Renal vasopressin receptor expression and function in rats following spaceflight

Journal of Applied Physiology

Volumn 88, Issue 4, 2000, Pages 1316-1320

  Brooks, David P ^a   Nambi, Ponnal ^a   Laping, Nicholas J ^a   Olson, Barbara A ^a   Pullen, Mark ^a   Wade, Charles E ^b  

^a GLAXOSMITHKLINE   (United Kingdom)

^b NASA AMES RESEARCH CENTER   (United States)

Author keywords

Antidiuretic hormone; Fluid balance; Microgravity; Water metabolism

Indexed keywords

ADENYLATE CYCLASE; VASOPRESSIN; VASOPRESSIN RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FLUID BALANCE; KIDNEY; MALE; MICROGRAVITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECEPTOR BINDING; RECEPTOR DENSITY; SPACE FLIGHT; WATER METABOLISM;

EID: 0034051767     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/jappl.2000.88.4.1316     Document Type: Article

References (23)

1. Gazenko OG, Natochin YV, Ilyin YA, Ilyushko NA, Kondratiev YI, Lavrova YA, and Shakhmatova YI. Fluid-electrolyte metabolism and renal function of white rats in experiments aboard Cosmos biosatellites. Aviat Space Environ Med 55: 685-691, 1984.
2. Gazenko OG, Grigoriev AI, and Natochin YV. Water-salt homeostasis and spaceflight. Probl Kosm Biol 54: 1-238, 1986.
3. Gazenko OG, Shul'zhenko EB, Grigoriev AI, At'kov OI, and Egorov AD. Review of basic medical results of the Saliut-7-Soiuz-T 8-month manned flight. Acta Astronaut 17: 155-160, 1988.
4. Gazenko OG, Shul'zhenko YV, Grigoriev AI, At'kov OI, and Egorov AD. Medical studies during an 8-month flight on the orbital complex "Saliut-7"-"Soiuz-T." Kosm Biol Aviakosm Med 24: 9-14, 1990.
5. Gazenko OG, Grigoriev AI, and Egorov AD. Medical studies concerning the program of long-term manned spaceflight on "Saliut-7"-"Soiuz-T" orbital complex. Kosm Biol Aviakosm Med 24: 9-15, 1990.
6. Grigoriev AI, Popova IA, and Ushakov AS. Metabolic and hormonal status of crewmembers in short-term spaceflights. Aviat Space Environ Med 58: A121-A125, 1987.
7. Keil L, Evans J, Grindeland R, and Krasnov I. Pituitary oxytocin and vasopressin content of rats flown on COSMOS 2044. J Appl Physiol 73: 166S-168S, 1992.
8. Leach CS. Fluid control mechanisms in weightlessness. Aviat Space Environ Med 58: A74-A79, 1987.
9. Leach CS. Medical results from STS 1-4: analysis of body fluids Aviat Space Environ Med 54: S50-S54, 1983.
10. Leach CS, Alfrey CP, Suki WN, Leonard JI, Rambaut PC, Inners LD, Smith SM, Lane HW, and Krauhs JM. Regulation of body fluid compartments during short term spaceflight. J Appl Physiol 81: 105-106, 1996.
11. Leach CS and Rambaut PC. Biomedical responses of the Skylab crewman: an overview. In: Biomedical Results From Skylab, edited by Johnston RS and Deitlein LF. Washington, DC: National Aeronautics and Space Administration, 1977, p. 204-216.
12. Natochin YV, Kozyrevskaya GI, and Grigoriev AI. Study of water-salt metabolism and renal function in cosmonauts. Acta Astronaut 2:175-188, 1975.
13. Natochin YV, Grigoriev AI, and Serova LV. The influence of spaceflight on water-salt homeostasis in man and animals. In: Proceeding of the Third European Symposium on Life Sciences Research in Space Graz Austria 1987. Norrdwijk, Netherlands: ESA Publications Division, ESTEC, 1987, p. 259-261.
14. Natochin YV, Grigoriev A, Noskov VB, Parnova RG, Sukhanov YV, Firsov DL, and Shakhomatova EI. Mechanism of postflight decline in osmotic concentration of urine in cosmonauts. Aviat Space Environ Med 62: 1037-1043, 1991.
15. Norsk P and Epstein M. Manned spaceflight and the kidney. Am J Nephrol 11: 81-97, 1991.
16. Rowe JW, Shelton RL, Helderman JH, Vestal RE, and Robertson GL. Influence of the emetic reflex on vasopressin release in man. Kidney Int 16: 729-735, 1979.
17. Salomon Y, Londos C, and Rodbell M. A highly sensitive adenylate cylase assay. Anal Biochem 58: 541-548, 1974.
18. Vorobyov EI, Gazenko OG, Genin AM, and Egorov AD. Medical results of Saliut-6 manned spaceflights. Aviat Space Environ Med 54: S31-S40, 1983.
19. Wade CE and Keil LC. Reduction of pituitary AVP and OT contents in rats following spaceflight. Aviat Space Environ Med 69: A53-A57, 1998.
20. Wade CE and Morey-Holton E. Alteration of renal function of rats following spaceflight. Am J Physiol Regulatory Integrative Comp Physiol 275: R1058-R1065, 1998.
21. Wang YX, Edwards RM, Nambi P, Stack EJ, Pullen M, Share L, Crofton JT, and Brooks DP. Sex difference in the antidiuretic activity of vasopressin in the rat. Am J Physiol Regulatory Integrative Comp Physiol 265: R1284-R1290, 1993.
22. Watenpaugh DE and Hargens AR. The cardiovascular system in microgravity. In: Handbook of Physiology. Environmental Physiology. Bethesda, MD: Am. Physiol. Soc., 1996, sect. 4, vol. 1, chap. 29, p. 631-674.
23. Weitzman R and Kleeman CR. Water metabolism and the neurophysical hormones. In: Clinical Disorders of Fluid and Electrolyte Metabolism, edited by. Maxwell MH and Kleeman CR. New York: McGraw-Hill, 1980, p. 531-645.