High sensitivity of fetal DNA in plasma compared to serum and nucleated cells using unnested PCR in maternal blood

Fetal Diagnosis and Therapy

Volumn 15, Issue 2, 2000, Pages 102-107

  Houfflin Debarge, Véronique ^a   O'Donnell, Hilary ^a   Overton, Timothy ^a   Bennett, Phillip R ^a   Fisk, Nicholas M ^a,b  

^a IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

^b QUEEN CHARLOTTE S AND CHELSEA HOSPITAL   (United Kingdom)

Author keywords

Fetal DNA; Maternal blood; Unnested polymerase chain reaction

Indexed keywords

CHLOROFORM; PHENOL;

ARTICLE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DNA DETERMINATION; FEMALE; HUMAN; MATERNAL BLOOD; MATERNAL PLASMA; MATERNAL SERUM; NORMAL HUMAN; POLYMERASE CHAIN REACTION; PREGNANCY; PRENATAL DIAGNOSIS; PRIORITY JOURNAL; SEX DIAGNOSIS;

EID: 0034054074     PISSN: 10153837     EISSN: None     Source Type: Journal    
DOI: 10.1159/000020985     Document Type: Article

References (30)

1. Overton TG, Lighten AD, Fisk NM, Bennett PR: Prenatal diagnosis by minimally invasive first trimester transcervical sampling is unreliable. Am J Obstet Gynecol 1996;175:382-387.
2. Schmorl G: Pathologisch-anatomische Untersuchungen über Puerperal-Eklampsic. Leipzig, Vogel, 1893.
3. Bianchi DW, Williams JM, Sullivan LM, Hanson FW, Klinger KW, Shuber AP: PCR quantification of fetal cells in maternal blood in normal and aneuploid pregnancies. Am J Hum Genet 1997;61:822-829.
4. Al-Mufti R, Howard C, Overton T, Holzgreve W, Gaenshirt D, Fisk N, Bennett P: Detection of fetal messenger ribonucleic acid in maternal blood to determine fetal RhD status as a strategy for noninvasive prenatal diagnosis. Am J Obstet Gynecol 1998;179:210-214.
5. Lo YMD, Corbetta N, Chamberlain PF, Rai V, Sargent IL, Redman CW, Wainscoat J: Presence of fetal DNA in maternal plasma and serum. Lancet 1997;350:485-487.
6. Leon SA, Ehrlich GE, Shapiro B, Labbate VA: Free DNA in the serum of rheumatoid arthritis patients. J Rheumatol 1977;4:139-143.
7. Leon SA, Shapiro B, Sklaroff DM, Yaros MJ: Free DNA in the serum of cancer patients and the effect of therapy. Cancer Res 1977;37:646-650.
8. Raptis L, Menard HA: Quantification and characterization of plasma DNA in normals and patients with systemic lupus erythematosus. J Clin Invest 1980;68:1391-1399.
9. Sambrook J, Fritsch EF, Maniatis T: Plasmid vectors; in Ford N (ed): Molecular Cloning: A Laboratory Manual, ed 2. Cold Spring Harbor, Cold Spring Harbor Laboratory, 1989, vol 1, pp 1-36.
10. Kogan SC, Doherty M, Gitschier J: An improved method for prenatal diagnosis of genetic diseases by analysis of amplified DNA sequences. N Engl J Med 1987;317:985-990.
11. Lo YMD, Tein MS, Lau TK, Haines CJ, Leung TN, Poon PM, Wainscoat JS, Johnson PJ, Chang AM, Hjelm NM: Quantitative analysis of fetal DNA in maternal plasma and serum: Implications for noninvasive prenatal diagnosis. Am J Hum Genet 1998;62:768-775.
12. Kao SM, Tang GC, Hsieh TT, Young KC, Wang HC, Pao CC: Analysis of peripheral blood of pregnant women for the presence of fetal Y chromosome-specific ZFY gene deoxyribonucleic acid sequences. Am J Obstet Gynecol 1992;166:1013-1019.
13. Emanuel SL, Pestka S: Amplification of specific gene products from human serum. Genet Anal Tech Appl 1993;10:144-146.
14. Anker P, Stroun M, Maurice PA: Spontaneous release of DNA by human blood lymphocytes in vitro. Cancer Res 1975;3:2375-2382.
15. Anker P, Lefort F, Vasioukhin V, Lyautey J, Lederrey C, Chen XQ, Stroun M, Mulcahy HE, Farthing MJ: K ras mutations are found in DNA extracted from the plasma of patients with colorectal cancer. Gastroenterology 1997; 112:1114-1120.
16. Shapiro B, Chakrabarty M, Cohn EM, Leon SA: Determination of circulating DNA levels in patients with benign or malignant gastrointestinal disease. Cancer 1983;51:2116-2120.
17. Bianchi DW: Fetal DNA in maternal plasma: The plot thickens and the placental barrier thins. Am J Hum Genet 1998;62:763-764.
18. Thomas MR, Williamson R, Craft I, Yazdani N, Rodeck CH: Y chromosome sequence DNA amplified from peripheral blood of woman in early pregnancy. Lancet 1994;343:413-414.
19. Martin M, Carrington M, Mann D: A method for using serum or plasma as a source of DNA for HLA typing. Hum Immunol 1992;33:108-113.
20. Fournié GK, Lulé J, Laval F: Le DNA extracellulaire joue-t-il un rôle pathogène dans le développement des glomérulonéphrites lupiques. Néphrologie 1989;10:133-137.
21. Sano H, Morimoto C: DNA isolated from DNA/anti-DNA antibody immune complexes in systemic lupus erythematosus is rich in guanine-cytosine content. J Immunol 1982; 128:1341-1345.
22. Steiman CR: Circulating DNA in systemic lupus erythematosus: Isolation and characterization. J Clin Invest 1984;73:832-841.
23. Toth T, Findlay I, Pap C, Toth-Pal E, Marton T, Nagy B, Quirke P, Papp Z: Prenatal detection of trisomy 21 and 18 from amniotic fluid by quantitative fluorescent polymerase chain reaction. J Med Genet 1998;35:126-129.
24. Leung TN, Zhang J, Lau TK, Hjelm NM, Lo YM: Maternal plasma fetal DNA as a marker for preterm labour. Lancet 1998;352:1904-1905.
25. Chua S, Wilkins T, Sargent I, Redman C: Trophoblast deportation in pre-eclamptic pregnancy. Br J Obstet Gynaecol 1991;98:973-979.
26. Holzgreve W, Ghezzi F, Di Naro E, Ganshirt D, Maymon E, Hahn S: Disturbed feto-maternal cell traffic in pre-eclampsia. Obstet Gynecol 1999;91:669-672.
27. Lo YM, Leung TN, Tein MS, Sargent IL, Zhang J, Lau TK, Haines CJ, Redman CW: Quantitative abnormalities of fetal DNA in maternal serum in preeclampsia. Clin Chem 1999;45:184-188.
28. Lo YMD, Hjelm NM, Path FRC, Fidler C, Sargent I, Murphy M, Path FRC, Chamberlain PF, Poon MK, Redman CWG, Wainscoat JS, Path FRC: Prenatal diagnosis of fetal RhD status by molecular analysis of maternal plasma. N Engl J Med 1998;339:1734-1738.
29. Faas BH, Beuling EA, Christiaens GC, von dem Borne AE, van der School CE: Detection of felal RHD-specific sequences in maternal plasma. Lancet 1998;352:1196.
30. Bischoff FZ, Nguyen DD, Marquez Do, Moise KJ Jr, Simpson JL, Elias S: Noninvasive determination of fetal RhD status using fetal DNA in maternal serum and PCR. J Soc Gynecol Investig 1999;6:64-69.