Differential response to transforming growth factor (TGF)-α and fibroblast growth factor (FGF) in human renal cell carcinomas of the clear cell and papillary types

European Journal of Cancer

Volumn 36, Issue 7, 2000, Pages 932-941

  Ramp, U ^a   Reinecke, P ^a   Gabbert, H E ^a   Gerharz, C D ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

FGF; Human RCC; Signal transduction pathways; TGF

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 1; FIBROBLAST GROWTH FACTOR 2; FIBROBLAST GROWTH FACTOR RECEPTOR; TRANSFORMING GROWTH FACTOR ALPHA;

ARTICLE; CARCINOMA CELL; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; KIDNEY CARCINOMA; KIDNEY PAPILLA; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

ADENOCARCINOMA, CLEAR CELL; ADENOCARCINOMA, PAPILLARY; BLOTTING, NORTHERN; CARCINOMA, RENAL CELL; FIBROBLAST GROWTH FACTORS; FLOW CYTOMETRY; HUMANS; IMMUNOHISTOCHEMISTRY; KIDNEY NEOPLASMS; RECEPTORS, FIBROBLAST GROWTH FACTOR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSFORMING GROWTH FACTOR ALPHA; TUMOR CELLS, CULTURED;

EID: 0034055006     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-8049(00)00030-7     Document Type: Article

References (33)

1. Mostofi F.K. Histological Typing of Kidney Tumours. International Histologic Classification of Tumors. 1981;World Health Organization, Geneva.
2. Thoenes W., Störkel S., Rumpelt H.J. Histopathology and classification of renal cell tumors (adenomas, oncocytomas and carcinomas). Path. Res. Pract. 181:1986;125-143.
3. Störkel S., van den Berg E. Morphological classification of renal cancer. World J. Urol. 13:1995;153-158.
4. Pitz S., Moll R., Störkel S., Thoenes W. Expression of intermediate filament proteins in subtypes of renal cell carcinomas and in renal oncocytomas. Lab. Invest. 6:1987;642-653.
5. Beham A., Ratschek M., Zatloukal K., Schmid C., Denk H. Distribution of cytokeratins, vimentin and desmoplakins in normal renal tissue, renal cell carcinomas and onkocytoma as revealed by immunofluorescence microscopy. Virchows. Arch. A Pathol. Anat. Histopathol. 421:1992;209-215.
6. van den Berg E., van der Hout A.H., Oosterhuis J.W.et al. Cytogenetic analysis of epithelial renal-cell tumors. relationship with a new histopathological classification Int. J. Cancer. 55:1993;223-227.
7. van der Hout A.H., van den Berg E., van der Vlies P.et al. Loss of heterozygosity at the short arm of chromosome 3 in renal-cell cancer correlates with the cytological tumour type. Int. J. Cancer. 53:1993;353-357.
8. Kovacs G. The value of molecular genetic analysis in the diagnosis and prognosis of renal cell tumours. World J. Urol. 12:1994;64-68.
9. Markovic-Lipkovski J., Brasanac D., Todorovic V., Muller C.A., Muller G.A. Immunomorphological characteristics of renal cell carcinoma. Histol. Histopathol. 10:1995;651-659.
10. Renshaw A.A., Corless C.L. Papillary renal cell carcinoma. Am. J. Surg. Pathol. 19:1995;842-849.
11. Gerharz C.D., Hildebrandt B., Moll R.et al. Chromophilic renal cell carcinoma. cytomorphological and cytogenetic characterization of four permanent cell lines Br. J. Cancer. 74:1996;1605-1614.
12. Amin M.B., Corless C.L., Renshaw A.A., Tickoo S.K., Kubus J., Schultz D.S. Papillary (chromophil) renal cell carcinoma. histomorphological characteristics and evaluation of conventional pathologic prognostic parameters in 62 cases Am. J. Surg. Pathol. 21:1997;621-635.
13. van den Berg E., Dijkhuizen T., Oosterhuis J.W., van Kessel A.G., de Jong B., Störkel S. Cytogenetic classification of renal cell cancer. Cancer Genet. Cytogenet. 95:1997;103-107.
14. Ramp U., Jaquet K., Reinecke P., Nitsch T., Gabbert H.E., Gerharz C.D. Acquisition of TGF-beta1 resistance. an important progression factor in human renal cell carcinoma Lab. Invest. 76:1997;739-749.
15. Gomella L.G., Sargent E.R., Wade T.P., Anglard P., Linehan W.M., Kasid A. Expression of transforming growth factor alpha in normal human adult kidney and enhanced expression of transforming growth factors alpha and beta1 in renal cell carcinoma. Cancer Res. 49:1989;6972-6975.
16. Sargent E.R., Gomella L.G., Belldegrun A., Linehan W.M., Kasid A. Epidermal growth factor gene expression in normal human kidney and renal cell carcinoma. J. Urol. 142:1989;1364-1368.
17. Petrides P.E., Bock S., Bovens J., Hofmann R., Jakse G. Modulation of pro-epidermal growth factor, pro-transforming growth factor alpha and epidermal growth factor receptor gene expression in human renal carcinomas. Cancer Res. 50:1990;3934-3939.
18. Ramp U., Jaquet K., Reinecke P.et al. Functional intactness of stimulatory and inhibitory autocrine loops in human renal cell carcinoma cell lines of the clear cell type. J. Urol. 157:1997;2345-2350.
19. Biard A., Böhlen P. Fibroblast growth factors. Sporn M.B., Roberts A.B. Peptide growth factors and their receptors. 1990;369-418 Springer, Berlin, Heidelberg, New York.
20. Nanus D.M., Schmitz-Dräger B.J., Motzer R.J.et al. Expression of basic fibroblast growth factor in primary human renal tumors. correlation with poor survival J. Natl. Cancer Inst. 85:1993;1597-1599.
21. Emoto A., Nakagawa M., Wakabayashi Y., Hanada T., Naito S., Nomura Y. Induction of tubulogenesis of microvascular endothelial cells by basic fibroblast growth factor from human SN12C renal cancer cells. J. Urol. 57:1997;699-703.
22. Yoshimura K., Eto H., Miyake H., Hara I., Arakawa S., Kamidono S. Messenger ribonucleic acids for fibroblast growth factors and their receptors in bladder and renal cell carcinoma cell lines. Cancer Lett. 103:1996;91-97.
23. Fujimoto K., Ichimori Y., Yamaguchi H.et al. Basic fibroblast growth factor as a candidate tumor marker for renal cell carcinoma. Jpn J. Cancer Res. 86:1995;182-186.
24. Mydlo J.H., Zajac J., Macchia R.J. Conditioned media from a renal carcinoma cell line demonstrates the presence of basic fibroblast growth factor. J. Urol. 150:1993;997-1001.
25. Gerharz C.D., Moll R., Störkel S., Ramp U., Thoenes W., Gabbert H.E. Ultrastructural appearance and cytoskeletal architecture of the clear, chromophilic and chromophobe cell variants of human renal cell carcinoma in vitro. Am. J. Pathol. 142:1993;851-859.
26. Gerharz C.D., Ramp U., Olert J.et al. Cytomorphological, cytogenetic, and molecular biological characterization of four new human renal carcinoma cell lines of the clear cell type. Virchows Arch. B. 424:1994;403-409.
27. Störkel S., Thoenes W., Jacobi G.H., Lippold R. Prognostic parameters in renal cell carcinoma - a new approach. Eur. Urol. 16:1989;416-422.
28. Chirgwin J.M., Przybyla A.E., MacDonald R.J., Rutter W.J. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry. 18:1979;5294-5299.
29. Eguchi J., Nomata K., Kanda S.et al. Gene expression and immunohistochemical localization of basic fibroblast growth factor in renal cell carcinoma. Biochem. Biophys. Res. Communications. 183:1992;937-944.
30. Partanen J., Mäkelä T.P., Eerola E.et al. FGFR-4, a novel acidic fibroblast growth factor receptor with a distinct expression pattern. EMBO J. 10:1991;1347-1354.
31. Daniel T. Peptide growth factors and the kidney. Seldin D.W., Giebisch G. The Kidney. Physiology and Pathophysiology:1992;3135-3155 Raven Press, New York.
32. Goodyer P.R., Cybulsky A., Goodyer C. Expression of the epidermal growth factor receptor in fetal kidney. Pediatr. Nephrol. 7:1993;612-616.
33. Carpenter G., Wahl M.I. The epidermal growth factor family. Sporn M.B., Roberts A.B. Peptide Growth Factors and their Receptors. 1990;69-171 Springer, Berlin.