Study on pharmacokinetics of transdermal ionphoretic ibuprofen in rabbits

Chinese Pharmaceutical Journal

Volumn 35, Issue 3, 2000, Pages 189-191

  Zhang, Li ^a   Qi, Gang ^a   Zhu, Hui ^a  

^a Basic Department   (China)

Author keywords

HPLC; Ibuprofen; Pharmacokinetic parameter; Transdermal ionphoretie delivery system

Indexed keywords

IBUPROFEN;

ANIMAL EXPERIMENT; ARTICLE; BIOEQUIVALENCE; COMPARATIVE STUDY; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; IONTOPHORESIS; NONHUMAN; RABBIT; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SKIN ABSORPTION; THEORY;

EID: 0034054144     PISSN: 10012494     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. Thompson M, Anderson M. Studies of gastrointestinal blood lose during ibuprofentherapy. Rheum Phy Med, 1970, 10(Suppl): 104.
2. Holdstock DJ. Gastrointestinal bleeding: a possible asspciation with ibuprofen. Lancet, 1972,1(749):541.
3. Muktadir et al. Studies on topical dds of ibuprofen. Drug Der Ind Pharm, 1986,12(14):2521.
4. Akhter SA; Barry BW. Absorption through human skin of ibuprofen and flurbiprofen effect of dose variation, deposited drug films, occlusion and the penetration enhance N-methyl-2-pyrrolidone. J Pharm Pharmacol. 1985,37(1):27.