-
3
-
-
77049308856
-
Aging: A theory based on free radical and radiation chemistry
-
Harman D. Aging: a theory based on free radical and radiation chemistry. J Gerontol 1956;11:298-300.
-
(1956)
J Gerontol
, vol.11
, pp. 298-300
-
-
Harman, D.1
-
5
-
-
0001557130
-
Lipid peroxidation: Mechanisms, analysis, enzymology and biological relevance
-
Sies H, ed. London: Academic Press
-
Kappus H. Lipid peroxidation: mechanisms, analysis, enzymology and biological relevance. In: Sies H, ed. Oxidative Stress. London: Academic Press, 1985: 273-310.
-
(1985)
Oxidative Stress
, pp. 273-310
-
-
Kappus, H.1
-
7
-
-
0014423307
-
Evolution of senescence and specific longevity
-
Edney EB, Gill RW. Evolution of senescence and specific longevity. Nature 1967;220:281-282.
-
(1967)
Nature
, vol.220
, pp. 281-282
-
-
Edney, E.B.1
Gill, R.W.2
-
9
-
-
0027384878
-
Retarded senescence in an insular population of Virginia opossums
-
Austad SN. Retarded senescence in an insular population of Virginia opossums. J Zool 1993;229:695-708.
-
(1993)
J Zool
, vol.229
, pp. 695-708
-
-
Austad, S.N.1
-
10
-
-
0842331263
-
Superoxide dismutase: Correlation with life-span and specific metabolic rate in primate species
-
Tolmasoff JM, Ono T, Cutler RG. Superoxide dismutase: Correlation with life-span and specific metabolic rate in primate species. Proc Natl Acad Sci USA 1980;77:2777-2781.
-
(1980)
Proc Natl Acad Sci USA
, vol.77
, pp. 2777-2781
-
-
Tolmasoff, J.M.1
Ono, T.2
Cutler, R.G.3
-
11
-
-
0021777459
-
Antioxidants and longevity of mammalian species
-
Cutler RG. Antioxidants and longevity of mammalian species. Basic Life Sci 1985;35:15-74.
-
(1985)
Basic Life Sci
, vol.35
, pp. 15-74
-
-
Cutler, R.G.1
-
12
-
-
0002389290
-
Aging and oxygen radicals
-
Taylor AE, Matalon A, Ward P, eds. Bethesda, MD: American Physiological Society
-
Cutler RG. Aging and oxygen radicals. In: Taylor AE, Matalon A, Ward P, eds. Physiology of Oxygen Radicals. Bethesda, MD: American Physiological Society, 1986:251-285.
-
(1986)
Physiology of Oxygen Radicals
, pp. 251-285
-
-
Cutler, R.G.1
-
13
-
-
0026008160
-
Antioxidants and aging
-
Cutler RG. Antioxidants and aging. Am J Clin Nutr 1991;53:3735-3795.
-
(1991)
Am J Clin Nutr
, vol.53
, pp. 3735-3795
-
-
Cutler, R.G.1
-
15
-
-
0028001145
-
A decrease of free radical production near critical targets as a cause of maximum longevity in animals
-
Barja G, Cadenas S, Rojas C, Lopez-Torres M, Perez-Campo R. A decrease of free radical production near critical targets as a cause of maximum longevity in animals. Comp Biochem Physiol Biochem Mol Biol 1994; 108:501-512.
-
(1994)
Comp Biochem Physiol Biochem Mol Biol
, vol.108
, pp. 501-512
-
-
Barja, G.1
Cadenas, S.2
Rojas, C.3
Lopez-Torres, M.4
Perez-Campo, R.5
-
16
-
-
0027196839
-
A comparative study of free radicals in vertebrates - I. Antioxidant enzymes
-
Perez-Campo R, Lopez-Torres M, Rojas C, Cadenas S, Barja G. A comparative study of free radicals in vertebrates - I. Antioxidant enzymes. Comp Biochem Physiol B 1993;105:749-755.
-
(1993)
Comp Biochem Physiol B
, vol.105
, pp. 749-755
-
-
Perez-Campo, R.1
Lopez-Torres, M.2
Rojas, C.3
Cadenas, S.4
Barja, G.5
-
17
-
-
0027949503
-
Longevity and antioxidant enzymes, non-enzyme antioxidants and oxidative stress in the vertebrate lung: A comparative study
-
Perez-Campo R, Lopez-Torres M, Rojas C, Cadenas S, Barja G. Longevity and antioxidant enzymes, non-enzyme antioxidants and oxidative stress in the vertebrate lung: a comparative study. J Comp Physiol B 1994;163:682-689.
-
(1994)
J Comp Physiol B
, vol.163
, pp. 682-689
-
-
Perez-Campo, R.1
Lopez-Torres, M.2
Rojas, C.3
Cadenas, S.4
Barja, G.5
-
18
-
-
0027517591
-
Comparison of mitochondrial prooxidant generation and anti-oxidant defenses between rat and pigeon: Possible basis of variation in longevity and metabolic potential
-
Ku HH, Sohal RS. Comparison of mitochondrial prooxidant generation and anti-oxidant defenses between rat and pigeon: possible basis of variation in longevity and metabolic potential. Mech Ageing Dev 1993;72:67-76.
-
(1993)
Mech Ageing Dev
, vol.72
, pp. 67-76
-
-
Ku, H.H.1
Sohal, R.S.2
-
19
-
-
0021218456
-
Extracellular superoxide dismutase and other superoxide dismutase isoenzymes in tissues from nine mammalian species
-
Marklund SL. Extracellular superoxide dismutase and other superoxide dismutase isoenzymes in tissues from nine mammalian species. Biochem J 1984; 222:649-655.
-
(1984)
Biochem J
, vol.222
, pp. 649-655
-
-
Marklund, S.L.1
-
20
-
-
15844393658
-
Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury
-
Reaume AG, Elliott JL, Hoffman EK, Kowall NW, Ferrante RJ, Siwek DF, Wilcox HM, Flood DG, Beal MF, Brown RH Jr, Scott RW, Snider WD. Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury. Nat Genet 1996;13:43-47.
-
(1996)
Nat Genet
, vol.13
, pp. 43-47
-
-
Reaume, A.G.1
Elliott, J.L.2
Hoffman, E.K.3
Kowall, N.W.4
Ferrante, R.J.5
Siwek, D.F.6
Wilcox, H.M.7
Flood, D.G.8
Beal, M.F.9
Brown Jr., R.H.10
Scott, R.W.11
Snider, W.D.12
-
22
-
-
0028827252
-
Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase
-
Li Y, Huang TT, Carlson EJ, Melov S, Ursell PC, Olson JL, Noble LJ, Yoshimura MP, Berger C, Chan PH, Wallace DC, Epstein CJ. Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase. Nat Genet 1995; 11:376-381.
-
(1995)
Nat Genet
, vol.11
, pp. 376-381
-
-
Li, Y.1
Huang, T.T.2
Carlson, E.J.3
Melov, S.4
Ursell, P.C.5
Olson, J.L.6
Noble, L.J.7
Yoshimura, M.P.8
Berger, C.9
Chan, P.H.10
Wallace, D.C.11
Epstein, C.J.12
-
23
-
-
0026012740
-
Mammalian aging, metabolism, and ecology: Evidence from the bats and marsupials
-
Austad SN, Fischer KE. Mammalian aging, metabolism, and ecology: evidence from the bats and marsupials. J Gerontol 1991;46:B47-B53.
-
(1991)
J Gerontol
, vol.46
-
-
Austad, S.N.1
Fischer, K.E.2
-
24
-
-
0029162729
-
Birds as animal models for the comparative biology of aging: A prospectus
-
Holmes JG, Austad SN. Birds as animal models for the comparative biology of aging: a prospectus. J Gerontol 1995;50A:B59-B66.
-
(1995)
J Gerontol
, vol.50 A
-
-
Holmes, J.G.1
Austad, S.N.2
-
25
-
-
0008902713
-
Life spans: Animals
-
Altman PL, Dittmer DS, eds. Bethesda: Federation of the American Societies for Experimental Biology
-
Altman PL, Dittmer DS. Life spans: animals. In: Altman PL, Dittmer DS, eds. Biology Data Book, ed 2. Bethesda: Federation of the American Societies for Experimental Biology, 1972:1804-1814.
-
(1972)
Biology Data Book, Ed 2
, pp. 1804-1814
-
-
Altman, P.L.1
Dittmer, D.S.2
-
26
-
-
0026073726
-
Mechanisms of protection against damage mediated by the Maillard reaction in aging
-
Monnier VM, Sell DR, Nagaraj RH, Miyata S. Mechanisms of protection against damage mediated by the Maillard reaction in aging. Gerontology 1991;37: 152-165.
-
(1991)
Gerontology
, vol.37
, pp. 152-165
-
-
Monnier, V.M.1
Sell, D.R.2
Nagaraj, R.H.3
Miyata, S.4
-
27
-
-
0029152174
-
Glycation accelerates the oxidation of low density lipoprotein by copper ions
-
Kobayashi K, Watanabe J, Umeda F, Nawata H. Glycation accelerates the oxidation of low density lipoprotein by copper ions. Endocr J 1995;42:461-465.
-
(1995)
Endocr J
, vol.42
, pp. 461-465
-
-
Kobayashi, K.1
Watanabe, J.2
Umeda, F.3
Nawata, H.4
-
28
-
-
0030019678
-
Low fatty acid unsaturation protects against lipid peroxidation in liver mitochondria from long-lived species: The pigeon and human case
-
Pamplona R, Prat J, Cadenas S, Rojas C, Perez-Campo R, Lopez Torres M, Barja G. Low fatty acid unsaturation protects against lipid peroxidation in liver mitochondria from long-lived species: the pigeon and human case. Mech Ageing Dev 1996;86:53-66.
-
(1996)
Mech Ageing Dev
, vol.86
, pp. 53-66
-
-
Pamplona, R.1
Prat, J.2
Cadenas, S.3
Rojas, C.4
Perez-Campo, R.5
Lopez Torres, M.6
Barja, G.7
-
29
-
-
0031686714
-
Mitochondrial membrane peroxidizability index is inversely related to maximum life span in mammals
-
Pamplona R, Portero-Otin M, Riba D, Ruiz C, Prat J, Bellmunt MJ, Barja G. Mitochondrial membrane peroxidizability index is inversely related to maximum life span in mammals. J Lipid Res 1998;39:1989-1994.
-
(1998)
J Lipid Res
, vol.39
, pp. 1989-1994
-
-
Pamplona, R.1
Portero-Otin, M.2
Riba, D.3
Ruiz, C.4
Prat, J.5
Bellmunt, M.J.6
Barja, G.7
-
31
-
-
0028220114
-
Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster
-
Orr WC, Sohal RS. Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster. Science 1994;263:1128-1130.
-
(1994)
Science
, vol.263
, pp. 1128-1130
-
-
Orr, W.C.1
Sohal, R.S.2
-
32
-
-
0031864164
-
Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons
-
Parkes TL, Elia AJ, Dickinson D, Hilliker AJ, Phillips JP, Boulianne GL. Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons. Nature Genet 1998;19:171-174.
-
(1998)
Nature Genet
, vol.19
, pp. 171-174
-
-
Parkes, T.L.1
Elia, A.J.2
Dickinson, D.3
Hilliker, A.J.4
Phillips, J.P.5
Boulianne, G.L.6
-
33
-
-
0032908347
-
FLP recombinase-mediated induction of Cu/Zn-superoxide dismutase transgene expression can extend the life span of adult Drosophila melanogaster flies
-
Sun J, Tower J. FLP recombinase-mediated induction of Cu/Zn-superoxide dismutase transgene expression can extend the life span of adult Drosophila melanogaster flies. Mol Cell Biol 1999;19:216-228.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 216-228
-
-
Sun, J.1
Tower, J.2
-
34
-
-
0032582489
-
Extended life-span and stress resistance in the Drosophila mutant methuselah
-
Lin YJ, Seroude L, Benzer S. Extended life-span and stress resistance in the Drosophila mutant methuselah. Science 1998;282:943-946.
-
(1998)
Science
, vol.282
, pp. 943-946
-
-
Lin, Y.J.1
Seroude, L.2
Benzer, S.3
-
35
-
-
0027515616
-
Aging and resistance to oxidative damage in Caenorhabditis elegans
-
Larsen PL. Aging and resistance to oxidative damage in Caenorhabditis elegans. Proc Natl Acad Sci USA 1993;90:8905-8909.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 8905-8909
-
-
Larsen, P.L.1
-
36
-
-
0027197284
-
Oxidative stress and ageing in Caenorhabditis elegans
-
Vanfleteren JR. Oxidative stress and ageing in Caenorhabditis elegans. Biochem J 1993;292:605-608.
-
(1993)
Biochem J
, vol.292
, pp. 605-608
-
-
Vanfleteren, J.R.1
-
37
-
-
0030793931
-
Sites and mechanisms responsible for the low rate of free radical production of heart mitochondria in the long-lived pigeon
-
Herrero A, Barja G. Sites and mechanisms responsible for the low rate of free radical production of heart mitochondria in the long-lived pigeon. Mech Ageing Dev 1997;98:95-111.
-
(1997)
Mech Ageing Dev
, vol.98
, pp. 95-111
-
-
Herrero, A.1
Barja, G.2
-
38
-
-
0021996572
-
Ubisemiquinone is the electron donor for superoxide formation by complex III of heart mitochondria
-
Turrens JF, Alexandre A, Lehninger AL. Ubisemiquinone is the electron donor for superoxide formation by complex III of heart mitochondria. Arch Biochem Biophys 1985;237:408-414.
-
(1985)
Arch Biochem Biophys
, vol.237
, pp. 408-414
-
-
Turrens, J.F.1
Alexandre, A.2
Lehninger, A.L.3
-
39
-
-
0016690480
-
Protonmotive redox mechanism of the cytochrome b-cl complex in the respiratory chain: Protonmotive ubiquinone cycle
-
Mitchell P. Protonmotive redox mechanism of the cytochrome b-cl complex in the respiratory chain: protonmotive ubiquinone cycle. FEBS Lett 1975;56:1-6.
-
(1975)
FEBS Lett
, vol.56
, pp. 1-6
-
-
Mitchell, P.1
-
40
-
-
0028214381
-
Ubisemiquinones as obligatory intermediates in the electron transfer from NADH to ubiquinone
-
De Jong AM, Albracht SP. Ubisemiquinones as obligatory intermediates in the electron transfer from NADH to ubiquinone. Eur J Biochem 1994;222: 975-982.
-
(1994)
Eur J Biochem
, vol.222
, pp. 975-982
-
-
De Jong, A.M.1
Albracht, S.P.2
-
41
-
-
0030969868
-
Superoxide production by the mitochondrial respiratory chain
-
Turrens JF. Superoxide production by the mitochondrial respiratory chain. Biosci Rep 1997;17:3-8.
-
(1997)
Biosci Rep
, vol.17
, pp. 3-8
-
-
Turrens, J.F.1
-
42
-
-
0015694842
-
Mitochondrial superoxide dismutase. Site of synthesis and intramitochondrial localization
-
Weisiger RA, Fridovich I. Mitochondrial superoxide dismutase. Site of synthesis and intramitochondrial localization. J Biol Chem 1973;248:4793-4796.
-
(1973)
J Biol Chem
, vol.248
, pp. 4793-4796
-
-
Weisiger, R.A.1
Fridovich, I.2
-
43
-
-
0019907606
-
Rat liver Cu,Zn-superoxide dismutase. Subcellular location in lysosomes
-
Geller BL, Winge DR. Rat liver Cu,Zn-superoxide dismutase. Subcellular location in lysosomes. J Biol Chem 1982;257:8945-8952.
-
(1982)
J Biol Chem
, vol.257
, pp. 8945-8952
-
-
Geller, B.L.1
Winge, D.R.2
-
44
-
-
0027448243
-
Distribution of CuZn superoxide dismutase in rat liver
-
Liou W, Chang LY, Geuze HJ, Strous GJ, Crapo JD, Slot JW. Distribution of CuZn superoxide dismutase in rat liver. Free Radic Biol Med 1993;14:201-207.
-
(1993)
Free Radic Biol Med
, vol.14
, pp. 201-207
-
-
Liou, W.1
Chang, L.Y.2
Geuze, H.J.3
Strous, G.J.4
Crapo, J.D.5
Slot, J.W.6
-
45
-
-
0033525897
-
Cloned prokaryotic iron superoxide dismutase protects yeast cells against oxidative stress depending on mitochondrial location
-
Balzan R, Agius DR, Bannister WH. Cloned prokaryotic iron superoxide dismutase protects yeast cells against oxidative stress depending on mitochondrial location. Biochem Biophys Res Commun 1999;256:63-67.
-
(1999)
Biochem Biophys Res Commun
, vol.256
, pp. 63-67
-
-
Balzan, R.1
Agius, D.R.2
Bannister, W.H.3
-
46
-
-
0030983191
-
In situ detection of spontaneous superoxide anion and singlet oxygen production by mitochondria in rat liver and small intestine
-
Kerver ED, Vogels IM, Bosch KS, Vreeling-Sindelarova H, van den Munckhof RJ, Frederiks WM. In situ detection of spontaneous superoxide anion and singlet oxygen production by mitochondria in rat liver and small intestine. Histochem J 1997;29:229-237.
-
(1997)
Histochem J
, vol.29
, pp. 229-237
-
-
Kerver, E.D.1
Vogels, I.M.2
Bosch, K.S.3
Vreeling-Sindelarova, H.4
Van Den Munckhof, R.J.5
Frederiks, W.M.6
-
47
-
-
0018776894
-
Hydroperoxide metabolism in mammalian organs
-
Chance B, Sies H, Boveris A. Hydroperoxide metabolism in mammalian organs. Physiol Rev 1979;59: 527-605.
-
(1979)
Physiol Rev
, vol.59
, pp. 527-605
-
-
Chance, B.1
Sies, H.2
Boveris, A.3
-
48
-
-
0026112682
-
Isolation from wheat mitochondria of a membrane-associated high molecular weight complex involved in DNA synthesis
-
Echeverria M, Robert D, Carde JP, Litvak S. Isolation from wheat mitochondria of a membrane-associated high molecular weight complex involved in DNA synthesis. Plant Mol Biol 1991;16:301-315.
-
(1991)
Plant Mol Biol
, vol.16
, pp. 301-315
-
-
Echeverria, M.1
Robert, D.2
Carde, J.P.3
Litvak, S.4
-
49
-
-
0027017232
-
Mitochondrial DNA deletions in human brain: Regional variability and increase with advanced age
-
Corral-Debrinski M, Horton T, Lott MT, Shoffner JM, Beal MF, Wallace DC. Mitochondrial DNA deletions in human brain: regional variability and increase with advanced age. Nature Genet 1992;2:324-329.
-
(1992)
Nature Genet
, vol.2
, pp. 324-329
-
-
Corral-Debrinski, M.1
Horton, T.2
Lott, M.T.3
Shoffner, J.M.4
Beal, M.F.5
Wallace, D.C.6
-
50
-
-
0026732706
-
A pattern of accumulation of a somatic deletion of mitochondrial DNA in aging human tissues
-
Cortopassi GA, Shibata D, Soong NW, Arnheim N. A pattern of accumulation of a somatic deletion of mitochondrial DNA in aging human tissues. Proc Natl Acad Sci USA 1992;89:7370-7374.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 7370-7374
-
-
Cortopassi, G.A.1
Shibata, D.2
Soong, N.W.3
Arnheim, N.4
-
51
-
-
0027759243
-
Human aging is associated with various point mutations in tRNA genes of mitochondrial DNA
-
Münscher C, Müller-Höcker J, Kadenbach B. Human aging is associated with various point mutations in tRNA genes of mitochondrial DNA. Biol Chem Hoppe Seyler 1993;374:1099-1104.
-
(1993)
Biol Chem Hoppe Seyler
, vol.374
, pp. 1099-1104
-
-
Münscher, C.1
Müller-Höcker, J.2
Kadenbach, B.3
-
52
-
-
2542509453
-
Defects of the respiratory chain in various tissues of old monkeys: A cytochemical-immunocytochemical study
-
Müller-Höcker J, Schäfer S, Link TA, Possekel S, Hammer C. Defects of the respiratory chain in various tissues of old monkeys: a cytochemical-immunocytochemical study. Mech Ageing Dev 1996;86:197-213.
-
(1996)
Mech Ageing Dev
, vol.86
, pp. 197-213
-
-
Müller-Höcker, J.1
Schäfer, S.2
Link, T.A.3
Possekel, S.4
Hammer, C.5
-
53
-
-
0026712284
-
Mitochondrial DNA copy number and mitochondrial DNA deletion in adult and senescent rats
-
Gadaleta MN, Rainaldi G, Lezza AMS, Milella F, Fracasso F, Cantatore P. Mitochondrial DNA copy number and mitochondrial DNA deletion in adult and senescent rats. Mutat Res 1992;275:181-193.
-
(1992)
Mutat Res
, vol.275
, pp. 181-193
-
-
Gadaleta, M.N.1
Rainaldi, G.2
Lezza, A.M.S.3
Milella, F.4
Fracasso, F.5
Cantatore, P.6
-
54
-
-
0027971105
-
Detection and quantitation by competitive PCR of an age-associated increase in a 4.8-kb deletion in rat mitochondrial DNA
-
Edris W, Burgett B, Stine OC, Filburn CR. Detection and quantitation by competitive PCR of an age-associated increase in a 4.8-kb deletion in rat mitochondrial DNA. Mutat Res 1994;316:69-78.
-
(1994)
Mutat Res
, vol.316
, pp. 69-78
-
-
Edris, W.1
Burgett, B.2
Stine, O.C.3
Filburn, C.R.4
-
55
-
-
0027244097
-
Mitochondrial DNA remains intact during Drosophila aging, but the levels of mitochondrial transcripts are significantly reduced
-
Calleja M, Pena P, Ugalde C, Ferreiro C, Marco R, Garesse R. Mitochondrial DNA remains intact during Drosophila aging, but the levels of mitochondrial transcripts are significantly reduced. J Biol Chem 1993; 268:18891-18897.
-
(1993)
J Biol Chem
, vol.268
, pp. 18891-18897
-
-
Calleja, M.1
Pena, P.2
Ugalde, C.3
Ferreiro, C.4
Marco, R.5
Garesse, R.6
-
56
-
-
0029019546
-
Increased frequency of deletions in the mitochondrial genome with age of Caenorhabditis elegans
-
Melov S, Lithgow GJ, Fischer DR, Tedesco PM, Johnson TE. Increased frequency of deletions in the mitochondrial genome with age of Caenorhabditis elegans. Nucleic Acids Res 1995;23:1419-1425.
-
(1995)
Nucleic Acids Res
, vol.23
, pp. 1419-1425
-
-
Melov, S.1
Lithgow, G.J.2
Fischer, D.R.3
Tedesco, P.M.4
Johnson, T.E.5
-
57
-
-
0024541068
-
Mitochondrial DNA mutations and neuromuscular disease
-
Wallace DC. Mitochondrial DNA mutations and neuromuscular disease. Trends Genet 1989;5:9-13.
-
(1989)
Trends Genet
, vol.5
, pp. 9-13
-
-
Wallace, D.C.1
-
58
-
-
0025276996
-
Deletion mutants are functionally dominant over wild-type mitochondrial genomes in skeletal muscle fiber segments in mitochondrial disease
-
Shoubridge EA, Karpati G, Hastings KE. Deletion mutants are functionally dominant over wild-type mitochondrial genomes in skeletal muscle fiber segments in mitochondrial disease. Cell 1990;62:43-49.
-
(1990)
Cell
, vol.62
, pp. 43-49
-
-
Shoubridge, E.A.1
Karpati, G.2
Hastings, K.E.3
-
59
-
-
0002827532
-
Group report. the role of bioenergetics and mitochondrial DNA mutations in aging and age-related diseases
-
Esser K, Martin GM, eds. Chichester, UK: John Wiley & Sons
-
Wallace DC, Bohr VA, Cortopassi G, Kadenbach B, Linn S, Linnane AW, Richter C, Shay JW. Group report. The role of bioenergetics and mitochondrial DNA mutations in aging and age-related diseases, In: Esser K, Martin GM, eds. Molecular Aspects of Aging. Chichester, UK: John Wiley & Sons, 1995:199-225.
-
(1995)
Molecular Aspects of Aging
, pp. 199-225
-
-
Wallace, D.C.1
Bohr, V.A.2
Cortopassi, G.3
Kadenbach, B.4
Linn, S.5
Linnane, A.W.6
Richter, C.7
Shay, J.W.8
-
60
-
-
0032849153
-
The mitochondrial theory of aging: Do damaged mitochondria accumulate by delayed degradation?
-
Kowald A. The mitochondrial theory of aging: do damaged mitochondria accumulate by delayed degradation? Exp Gerontol 1999;34:605-612.
-
(1999)
Exp Gerontol
, vol.34
, pp. 605-612
-
-
Kowald, A.1
-
61
-
-
0031081410
-
A proposed refinement of the mitochondrial free radical theory of aging
-
de Grey ADNJ. A proposed refinement of the mitochondrial free radical theory of aging. BioEssays 1997;19:161-166.
-
(1997)
BioEssays
, vol.19
, pp. 161-166
-
-
De Grey, A.D.N.J.1
-
62
-
-
0027525966
-
Different in situ hybridization patterns of mitochondrial DNA in cytochrome c oxidase-deficient extraocular muscle fibres in the elderly
-
Müller-Höcker J, Seibel P, Schneiderbanger K, Kadenbach B. Different in situ hybridization patterns of mitochondrial DNA in cytochrome c oxidase-deficient extraocular muscle fibres in the elderly. Virchows Arch A 1993;422:7-15.
-
(1993)
Virchows Arch A
, vol.422
, pp. 7-15
-
-
Müller-Höcker, J.1
Seibel, P.2
Schneiderbanger, K.3
Kadenbach, B.4
-
63
-
-
0031885843
-
Role of mitochondrial DNA mutations in human aging: Implications for the central nervous system and muscle
-
Brierley EJ, Johnson MA, Lightowlers RN, James OF, Turnbull DM. Role of mitochondrial DNA mutations in human aging: implications for the central nervous system and muscle. Ann Neurol 1998;43:217-223.
-
(1998)
Ann Neurol
, vol.43
, pp. 217-223
-
-
Brierley, E.J.1
Johnson, M.A.2
Lightowlers, R.N.3
James, O.F.4
Turnbull, D.M.5
-
64
-
-
0032533691
-
Association of age-related mitochondrial abnormalities with skeletal muscle fiber atrophy
-
Lee CM, Lopez ME, Weindruch R, Aiken JM. Association of age-related mitochondrial abnormalities with skeletal muscle fiber atrophy. Free Radic Biol Med 1998;25:964-972.
-
(1998)
Free Radic Biol Med
, vol.25
, pp. 964-972
-
-
Lee, C.M.1
Lopez, M.E.2
Weindruch, R.3
Aiken, J.M.4
-
65
-
-
0033151863
-
Cell-by-cell scanning of whole mitochondrial genomes in aged human heart reveals a significant fraction of myocytes with clonally expanded deletions
-
Khrapko K, Bodyak N, Thilly WG, van Orsouw NJ, Zhang X, Coller HA, Perls TT, Upton M, Vijg J, Wei JY. Cell-by-cell scanning of whole mitochondrial genomes in aged human heart reveals a significant fraction of myocytes with clonally expanded deletions. Nucleic Acids Res 1999;27:2434-2441.
-
(1999)
Nucleic Acids Res
, vol.27
, pp. 2434-2441
-
-
Khrapko, K.1
Bodyak, N.2
Thilly, W.G.3
Van Orsouw, N.J.4
Zhang, X.5
Coller, H.A.6
Perls, T.T.7
Upton, M.8
Vijg, J.9
Wei, J.Y.10
-
66
-
-
0029824258
-
Exon shuffling and the origin of the mitochondrial targeting function in plant cytochrome c1 precursor
-
Long M, de Souza SJ, Rosenberg C, Gilbert W. Exon shuffling and the origin of the mitochondrial targeting function in plant cytochrome c1 precursor. Proc Natl Acad Sci USA 1996;93:7727-7731.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 7727-7731
-
-
Long, M.1
De Souza, S.J.2
Rosenberg, C.3
Gilbert, W.4
-
67
-
-
0015319592
-
The biologic clock: The mitochondria?
-
Harman D. The biologic clock: the mitochondria? J Am Geriatr Soc 1972;20:145-147.
-
(1972)
J Am Geriatr Soc
, vol.20
, pp. 145-147
-
-
Harman, D.1
-
68
-
-
0026469073
-
Analyses of mitochondrial respiratory chain function and mitochondrial DNA deletion in human skeletal muscle: Effect of ageing
-
Cooper JM, Mann VM, Schapira AHV. Analyses of mitochondrial respiratory chain function and mitochondrial DNA deletion in human skeletal muscle: effect of ageing. J Neurol Sci 1992;113:91-98.
-
(1992)
J Neurol Sci
, vol.113
, pp. 91-98
-
-
Cooper, J.M.1
Mann, V.M.2
Schapira, A.H.V.3
-
69
-
-
0030009436
-
Effects of physical activity and age on mitochondrial function
-
Brierley EJ, Johnson MA, James OF, Tumbull DM. Effects of physical activity and age on mitochondrial function. OJM 1996;89:251-258.
-
(1996)
OJM
, vol.89
, pp. 251-258
-
-
Brierley, E.J.1
Johnson, M.A.2
James, O.F.3
Tumbull, D.M.4
-
70
-
-
0028787717
-
Marked increase in the number and variety of mitochondrial DNA rearrangements in aging human skeletal muscle
-
Melov S, Shoffner JM, Kaufman A, Wallace DC. Marked increase in the number and variety of mitochondrial DNA rearrangements in aging human skeletal muscle. Nucleic Acids Res 1995;23:4122-4126.
-
(1995)
Nucleic Acids Res
, vol.23
, pp. 4122-4126
-
-
Melov, S.1
Shoffner, J.M.2
Kaufman, A.3
Wallace, D.C.4
-
72
-
-
0030582373
-
Age-related extensive fragmentation of mitochondrial DNA into minicircles
-
Hayakawa M, Katsumata K, Yoneda M, Tanaka M, Sugiyama S, Ozawa T. Age-related extensive fragmentation of mitochondrial DNA into minicircles. Biochem Biophys Res Commun 1996;226:369-377.
-
(1996)
Biochem Biophys Res Commun
, vol.226
, pp. 369-377
-
-
Hayakawa, M.1
Katsumata, K.2
Yoneda, M.3
Tanaka, M.4
Sugiyama, S.5
Ozawa, T.6
-
73
-
-
0024366601
-
Cytochrome-c-oxidase deficient cardiomyocytes in the human heart - An age-related phenomenon. A histochemical ultracytochemical study
-
Müller-Höcker J. Cytochrome-c-oxidase deficient cardiomyocytes in the human heart - an age-related phenomenon. A histochemical ultracytochemical study. Am J Pathol 1989;134:1167-1173.
-
(1989)
Am J Pathol
, vol.134
, pp. 1167-1173
-
-
Müller-Höcker, J.1
-
75
-
-
0002386563
-
A mechanism proposed to explain the rise in oxidative stress during aging
-
de Grey ADNJ. A mechanism proposed to explain the rise in oxidative stress during aging. J Anti-Aging Med 1998;1:53-66.
-
(1998)
J Anti-Aging Med
, vol.1
, pp. 53-66
-
-
De Grey, A.D.N.J.1
-
76
-
-
0033968516
-
The reductive hotspot hypothesis: An update
-
de Grey ADNJ. The reductive hotspot hypothesis: an update. Arch Biochem Biophys 2000;373:295-301.
-
(2000)
Arch Biochem Biophys
, vol.373
, pp. 295-301
-
-
De Grey, A.D.N.J.1
-
77
-
-
0027234431
-
Possible reversal of ageing and other mitochondrial deficiencies through retroviral transfection of mitochondrially encoded proteins to the nucleus
-
Hoeben P. Possible reversal of ageing and other mitochondrial deficiencies through retroviral transfection of mitochondrially encoded proteins to the nucleus. Med Hypotheses 1993;41:131-133.
-
(1993)
Med Hypotheses
, vol.41
, pp. 131-133
-
-
Hoeben, P.1
-
78
-
-
0008234131
-
Are those 13 proteins really unimportable?
-
Wagner E, Normann J, Greppin H, et al., eds. Geneva: Geneva University Press
-
de Grey ADNJ. Are those 13 proteins really unimportable? In: Wagner E, Normann J, Greppin H, et al., eds. From Symbiosis to Eukaryotism - Endocytobiology VII. Geneva: Geneva University Press, 1999:489-502.
-
(1999)
From Symbiosis to Eukaryotism - Endocytobiology VII
, pp. 489-502
-
-
De Grey, A.D.N.J.1
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