Molecular mechanisms for the growth factor action of gastrin

Journal of Gastroenterology

Volumn 35, Issue SUPPL. 12, 2000, Pages 57-64

  Todisco, Andrea ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

C fos; CCK(B) receptor; Cellular proliferation; Early response genes; ERKs; MAPK; Protein kinases; Transcriptional regulation

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; CHOLECYSTOKININ B RECEPTOR ANTAGONIST; CHOLECYSTOKININ RECEPTOR; DNA; GASTRIN; GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; PEPTIDE HORMONE; PROTEIN C FOS; PROTEIN KINASE C; PROTEIN SERINE THREONINE KINASE; RAF PROTEIN; RHO FACTOR;

ANIMAL CELL; CELL PROLIFERATION; CLOSTRIDIUM BOTULINUM; CONFERENCE PAPER; CONTROLLED STUDY; GENETIC TRANSCRIPTION; HORMONE ACTION; MOLECULAR DYNAMICS; NONHUMAN; ONCOGENE C FOS; PANCREAS CELL; PRIORITY JOURNAL; RAT; SERUM RESPONSIVE ELEMENT; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

ANIMALS; CELL DIVISION; CELL TRANSFORMATION, NEOPLASTIC; GASTRINS; GASTROINTESTINAL NEOPLASMS; GENE EXPRESSION REGULATION, NEOPLASTIC; GROWTH SUBSTANCES; HUMANS; SIGNAL TRANSDUCTION;

EID: 0034056521     PISSN: 09441174     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (43)

1. Edkins JS. The chemical mechanism of gastric secretion. J Physiol (Lond) 1906;34:133-44.
2. Johnson LR. Gastrointestinal hormones and their functions. Annu Rev Physiol 1977;39:135-58.
3. Singh P, Walker JP, Townsend CM, Thompson JC. Role of gastrin and gastrin receptors on the growth of a transplantable mouse colon carcinoma (MC-26) in BALB/c mice. Cancer Res 1987;46: 1612-16.
4. Solomon TE, Morisset J, Wood JG, Bussjaeger LJ. Additive interaction of pentagastrin and secretin on pancreatic growth in rats. Gastroenterology 1987;92:429-35.
5. Brand SJ, Fuller PJ. Differential gastrin gene expression in rat gastrointestinal tract and pancreas during neonatal development. J Biol Chem 1988;263:5341-7.
6. Wang TC, Bonner-Weir S, Oates PS, Chulak MB, Simon B, Merlino GT, et al. Pancreatic gastrin stimulates islet differentiation of transforming growth factor α-induced ductular precursor cells. J Clin Invest 1993;92:1349-56.
7. Walsh JH. Role of gastrin as a trophic hormone. Digestion 1990;47:11-16.
8. Rehfeld JF. Gastrin and colorectal cancer: a never-ending dispute? Gastroenterology 1995;108:1307-10.
9. Crespo P, Xu N, Daniotti JL, Troppmair J, Rapp UR, Gutkind S. Signaling through transforming G protein-coupled receptors in NIH 3T3 cells involves c-Raf activation. J Biol Chem 1994;269: 21103-9.
10. Crespo P, Xu N, Simonds WF, Gutkind JS. Ras-dependent activation of MAP kinase pathway mediated by G-protein βγ subunits. Nature 1994;376:418-20.
11. Hill CS, Treisman R. Transcriptional regulation by extracellular signals: mechanisms and specificity. Cell 1995;80:199-211.
12. Ullrich A, Schlessinger J. Signal transduction by receptors with tyrosine kinase activity. Cell 1990;61:203-12.
13. Cobb MH, Goldsmith EJ. How MAP kinases are regulated. J Biol Chem 1995;270:14843-6.
14. Davis JR. The mitogen-activated protein kinase signal transduction pathway. J Biol Chem 1993;268:14553-6.
15. Marx JL. The fos gene as "master switch." Science 1987;237:854-6.
16. Marais R, Wynne J, Treisman R. The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain. Cell 1993;73:381-93.
17. Treisman R. Journey to the surface of the cell: Fos regulation and the SRE. EMBO J 1995;14:4905-13.
18. Janknecht R, Hunter T. Activation of the Sap-1a transcription factor by the c-Jun N-terminal kimise (JNK) mitogen-activated protein kinase. J Biol Chem 1997;272:4219-24.
19. Hill CS, Wynne J, Treisman R, The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF. Cell 1995;81:1159-70.
20. Fromm C, Coso OA, Montaner S, Xu N, Gutkind JS. The small GTP-binding protein Rho links G protein-coupled receptors and Gα12 to serum response element and to cellular transformation. Proc Natl Acad Sci USA 1997;94:10098-103.
21. MAP. Oncogene 1994;9:861-7.
22. Todisco A, Takeuchi Y, Seva C, Dickinson CJ, Yamada T. Gastrin and glycine-extended progastrin processing intermediates induce different programs of early gene activation. J Biol Chem 1995;270:28337-41.
23. Todisco A, Takeuchi Y, Yamada J, Urumov A, Stepan V, Yamada T. Molecular mechanisms for the growth factor action of gastrin. Am J Physiol 1997;273:G891-8.
24. Christophe J. Pancreatic tumoral cell line AR42J: an amphicrine model. Am J Physiol 1994;266:G963-71.
25. Yamauchi K, Holt K, Pessin JE. Phosphatidylinositol 3-kinase functions upstream of Ras and Raf in mediating insulin stimulation of c-fos transcription. J Biol Chem 1993;268:14597-600.
26. Jensen RT, Wank SA, Rowley WH, Sato S, Gardner JD. Interaction of CCK with pancreatic acinar cells. Trends Pharmacol Sci 1989;10:418-23.
27. raf-1 kinase, and mitogenesis. Cell Growth Differ 1995;6:383-93.
28. Alessi DR, Cuenda A, Cohen P, Dudley DT, Saltiel A. PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J Biol Chem 1995;270: 27489-94.
29. Seva C, Dickinson CJ, Yamada T. Growth-promoting effects of glycine-extended progastrin. Science 1994;265:410-12.
30. Stepan VM, Tatewaki M, Matsushima M, Dickinson CJ, Del Valle J, Todisco A. Gastrin induces c-fos gene transcription via multiple signaling pathways. Am J Physiol 1999;276:G415-24.
31. Gilman M. The c-fos serum response element responds to protein kinase C-dependent and -independent signals but not to cyclic AMP. Genes Dev 1988;2:394-402.
32. Graham R, Gilman M. Distinct protein targets for signals acting at the c-fos serum response element. Science 1991;251:189-92.
33. Karin M. The regulation of AP-1 activity by mitogen-activated protein kinases. J Biol Chem 1995;270:16483-6.
34. Herman W, Simonson S. Nuclear signaling by endothelin-1. J Biol Chem 1995;270:11654-41.
35. Simonson M, Wang Y, Herman W. Nuclear signaling by endothelin-1 requires Src protein-tyrosine kinases. J Biol Chem 1996;271:77-82.
36. Denhardt DT. Signal-transducing protein phoshorylation cascades mediated by Ras/Rho proteins in the mammalian cell: the potential for multiplex signaling. Biochem J 1996;318:729-47.
37. Haubruck H, McCormick F. Ras p21: effects and regulation. Biochim Biophys Acta 1991;1072:215-29.
38. Ridley AJ, Hall A. The small GTP-binding protein rho regulates the assembly of focal adhesion and actin stress fibers in response to growth factors. Cell 1992;70:389-99.
39. Ridley AJ, Paterson HF, Johnston CL, Dickmann D. The small GTP-binding protein rac regulates growth factor-induced membrane ruffling. Cell 1992;70:401-10.
40. Minden A, Lin A, Claret F-X, Abo A, Karin M. Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases rac and Cdc42Hs. Cell 1995;81: 1147-57.
41. Morii N, Narumiya S. Preparation of native and recombinant Clostridium botulinum C3 ADP-ribosyltransferase and identification of Rho proteins by ADP-ribosylation. Methods Enzymol 1995;256:196-206.
42. Hocker M, Henihan RJ, Rosewicz S, Riechen E-O, Zhang Z, Koh TJ, et al. Gastrin and phorbol 12-myristate 13-acetate regulate the human histidine decarboxylase promoter through Raf-dependent activation of extracellular signal-regulated kinase-related signaling pathways in gastric cancer cells. J Biol Chem 1997;272:27015-24.
43. 2+ and protein kinase C-dependent mechanisms involved in gastrin-induced Shc/Grb2 complex formation and P44-mitogen-activated protein kinase activation. Biochem J 1997;325:383-9.