메뉴 건너뛰기




Volumn 290, Issue 1, 2000, Pages 85-96

Molecular cloning and targeted deletion of PEP2 which encodes a novel aspartic proteinase from Aspergillus fumigatus

Author keywords

Aspartic proteinase; Aspergillus fumigatus; Cell wall; Fungus; PEP2; Proteinase; Vacuolar proteinase; Vacuole

Indexed keywords

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ASPARTIC PROTEINASE; ASPERGILLOSIS; ASPERGILLUS NIGER; CELL VACUOLE; CELL WALL; COMPLEMENTARY DNA; DELETION MUTAGENESIS; ENZYME ACTIVITY; FUNGAL GROWTH; GENE PROBE; MOLECULAR CLONING; PEP2 GENE; PH; PROTEINASE A; SACCHAROMYCES CEREVISIAE; SIGNAL PEPTIDE;

EID: 0034051579     PISSN: 14384221     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1438-4221(00)80111-3     Document Type: Article
Times cited : (41)

References (43)
  • 1
    • 0022753540 scopus 로고
    • PEP4 gene of Saccharomyces cerevisiae encodes proteinase A, a vacuolar enzyme required for processing of vacuolar precursors
    • Ammerer, G., Hunter, C. P., Rothman, J. H., Saari, G.C., Valls, L. A., Stevens, T. H.: PEP4 gene of Saccharomyces cerevisiae encodes proteinase A, a vacuolar enzyme required for processing of vacuolar precursors. Mol. Cell Biol. 6, 2490-2499 (1986).
    • (1986) Mol. Cell Biol. , vol.6 , pp. 2490-2499
    • Ammerer, G.1    Hunter, C.P.2    Rothman, J.H.3    Saari, G.C.4    Valls, L.A.5    Stevens, T.H.6
  • 2
    • 85012738381 scopus 로고
    • The estimation of pepsin, trypsin, papain and cathepsin with hemoglobin
    • Anson, M. L.: The estimation of pepsin, trypsin, papain and cathepsin with hemoglobin. J. Gen. Physiol. 22, 79-91 (1938).
    • (1938) J. Gen. Physiol. , vol.22 , pp. 79-91
    • Anson, M.L.1
  • 3
    • 0028673152 scopus 로고
    • Classification of peptidases
    • Barrett, A. J.: Classification of peptidases. Methods Enzymol. 244, 1-15 (1994).
    • (1994) Methods Enzymol. , vol.244 , pp. 1-15
    • Barrett, A.J.1
  • 5
    • 0014011862 scopus 로고
    • The induction and repression of nitrate reductase in the fungus Aspergillus nidulans
    • Cove, D. J.: The induction and repression of nitrate reductase in the fungus Aspergillus nidulans. Biochim. Biophys. Acta 113, 51-56 (1966).
    • (1966) Biochim. Biophys. Acta , vol.113 , pp. 51-56
    • Cove, D.J.1
  • 6
    • 0031893513 scopus 로고    scopus 로고
    • Invasive aspergillosis
    • Denning, D.W.: Invasive aspergillosis. Clin. Infect. Dis. 26, 781-805 (1998).
    • (1998) Clin. Infect. Dis. , vol.26 , pp. 781-805
    • Denning, D.W.1
  • 7
    • 0028068165 scopus 로고
    • Cloning and characterization of the pepE gene of Aspergillus niger encoding a new aspartic protease and regulation of pepE and pepC
    • Jarai, G., van den Hombergh, H., Buxton, F. P.: Cloning and characterization of the pepE gene of Aspergillus niger encoding a new aspartic protease and regulation of pepE and pepC. Gene 145, 171-178 (1994).
    • (1994) Gene , vol.145 , pp. 171-178
    • Jarai, G.1    Van Den Hombergh, H.2    Buxton, F.P.3
  • 9
    • 0027119999 scopus 로고
    • Nucleotide sequence of a genomic and a cDNA clone encoding an extracellular alkaline protease of Aspergillus fumigatus
    • Jaton-Ogay, K., Suter, M., Crameri, R., Falchetto, R., Fatih, A., Monod, M.: Nucleotide sequence of a genomic and a cDNA clone encoding an extracellular alkaline protease of Aspergillus fumigatus. FEMS Microbiol. Lett. 71, 163-168 (1992).
    • (1992) FEMS Microbiol. Lett. , vol.71 , pp. 163-168
    • Jaton-Ogay, K.1    Suter, M.2    Crameri, R.3    Falchetto, R.4    Fatih, A.5    Monod, M.6
  • 11
    • 0025170681 scopus 로고
    • The fungal vacuole: Composition, function, and biogenesis
    • Klionsky, D.J., Herman, P. K., Emr, S.D.: The fungal vacuole: composition, function, and biogenesis. Microbiol. Rev. 54, 266-292 (1990).
    • (1990) Microbiol. Rev. , vol.54 , pp. 266-292
    • Klionsky, D.J.1    Herman, P.K.2    Emr, S.D.3
  • 12
    • 0000147902 scopus 로고
    • Aspergillosis
    • Lea & Febiger, Philadelphia
    • Kwon-Chung, K. J., Bennett, J.: Aspergillosis. In: Medical Mycology, pp. 201-247. Lea & Febiger, Philadelphia 1992.
    • (1992) Medical Mycology , pp. 201-247
    • Kwon-Chung, K.J.1    Bennett, J.2
  • 13
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli, U.K.: Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685 (1970).
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 14
    • 0032916340 scopus 로고    scopus 로고
    • Aspergillus fumigatus and aspergillosis
    • Latgé, J. P.: Aspergillus fumigatus and aspergillosis. Clin. Microbiol. Rev. 12, 310-350 (1999).
    • (1999) Clin. Microbiol. Rev. , vol.12 , pp. 310-350
    • Latgé, J.P.1
  • 15
    • 0029125381 scopus 로고
    • Molecular cloning of the cDNA and gene for an elastinolytic aspartic proteinase from Aspergillus fumigatus and evidence of its secretion by the fungus during invasion of the host lung
    • Lee, J. D., Kolattukudy, P. E.: Molecular cloning of the cDNA and gene for an elastinolytic aspartic proteinase from Aspergillus fumigatus and evidence of its secretion by the fungus during invasion of the host lung. Infect. Immun. 63, 3796-3803 (1995).
    • (1995) Infect. Immun. , vol.63 , pp. 3796-3803
    • Lee, J.D.1    Kolattukudy, P.E.2
  • 16
    • 0024978006 scopus 로고
    • Nucleotide sequence of the Candida albicans aspartyl proteinase gene
    • Lott, T. J., Page, L. S., Boiron, P., Benson, J., Reiss, E.: Nucleotide sequence of the Candida albicans aspartyl proteinase gene. Nucleic Acids Res. 17, 1779 (1989).
    • (1989) Nucleic Acids Res. , vol.17 , pp. 1779
    • Lott, T.J.1    Page, L.S.2    Boiron, P.3    Benson, J.4    Reiss, E.5
  • 18
    • 0030929482 scopus 로고    scopus 로고
    • Correlation between endoglucanase secretion and cell wall strength in oomycete hyphae: Implications for growth and morphogenesis
    • Money, N. P., Hill, T. W.: Correlation between endoglucanase secretion and cell wall strength in oomycete hyphae: implications for growth and morphogenesis. Mycologia 89, 777-785 (1997).
    • (1997) Mycologia , vol.89 , pp. 777-785
    • Money, N.P.1    Hill, T.W.2
  • 19
    • 0027377215 scopus 로고
    • Isolation and characterization of a secreted metalloprotease of Aspergillus fumigatus
    • Monod, M., Paris, S., Sanglard, D., Jaton-Ogay, K., Bille, J., Latgé, J. P.: Isolation and characterization of a secreted metalloprotease of Aspergillus fumigatus. Infect. Immun. 61, 4099-4104 (1993).
    • (1993) Infect. Immun. , vol.61 , pp. 4099-4104
    • Monod, M.1    Paris, S.2    Sanglard, D.3    Jaton-Ogay, K.4    Bille, J.5    Latgé, J.P.6
  • 20
    • 0025847569 scopus 로고
    • Isolation and characterisation of an extracellular alkaline protease of Aspergillus fumigatus
    • Monod, M., Togni, G., Rahalison, L., Frenk, E.: Isolation and characterisation of an extracellular alkaline protease of Aspergillus fumigatus. J. Med. Microbiol. 35, 23-28 (1991).
    • (1991) J. Med. Microbiol. , vol.35 , pp. 23-28
    • Monod, M.1    Togni, G.2    Rahalison, L.3    Frenk, E.4
  • 21
    • 0030968722 scopus 로고    scopus 로고
    • Metallopeptidase in Candida albicans: Immunolocalization in yeast
    • Moudni, F. B., Rodier, M. H., Babin, P., Jacquemin, J. L.: Metallopeptidase in Candida albicans: immunolocalization in yeast. J. Mycol. Med. 7, 5-9 (1997).
    • (1997) J. Mycol. Med. , vol.7 , pp. 5-9
    • Moudni, F.B.1    Rodier, M.H.2    Babin, P.3    Jacquemin, J.L.4
  • 22
    • 0002145440 scopus 로고
    • Isolation of protease negative mutants of Aspergillus fumigatus by insertion of a disrupted gene
    • B. Maresca and G. S. Kobayashi, eds, Telos Press, New York
    • Paris, S.: Isolation of protease negative mutants of Aspergillus fumigatus by insertion of a disrupted gene. In: Molecular Biology of Pathogenic fungi. A Laboratory Manual (B. Maresca and G. S. Kobayashi, eds), pp. 49-55. Telos Press, New York 1994.
    • (1994) Molecular Biology of Pathogenic Fungi. A Laboratory Manual , pp. 49-55
    • Paris, S.1
  • 23
    • 0023512725 scopus 로고
    • Transformation of aspergillus based on hygromycin B resistance marker from Escherichia coli
    • Punt, S. J., Oliver, P. O., Dingemanse, M. A., Pouwels, P. H., van den Hondel, C. A. M. J. J.: Transformation of Aspergillus based on hygromycin B resistance marker from Escherichia coli. Gene 56, 117-124 (1987).
    • (1987) Gene , vol.56 , pp. 117-124
    • Punt, S.J.1    Oliver, P.O.2    Dingemanse, M.A.3    Pouwels, P.H.4    Van Den Hondel, C.A.M.J.J.5
  • 24
    • 0029004315 scopus 로고
    • Families of aspartic peptidases, and those of unknown catalytic mechanism
    • Rawlings, N. D., Barrett, A. J.: Families of aspartic peptidases, and those of unknown catalytic mechanism. Methods Enzymol. 248, 105-120 (1995).
    • (1995) Methods Enzymol. , vol.248 , pp. 105-120
    • Rawlings, N.D.1    Barrett, A.J.2
  • 25
    • 0025669926 scopus 로고
    • Purification and characterisation of an extracellular serine proteinase from Aspergillus fumigatus and its detection in tissue
    • Reichard, U., Büttner, S., Eiffert, H., Staib, F., Rüchel, R.: Purification and characterisation of an extracellular serine proteinase from Aspergillus fumigatus and its detection in tissue. J. Med. Microbiol. 33, 243-251 (1990).
    • (1990) J. Med. Microbiol. , vol.33 , pp. 243-251
    • Reichard, U.1    Büttner, S.2    Eiffert, H.3    Staib, F.4    Rüchel, R.5
  • 26
    • 84907125058 scopus 로고
    • Purification and characterization of an extracellular aspartic proteinase from Aspergillus fumigatus
    • Reichard, U., Eiffert, H., Rüchel, R.: Purification and characterization of an extracellular aspartic proteinase from Aspergillus fumigatus. J. Med. Vet. Mycol. 32, 427-436 (1994).
    • (1994) J. Med. Vet. Mycol. , vol.32 , pp. 427-436
    • Reichard, U.1    Eiffert, H.2    Rüchel, R.3
  • 27
    • 79961220619 scopus 로고    scopus 로고
    • Virulence of an aspergillopepsin-deficient mutant of Aspergillus fumigatus and evidence for another aspartic proteinase linked to the fungal cell wall
    • Reichard, U., Monod, M., Odds, F., Rüchel, R.: Virulence of an aspergillopepsin-deficient mutant of Aspergillus fumigatus and evidence for another aspartic proteinase linked to the fungal cell wall. J. Med. Vet. Mycol. 35, 189-196 (1997).
    • (1997) J. Med. Vet. Mycol. , vol.35 , pp. 189-196
    • Reichard, U.1    Monod, M.2    Odds, F.3    Rüchel, R.4
  • 28
    • 0029056552 scopus 로고
    • Molecular cloning and sequencing of the gene encoding an extracellular aspartic proteinase from Aspergillus fumigatus
    • Reichard, U., Monod, M., Rüchel, R.: Molecular cloning and sequencing of the gene encoding an extracellular aspartic proteinase from Aspergillus fumigatus. FEMS Microbiol. Lett. 130, 69-74 (1995).
    • (1995) FEMS Microbiol. Lett. , vol.130 , pp. 69-74
    • Reichard, U.1    Monod, M.2    Rüchel, R.3
  • 29
    • 0029975178 scopus 로고    scopus 로고
    • Expression pattern of aspartic proteinase antigens in aspergilli
    • Reichard, U., Monod, M., Rüchel, R.: Expression pattern of aspartic proteinase antigens in aspergilli. Mycoses 39, 99-101 (1996).
    • (1996) Mycoses , vol.39 , pp. 99-101
    • Reichard, U.1    Monod, M.2    Rüchel, R.3
  • 30
    • 0022470653 scopus 로고
    • Overproduction-induced mislocalization of a yeast vacuolar protein allows isolation of its structural gene
    • Rothman, J. H., Hunter, C. P., Valls, L. A., Stevens, T. H.: Overproduction-induced mislocalization of a yeast vacuolar protein allows isolation of its structural gene. Proc. Natl. Acad. Sci. USA 83, 3248-3252 (1986).
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 3248-3252
    • Rothman, J.H.1    Hunter, C.P.2    Valls, L.A.3    Stevens, T.H.4
  • 31
    • 0019503111 scopus 로고
    • Properties of a purified proteinase from the yeast Candida albicans
    • Rüchel, R.: Properties of a purified proteinase from the yeast Candida albicans. Biochim. Biophys. Acta 659, 99-113 (1981).
    • (1981) Biochim. Biophys. Acta , vol.659 , pp. 99-113
    • Rüchel, R.1
  • 34
    • 0016137481 scopus 로고
    • Studies on a protease (elastase) from Pseudomonas aeruginosa, I: Formation and purification of the protease
    • Hoppe Seylers
    • Scharmann, W., Balke, E.: [Studies on a protease (elastase) from Pseudomonas aeruginosa, I: formation and purification of the protease (author's transl)]. Hoppe Seylers Z. Physiol. Chem. 355, 443-450 (1974).
    • (1974) Z. Physiol. Chem. , vol.355 , pp. 443-450
    • Scharmann, W.1    Balke, E.2
  • 35
    • 0027230493 scopus 로고
    • The alkaline protease of Aspergillus fumigatus is not a virulence determinant in two murine models of invasive pulmonary aspergillosis
    • Tang, C. M., Cohen, J., Krausz, T., Van Noorden, S., Holden, D.W.: The alkaline protease of Aspergillus fumigatus is not a virulence determinant in two murine models of invasive pulmonary aspergillosis. Infect. Immun. 61, 1650-1656 (1993).
    • (1993) Infect. Immun. , vol.61 , pp. 1650-1656
    • Tang, C.M.1    Cohen, J.2    Krausz, T.3    Van Noorden, S.4    Holden, D.W.5
  • 37
    • 0030750269 scopus 로고    scopus 로고
    • Disruption of three acid proteases in Aspergillus niger - Effects on protease spectrum, intracellular proteolysis, and degradation of target proteins
    • van den Hombergh, J. P., Sollewijn Gelpke, M. D., van de Vondervoort, P. J., Buxton, F. P., Visser, J.: Disruption of three acid proteases in Aspergillus niger - effects on protease spectrum, intracellular proteolysis, and degradation of target proteins. Eur. J. Biochem. 247, 605-613 (1997).
    • (1997) Eur. J. Biochem. , vol.247 , pp. 605-613
    • Van Den Hombergh, J.P.1    Sollewijn Gelpke, M.D.2    Van De Vondervoort, P.J.3    Buxton, F.P.4    Visser, J.5
  • 38
    • 0029786284 scopus 로고    scopus 로고
    • Characterization of a vacuolar protease in Neurospora crassa and the use of gene RIPing to generate protease-deficient strains
    • Vazquez-Laslop, N., Tenney, K., Bowman, B. J.: Characterization of a vacuolar protease in Neurospora crassa and the use of gene RIPing to generate protease-deficient strains. J. Biol. Chem. 271, 21 944-21 949 (1996).
    • (1996) J. Biol. Chem. , vol.271 , pp. 21944-21949
    • Vazquez-Laslop, N.1    Tenney, K.2    Bowman, B.J.3
  • 39
    • 0023046815 scopus 로고
    • A new method for predicting signal sequence cleavage sites
    • von Heijne, G.: A new method for predicting signal sequence cleavage sites. Nucleic Acids Res. 14, 4683-4690 (1986).
    • (1986) Nucleic Acids Res. , vol.14 , pp. 4683-4690
    • Von Heijne, G.1
  • 40
    • 0000745994 scopus 로고
    • Isolierung und Kristallisation des Gärungsfermentes Enolase
    • Warburg, O., Christian, W.: Isolierung und Kristallisation des Gärungsfermentes Enolase. Biochemische Zeitschrift 310, 384-421 (1942).
    • (1942) Biochemische Zeitschrift , vol.310 , pp. 384-421
    • Warburg, O.1    Christian, W.2
  • 41
    • 0022755757 scopus 로고
    • The PEP4 gene encodes an aspartyl protease implicated in the posttranslational regulation of Saccharomyces cerevisiae vacuolar hydrolases
    • Woolford, C. A., Daniels, L.B., Park, F. J., Jones, E. W., Van Arsdell, J. N., Innis, M. A.: The PEP4 gene encodes an aspartyl protease implicated in the posttranslational regulation of Saccharomyces cerevisiae vacuolar hydrolases. Mol. Cell. Biol. 6, 2500-2510 (1986).
    • (1986) Mol. Cell. Biol. , vol.6 , pp. 2500-2510
    • Woolford, C.A.1    Daniels, L.B.2    Park, F.J.3    Jones, E.W.4    Van Arsdell, J.N.5    Innis, M.A.6
  • 42
    • 0023280597 scopus 로고
    • Isolation and characterization of an extracellular proteinase of Coccidioides immitis
    • Yuan, L., Cole, G. T.: Isolation and characterization of an extracellular proteinase of Coccidioides immitis. Infect. Immun. 55, 1970-1978 (1987).
    • (1987) Infect. Immun. , vol.55 , pp. 1970-1978
    • Yuan, L.1    Cole, G.T.2
  • 43
    • 0019345573 scopus 로고
    • Protein degradation, meiosis and sporulation in proteinase-deficient mutants of Saccharomyces cerevisiae
    • Zubenko, G. S., Jones, E. W.: Protein degradation, meiosis and sporulation in proteinase-deficient mutants of Saccharomyces cerevisiae. Genetics 97, 45-64 (1981).
    • (1981) Genetics , vol.97 , pp. 45-64
    • Zubenko, G.S.1    Jones, E.W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.