879-910.
29. 29 Bergman RN, Finegood DT, Ader M. Assessment of insulin sensitivity in vivo. Endocr Rev 1985; 6: 45-86.
30. 30 DeFronzo RA, Tobin JD, Andres R. Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol 1979; 237: E214-223.
31. 31 Frayn KN. Calculation of substrate oxidation rates in vivo from gaseous exchange. J Appl Physiol 1983; 55: 628-634.
32. 32 Allan S, Leonard R. Captopril enalapril and blood glucose. Lancet 1986; i: 1035.
33. 33 Rett K, Wicklmayer M, Dietze G. Hypoglycaemia in hypertensive patients treated with sulphonylureas, biguanides and captopril. N Engl J Med 1988; 319: 1609.
34. 34 Herings RM, de Boer A, Stricker BH, Leutkens HG, Porsius A. Hypoglycaemia associated with use of inhibitors of angiotensin converting enzyme. Lancet 1995; 345: 1195-1198.
35. 35 Gaillard C, Leeuw P. Clinical experiences with trandolapril. Am Heart J 1993; 25: 1536-1541.