-
1
-
-
0023693947
-
Multifactorial resistance to Adriamycin: Relationship of DNA repair, glutathione transferase activity, drug efflux, and P-glycoprotein in cloned cell lines of Adriamycin-sensitive and -resistant P388 leukemia
-
Deffie, A. M., Alam, T., Seneviratne, C., Beenken, S. W., Batra, J. K., Shea, T. C., Henner, W. D., and Goldenberg, G. J. Multifactorial resistance to Adriamycin: relationship of DNA repair, glutathione transferase activity, drug efflux, and P-glycoprotein in cloned cell lines of Adriamycin-sensitive and -resistant P388 leukemia. Cancer Res., 48: 3595-3602, 1988.
-
(1988)
Cancer Res.
, vol.48
, pp. 3595-3602
-
-
Deffie, A.M.1
Alam, T.2
Seneviratne, C.3
Beenken, S.W.4
Batra, J.K.5
Shea, T.C.6
Henner, W.D.7
Goldenberg, G.J.8
-
2
-
-
0025164884
-
Anthracycline resistance in murine leukemic P388 cells: Role of drug efflux and glutathione related enzymes
-
Nair, S., Singh, S. V., Samy, T. S. A., and Krishan, A. Anthracycline resistance in murine leukemic P388 cells: role of drug efflux and glutathione related enzymes. Biochem. Pharmacol., 39: 723-728, 1990.
-
(1990)
Biochem. Pharmacol.
, vol.39
, pp. 723-728
-
-
Nair, S.1
Singh, S.V.2
Samy, T.S.A.3
Krishan, A.4
-
3
-
-
0020549246
-
Circumvention of vincristine and Adriamycin resistance in vitro and in vivo by calcium influx blockers
-
Tsuruo, T., Iida. H., Nojiri, M., Tsukagoshi, S., and Sakurai, Y. Circumvention of vincristine and Adriamycin resistance in vitro and in vivo by calcium influx blockers. Cancer Res., 43: 2905-2910, 1983.
-
(1983)
Cancer Res.
, vol.43
, pp. 2905-2910
-
-
Tsuruo, T.1
Iida, H.2
Nojiri, M.3
Tsukagoshi, S.4
Sakurai, Y.5
-
4
-
-
0021746060
-
Differential effect of the calmodulin inhibitor trifluoperazine on cellular accumulation, retention, and cytotoxicity of anthracyclines in doxorubicin (Adriamycin)-resistant P388 mouse leukemia cells
-
Ganapathi, R., Grabowski, D., Rouse, W., and Riegler, F. Differential effect of the calmodulin inhibitor trifluoperazine on cellular accumulation, retention, and cytotoxicity of anthracyclines in doxorubicin (Adriamycin)-resistant P388 mouse leukemia cells. Cancer Res., 44: 5056-5061, 1984.
-
(1984)
Cancer Res.
, vol.44
, pp. 5056-5061
-
-
Ganapathi, R.1
Grabowski, D.2
Rouse, W.3
Riegler, F.4
-
5
-
-
0021953802
-
Flow cytometric studies on modulation of cellular Adriamycin retention by phenothiazines
-
Krishan, A., Sauerteig, A., and Wellham, L. Flow cytometric studies on modulation of cellular Adriamycin retention by phenothiazines. Cancer Res., 45: 1046-1051, 1985.
-
(1985)
Cancer Res.
, vol.45
, pp. 1046-1051
-
-
Krishan, A.1
Sauerteig, A.2
Wellham, L.3
-
6
-
-
0023237840
-
Verapamil and Adriamycin in the treatment of drug-resistant ovarian cancer patients
-
Ozols, R. F., Cunnion, R. E., Klecker, R. W., Jr., Hamilton, T. C., Ostchega, Y., Parrillo, J. E., and Young, R. C. Verapamil and Adriamycin in the treatment of drug-resistant ovarian cancer patients. J. Clin. Oncol., 5: 641-647, 1987.
-
(1987)
J. Clin. Oncol.
, vol.5
, pp. 641-647
-
-
Ozols, R.F.1
Cunnion, R.E.2
Klecker R.W., Jr.3
Hamilton, T.C.4
Ostchega, Y.5
Parrillo, J.E.6
Young, R.C.7
-
7
-
-
0023948518
-
Clinical modulation of doxorubicin resistance by the calmodulin-inhibitor, trifluoperazine: A phase I/II trial
-
Miller, R. L., Bukowski, R. M., Budd, G. T., Purvis, J., Weick, J. K., Shepard, K., Midha, K. K., and Ganapathi, R. Clinical modulation of doxorubicin resistance by the calmodulin-inhibitor, trifluoperazine: a Phase I/II trial. J. Clin. Oncol., 6: 880-888, 1988.
-
(1988)
J. Clin. Oncol.
, vol.6
, pp. 880-888
-
-
Miller, R.L.1
Bukowski, R.M.2
Budd, G.T.3
Purvis, J.4
Weick, J.K.5
Shepard, K.6
Midha, K.K.7
Ganapathi, R.8
-
8
-
-
0028816350
-
A phase II randomized study of oral verapamil as a chemosensitizer to reverse drug resistance in patients with refractory myeloma: A Southwest Oncology Group study
-
Dalton, W. S., Crowley, J. J., Salmon, S. S., Grogan, T. M., Laufman, L. R., Weiss, G. R., and Bonnet, J. D. A Phase II randomized study of oral verapamil as a chemosensitizer to reverse drug resistance in patients with refractory myeloma: a Southwest Oncology Group study. Cancer (Phila.), 75: 815-820, 1995.
-
(1995)
Cancer (Phila.)
, vol.75
, pp. 815-820
-
-
Dalton, W.S.1
Crowley, J.J.2
Salmon, S.S.3
Grogan, T.M.4
Laufman, L.R.5
Weiss, G.R.6
Bonnet, J.D.7
-
9
-
-
0030738096
-
Modulation and prevention of multidrug resistance by inhibitors of P-glycoprotein
-
Sikic, B. I., Fisher, G. A., Lum, B. L., Halsey, J., Beketic-Oreskovic, L., and Chen, G. Modulation and prevention of multidrug resistance by inhibitors of P-glycoprotein. Cancer Chemother. Pharmacol., 40 (Suppl.): S13-S19, 1997.
-
(1997)
Cancer Chemother. Pharmacol.
, vol.40
, Issue.SUPPL.
-
-
Sikic, B.I.1
Fisher, G.A.2
Lum, B.L.3
Halsey, J.4
Beketic-Oreskovic, L.5
Chen, G.6
-
10
-
-
0023175712
-
Patterns of anthracycline retention modulation in human tumor cells
-
Krishan, A., Sridhar, K. S., Davila, E., Vogel, C., and Stemheim, W. Patterns of anthracycline retention modulation in human tumor cells. Cytometry, 8: 306-314, 1987.
-
(1987)
Cytometry
, vol.8
, pp. 306-314
-
-
Krishan, A.1
Sridhar, K.S.2
Davila, E.3
Vogel, C.4
Stemheim, W.5
-
11
-
-
0027408928
-
Prochlorperazine as a doxorubicin-efflux blocker: Phase I clinical and pharmacokinetics studies
-
Sridhar, K. S., Krishan, A., Samy, T. S. A., Sauerteig, A., Wellham, L. L., McPhee, G., Duncan, R. C., Anac, S. Y., Ardalan, B., and Benedetto, P. W. Prochlorperazine as a doxorubicin-efflux blocker: Phase I clinical and pharmacokinetics studies. Cancer Chemother. Pharmacol., 31: 423-430, 1993.
-
(1993)
Cancer Chemother. Pharmacol.
, vol.31
, pp. 423-430
-
-
Sridhar, K.S.1
Krishan, A.2
Samy, T.S.A.3
Sauerteig, A.4
Wellham, L.L.5
McPhee, G.6
Duncan, R.C.7
Anac, S.Y.8
Ardalan, B.9
Benedetto, P.W.10
-
12
-
-
0027930981
-
Phase I and pharmacokinetic studies of prochlorperazine 2-hour IV infusion as a doxorubicin efflux blocker
-
Sridhar, K. S., Krishan, A., Samy, T. S. A., Duncan, R. C., Sauerteig, A., McPhee, G. V., Auguste, M. E., Benedetto, P. W., and Waldman, S. Phase I and pharmacokinetic studies of prochlorperazine 2-hour IV infusion as a doxorubicin efflux blocker. Cancer Chemother. Pharmacol., 34: 377-324, 1994.
-
(1994)
Cancer Chemother. Pharmacol.
, vol.34
, pp. 377-1324
-
-
Sridhar, K.S.1
Krishan, A.2
Samy, T.S.A.3
Duncan, R.C.4
Sauerteig, A.5
McPhee, G.V.6
Auguste, M.E.7
Benedetto, P.W.8
Waldman, S.9
-
13
-
-
0342869601
-
Study of escalating doses of dipyridarnole (DPL) and fixed dose of doxorubicin (DOX) in refractory cancer patients
-
Sridhar, K. S., Krishan, A., Samy, T. S. A., McPhee, G. V., Sauerteig, A., Ramachandran, C., Benedetto, P. W., and Hussein, A. Study of escalating doses of dipyridarnole (DPL) and fixed dose of doxorubicin (DOX) in refractory cancer patients. Proc. Am. Assoc. Cancer Res., 35: 360, 1994.
-
(1994)
Proc. Am. Assoc. Cancer Res.
, vol.35
, pp. 360
-
-
Sridhar, K.S.1
Krishan, A.2
Samy, T.S.A.3
McPhee, G.V.4
Sauerteig, A.5
Ramachandran, C.6
Benedetto, P.W.7
Hussein, A.8
-
14
-
-
0025328976
-
Combined use of cyclosporin A and verapamil in modulating multidrug resistance in human leukemia cell lines
-
Hu, X. F., Martin, T. J., Bell, D. R., de Luise, M., and Zalcberg, J. R. Combined use of cyclosporin A and verapamil in modulating multidrug resistance in human leukemia cell lines. Cancer Res., 50: 2953-2957, 1990.
-
(1990)
Cancer Res.
, vol.50
, pp. 2953-2957
-
-
Hu, X.F.1
Martin, T.J.2
Bell, D.R.3
De Luise, M.A.4
Zalcberg, J.R.5
-
15
-
-
0025978845
-
Synergistic inhibition by verapamil and quinine of P-glycoprotein-mediated multidrug resistance in a human myeloma cell line model
-
Lehnert, M., Dalton, W. S., Roe, D., Emerson, S., and Salmon, S. E. Synergistic inhibition by verapamil and quinine of P-glycoprotein-mediated multidrug resistance in a human myeloma cell line model. Blood, 77: 348-354, 1991.
-
(1991)
Blood
, vol.77
, pp. 348-354
-
-
Lehnert, M.1
Dalton, W.S.2
Roe, D.3
Emerson, S.4
Salmon, S.E.5
-
16
-
-
0029590142
-
Saturation reversal of the multidrug pump using many reversers in low-dose combinations
-
Lyubimov, E., Lan, L. B., Pashinsky, I., Ayesh, S., and Stein, W. D. Saturation reversal of the multidrug pump using many reversers in low-dose combinations. Anti-Cancer Drugs, 6: 2-35, 1995.
-
(1995)
Anti-cancer Drugs
, vol.6
, pp. 2-35
-
-
Lyubimov, E.1
Lan, L.B.2
Pashinsky, I.3
Ayesh, S.4
Stein, W.D.5
-
17
-
-
0030004763
-
Co-operative, competitive and non-competitive interactions between modulators of P-glycoprotein
-
Ayesh, S., Shao, S., and Stein, W. D. Co-operative, competitive and non-competitive interactions between modulators of P-glycoprotein. Biochim. Biophys. Acta, 1316: 8-18, 1996.
-
(1996)
Biochim. Biophys. Acta
, vol.1316
, pp. 8-18
-
-
Ayesh, S.1
Shao, S.2
Stein, W.D.3
-
18
-
-
0023899909
-
Anthracycline-induced DNA breaks and resealing in doxorubicin-resistant murine leukemic P388 cells
-
Maniar, N., Samy, T. S. A., Krishan, A., and Israel, M. Anthracycline-induced DNA breaks and resealing in doxorubicin-resistant murine leukemic P388 cells. Biochem. Pharmacol., 37: 1763-1772, 1988.
-
(1988)
Biochem. Pharmacol.
, vol.37
, pp. 1763-1772
-
-
Maniar, N.1
Samy, T.S.A.2
Krishan, A.3
Israel, M.4
-
19
-
-
0017102107
-
Classification of human colorectal adenocarcinoma cell lines
-
Leibovitz, A. L., Stinson, J. C., McCombs, W. B., McCoy, C. E., Mazur, K. C., and Mabry, N. D. Classification of human colorectal adenocarcinoma cell lines. Cancer Res., 36: 4562-4569, 1976.
-
(1976)
Cancer Res.
, vol.36
, pp. 4562-4569
-
-
Leibovitz, A.L.1
Stinson, J.C.2
McCombs, W.B.3
McCoy, C.E.4
Mazur, K.C.5
Mabry, N.D.6
-
20
-
-
0030737595
-
Flow cytometric analysis of the multiple drug resistance phenotype
-
Krishan, A., Sauerteig, A., Andritsch, I., and Wellham, L. Flow cytometric analysis of the multiple drug resistance phenotype. Leukemia(Baltimore), 11: 1138-1146, 1997.
-
(1997)
Leukemia(Baltimore)
, vol.11
, pp. 1138-1146
-
-
Krishan, A.1
Sauerteig, A.2
Andritsch, I.3
Wellham, L.4
-
21
-
-
0031451801
-
Simultaneous quantitation of plasma doxorubicin and prochlorperazine content by high performance chromatography
-
Mou, C., Ganju, N., Sridhar, K., and Krishan, A. Simultaneous quantitation of plasma doxorubicin and prochlorperazine content by high performance chromatography. J. Chromatogr. B, 703: 217-224, 1997.
-
(1997)
J. Chromatogr. B
, vol.703
, pp. 217-224
-
-
Mou, C.1
Ganju, N.2
Sridhar, K.3
Krishan, A.4
-
22
-
-
0343740122
-
-
Stockholm: Swedish Pharmaceutical Press
-
Gabrielsson, J., and Weiner, D. Pharmacokinetic and Pharmacodynamic Data Analysis Concepts and Applications, Vol. 1, pp. 107-114. Stockholm: Swedish Pharmaceutical Press, 1994.
-
(1994)
Pharmacokinetic and Pharmacodynamic Data Analysis Concepts and Applications
, vol.1
, pp. 107-114
-
-
Gabrielsson, J.1
Weiner, D.2
-
23
-
-
0023685838
-
Phase I clinical trial of a combination of dipyridarnole and acivicin based upon inhibition of nucleoside salvage
-
Willson, J. K. V., Fischer, P. H., Tutsch, K., Alberti, D., Simon, K., Hamilton, R. D., Bruggink, J., Koeller, J. M., Tormey, D. C., Earhart, R. H., Ranhosky, A., and Trump, D. L. Phase I clinical trial of a combination of dipyridarnole and acivicin based upon inhibition of nucleoside salvage. Cancer Res., 48: 5585-5590, 1988.
-
(1988)
Cancer Res.
, vol.48
, pp. 5585-5590
-
-
Willson, J.K.V.1
Fischer, P.H.2
Tutsch, K.3
Alberti, D.4
Simon, K.5
Hamilton, R.D.6
Bruggink, J.7
Koeller, J.M.8
Tormey, D.C.9
Earhart, R.H.10
Ranhosky, A.11
Trump, D.L.12
-
24
-
-
0021118703
-
Quantitative analysis of dose-effect relationships: The combined effects of multiple drugs or enzyme inhibitors
-
Chou, T. C., and Talalay, P. Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors. Adv. Enzyme Regul., 22: 27-55, 1984.
-
(1984)
Adv. Enzyme Regul.
, vol.22
, pp. 27-55
-
-
Chou, T.C.1
Talalay, P.2
-
25
-
-
0016232808
-
Cytofluorescence localization of Adriamycin and daunorubicin
-
Egorin, M. J., Hildebrand, R. C., Cimino, E. F., and Bachur, N. R. Cytofluorescence localization of Adriamycin and daunorubicin. Cancer Res., 34: 2243-2245, 1974.
-
(1974)
Cancer Res.
, vol.34
, pp. 2243-2245
-
-
Egorin, M.J.1
Hildebrand, R.C.2
Cimino, E.F.3
Bachur, N.R.4
-
26
-
-
0030976879
-
P-glycoprotein substrates and antagonists cluster into two distinct groups
-
Scala, S., Akhmed, N., Rao, U. S., Paull, K., Lan, L. B., Dickstein, B., Lee, J. S., Elgemeie, G. H., Stein, W. D., and Bates, S. E. P-glycoprotein substrates and antagonists cluster into two distinct groups. Mol. Pharmacol., 51: 1024-1033, 1997.
-
(1997)
Mol. Pharmacol.
, vol.51
, pp. 1024-1033
-
-
Scala, S.1
Akhmed, N.2
Rao, U.S.3
Paull, K.4
Lan, L.B.5
Dickstein, B.6
Lee, J.S.7
Elgemeie, G.H.8
Stein, W.D.9
Bates, S.E.10
-
27
-
-
0030966409
-
Kinetics of the multidrug transporter (P-glycoprotein) and its reversal
-
Stein, W. D. Kinetics of the multidrug transporter (P-glycoprotein) and its reversal. Physiol. Rev., 77: 545-590, 1997.
-
(1997)
Physiol. Rev.
, vol.77
, pp. 545-590
-
-
Stein, W.D.1
|