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Volumn 333, Issue 4, 2000, Pages 87-92

Naphthazarin derivatives (VI): Synthesis, inhibitory effect on DNA topoisomerase-I and antiproliferative activity of 2- or 6-(1-oxyiminoalkyl)- 5,8-dimethoxy-1,4-naphthoquinones

(7) Song, Gyu Yong a Kim, Yong a You, Young Jae a Cho, Hoon b Kim, Sung Hoon c Sok, Dai Eun a Ahn, Byung Zun a

a Chungnam National University (South Korea)

b Kuhnil Pharmaceutical Co LTD (South Korea)

c Kyung Hee University (South Korea)

Author keywords

2 or 6 substituted naphthazarins; Antiproliferative activity; DNA topoisomerase 1 inhibition; Structure activity

Indexed keywords

1,4 NAPHTHOQUINONE DERIVATIVE; ANTINEOPLASTIC AGENT; DNA TOPOISOMERASE INHIBITOR; NAPHTHAZARIN;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; LEUKEMIA L 1210; MOUSE; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTINEOPLASTIC AGENTS; DNA TOPOISOMERASES, TYPE I; INHIBITORY CONCENTRATION 50; LEUKEMIA L1210; MICE; NAPHTHOQUINONES; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 0034056428 PISSN: 03656233 EISSN: None Source Type: Journal
DOI: 10.1002/(SICI)1521-4184(20004)333:4<87::AID-ARDP87>3.0.CO;2-1 Document Type: Article

Times cited : (54)

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