In vivo intermolecular double-quantum imaging on a clinical 1.5 T MR scanner

Magnetic Resonance in Medicine

Volumn 43, Issue 3, 2000, Pages 335-341

  Zhong, Jianhui ^a   Chen, Zhong ^a   Kwok, Edmund ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

Double quantum coherence; Intermolecular dipole dipole interaction; MRI; Sensitivity

Indexed keywords

BRAIN; MAGNETIC RESONANCE IMAGING; SCANNING;

DIPOLE DIPOLE INTERACTIONS; DOUBLE QUANTUM COHERENCES; FIELD STRENGTHS; IMAGING SEQUENCE; INTERMOLECULAR DOUBLE-QUANTUM COHERENCES; MULTIPLE-QUANTUM COHERENCES; SENSITIVITY; SENSITIVITY INCREASE;

QUANTUM THEORY;

ARTICLE; BRAIN; HUMAN; HUMAN TISSUE; IMAGE ANALYSIS; IMAGING SYSTEM; MOLECULAR INTERACTION; NUCLEAR MAGNETIC RESONANCE IMAGING; SIGNAL DETECTION; SOFT TISSUE;

EID: 0034050969     PISSN: 07403194     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1522-2594(200003)43:3<335::AID-MRM3>3.0.CO;2-1     Document Type: Article

References (25)

1. Deville G, Bernier M, Delrieux JM. NMR multiple echoes observed in solid 3He. Phys Rev B 1979;19:5666-5687.
2. Bowtell R, Bowley RM, Glover P. Multiple spin echoes in liquids in a high magnetic field. J Magn Reson 1990;88:643-651.
3. Jeener J, Vassenbroek A, Broekaert P. Unified derivation of the dipolar field and relaxation terms in the Bloch-Redfield equations of liquid NMR. J Chem Phys 1995;103:1309-1332.
4. Vlassenbroek A, Jeener J, Broekaert P. Macroscopic and microscopic fields in high-resolution liquid NMR. J Magn Reson A 1996;118:234-246.
5. Braekaert P, Vlassenbroek A, Jeener J, Lippens G, Wieruszeski JM. Observation and selective suppression of the dipolar-field effects in 2D NMR in liquid in homogeneous fields. J Magn Reson A 1996;120:97-104.
6. Levitt MH. Demagnetization field effects in two-dimensional solution NMR. Concepts Magn Reson 1996;8:77-103.
7. Warren WS, Richter W, Andreotti AH, Farmer BT II. Generation of impossible cross-peaks between bulk water and biomolecules in solution NMR. Science 1993;262:2005-2009.
8. Lee S, Richter W, Vathyam S, Warren WS. Quantum treatment of the effects of dipolar-dipolar interactions in liquid nuclear magnetic resonance. J Chem Phys 1996;105:874-900.
9. Vathyam S, Lee S, Warren WS. Homogeneous NMR spectra in inhomogeneous field. Science 1996;272:92-96.
10. Warren WS, Ahn S. The boundary between liquidlike and solidlike behavior in magnetic resonance. J Chem Phys 1998;108:1313-1325.
11. Enss T, Ahn S, Warren WS. Visualizing the dipolar field in solution NMR and MRI imaging: three-dimensional structure simulations. Chem Phys Lett 1999;305:101-108.
12. Himmich R, Ardelean I. Intermolecular multiple-quantum coherence transfer echoes and multiple echoes in nuclear magnetic resonance. J Chem Phys 1999;110:3708-3713.
13. Richter W, Lee S, Warren WS, He QH. Imaging with intermolecular multiple-quantum coherences in solution nuclear magnetic resonance. Science 1995;267:654-657.
14. Warren WS, Ahn SD, Mescher M, Garwood M, Ugurbil K, Richter W, Rizi RR, Hopkins J, Leigh JS. MR imaging contrast enhancement based on intermolecular zero quantum coherences. Science 1998;281:247-251.
15. Rizi RR, Ahn S, Alsop DC, Hopkins J, Gerett-Roe S, Schnall MD, Leigh JS, Warren WS. Human brain imaging with intermolecular zero quantum coherences in 4T. In: Abstract Book 7th Annu Meet Soc Magn Reson, Philadelphia, 1999. p 654.
16. Tsoref L, Shinar H, Seo Y, Eliav U, Navon G. Proton double-quantum filtered MRI - a new method for imaging ordered tissues. Magn Reson Med 1998;40:720-726.
17. Mori S, Hurd RE, van Zijl PCM. Imaging of shifted stimulated echoes and multiple spin echoes. Magn Reson Med 1997;37:336-340.
18. Bifone A, Payne GS, Leach MO. In vivo multiple spin echoes. J Magn Reson 1998;135:33-36.
19. Haacke EM, Brown RW, Thompson MR, Venkatesan R. Magnetic resonance imaging - physical principles and sequence design. New York: Wiley-Liss; 1999.
20. Elliot M, Insko EK, Greenman RL, Leigh JS. Improved resolution and signal-to-noise ratio in MRI via enhanced signal digitization. J Magn Reson 1998;130:300-304.
21. Redfield AG, Kunz SD. Analog filtering of large solvent signals for improved dynamic range in high-resolution NMR. J Magn Reson 1998; 130:111-118.
22. van Zijl PCM, Johnson MO, Mori S, Hurd RE. Magic-angle-gradient double-quantum-filtered COSY. J Magn Reson A 1995;113:265-270.
23. Mattiello DL, Warren WS, Mueller L, Farmer BT. Minimizing the water resonance in biological NMR: characterization and suppression of intermolecular diplolar interactions by multiple-axis gradients. J Am Chem Soc 1996;118:3253-3261.
24. Thomas DJ, Mitschang L, Simon Bernd, Oschkinat H. Signal selection in high-resolution NMR by pulse field gradients. II. The design of gradient pulse sequences. J Magn Reson 1999;137:10-24.
25. Kim SG, Tsekos NV. Perfusion imaging by a flow-sensitive alternating inversion recovery (FAIR) technique: application to functional brain imaging. Magn Reson Med 1997;37:425-435.