Observations on the use of triphenylphosphonium bromide as a mild and quantifiable source of hydrogen bromide for chemoselective ring opening of epoxides to bromohydrins

Synlett

Volumn , Issue 3, 2000, Pages 382-384

  Afonso, Carlos A M ^a   Vieira, Nuno M L ^a   Motherwell, William B ^b  

^a UNIVERSIDADE NOVA DE LISBOA   (Portugal)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Bromohydrins; Epoxide ring opening; Triphenylphosphonium bromide

Indexed keywords

EPOXIDE; HYDROBROMIC ACID; PHOSPHONIUM DERIVATIVE;

ARTICLE; CHEMICAL ANALYSIS; CHEMICAL REACTION; NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS; SYNTHESIS;

EID: 0034050783     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

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8. The spectral and physical data of the halohydrin products were identical in all respects with reported literature data. All new compounds gave spectroscopic (IR, NMR) and analytical data (combustion analyses or high resolution mass spectra) in agreement with the assigned structures.
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13. Grupta, A.K.; Kazlawskas, R.J. Tetrahedron Asymm. 1993, 4, 879. Guiridon, Y.; Therien, M.; Girard, Y.; Yoakim, C. J. Org. Chem. 1987, 52, 1680.