메뉴 건너뛰기




Volumn 108, Issue 2, 2000, Pages 72-75

Lack of germline mutations in the preproglucagon gene region coding for glucagon-like peptide 1 in Type 2 diabetic (NIDDM) patients

Author keywords

Gastric inhibitory polypeptide (GIP); Genetics; Glucagon like peptide 1 (GLP 1); Incretin; Insulin secretion; Type 2 diabetes

Indexed keywords

DNA; GLUCAGON LIKE PEPTIDE 1; PREPROGLUCAGON; RECEPTOR;

EID: 0034054153     PISSN: 09477349     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2000-5798     Document Type: Article
Times cited : (3)

References (27)
  • 1
  • 2
    • 0026638575 scopus 로고
    • Mapping diabetes-susceptibility genes. Lessons learned from search for DNA marker for maturity-onset diabetes of the young
    • Cox NJ, Xiang K-S, Fajans S: Bell GI: Mapping diabetes-susceptibility genes. Lessons learned from search for DNA marker for maturity-onset diabetes of the young. Diabetes 41: 401-407, 1992
    • (1992) Diabetes , vol.41 , pp. 401-407
    • Cox, N.J.1    Xiang, K.-S.2    Fajans, S.3    Bell, G.I.4
  • 3
    • 0029584116 scopus 로고
    • Regulation of islet hormone gene expression by incretin hormones
    • Fehmann HC, Gherzi R, Göke B: Regulation of islet hormone gene expression by incretin hormones. Exp Clin Endocrinol Diabetes 103 Suppl 2: 56-65, 1995
    • (1995) Exp Clin Endocrinol Diabetes , vol.103 , Issue.2 SUPPL. , pp. 56-65
    • Fehmann, H.C.1    Gherzi, R.2    Göke, B.3
  • 4
    • 0026596851 scopus 로고
    • Antidiabetogenic effect of glucagon-like peptide-1 (7-36)amide in normal subjects and patients with diabetes mellitus
    • Gutniak MK, Holst JJ, Ørskov C, Åhren B, Efendic S: Antidiabetogenic effect of glucagon-like peptide-1 (7-36)amide in normal subjects and patients with diabetes mellitus. N Engl J Med. 326: 1316-1322, 1992
    • (1992) N Engl J Med , vol.326 , pp. 1316-1322
    • Gutniak, M.K.1    Holst, J.J.2    Ørskov, C.3    Åhren, B.4    Efendic, S.5
  • 5
    • 0023104829 scopus 로고
    • Truncated glucagon-like peptide 1, an insulin-releasing hormone from the distal gut
    • Holst JJ, Orskov C, Vagn-Nielsen O, Schwartz TW: Truncated glucagon-like peptide 1, an insulin-releasing hormone from the distal gut. FEBS Letters. 211: 169-174, 1987
    • (1987) FEBS Letters , vol.211 , pp. 169-174
    • Holst, J.J.1    Orskov, C.2    Vagn-Nielsen, O.3    Schwartz, T.W.4
  • 6
    • 0028883257 scopus 로고
    • Reduction of the incretin effect in rats by the glucagon-like peptide 1 receptor antagonist exendin (9-39) amide
    • Kolligs F, Fehmann HC, Göke R, Göke B: Reduction of the incretin effect in rats by the glucagon-like peptide 1 receptor antagonist exendin (9-39) amide. Diabetes 44: 16-19, 1995
    • (1995) Diabetes , vol.44 , pp. 16-19
    • Kolligs, F.1    Fehmann, H.C.2    Göke, R.3    Göke, B.4
  • 7
    • 0024836493 scopus 로고
    • Glucagonostatic and insulinotropic action of glucagonlike peptide I-(7-36)-amide
    • Komatsu R, Matsuyama T, Namba M et al.: Glucagonostatic and insulinotropic action of glucagonlike peptide I-(7-36)-amide. Diabetes 38: 902-905, 1989
    • (1989) Diabetes , vol.38 , pp. 902-905
    • Komatsu, R.1    Matsuyama, T.2    Namba, M.3
  • 8
    • 0023638829 scopus 로고
    • Glucagon-like peptide-1 [7-36]: A physiological incretin in man
    • Kreymann B, Williams G, Ghatei MA, Bloom SR: Glucagon-like peptide-1 [7-36]: a physiological incretin in man. Lancet 2: 1300-1304, 1987
    • (1987) Lancet , vol.2 , pp. 1300-1304
    • Kreymann, B.1    Williams, G.2    Ghatei, M.A.3    Bloom, S.R.4
  • 9
    • 0023107555 scopus 로고
    • Insulinotropin: Glucagon-like peptide I (7-37) co-encoded in the glucagon gene is a potent stimulator of insulin release in the perfused rat pancreas
    • Mojsov S, Weir GC, Habener JF: Insulinotropin: glucagon-like peptide I (7-37) co-encoded in the glucagon gene is a potent stimulator of insulin release in the perfused rat pancreas. J Clin Invest 79: 616-619, 1987
    • (1987) J Clin Invest , vol.79 , pp. 616-619
    • Mojsov, S.1    Weir, G.C.2    Habener, J.F.3
  • 10
    • 0026542396 scopus 로고
    • Insulinotropic action of glucagon-like peptide 1 (7-37) in diabetic and non-diabetic subjects
    • Nathan DM, Schreiber E, Fogel H, Mojsov S, Habener JF: Insulinotropic action of glucagon-like peptide 1 (7-37) in diabetic and non-diabetic subjects. Diabetes Care 15: 270-276, 1992
    • (1992) Diabetes Care , vol.15 , pp. 270-276
    • Nathan, D.M.1    Schreiber, E.2    Fogel, H.3    Mojsov, S.4    Habener, J.F.5
  • 11
    • 0027419106 scopus 로고
    • Additive insulinotropic effects of exogenous synthetic human gastric inhibitory polypeptide and glucagon-like peptide-1-(7-36) amide infused at near-physiological insulinotropic hormone and glucose concentrations
    • Nauck MA, Bartels E, Ørskov C, Ebert R, Creutzfeldt W: Additive insulinotropic effects of exogenous synthetic human gastric inhibitory polypeptide and glucagon-like peptide-1-(7-36) amide infused at near-physiological insulinotropic hormone and glucose concentrations. J Clin Endocrinol Metab 76: 912-917, 1993a
    • (1993) J Clin Endocrinol Metab , vol.76 , pp. 912-917
    • Nauck, M.A.1    Bartels, E.2    Ørskov, C.3    Ebert, R.4    Creutzfeldt, W.5
  • 12
    • 0027391607 scopus 로고
    • Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus
    • Nauck MA, Heimesaat MM, Ørskov C, Holst JJ, Ebert R, Creutzfeldt W: Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus. J Clin Invest 91: 301-307, 1993b
    • (1993) J Clin Invest , vol.91 , pp. 301-307
    • Nauck, M.A.1    Heimesaat, M.M.2    Ørskov, C.3    Holst, J.J.4    Ebert, R.5    Creutzfeldt, W.6
  • 13
    • 0027248866 scopus 로고
    • Normalization of fasting hyperglycaemia by exogenous glucagon-like peptide 1 (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients
    • Nauck MA, Kleine N, Ørskov C, Holst JJ, Willms B, Creutzfeldt W: Normalization of fasting hyperglycaemia by exogenous glucagon-like peptide 1 (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients. Diabetologia 36: 741-744, 1993c
    • (1993) Diabetologia , vol.36 , pp. 741-744
    • Nauck, M.A.1    Kleine, N.2    Ørskov, C.3    Holst, J.J.4    Willms, B.5    Creutzfeldt, W.6
  • 14
    • 0030667056 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 inhibition of gastric emptying outweighs its insulinotropic effects in healthy humans
    • Nauck MA, Niedereichholz U, Ettler R et al.: Glucagon-like peptide 1 inhibition of gastric emptying outweighs its insulinotropic effects in healthy humans. Am J Physiol 273: E981-988, 1997
    • (1997) Am J Physiol , vol.273
    • Nauck, M.A.1    Niedereichholz, U.2    Ettler, R.3
  • 15
    • 0026659679 scopus 로고
    • Glucagon-like peptide-1, a new hormone of the entero-insular axis
    • Ørskov C: Glucagon-like peptide-1, a new hormone of the entero-insular axis. Diabetologia 35: 701-711, 1992
    • (1992) Diabetologia , vol.35 , pp. 701-711
    • Ørskov, C.1
  • 16
    • 0023758530 scopus 로고
    • Effect of truncated glucagon-like peptide-1 [proglucagon-(78-107) amide] on endocrine secretion from pig pancreas, antrum, and nonantral stomach
    • Ørskov C, Holst JJ, Nielsen OV: Effect of truncated glucagon-like peptide-1 [proglucagon-(78-107) amide] on endocrine secretion from pig pancreas, antrum, and nonantral stomach. Endocrinology 123: 2009-2013, 1988
    • (1988) Endocrinology , vol.123 , pp. 2009-2013
    • Ørskov, C.1    Holst, J.J.2    Nielsen, O.V.3
  • 17
    • 0026027919 scopus 로고
    • Proglucagon products in plasma of noninsulin-dependent diabetics and nondiabetic controls in the fasting state and after oral glucose and intravenous arginine
    • Ørskov C, Jeppesen J, Madsbad S, Holst JJ: Proglucagon products in plasma of noninsulin-dependent diabetics and nondiabetic controls in the fasting state and after oral glucose and intravenous arginine. J Clin Invest 87: 415-423, 1991
    • (1991) J Clin Invest , vol.87 , pp. 415-423
    • Ørskov, C.1    Jeppesen, J.2    Madsbad, S.3    Holst, J.J.4
  • 18
    • 0022971804 scopus 로고
    • Glucagon-like peptides GLP-1 and GLP-2, predicted products of the glucagon gene, are secreted separately from pig small intestine but not pancreas
    • Ørskov C, Knuhtsen S, Baldissera FG, Poulsen SS, Nielsen OV, Holst JJ: Glucagon-like peptides GLP-1 and GLP-2, predicted products of the glucagon gene, are secreted separately from pig small intestine but not pancreas. Endocrinology 119: 1467-1475, 1986
    • (1986) Endocrinology , vol.119 , pp. 1467-1475
    • Ørskov, C.1    Knuhtsen, S.2    Baldissera, F.G.3    Poulsen, S.S.4    Nielsen, O.V.5    Holst, J.J.6
  • 19
    • 6744223889 scopus 로고    scopus 로고
    • Fehlen von Mutationen im Proglucagon-Exon, das für GLP-1 codiert, bei Patienten mit Typ II-Diabetes
    • Sauerwald A, Hahn S, Schmiegel W, Nauck M: Fehlen von Mutationen im Proglucagon-Exon, das für GLP-1 codiert, bei Patienten mit Typ II-Diabetes. Diabetes Stoffw. 6 (Suppl. 1): 97, 1997
    • (1997) Diabetes Stoffw , vol.6 , Issue.1 SUPPL. , pp. 97
    • Sauerwald, A.1    Hahn, S.2    Schmiegel, W.3    Nauck, M.4
  • 20
    • 0027202020 scopus 로고
    • Human glucagon-like peptide-1 receptor gene. Localization to chromosome band 6p21 by fluorescence in situ hybridization and linkage of a highly polymorphic simple tandem repeat DNA polymorphism to other markers on chromosome 6
    • Stoffel M, Espinosa Rd, Le Beau MM, Bell GI: Human glucagon-like peptide-1 receptor gene. Localization to chromosome band 6p21 by fluorescence in situ hybridization and linkage of a highly polymorphic simple tandem repeat DNA polymorphism to other markers on chromosome 6. Diabetes 42: 1215-1218, 1993
    • (1993) Diabetes , vol.42 , pp. 1215-1218
    • Stoffel, M.1    Espinosa, Rd.2    Le Beau, M.M.3    Bell, G.I.4
  • 21
    • 0028817665 scopus 로고
    • Type II diabetes: Clinical aspacts of molecular biological studies
    • Turner RC, Hattersley AT, Shaw JTE, Levy JC: Type II diabetes: Clinical aspacts of molecular biological studies. Diabetes 44: 1-10, 1995
    • (1995) Diabetes , vol.44 , pp. 1-10
    • Turner, R.C.1    Hattersley, A.T.2    Shaw, J.T.E.3    Levy, J.C.4
  • 22
    • 13344282056 scopus 로고    scopus 로고
    • A role for glucagon-like peptide-1 in the central regulation of feeding
    • Turton MD, O'Shea D, Gunn I et al.: A role for glucagon-like peptide-1 in the central regulation of feeding. Nature 379: 69-72, 1996
    • (1996) Nature , vol.379 , pp. 69-72
    • Turton, M.D.1    O'Shea, D.2    Gunn, I.3
  • 23
    • 0029898143 scopus 로고    scopus 로고
    • In vitro insulinomimetic effects of GLP-1 in liver, muscle and fat
    • Valverde I, Villanueva Penacarrillo ML: In vitro insulinomimetic effects of GLP-1 in liver, muscle and fat. Acta Physiol Scand. 157: 359-360, 1996
    • (1996) Acta Physiol Scand , vol.157 , pp. 359-360
    • Valverde, I.1    Villanueva Penacarrillo, M.L.2
  • 24
    • 0030905717 scopus 로고    scopus 로고
    • Genetics of NIDDM in France. Studies with 19 candidate genes in affected sib pairs
    • Vionnet N, Hani EH, Lesage S et al.: Genetics of NIDDM in France. Studies with 19 candidate genes in affected sib pairs. Diabetes 46: 1062-1068, 1997
    • (1997) Diabetes , vol.46 , pp. 1062-1068
    • Vionnet, N.1    Hani, E.H.2    Lesage, S.3
  • 25
    • 0025923821 scopus 로고
    • Chelex 100 as a medium for simple extraction of DNA for PCR-based typing from forensic material
    • Walsh PS, Metzger DA, Higuchi R: Chelex 100 as a medium for simple extraction of DNA for PCR-based typing from forensic material. BioTechniques 10: 506-513, 1991
    • (1991) BioTechniques , vol.10 , pp. 506-513
    • Walsh, P.S.1    Metzger, D.A.2    Higuchi, R.3
  • 27
    • 0030068620 scopus 로고    scopus 로고
    • Gastric emptying, glucose responses, and insulin secretion after a liquid test meal: Effects of exogenous glucagon-like peptide-1 (GLP-1)-(7-36) amide in type 2 (noninsulin-dependent) diabetic patients
    • Willms B, Werner J, Holst JJ, Ørskov C, Creutzfeldt W, Nauck MA: Gastric emptying, glucose responses, and insulin secretion after a liquid test meal: effects of exogenous glucagon-like peptide-1 (GLP-1)-(7-36) amide in type 2 (noninsulin-dependent) diabetic patients. J Clin Endocrinol Metab. 81: 327-332, 1996
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 327-332
    • Willms, B.1    Werner, J.2    Holst, J.J.3    Ørskov, C.4    Creutzfeldt, W.5    Nauck, M.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.