-
1
-
-
0344911075
-
Structure-activity relationships for 4-anilinoquinazoline and related pyridopyrimidine acrylamides as specific, irreversible inhibitors of the ATP site of the epidermal growth factor receptor
-
1. Denn WA, Smaill JB, Fry DW, et al. Structure-activity relationships for 4-anilinoquinazoline and related pyridopyrimidine acrylamides as specific, irreversible inhibitors of the ATP site of the epidermal growth factor receptor [abstract]. Proc Am Assoc Cancer Res 1998; 39: 559
-
(1998)
Proc Am Assoc Cancer Res
, vol.39
, pp. 559
-
-
Denn, W.A.1
Smaill, J.B.2
Fry, D.W.3
-
2
-
-
0002308879
-
The eukaryotic protein kinase superfamily
-
Hardie G, Hanks S, editors. New York: Academic Press
-
2. Hanks SK, Hunter T. The eukaryotic protein kinase superfamily. In: Hardie G, Hanks S, editors. The protein kinase facts book. New York: Academic Press, 1995; 7: 7-47
-
(1995)
The Protein Kinase Facts Book
, vol.7
, pp. 7-47
-
-
Hanks, S.K.1
Hunter, T.2
-
3
-
-
34347278257
-
The chemotherapy of malignant diseases: Research perspectives
-
Sedlacek HH, Hoffmann D, Schulz G, et al., editors. München: Karger Verlag
-
3. Sedlacek HH, Hoffmann D, Schulz G, et al. The chemotherapy of malignant diseases: research perspectives. In: Sedlacek HH, Hoffmann D, Schulz G, et al., editors. Contributions to Oncology No. 34. München: Karger Verlag, 1989
-
(1989)
Contributions to Oncology No. 34
-
-
Sedlacek, H.H.1
Hoffmann, D.2
Schulz, G.3
-
4
-
-
0027749347
-
Heregulin induces tyrosine phosphorylation of HER4/P180 (erbB4)
-
4. Plowman GD, Green JM, Culouscou JM, et al. Heregulin induces tyrosine phosphorylation of HER4/P180 (erbB4). Nature 1993; 366: 473-5
-
(1993)
Nature
, vol.366
, pp. 473-475
-
-
Plowman, G.D.1
Green, J.M.2
Culouscou, J.M.3
-
5
-
-
0027463545
-
Growth factors: Regulation of normal and neoplastic growth
-
5. Pusztal L, Lewis CE, Lorenzen J, et al. Growth factors: regulation of normal and neoplastic growth. J Pathol 1993; 169: 191-201
-
(1993)
J Pathol
, vol.169
, pp. 191-201
-
-
Pusztal, L.1
Lewis, C.E.2
Lorenzen, J.3
-
6
-
-
0026569437
-
Growth factors and tyrosine kinase receptors during development and cancer
-
6. Boyle WJ. Growth factors and tyrosine kinase receptors during development and cancer. Curr Opin Oncol 1992; 4: 156-62
-
(1992)
Curr Opin Oncol
, vol.4
, pp. 156-162
-
-
Boyle, W.J.1
-
7
-
-
0028935364
-
The phosphorylation connection to cancer
-
7. Boulikas T. The phosphorylation connection to cancer (review). Int J Oncol 1995; 6: 271-8
-
(1995)
Int J Oncol
, vol.6
, pp. 271-278
-
-
Boulikas, T.1
-
8
-
-
0020068317
-
A native 170 000 epidermal growth factor receptor-kinase complex from shed plasma membrane vesicles
-
8. Cohen S, Ushiro H, Stoscheck C, et al. A native 170 000 epidermal growth factor receptor-kinase complex from shed plasma membrane vesicles. J Biol Chem 1982; 257: 1523-31
-
(1982)
J Biol Chem
, vol.257
, pp. 1523-1531
-
-
Cohen, S.1
Ushiro, H.2
Stoscheck, C.3
-
9
-
-
0027229556
-
Grb2 mediates the EGF-dependent activation of guanine nucleotide exchange on Ras
-
9. Gale NW, Kaplan S, Lowenstein EJ, et al. Grb2 mediates the EGF-dependent activation of guanine nucleotide exchange on Ras. Nature 1993; 363: 88-90
-
(1993)
Nature
, vol.363
, pp. 88-90
-
-
Gale, N.W.1
Kaplan, S.2
Lowenstein, E.J.3
-
10
-
-
0028172067
-
T cells from renal cell carcinoma patients exhibit an abnormal pattern of kappa B-specific DNA-binding activity: A preliminary report
-
10. Li X, Liu J, Park JK, et al. T cells from renal cell carcinoma patients exhibit an abnormal pattern of kappa B-specific DNA-binding activity: a preliminary report. Cancer Res 1994; 54: 5424-9
-
(1994)
Cancer Res
, vol.54
, pp. 5424-5429
-
-
Li, X.1
Liu, J.2
Park, J.K.3
-
12
-
-
0025177324
-
Phosphorylation of GAP and GAP-associated proteins by transforming and mitogenic tyrosine kinases
-
12. Ellis C, Moran M, McCormick F, et al. Phosphorylation of GAP and GAP-associated proteins by transforming and mitogenic tyrosine kinases. Nature 1990; 343: 377-81
-
(1990)
Nature
, vol.343
, pp. 377-381
-
-
Ellis, C.1
Moran, M.2
McCormick, F.3
-
13
-
-
0025143144
-
Metabolism and the effects of epidermal growth factor and related growth factors in mammals
-
13. Fisher DA, Lakshmanan J. Metabolism and the effects of epidermal growth factor and related growth factors in mammals. Endocr Rev 1990 11: 418-45
-
(1990)
Endocr Rev
, vol.11
, pp. 418-445
-
-
Fisher, D.A.1
Lakshmanan, J.2
-
14
-
-
0023595325
-
Epidermal growth factor dependent transformation by a human EGF receptor protooncogene
-
14. Velu TJ, Beguinot L, Vass WC, et al. Epidermal growth factor dependent transformation by a human EGF receptor protooncogene. Science 1987; 238: 1408-10
-
(1987)
Science
, vol.238
, pp. 1408-1410
-
-
Velu, T.J.1
Beguinot, L.2
Vass, W.C.3
-
15
-
-
0021281324
-
Close similarity of epidermal growth factor receptor and v-erbB oncogene protein sequence
-
15. Downward J, Yarden Y, Mayes E, et al. Close similarity of epidermal growth factor receptor and v-erbB oncogene protein sequence. Nature 1984; 307: 521-7
-
(1984)
Nature
, vol.307
, pp. 521-527
-
-
Downward, J.1
Yarden, Y.2
Mayes, E.3
-
16
-
-
0021140954
-
Epidermal growth factor binding by breast tumor biopsies and relationship to estrogen and progestin receptor levels
-
16. Fitzpatrick SL, Brightwell J, Wittliff J, et al. Epidermal growth factor binding by breast tumor biopsies and relationship to estrogen and progestin receptor levels. Cancer Res 1984; 44: 3448-53
-
(1984)
Cancer Res
, vol.44
, pp. 3448-3453
-
-
Fitzpatrick, S.L.1
Brightwell, J.2
Wittliff, J.3
-
17
-
-
0026571910
-
The clinical significance of epidermal growth factor receptor (EGF-R) in human breast cancer: A review on 5232 patients
-
17. Klijn JGM, Berns PMJJ, Schmitz PIM, et al. The clinical significance of epidermal growth factor receptor (EGF-R) in human breast cancer: a review on 5232 patients. Endocr Rev 1992; 13: 3-15
-
(1992)
Endocr Rev
, vol.13
, pp. 3-15
-
-
Klijn, J.G.M.1
Berns, P.M.J.J.2
Schmitz, P.I.M.3
-
18
-
-
0028955388
-
Epidermal growth factor-related peptides and their receptors in human malignancies
-
18. Salomon DS, Brandt R, Ciardiello F, et al. Epidermal growth factor-related peptides and their receptors in human malignancies. Crit Rev Oncol 1995; 19: 183-232
-
(1995)
Crit Rev Oncol
, vol.19
, pp. 183-232
-
-
Salomon, D.S.1
Brandt, R.2
Ciardiello, F.3
-
20
-
-
0026316096
-
Growth factors and cancer
-
20. Aaronson SA. Growth factors and cancer. Science 1991; 254: 1145-53
-
(1991)
Science
, vol.254
, pp. 1145-1153
-
-
Aaronson, S.A.1
-
21
-
-
0024950999
-
6]-luteinizing hormone-releasing hormone, somatostatin, epidermal growth factor and sex steroids in 500 biopsy samples of human breast cancer
-
6]-luteinizing hormone-releasing hormone, somatostatin, epidermal growth factor and sex steroids in 500 biopsy samples of human breast cancer. J Clin Lab Anal 1989; 3: 137-47
-
(1989)
J Clin Lab Anal
, vol.3
, pp. 137-147
-
-
Fekete, M.1
Wittliff, J.L.2
Schally, A.V.3
-
22
-
-
0025317908
-
6]-luteinizing hormone-releasing hormone and epidermal growth factor in human endometrial carcinoma
-
6]-luteinizing hormone-releasing hormone and epidermal growth factor in human endometrial carcinoma. Cancer Res 1990; 50: 1841-6
-
(1990)
Cancer Res
, vol.50
, pp. 1841-1846
-
-
Srkalovic, G.1
Wittliff, J.L.2
Schally, A.V.3
-
23
-
-
0343620855
-
Enhanced expression of epidermal growth factor receptor correlates with alterations of chromosome 7 in human pancreatic cancer
-
23. Korc M, Meltzer P, Trent J. Enhanced expression of epidermal growth factor receptor correlates with alterations of chromosome 7 in human pancreatic cancer. Proc Natl Acad Sci U S A 1986; 83: 5141-4
-
(1986)
Proc Natl Acad Sci U S A
, vol.83
, pp. 5141-5144
-
-
Korc, M.1
Meltzer, P.2
Trent, J.3
-
24
-
-
0025111441
-
A deletion mutation within the ligand binding domain is responsible for activation of epidermal growth factor gene in human brain tumors
-
24. Yamazaki H, Ohba Y, Tamaoki N, et al. A deletion mutation within the ligand binding domain is responsible for activation of epidermal growth factor gene in human brain tumors. Jpn J Cancer Res 1990; 81: 773-9
-
(1990)
Jpn J Cancer Res
, vol.81
, pp. 773-779
-
-
Yamazaki, H.1
Ohba, Y.2
Tamaoki, N.3
-
25
-
-
0028800035
-
Frequent expression of a mutant epidermal growth factor receptor in multiple human tumors
-
25. Moscatello DK, Holgado-Madruga M, Godwin AK, et al. Frequent expression of a mutant epidermal growth factor receptor in multiple human tumors. Cancer Res 1995; 55: 5536-9
-
(1995)
Cancer Res
, vol.55
, pp. 5536-5539
-
-
Moscatello, D.K.1
Holgado-Madruga, M.2
Godwin, A.K.3
-
26
-
-
0029025332
-
Monoclonal antibodies against EGFRvIII are tumor specific and react with breast and lung carcinomas and malignant gliomas
-
26. Wickstrand CJ, Hale LP, Batra SK, et al. Monoclonal antibodies against EGFRvIII are tumor specific and react with breast and lung carcinomas and malignant gliomas. Cancer Res 1995; 55: 3140-8
-
(1995)
Cancer Res
, vol.55
, pp. 3140-3148
-
-
Wickstrand, C.J.1
Hale, L.P.2
Batra, S.K.3
-
27
-
-
0027516706
-
IRS-1 is a common element in insulin and insulin-like growth factor-1 signalling to the phosphatidylinositol 3′-kinase
-
27. Myers MG, Sun XJ, Cheatham B, et al. IRS-1 is a common element in insulin and insulin-like growth factor-1 signalling to the phosphatidylinositol 3′-kinase. Endocrinol 1993; 132: 1421-30
-
(1993)
Endocrinol
, vol.132
, pp. 1421-1430
-
-
Myers, M.G.1
Sun, X.J.2
Cheatham, B.3
-
28
-
-
0025708183
-
p185neu expression in human lung adenocarcinomas predicts shortened survival
-
28. Kern JA, Schwartz DA, Nordberg JE, et al. p185neu expression in human lung adenocarcinomas predicts shortened survival. Cancer Res 1990; 50: 5184-8
-
(1990)
Cancer Res
, vol.50
, pp. 5184-5188
-
-
Kern, J.A.1
Schwartz, D.A.2
Nordberg, J.E.3
-
29
-
-
0025195896
-
The c-erb B-2 protooncogene in human pancreatic cancer
-
29. Hall PA, Hughes CM, Staddon SL, et al. The c-erb B-2 protooncogene in human pancreatic cancer. J Pathol 1990; 161: 195-200
-
(1990)
J Pathol
, vol.161
, pp. 195-200
-
-
Hall, P.A.1
Hughes, C.M.2
Staddon, S.L.3
-
30
-
-
0026098279
-
Overexpression of HER-2/neu in endometrial cancer is associated with advanced stage disease
-
30. Berchuck A, Rodriguez G, Kinney RB, et al. Overexpression of HER-2/neu in endometrial cancer is associated with advanced stage disease. Am J Obstet Gynecol 1991; 164: 15-21
-
(1991)
Am J Obstet Gynecol
, vol.164
, pp. 15-21
-
-
Berchuck, A.1
Rodriguez, G.2
Kinney, R.B.3
-
31
-
-
0013634502
-
Multiple independent activation of the neu oncogene by point mutations altering the transmembrane domain of p185
-
31. Bergman CL, Hung MC, Weinberg RA. Multiple independent activation of the neu oncogene by point mutations altering the transmembrane domain of p185. Cell 1984; 46: 649-57
-
(1984)
Cell
, vol.46
, pp. 649-657
-
-
Bergman, C.L.1
Hung, M.C.2
Weinberg, R.A.3
-
32
-
-
0027496195
-
Paracrine growth regulation of human colon carcinoma organ-specific metastasis
-
32. Radinsky R. Paracrine growth regulation of human colon carcinoma organ-specific metastasis. Cancer Metast Rev 1993; 12: 345-61
-
(1993)
Cancer Metast Rev
, vol.12
, pp. 345-361
-
-
Radinsky, R.1
-
33
-
-
0027365931
-
Aberrant expression of the type I fibroblast growth factor receptor in human pancreatic adenocarcinomas
-
33. Kobrin MS, Yamanaka Y, Friess H, et al. Aberrant expression of the type I fibroblast growth factor receptor in human pancreatic adenocarcinomas. Cancer Res 1993; 53: 4741-4
-
(1993)
Cancer Res
, vol.53
, pp. 4741-4744
-
-
Kobrin, M.S.1
Yamanaka, Y.2
Friess, H.3
-
34
-
-
0028802802
-
Growth factors and their receptors in neoplastic mammary glands
-
34. Rudland PS, Fernig DG, Smith JA. Growth factors and their receptors in neoplastic mammary glands. Biomed Pharmacother 1995; 49: 389-99
-
(1995)
Biomed Pharmacother
, vol.49
, pp. 389-399
-
-
Rudland, P.S.1
Fernig, D.G.2
Smith, J.A.3
-
35
-
-
0026654777
-
Basic fibroblast growth factor production and growth factor receptors as potential targets for melanoma therapy
-
35. Kato J, Wanebo H, Calabresi P, et al. Basic fibroblast growth factor production and growth factor receptors as potential targets for melanoma therapy. Melanoma Res 1992; 2: 13-23
-
(1992)
Melanoma Res
, vol.2
, pp. 13-23
-
-
Kato, J.1
Wanebo, H.2
Calabresi, P.3
-
36
-
-
0028179757
-
Autocrine and paracrine roles for growth factors in melanoma
-
36. Shih IM, Herlyn M. Autocrine and paracrine roles for growth factors in melanoma. In Vivo 1994; 8: 113-24
-
(1994)
In Vivo
, vol.8
, pp. 113-124
-
-
Shih, I.M.1
Herlyn, M.2
-
37
-
-
0028998669
-
Insulin-like growth factors in breast and prostatic cancer
-
37. Helle SI, Lonning PE. Insulin-like growth factors in breast and prostatic cancer. Endocr Relat Cancer 1995; 2: 153-69
-
(1995)
Endocr Relat Cancer
, vol.2
, pp. 153-169
-
-
Helle, S.I.1
Lonning, P.E.2
-
38
-
-
0026576726
-
Insulin-like growth factors and cancer
-
38. Macaulay VM. Insulin-like growth factors and cancer. Br J Cancer 1992; 65: 311-20
-
(1992)
Br J Cancer
, vol.65
, pp. 311-320
-
-
Macaulay, V.M.1
-
39
-
-
0028997487
-
Insulin-like growth factor 1 overexpression in human pancreatic cancer: Evidence for autocrine and paracrine roles
-
39. Bergmann U, Funtomi H, Yokoyama M, et al. Insulin-like growth factor 1 overexpression in human pancreatic cancer: evidence for autocrine and paracrine roles. Cancer Res 1995; 55: 2007-11
-
(1995)
Cancer Res
, vol.55
, pp. 2007-2011
-
-
Bergmann, U.1
Funtomi, H.2
Yokoyama, M.3
-
40
-
-
0029995770
-
Controlling IGF-receptor function: A possible strategy for tumor therapy
-
40. Baserga R. Controlling IGF-receptor function: a possible strategy for tumor therapy. Tibtech 1996; 14: 150
-
(1996)
Tibtech
, vol.14
, pp. 150
-
-
Baserga, R.1
-
41
-
-
0030008955
-
Insulin receptor substrate I overexpression in human hepatocellular carcinoma cells prevents transforming growth factor β1-induced apoptosis
-
41. Tanaka S, Wands JR. Insulin receptor substrate I overexpression in human hepatocellular carcinoma cells prevents transforming growth factor β1-induced apoptosis. Cancer Res 1996; 56: 3391-4
-
(1996)
Cancer Res
, vol.56
, pp. 3391-3394
-
-
Tanaka, S.1
Wands, J.R.2
-
42
-
-
0027481970
-
Growth factors and their receptors as determinants in the proliferation and metastasis of human prostate cancer
-
42. Ware JL. Growth factors and their receptors as determinants in the proliferation and metastasis of human prostate cancer. Cancer Metast Rev 1993; 12: 287-301
-
(1993)
Cancer Metast Rev
, vol.12
, pp. 287-301
-
-
Ware, J.L.1
-
43
-
-
0023500107
-
Metastatic but not primary melanoma cells grow in vitro independently of exogenous growth factors
-
43. Rodeck U, Herlyn M, Menssen HD, et al. Metastatic but not primary melanoma cells grow in vitro independently of exogenous growth factors. Int J Cancer 1987; 40: 687-90
-
(1987)
Int J Cancer
, vol.40
, pp. 687-690
-
-
Rodeck, U.1
Herlyn, M.2
Menssen, H.D.3
-
44
-
-
0028793112
-
Insulin-like growth factors and breast cancer
-
44. Lee AV, Yee D. Insulin-like growth factors and breast cancer. Biomed Pharmacother 1995; 49: 415-21
-
(1995)
Biomed Pharmacother
, vol.49
, pp. 415-421
-
-
Lee, A.V.1
Yee, D.2
-
45
-
-
0027392784
-
Growth factor and peptide receptors in small cell lung cancer
-
45. Moody TW, Guttitta F. Growth factor and peptide receptors in small cell lung cancer. Life Sci 1993; 52: 1161-73
-
(1993)
Life Sci
, vol.52
, pp. 1161-1173
-
-
Moody, T.W.1
Guttitta, F.2
-
46
-
-
0029119731
-
Insulin-like growth factor-1 receptor: Its role in cell proliferation, apoptosis, and tumorigenicity
-
46. Rubin R, Baserga R. Insulin-like growth factor-1 receptor: its role in cell proliferation, apoptosis, and tumorigenicity. Lab Invest 1995; 73: 311-31
-
(1995)
Lab Invest
, vol.73
, pp. 311-331
-
-
Rubin, R.1
Baserga, R.2
-
47
-
-
0025764960
-
c-met is amplified but not mutated in a cell line with an activated met tyrosine kinase
-
47. Ponzetto C, Giordano S, Della Valle G, et al. c-met is amplified but not mutated in a cell line with an activated met tyrosine kinase. Oncogene 1991; 6: 553-9
-
(1991)
Oncogene
, vol.6
, pp. 553-559
-
-
Ponzetto, C.1
Giordano, S.2
Della Valle, G.3
-
48
-
-
0026448347
-
Met and hepatocyte growth factor/scatter factor signal transduction in normal melanocytes and melanoma cells
-
48. Halaban R, Rubin JS, Funasaka Y, et al. Met and hepatocyte growth factor/scatter factor signal transduction in normal melanocytes and melanoma cells. Oncogene 1992; 7: 2195-206
-
(1992)
Oncogene
, vol.7
, pp. 2195-2206
-
-
Halaban, R.1
Rubin, J.S.2
Funasaka, Y.3
-
49
-
-
0028941747
-
Expression of the met/hepatocyte growth factor receptor in human pancreatic cancer
-
49. DiRenzo MF, Poulsom R, Olivero M, et al. Expression of the met/hepatocyte growth factor receptor in human pancreatic cancer. Cancer Res 1995; 55: 1129-38
-
(1995)
Cancer Res
, vol.55
, pp. 1129-1138
-
-
DiRenzo, M.F.1
Poulsom, R.2
Olivero, M.3
-
50
-
-
0026441272
-
Overexpression of the c-MET/HGF receptor gene in human thyroid carcinomas
-
50. DiRenzo MF, Olivero M, Ferro S, et al. Overexpression of the c-MET/HGF receptor gene in human thyroid carcinomas. Oncogene 1992; 7: 2549-53
-
(1992)
Oncogene
, vol.7
, pp. 2549-2553
-
-
DiRenzo, M.F.1
Olivero, M.2
Ferro, S.3
-
51
-
-
0024829313
-
The type I insulin-like growth factor receptor is a motility receptor in human melanoma cells
-
51. Stracke ML, Engel JD, Wilson LW, et al. The type I insulin-like growth factor receptor is a motility receptor in human melanoma cells. J Biol Chem 1989; 264: 21544-9
-
(1989)
J Biol Chem
, vol.264
, pp. 21544-21549
-
-
Stracke, M.L.1
Engel, J.D.2
Wilson, L.W.3
-
52
-
-
0028107269
-
Expression and function of TRK-B and BDNF in human neuroblastomas
-
52. Nakagawara A, Azar CG, Scavarda NJ, et al. Expression and function of TRK-B and BDNF in human neuroblastomas. Mol Cell Biol 1994; 14: 759-67
-
(1994)
Mol Cell Biol
, vol.14
, pp. 759-767
-
-
Nakagawara, A.1
Azar, C.G.2
Scavarda, N.J.3
-
53
-
-
0026772431
-
Platelet-derived growth factor and its receptors in human glioma tissue: Expression of messenger RNA and protein suggests the presence of autocrine and paracrine loops
-
53. Hermansson M, Funa K, Hartman M, et al. Platelet-derived growth factor and its receptors in human glioma tissue: expression of messenger RNA and protein suggests the presence of autocrine and paracrine loops. Cancer Res 1992; 52: 3213-9
-
(1992)
Cancer Res
, vol.52
, pp. 3213-3219
-
-
Hermansson, M.1
Funa, K.2
Hartman, M.3
-
54
-
-
0021355525
-
A glioma-derived analog to platelet-derived growth factor: Demonstration of receptor dompeting activity and immunological crossreactivity
-
54. Nister M, Heldin CH, Wasteson A, et al. A glioma-derived analog to platelet-derived growth factor: demonstration of receptor dompeting activity and immunological crossreactivity. Proc Natl Acad Sci U S A 1984; 81: 926-30
-
(1984)
Proc Natl Acad Sci U S A
, vol.81
, pp. 926-930
-
-
Nister, M.1
Heldin, C.H.2
Wasteson, A.3
-
55
-
-
0023747564
-
Expression of messenger RNAs for platelet-derived growth factor and transforming growth factor-alpha and their receptors in human malignant glioma cell lines
-
55. Nister M, Libermann TA, Betsholtz C, et al. Expression of messenger RNAs for platelet-derived growth factor and transforming growth factor-alpha and their receptors in human malignant glioma cell lines. Cancer Res 1988; 48: 3910-8
-
(1988)
Cancer Res
, vol.48
, pp. 3910-3918
-
-
Nister, M.1
Libermann, T.A.2
Betsholtz, C.3
-
56
-
-
0242385220
-
cDNA cloning and expression of the human A-type platelet-derived growth factor (PDGF) receptor establishes structural similarity of the B-type PDGF receptor
-
56. Claesson-Welsh L, Eriksson A, Westermark B, et al. cDNA cloning and expression of the human A-type platelet-derived growth factor (PDGF) receptor establishes structural similarity of the B-type PDGF receptor. Proc Natl Acad Sci U S A 1989; 86: 4917-21
-
(1989)
Proc Natl Acad Sci U S A
, vol.86
, pp. 4917-4921
-
-
Claesson-Welsh, L.1
Eriksson, A.2
Westermark, B.3
-
57
-
-
0022655932
-
A human osteosarcoma cell line secretes a growth factor structurally related to a homodimer of PDGF A-chains
-
57. Heldin CH, Johnsson A, Wennergren S, et l. A human osteosarcoma cell line secretes a growth factor structurally related to a homodimer of PDGF A-chains. Nature 1986; 310: 511-4
-
(1986)
Nature
, vol.310
, pp. 511-514
-
-
Heldin, C.H.1
Johnsson, A.2
Wennergren, S.3
-
58
-
-
0025634167
-
Expression of messenger RNAs for platelet-derived growth factor and its receptors in human sarcoma cell lines
-
58. Leveen P, Claesson-Welsh L, Heldin CH, et al. Expression of messenger RNAs for platelet-derived growth factor and its receptors in human sarcoma cell lines. Int J Cancer 1990; 46: 1066-70
-
(1990)
Int J Cancer
, vol.46
, pp. 1066-1070
-
-
Leveen, P.1
Claesson-Welsh, L.2
Heldin, C.H.3
-
59
-
-
0025055311
-
Cultured Kaposi's sarcoma-derived cells express functional PDGF A-type and B-type receptors
-
59. Werner S, Hofschneider PH, Heldin CH, et al. Cultured Kaposi's sarcoma-derived cells express functional PDGF A-type and B-type receptors. Exp Cell Res 1990; 187: 98-103
-
(1990)
Exp Cell Res
, vol.187
, pp. 98-103
-
-
Werner, S.1
Hofschneider, P.H.2
Heldin, C.H.3
-
60
-
-
0023951703
-
Evidence of autocrine regulation in human hepatoma cell lines
-
60. Tsai TF, Yauk YK, Chou CK, et al. Evidence of autocrine regulation in human hepatoma cell lines. Biochem Biophys Res Commun 1988; 153: 39-45
-
(1988)
Biochem Biophys Res Commun
, vol.153
, pp. 39-45
-
-
Tsai, T.F.1
Yauk, Y.K.2
Chou, C.K.3
-
61
-
-
0025216780
-
Growth-regulatory factors for normal, premalignant, and malignant human cells in vitro
-
61. Herlyn M, Kath R, Williams N, et l. Growth-regulatory factors for normal, premalignant, and malignant human cells in vitro. Adv Cancer Res 1990; 54: 213-34
-
(1990)
Adv Cancer Res
, vol.54
, pp. 213-234
-
-
Herlyn, M.1
Kath, R.2
Williams, N.3
-
62
-
-
0025161251
-
Expression of several growth factors and their receptor genes in human colon carcinomas
-
62. Ito M, Yoshida K, Kyo E, et al. Expression of several growth factors and their receptor genes in human colon carcinomas. Virchows Archiv B Cell Pathol 1990; 59: 173-8
-
(1990)
Virchows Archiv B Cell Pathol
, vol.59
, pp. 173-178
-
-
Ito, M.1
Yoshida, K.2
Kyo, E.3
-
63
-
-
0023233104
-
Synthesis of PDGF by cultured human T cells transformed with HTLV-I and II
-
63. Pantazis P, Sariban E, Bohan CA, et al. Synthesis of PDGF by cultured human T cells transformed with HTLV-I and II. Oncogene 1987; 1: 285-9
-
(1987)
Oncogene
, vol.1
, pp. 285-289
-
-
Pantazis, P.1
Sariban, E.2
Bohan, C.A.3
-
64
-
-
0026060939
-
Coexpression of the genes for platelet-derived growth factor B-chain receptor and macrophage colony-stimulating factor 1 receptor during monocytic differentiation
-
64. Pantazis P, Kharbanda S, Goustin AS, et al. Coexpression of the genes for platelet-derived growth factor B-chain receptor and macrophage colony-stimulating factor 1 receptor during monocytic differentiation. Proc Natl Acad Sci U S A 1991; 88: 2481-5
-
(1991)
Proc Natl Acad Sci U S A
, vol.88
, pp. 2481-2485
-
-
Pantazis, P.1
Kharbanda, S.2
Goustin, A.S.3
-
65
-
-
0023551253
-
Regulation of platelet-derived growth factor gene expression by transforming growth factor beta and phorbol ester in human leukemia cell lines
-
65. Mäkelä TP, Alitalo R, Paulsson Y, et al. Regulation of platelet-derived growth factor gene expression by transforming growth factor beta and phorbol ester in human leukemia cell lines. Mol Cell Biol 1987; 7: 3656-62
-
(1987)
Mol Cell Biol
, vol.7
, pp. 3656-3662
-
-
Mäkelä, T.P.1
Alitalo, R.2
Paulsson, Y.3
-
66
-
-
0025285783
-
Human meningiomas co-express platelet-derived growth factor (PDGF) and PDGF-receptor genes and their protein products
-
66. Maxwell M, Galanopoulos T, Hedley-Whyte ET, et al. Human meningiomas co-express platelet-derived growth factor (PDGF) and PDGF-receptor genes and their protein products. Int J Cancer 1990; 46: 16-21
-
(1990)
Int J Cancer
, vol.46
, pp. 16-21
-
-
Maxwell, M.1
Galanopoulos, T.2
Hedley-Whyte, E.T.3
-
67
-
-
0023225322
-
Frequent expression of growth factors for mesenchymal cells in human mammary carcinoma cell lines
-
67. Peres R, Betsholtz C, Westermark B, et al. Frequent expression of growth factors for mesenchymal cells in human mammary carcinoma cell lines. Cancer Res 1987; 47: 3425-9
-
(1987)
Cancer Res
, vol.47
, pp. 3425-3429
-
-
Peres, R.1
Betsholtz, C.2
Westermark, B.3
-
68
-
-
0025829312
-
Stimulation of growth of human breast cancer cells (T47D) by platelet derived growth factor
-
68. Ginsburg E, Vonderhaar BK. Stimulation of growth of human breast cancer cells (T47D) by platelet derived growth factor. Cancer Lett 1991; 58: 137-44
-
(1991)
Cancer Lett
, vol.58
, pp. 137-144
-
-
Ginsburg, E.1
Vonderhaar, B.K.2
-
70
-
-
0023137380
-
Cultured human endothelial cells express platelet-derived growth factor A chain
-
70. Collins T, Pober JS, Gimbrone MA, et al. Cultured human endothelial cells express platelet-derived growth factor A chain. Am J Pathol 1987; 126: 7-12
-
(1987)
Am J Pathol
, vol.126
, pp. 7-12
-
-
Collins, T.1
Pober, J.S.2
Gimbrone, M.A.3
-
71
-
-
0024272031
-
A point mutation in the extracellular domain of the human CSF-1 receptor (Fms proto-oncogene product) activates its transforming potential
-
71. Roussel MF, Downing JR, Rettenmier CW, et al. A point mutation in the extracellular domain of the human CSF-1 receptor (Fms proto-oncogene product) activates its transforming potential. Cell 1988; 55: 979-88
-
(1988)
Cell
, vol.55
, pp. 979-988
-
-
Roussel, M.F.1
Downing, J.R.2
Rettenmier, C.W.3
-
72
-
-
0030758891
-
Modulation of c-fms proto-oncogene in an ovarian carcinoma cell line by a hammerhead ribozyme
-
72. Yokoyama Y, Morishita S, Takahashi Y, et al. Modulation of c-fms proto-oncogene in an ovarian carcinoma cell line by a hammerhead ribozyme. Br J Cancer 1997; 76: 977-82
-
(1997)
Br J Cancer
, vol.76
, pp. 977-982
-
-
Yokoyama, Y.1
Morishita, S.2
Takahashi, Y.3
-
73
-
-
0029986581
-
Expression of c-fms proto-oncogene product by ovarian cancer cell lines with effects of macrophage colony-stimulating factor on proliferation
-
73. Suzuki M, Sekiguchi I, Ohwada M, et al. Expression of c-fms proto-oncogene product by ovarian cancer cell lines with effects of macrophage colony-stimulating factor on proliferation. Oncology 1996; 53: 99-103
-
(1996)
Oncology
, vol.53
, pp. 99-103
-
-
Suzuki, M.1
Sekiguchi, I.2
Ohwada, M.3
-
74
-
-
0028839045
-
Transcriptional regulation of the c-fms (CSF-1R) proto-oncogene in human breast carcinoma cells by glucocorticoids
-
74. Sapi E, Flick MB, Gilmore-Hebert M, et al. Transcriptional regulation of the c-fms (CSF-1R) proto-oncogene in human breast carcinoma cells by glucocorticoids. Oncogene 1995; 10: 529-42
-
(1995)
Oncogene
, vol.10
, pp. 529-542
-
-
Sapi, E.1
Flick, M.B.2
Gilmore-Hebert, M.3
-
75
-
-
0027965744
-
Post-transcriptional regulation of c-fms proto-oncogene expression by dexamethasone and of CSF-1 in human breast carcinomas in vitro
-
75. Chambers SK, Wang Y, Gilmore-Hebert M, et al. Post-transcriptional regulation of c-fms proto-oncogene expression by dexamethasone and of CSF-1 in human breast carcinomas in vitro. Steroids 1994; 59: 514-22
-
(1994)
Steroids
, vol.59
, pp. 514-522
-
-
Chambers, S.K.1
Wang, Y.2
Gilmore-Hebert, M.3
-
76
-
-
0027732158
-
Expression of colony-stimulating factor-1 and its receptor (the protein product of c-fms) in invasive breast tumor cells: Induction of urokinase production via this pathway?
-
76. Scholl SM, Mosseri V, Tang R, et al. Expression of colony-stimulating factor-1 and its receptor (the protein product of c-fms) in invasive breast tumor cells: induction of urokinase production via this pathway? Ann N Y Acad Sci 1993; 698: 131-5
-
(1993)
Ann N Y Acad Sci
, vol.698
, pp. 131-135
-
-
Scholl, S.M.1
Mosseri, V.2
Tang, R.3
-
77
-
-
0025821436
-
FMS (CSF-1 receptor) and CSF-1 transcripts and protein are expressed by human breast carcinomas in vivo and in vitro
-
77. Kacinski BM, Scata KA, Carter D, et al. FMS (CSF-1 receptor) and CSF-1 transcripts and protein are expressed by human breast carcinomas in vivo and in vitro. Oncogene 1991; 6: 941-52
-
(1991)
Oncogene
, vol.6
, pp. 941-952
-
-
Kacinski, B.M.1
Scata, K.A.2
Carter, D.3
-
78
-
-
0027280804
-
The protooncogene c-fms is overexpressed in endometrial cancer
-
78. Leiserowitz GS, Harris SA, Subramaniam M, et al. The protooncogene c-fms is overexpressed in endometrial cancer. Gynecol Oncol 1993; 49: 190-6
-
(1993)
Gynecol Oncol
, vol.49
, pp. 190-196
-
-
Leiserowitz, G.S.1
Harris, S.A.2
Subramaniam, M.3
-
79
-
-
0026672068
-
c-fms is present in primary tumours as well as in their metastases in bone marrow
-
79. Storga D, Pecina-Slaus N, Pavelic J, et al. c-fms is present in primary tumours as well as in their metastases in bone marrow. Int J Exp Pathol 1992; 73: 527-33
-
(1992)
Int J Exp Pathol
, vol.73
, pp. 527-533
-
-
Storga, D.1
Pecina-Slaus, N.2
Pavelic, J.3
-
80
-
-
0023989811
-
Primary structure of cKit: Relationship with the CSF-1/PDGF receptor kinase family. Oncogenic activation of vKit involves deletion of extracellular domain and C-terminus
-
80. Qui F, Ray R, Brown K, et al. Primary structure of cKit: relationship with the CSF-1/PDGF receptor kinase family. Oncogenic activation of vKit involves deletion of extracellular domain and C-terminus. EMBO J 1988; 7: 1003-11
-
(1988)
EMBO J
, vol.7
, pp. 1003-1011
-
-
Qui, F.1
Ray, R.2
Brown, K.3
-
81
-
-
0027102715
-
c-kit-kinase induces a cascade of protein tyrosine phosphorylation in normal human melanocytes in response to mast cell growth factor in stimulates mitogen-activated protein kinase but is down-regulated in melanomas
-
81. Funasaka Y, Boulton T, Cobb M, et al. c-kit-kinase induces a cascade of protein tyrosine phosphorylation in normal human melanocytes in response to mast cell growth factor in stimulates mitogen-activated protein kinase but is down-regulated in melanomas. Mol Biol Cell 1992; 3: 197-209
-
(1992)
Mol Biol Cell
, vol.3
, pp. 197-209
-
-
Funasaka, Y.1
Boulton, T.2
Cobb, M.3
-
82
-
-
0026793058
-
Progression of human cutaneous melanoma is associated with loss of expression of c-kit proto-oncogene receptor
-
82. Natali PG, Nicotra MR, Winkler AB, et al. Progression of human cutaneous melanoma is associated with loss of expression of c-kit proto-oncogene receptor. Int J Cancer 1992; 52: 197-201
-
(1992)
Int J Cancer
, vol.52
, pp. 197-201
-
-
Natali, P.G.1
Nicotra, M.R.2
Winkler, A.B.3
-
83
-
-
0026518279
-
Loss of c-kit expression in cultured melanoma cells
-
83. Lassam N, Bickford S. Loss of c-kit expression in cultured melanoma cells. Oncogene 1992; 7: 51-6
-
(1992)
Oncogene
, vol.7
, pp. 51-56
-
-
Lassam, N.1
Bickford, S.2
-
84
-
-
0027981075
-
Vascular endothelial growth factor receptor localization and activation in human lrophoblast and choriocarcinoma cells
-
84. Charnock-Jones DS, Sharkey AM, Boocock AM, et al. Vascular endothelial growth factor receptor localization and activation in human lrophoblast and choriocarcinoma cells. Biol Reproduct 1994; 51: 524-30
-
(1994)
Biol Reproduct
, vol.51
, pp. 524-530
-
-
Charnock-Jones, D.S.1
Sharkey, A.M.2
Boocock, A.M.3
-
85
-
-
0027326476
-
Human melanoma cells but not nor normal melanocytes express vascular endothelial growth factor receptors
-
85. Gitay-Goren H., Halaban R, Neufeld G, et al. Human melanoma cells but not nor normal melanocytes express vascular endothelial growth factor receptors. Biochem Biophys Res Commun 1993; 190: 702-9
-
(1993)
Biochem Biophys Res Commun
, vol.190
, pp. 702-709
-
-
Gitay-Goren, H.1
Halaban, R.2
Neufeld, G.3
-
86
-
-
0028904030
-
Expression of vascular endothelial growth factor and its receptors flt and KDR in ovarian carcinoma
-
86. Boocock CA, Charnock-Jones DS, Sharkey AM, et al. Expression of vascular endothelial growth factor and its receptors flt and KDR in ovarian carcinoma. J Natl Cancer Inst 1995; 87: 506-16
-
(1995)
J Natl Cancer Inst
, vol.87
, pp. 506-516
-
-
Boocock, C.A.1
Charnock-Jones, D.S.2
Sharkey, A.M.3
-
87
-
-
0027768808
-
Increased expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in kidney and bladder carcinomas
-
87. Brown LF, Berse B, Jackman RW, et al. Increased expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in kidney and bladder carcinomas. Am J Pathol 1993; 143: 1255-62
-
(1993)
Am J Pathol
, vol.143
, pp. 1255-1262
-
-
Brown, L.F.1
Berse, B.2
Jackman, R.W.3
-
88
-
-
0028129426
-
Vascular endothelial growth factor induces the disorganization of actin stress fibers accompanied by protein tyrosine phosphorylation and morphological change in Balb/C3T3 cells
-
88. Enomoto T, Okamoto T, Sato JD. Vascular endothelial growth factor induces the disorganization of actin stress fibers accompanied by protein tyrosine phosphorylation and morphological change in Balb/C3T3 cells. Biochem Biophy Res Commun 1994; 202: 1716-23
-
(1994)
Biochem Biophy Res Commun
, vol.202
, pp. 1716-1723
-
-
Enomoto, T.1
Okamoto, T.2
Sato, J.D.3
-
89
-
-
0028880305
-
Expression of the vascular endothelial growth factor (VEGF) receptor gene, KDR, in hematopoietic cells and inhibitory effect of VEGF on apoptotic cell death caused by ionizing radiation
-
89. Katoh O, Tauchi H, Kawaishi K, et al. Expression of the vascular endothelial growth factor (VEGF) receptor gene, KDR, in hematopoietic cells and inhibitory effect of VEGF on apoptotic cell death caused by ionizing radiation. Cancer Res 1995; 55: 5687-92
-
(1995)
Cancer Res
, vol.55
, pp. 5687-5692
-
-
Katoh, O.1
Tauchi, H.2
Kawaishi, K.3
-
90
-
-
0032549799
-
Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor
-
90. Soker S, Takahima S, Mia HQ, et al. Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor. Cell 1998; 735-45
-
(1998)
Cell
, pp. 735-745
-
-
Soker, S.1
Takahima, S.2
Mia, H.Q.3
-
91
-
-
0029846376
-
Regulalion of vascular endothelial growth factor expression in human colon carcinoma cells by cell density
-
91. Koura AN, Liu W, Kitadai Y, et al. Regulalion of vascular endothelial growth factor expression in human colon carcinoma cells by cell density. Cancer Res 1996; 56: 3891-4
-
(1996)
Cancer Res
, vol.56
, pp. 3891-3894
-
-
Koura, A.N.1
Liu, W.2
Kitadai, Y.3
-
92
-
-
0028986075
-
Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation
-
92. Brown K, Gerstbergre S, Carlson L, et al. Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation. Science 1995; 267: 1485-8
-
(1995)
Science
, vol.267
, pp. 1485-1488
-
-
Brown, K.1
Gerstbergre, S.2
Carlson, L.3
-
93
-
-
0031008750
-
The 230 kDa mature form of KDR/Flk-1 (VEGF receptor-2) activates the PLCγ pathway and partially induces mitotic signals in NIH3T3 fibroblasts
-
93. Takahashi T, Shibuya M. The 230 kDa mature form of KDR/Flk-1 (VEGF receptor-2) activates the PLCγ pathway and partially induces mitotic signals in NIH3T3 fibroblasts. Oncogene 1997; 14: 2079-89
-
(1997)
Oncogene
, vol.14
, pp. 2079-2089
-
-
Takahashi, T.1
Shibuya, M.2
-
94
-
-
0027104066
-
Vascular permeability factor (vascular endothelial growth factor) gene is expressed differentially in normal tissues, macrophages, and tumors
-
94. Berse B, Brown LF, Van De Water L, et al. Vascular permeability factor (vascular endothelial growth factor) gene is expressed differentially in normal tissues, macrophages, and tumors. Mol Biol Cell 1992; 3: 211-20
-
(1992)
Mol Biol Cell
, vol.3
, pp. 211-220
-
-
Berse, B.1
Brown, L.F.2
De Van Water, L.3
-
95
-
-
4243431702
-
Expression of TIE-2 receptor and ligand in human cell lines and tumor biopsy specimens
-
95. Dhingra K, Horn S, Sahin A, et al. Expression of TIE-2 receptor and ligand in human cell lines and tumor biopsy specimens [abstract]. Proc Annu Meet Am Assoc Cancer Res 1997; 38: A3260
-
(1997)
Proc Annu Meet Am Assoc Cancer Res
, vol.38
-
-
Dhingra, K.1
Horn, S.2
Sahin, A.3
-
96
-
-
0030793369
-
Expression of transforming growth factor β type II receptor reduces tumorigenicity in human gastric cancer cells
-
96. Chang J, Park K, Bang YJ, et al. Expression of transforming growth factor β type II receptor reduces tumorigenicity in human gastric cancer cells. Cancer Res 1997; 57: 2856-9
-
(1997)
Cancer Res
, vol.57
, pp. 2856-2859
-
-
Chang, J.1
Park, K.2
Bang, Y.J.3
-
97
-
-
0029066689
-
Inactivation of the type II TGF-β receptor in colon cancer cells with microsatellite instability
-
97. Markowitz S, Wang J, Myeroff L, et al. Inactivation of the type II TGF-β receptor in colon cancer cells with microsatellite instability. Science 1995; 268: 1336-8
-
(1995)
Science
, vol.268
, pp. 1336-1338
-
-
Markowitz, S.1
Wang, J.2
Myeroff, L.3
-
98
-
-
85035177110
-
Loss of receptors for transforming growth factor β receptors: Role in physiology and disease
-
98. Kadin M, Cavaille-Coll MW, Gertz R, et al. Loss of receptors for transforming growth factor β receptors: role in physiology and disease. J Biomed Sci 1996; 3: 143-58
-
(1996)
J Biomed Sci
, vol.3
, pp. 143-158
-
-
Kadin, M.1
Cavaille-Coll, M.W.2
Gertz, R.3
-
99
-
-
0030048263
-
Genetic change in transforming growth factor β (TGF-β) receptor type I gene correlates with insensitivity to RGF-β1 in human prostate cancer cells
-
99. Kim IY, Ahn HJ, Zelner DJ, et al. Genetic change in transforming growth factor β (TGF-β) receptor type I gene correlates with insensitivity to RGF-β1 in human prostate cancer cells. Cancer Res 1996; 56: 44-8
-
(1996)
Cancer Res
, vol.56
, pp. 44-48
-
-
Kim, I.Y.1
Ahn, H.J.2
Zelner, D.J.3
-
100
-
-
0028785603
-
Microsatellite instability and mutations of the transforming growth factor β type II receptor gene in colorectal cancer
-
100. Parsons R, Myerhoff LL, Liu BL, et al. Microsatellite instability and mutations of the transforming growth factor β type II receptor gene in colorectal cancer. Cancer Res 1995; 55: 5548-50
-
(1995)
Cancer Res
, vol.55
, pp. 5548-5550
-
-
Parsons, R.1
Myerhoff, L.L.2
Liu, B.L.3
-
101
-
-
0028785602
-
A transforming growth factor β receptor type II gene mutation common in colon and gastric but rare in endomietric cancers with microsatellite instability
-
101. Myeroff LL, Parsons R, Kim SJ, et al. A transforming growth factor β receptor type II gene mutation common in colon and gastric but rare in endomietric cancers with microsatellite instability. Cancer Res 1995; 55: 5545-7
-
(1995)
Cancer Res
, vol.55
, pp. 5545-5547
-
-
Myeroff, L.L.1
Parsons, R.2
Kim, S.J.3
-
102
-
-
0027377915
-
Novel and known protein tyrosine kinases and their abnormal expression in human melanoma
-
102. Easty DJ, Ganz SE, Farr CJ, et al. Novel and known protein tyrosine kinases and their abnormal expression in human melanoma. J Invest Dermatol 1993; 101: 679-84
-
(1993)
J Invest Dermatol
, vol.101
, pp. 679-684
-
-
Easty, D.J.1
Ganz, S.E.2
Farr, C.J.3
-
103
-
-
0026687329
-
Isolation and characterization of a novel receptor-type protein tyrosine kinase (hek) from a human pre-B cell lines
-
103. Boyd AW, Ward LD, Wicks IP, et al. Isolation and characterization of a novel receptor-type protein tyrosine kinase (hek) from a human pre-B cell lines. J Biol Chem 1992; 267: 3262-7
-
(1992)
J Biol Chem
, vol.267
, pp. 3262-3267
-
-
Boyd, A.W.1
Ward, L.D.2
Wicks, I.P.3
-
104
-
-
0026500682
-
Molecular cloning of HEK the gene encoding a receptor tyrosine kinase expressed by human lymphoid tumor cell lines
-
104. Wicks IP, Wilkinson D, Salvaris E, et al. Molecular cloning of HEK the gene encoding a receptor tyrosine kinase expressed by human lymphoid tumor cell lines. Proc Natl Acad Sci U S A 1992; 89: 1611-5
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 1611-1615
-
-
Wicks, I.P.1
Wilkinson, D.2
Salvaris, E.3
-
105
-
-
0029005355
-
Protein B61 as a new growth factor: Expression of B61 and up-regulation of its receptor epithelial cell kinase during melanoma progression
-
105. Easty DJ, Guthrie BA, Maung K, et al. Protein B61 as a new growth factor: expression of B61 and up-regulation of its receptor epithelial cell kinase during melanoma progression. Cancer Res 1995; 55: 2528-32
-
(1995)
Cancer Res
, vol.55
, pp. 2528-2532
-
-
Easty, D.J.1
Guthrie, B.A.2
Maung, K.3
-
106
-
-
0023741167
-
Evolution, expression and chromosomal location of a novel receptor tyrosine kinase gene
-
106. Maru Y, Hirai H, Yoshida MC, et al. Evolution, expression and chromosomal location of a novel receptor tyrosine kinase gene. Mol Cell Biol 1988; 8: 3770-6
-
(1988)
Mol Cell Biol
, vol.8
, pp. 3770-3776
-
-
Maru, Y.1
Hirai, H.2
Yoshida, M.C.3
-
107
-
-
0028985898
-
Point mutation of the RET proto-oncogene in the TT human medullary thyroid carcinoma cell line
-
107. Carlomagno F, Savatore D, Santoro M, et al. Point mutation of the RET proto-oncogene in the TT human medullary thyroid carcinoma cell line. Biochem Biophys Res Commun 1995; 207: 1022-8
-
(1995)
Biochem Biophys Res Commun
, vol.207
, pp. 1022-1028
-
-
Carlomagno, F.1
Savatore, D.2
Santoro, M.3
-
108
-
-
0029821103
-
ret/PTC-1, -2, and -3 oncogene rearrangements in human thyroid carcinomas: Implications for metastatic potential?
-
108. Sugg SL, Zheng L, Rosen IB, et al. ret/PTC-1, -2, and -3 oncogene rearrangements in human thyroid carcinomas: implications for metastatic potential? J Clin Endocrin Metab 1996; 81: 3360-5
-
(1996)
J Clin Endocrin Metab
, vol.81
, pp. 3360-3365
-
-
Sugg, S.L.1
Zheng, L.2
Rosen, I.B.3
-
109
-
-
0029851837
-
Expression of the RET proto-oncogene in normal human tissues, pheochromocytomas, and other tumors of neural crest origin
-
109. Takaya K, Yoshimasa T, Arai H, et al. Expression of the RET proto-oncogene in normal human tissues, pheochromocytomas, and other tumors of neural crest origin. J Mol Med 1996; 74: 617-21
-
(1996)
J Mol Med
, vol.74
, pp. 617-621
-
-
Takaya, K.1
Yoshimasa, T.2
Arai, H.3
-
110
-
-
0028227510
-
Expression of the ret proto-oncogene product in human normal and neoplastic tissues of neural crest origin
-
110. Nakamura T, Ishizaka Y, Nagao M, et al. Expression of the ret proto-oncogene product in human normal and neoplastic tissues of neural crest origin. J Pathol 1994; 172: 255-60
-
(1994)
J Pathol
, vol.172
, pp. 255-260
-
-
Nakamura, T.1
Ishizaka, Y.2
Nagao, M.3
-
111
-
-
4243327388
-
Expression of alternatively spliced RET transcripts in the developing human kidney and Wilm's tumor
-
111. Ivanchuk S, Eng C, Myers S, et al. Expression of alternatively spliced RET transcripts in the developing human kidney and Wilm's tumor. Am J Hum Genet 1995; 57: A302
-
(1995)
Am J Hum Genet
, vol.57
-
-
Ivanchuk, S.1
Eng, C.2
Myers, S.3
-
112
-
-
0026022153
-
Expression of platelet-derived growth factors, transforming growth factors, and the ros gene in a variety of primary human brain tumors
-
112. Mapstone T, McMichael M, Goldthwait D. Expression of platelet-derived growth factors, transforming growth factors, and the ros gene in a variety of primary human brain tumors. Neurosurgery 1991; 28: 216-22
-
(1991)
Neurosurgery
, vol.28
, pp. 216-222
-
-
Mapstone, T.1
McMichael, M.2
Goldthwait, D.3
-
113
-
-
0028199077
-
Analysis of oncogene expression in primary human gliomas: Evidence for increased expression of the ros oncogene
-
113. Watkins D, Dion F, Poisson M, et al. Analysis of oncogene expression in primary human gliomas: evidence for increased expression of the ros oncogene. Cancer Genet Cytogenet 1994; 72: 130-6
-
(1994)
Cancer Genet Cytogenet
, vol.72
, pp. 130-136
-
-
Watkins, D.1
Dion, F.2
Poisson, M.3
-
114
-
-
0025353292
-
Differential expression of ros oncogene in primary human astrocytomas and astrocytoma cell lines
-
114. Wu JK, Chikaraishi DM, Differential expression of ros oncogene in primary human astrocytomas and astrocytoma cell lines. Cancer Res 1990; 50: 3032-5
-
(1990)
Cancer Res
, vol.50
, pp. 3032-3035
-
-
Wu, J.K.1
Chikaraishi, D.M.2
-
116
-
-
0028176880
-
Transforming growth factor-α and endocrine sensitivity in breast cancer
-
116. Nicholson RI, McClelland RA, Gee JMW, et al. Transforming growth factor-α and endocrine sensitivity in breast cancer. Cancer Res 1994; 54: 1684-9
-
(1994)
Cancer Res
, vol.54
, pp. 1684-1689
-
-
Nicholson, R.I.1
McClelland, R.A.2
Gee, J.M.W.3
-
117
-
-
0025228724
-
Transcripts for transforming growth factors in human breast cancer: Clinical correlates
-
117. Barrett-Lee P, Travers M, Luqmani Y, et al. Transcripts for transforming growth factors in human breast cancer: clinical correlates. Br J Cancer 1990; 61: 612-7
-
(1990)
Br J Cancer
, vol.61
, pp. 612-617
-
-
Barrett-Lee, P.1
Travers, M.2
Luqmani, Y.3
-
118
-
-
0025505265
-
Epidermal growth factor: Receptor and ligand expression in human breast cancer
-
118. Murphy LC, Dotslaw H, Wong MSJ. Epidermal growth factor: receptor and ligand expression in human breast cancer. Semin Cancer Biol 1990; 1: 305-15
-
(1990)
Semin Cancer Biol
, vol.1
, pp. 305-315
-
-
Murphy, L.C.1
Dotslaw, H.2
Wong, M.S.J.3
-
119
-
-
0027254405
-
The prognostic significance of transforming growth factors in human breast cancer
-
119. Murray PA, Barrett-Lee P, Travers M, et al. The prognostic significance of transforming growth factors in human breast cancer. Br J Cancer 1993; 67: 1408-12
-
(1993)
Br J Cancer
, vol.67
, pp. 1408-1412
-
-
Murray, P.A.1
Barrett-Lee, P.2
Travers, M.3
-
120
-
-
0010066582
-
A v-erbB-related protooncogene, c-erbB-2, is distinct from the c-erbB-1/epidermal growth factor-receptor gene and is amplified in a human salivary gland adenocarcinoma
-
120. Semba K, Kamata N, Toyoshima K, et al. A v-erbB-related protooncogene, c-erbB-2, is distinct from the c-erbB-1/epidermal growth factor-receptor gene and is amplified in a human salivary gland adenocarcinoma. Proc Natl Acad Sci U S A 1985; 82: 6497-501
-
(1985)
Proc Natl Acad Sci U S A
, vol.82
, pp. 6497-6501
-
-
Semba, K.1
Kamata, N.2
Toyoshima, K.3
-
122
-
-
0028176477
-
4: A role for receptor heterodimerization in growth signalling
-
4: a role for receptor heterodimerization in growth signalling. Cell 1994; 78: 5-8
-
(1994)
Cell
, vol.78
, pp. 5-8
-
-
Carraway, K.L.1
Cantley, L.C.2
-
123
-
-
0025690737
-
Heterodimerization of the erbB-1 and erbB-2 receptors in human breast carcinoma cells: A mechanism for receptor transregulation
-
123. Goldman R, Levy RB, Peles E, et al. Heterodimerization of the erbB-1 and erbB-2 receptors in human breast carcinoma cells: a mechanism for receptor transregulation. Biochemistry 1990; 29: 11024-8
-
(1990)
Biochemistry
, vol.29
, pp. 11024-11028
-
-
Goldman, R.1
Levy, R.B.2
Peles, E.3
-
124
-
-
0026609680
-
p185c-neu and epidermal growth factor receptor associate into a structure composed of activated kinases
-
124. Qian X, Decker SJ, Greene MI. p185c-neu and epidermal growth factor receptor associate into a structure composed of activated kinases. Proc Natl Acad Sci U S A 1992; 89: 1330-4
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 1330-1334
-
-
Qian, X.1
Decker, S.J.2
Greene, M.I.3
-
125
-
-
0028302018
-
3 is involved in activating phosphatidylinositol 3-kinase by epidermal growth factor
-
3 is involved in activating phosphatidylinositol 3-kinase by epidermal growth factor. Mol Cell Biol 1994; 14: 3550-8
-
(1994)
Mol Cell Biol
, vol.14
, pp. 3550-3558
-
-
Soltoff, S.P.1
Carraway, K.L.2
Prigent, S.A.3
-
126
-
-
0024375271
-
Purification and cDNA cloning of a receptor for basic fibroblast growth factor
-
126. Lee PL, Johnson DE, Cousens LS, et al. Purification and cDNA cloning of a receptor for basic fibroblast growth factor. Science 1989; 245: 57-60
-
(1989)
Science
, vol.245
, pp. 57-60
-
-
Lee, P.L.1
Johnson, D.E.2
Cousens, L.S.3
-
127
-
-
0023691808
-
Novel tyrosine kinase identified by phosphotyrosine antibody screening of cDN libraries
-
127. Kornbluth S, Paulson DE, Hanafusa H. Novel tyrosine kinase identified by phosphotyrosine antibody screening of cDN libraries. Mol Cell Biol 1988; 8: 5541-4
-
(1988)
Mol Cell Biol
, vol.8
, pp. 5541-5544
-
-
Kornbluth, S.1
Paulson, D.E.2
Hanafusa, H.3
-
128
-
-
0026020296
-
Isolation of an additional member of the fibroblast growth factor receptor family FGFR-3
-
128. Keegan K, Johnson DE, Williams LT, et al. Isolation of an additional member of the fibroblast growth factor receptor family FGFR-3. Proc Natl Acad Sci U S A 1991; 88: 1095-9
-
(1991)
Proc Natl Acad Sci U S A
, vol.88
, pp. 1095-1099
-
-
Keegan, K.1
Johnson, D.E.2
Williams, L.T.3
-
129
-
-
0025778586
-
FGFR-4,, a novel acidic fibroblast growth factor receptor with a distinct expression pattern
-
129. Partanan J, Makla TP, Eerola E, et al. FGFR-4,, a novel acidic fibroblast growth factor receptor with a distinct expression pattern. EMBO J 1991; 10: 1347-54
-
(1991)
EMBO J
, vol.10
, pp. 1347-1354
-
-
Partanan, J.1
Makla, T.P.2
Eerola, E.3
-
130
-
-
0025896043
-
Flg-2, a new member of the family of fibroblast growth factor receptors
-
130. Avivi A, Zimmer Y, Yayon A, et al. Flg-2, a new member of the family of fibroblast growth factor receptors. Oncogene 1991; 6: 1089-92
-
(1991)
Oncogene
, vol.6
, pp. 1089-1092
-
-
Avivi, A.1
Zimmer, Y.2
Yayon, A.3
-
131
-
-
0027053785
-
Heparin-binding keratinocyte growth factor is a candidate stromal-to-epithelial cell andromedin
-
131. Yan G, Fukabori Y, Nikolaropoulos S, et al. Heparin-binding keratinocyte growth factor is a candidate stromal-to-epithelial cell andromedin. Mol Endocrinol 1992; 6: 2123-8
-
(1992)
Mol Endocrinol
, vol.6
, pp. 2123-2128
-
-
Yan, G.1
Fukabori, Y.2
Nikolaropoulos, S.3
-
132
-
-
0027198248
-
Exon switching and activation of stromal and embryonic fibroblast growth factor (FGF): FGF receptor genes in prostate epithelial cells accompany stromal independence and malignancy
-
132. Yan G, Fukabori Y, McBride G, et al. Exon switching and activation of stromal and embryonic fibroblast growth factor (FGF): FGF receptor genes in prostate epithelial cells accompany stromal independence and malignancy. Mol Cell Biol 1993; 13: 4513-22
-
(1993)
Mol Cell Biol
, vol.13
, pp. 4513-4522
-
-
Yan, G.1
Fukabori, Y.2
McBride, G.3
-
133
-
-
0025953395
-
Distribution of vascular permeability factor (vascular endothelial growth factor) in tumors: Concentration in tumor blood vessels
-
133. Dvorak HF, Sioussat TM, Brown LF, et al. Distribution of vascular permeability factor (vascular endothelial growth factor) in tumors: concentration in tumor blood vessels. J Exp Med 1991; 174: 1275-8
-
(1991)
J Exp Med
, vol.174
, pp. 1275-1278
-
-
Dvorak, H.F.1
Sioussat, T.M.2
Brown, L.F.3
-
134
-
-
0026446102
-
Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo
-
134. Plate KH, Breier G, Weich HA et al. Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo. Nature 1992; 359: 845-8
-
(1992)
Nature
, vol.359
, pp. 845-848
-
-
Plate, K.H.1
Breier, G.2
Weich, H.A.3
-
135
-
-
0025464639
-
Platelet-derived growth factor: Mechanism of action and possible in vivo function
-
135. Heldin CH, Westermark B. Platelet-derived growth factor: mechanism of action and possible in vivo function. Cell Regul 1990; 1: 555-66
-
(1990)
Cell Regul
, vol.1
, pp. 555-566
-
-
Heldin, C.H.1
Westermark, B.2
-
136
-
-
0023916425
-
Expression of recombinant platelet-derived growth factor A- and B-chain homodimers in Rat-1 cells and human fibroblasts reveals differences in protein processing and autocrine effects
-
136. Bywater M, Rorsman F, Bongcam-Rudloff E, et al. Expression of recombinant platelet-derived growth factor A- and B-chain homodimers in Rat-1 cells and human fibroblasts reveals differences in protein processing and autocrine effects. Mol Cell Biol 1988; 8: 2753-62
-
(1988)
Mol Cell Biol
, vol.8
, pp. 2753-2762
-
-
Bywater, M.1
Rorsman, F.2
Bongcam-Rudloff, E.3
-
137
-
-
0023848656
-
Autocrine stimulation of intracellular PDGF receptors in v-sis transformed cells
-
137. Keating MT, Williams LT. Autocrine stimulation of intracellular PDGF receptors in v-sis transformed cells. Science 1988; 239: 914-6
-
(1988)
Science
, vol.239
, pp. 914-916
-
-
Keating, M.T.1
Williams, L.T.2
-
138
-
-
0024242552
-
Rapid turnover of the platelet-derived growth factor receptor in sis-transformed cells and reversal by suramin: Implications for the mechanism of autocrine transformation
-
138. Huang SS, Huang JS. Rapid turnover of the platelet-derived growth factor receptor in sis-transformed cells and reversal by suramin: implications for the mechanism of autocrine transformation. J Biol Chem 1988; 263: 12608-18
-
(1988)
J Biol Chem
, vol.263
, pp. 12608-12618
-
-
Huang, S.S.1
Huang, J.S.2
-
139
-
-
0025940119
-
Platelet-derived growth factor in autocrine transformation
-
139. Westermark B, Heldin CH. Platelet-derived growth factor in autocrine transformation. Cancer Res 51: 5087-92
-
Cancer Res
, vol.51
, pp. 5087-5092
-
-
Westermark, B.1
Heldin, C.H.2
-
140
-
-
0028280287
-
Epithelial-stromal interactions in basal cell cancer: The PDGF system
-
140. Ponten F, Ren Z, Nister M, et al. Epithelial-stromal interactions in basal cell cancer: the PDGF system. J Invest Dermatol 1994; 102: 304-9
-
(1994)
J Invest Dermatol
, vol.102
, pp. 304-309
-
-
Ponten, F.1
Ren, Z.2
Nister, M.3
-
141
-
-
0025019999
-
Expression of platelet-derived growth factor beta-receptors on stromal tissue cells in human carcinoid tumors
-
141. Funa K, Papanicolaou V, Juhlin C, et al. Expression of platelet-derived growth factor beta-receptors on stromal tissue cells in human carcinoid tumors. Cancer Res 1990; 50: 748-53
-
(1990)
Cancer Res
, vol.50
, pp. 748-753
-
-
Funa, K.1
Papanicolaou, V.2
Juhlin, C.3
-
142
-
-
0026516380
-
Expression of platelet-derived growth factor and its receptors in neuroendocrine tumors of the digestive system
-
142. Chaudhry A, Panpanicolaou V, Oberg K, et al. Expression of platelet-derived growth factor and its receptors in neuroendocrine tumors of the digestive system. Cancer Res 1992; 52: 1006-12
-
(1992)
Cancer Res
, vol.52
, pp. 1006-1012
-
-
Chaudhry, A.1
Panpanicolaou, V.2
Oberg, K.3
-
143
-
-
0025609216
-
Actions of TNF and IFN-gamma on angiogenesis in vitro
-
143. Sato N, Nariuchi H, Tsuruoka N, et al. Actions of TNF and IFN-gamma on angiogenesis in vitro. J Invest Dermatol 1990; 95: 85S-89S
-
(1990)
J Invest Dermatol
, vol.95
-
-
Sato, N.1
Nariuchi, H.2
Tsuruoka, N.3
-
144
-
-
0008887031
-
Endothelial cell hyperplasia in human glioblastoma: Co-expression of mRNA for platelet-derived growth factor (PDGF) B chain and PDGF receptor suggests autocrine growth stimulation
-
144. Hermansson M, Nister M, Betsholtz C, et al. Endothelial cell hyperplasia in human glioblastoma: co-expression of mRNA for platelet-derived growth factor (PDGF) B chain and PDGF receptor suggests autocrine growth stimulation. Proc Natl Acad Sci U S A 1988; 85: 7748-52
-
(1988)
Proc Natl Acad Sci U S A
, vol.85
, pp. 7748-7752
-
-
Hermansson, M.1
Nister, M.2
Betsholtz, C.3
-
145
-
-
0026022620
-
Human microvascular endothelial cells express receptors for platelet-derived growth factor
-
145. Beitz JG, Kim IS, Calabrese P, et al. Human microvascular endothelial cells express receptors for platelet-derived growth factor. Proc Natl Acad Sci U S A 1991; 88: 2021-5
-
(1991)
Proc Natl Acad Sci U S A
, vol.88
, pp. 2021-2025
-
-
Beitz, J.G.1
Kim, I.S.2
Calabrese, P.3
-
146
-
-
0025259592
-
Nucleotide sequences and expression of a novel human receptor-type tyrosine kinase gene (flt) closely related to the fms family
-
146. Shibuya M, Yamguchi S, Yamane A, et al. Nucleotide sequences and expression of a novel human receptor-type tyrosine kinase gene (flt) closely related to the fms family. Oncogene 1990; 5: 519-24
-
(1990)
Oncogene
, vol.5
, pp. 519-524
-
-
Shibuya, M.1
Yamguchi, S.2
Yamane, A.3
-
147
-
-
0026572345
-
The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor
-
147. DeVries C, Escobedo JA, Ueono H, et al. The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor. Science 1992; 255: 989-91
-
(1992)
Science
, vol.255
, pp. 989-991
-
-
DeVries, C.1
Escobedo, J.A.2
Ueono, H.3
-
148
-
-
0026702970
-
Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor
-
148. Terman BI, Dougher-Vermazen M, Carrion ME, et al. Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor. Biochem Biophys Res Commun 1992; 187: 1579-86
-
(1992)
Biochem Biophys Res Commun
, vol.187
, pp. 1579-1586
-
-
Terman, B.I.1
Dougher-Vermazen, M.2
Carrion, M.E.3
-
149
-
-
0027466849
-
High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis
-
149. Millauer B, Wizigmann-Voos S, Schnurch H, et al. High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis. Cell 1993; 72: 835-46
-
(1993)
Cell
, vol.72
, pp. 835-846
-
-
Millauer, B.1
Wizigmann-Voos, S.2
Schnurch, H.3
-
150
-
-
0030026897
-
A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases
-
published errata appears in EMBO J 1996; 15: 1751
-
150. Joukov V, Pajusola K, Kaipainen A, et al. A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases [published errata appears in EMBO J 1996; 15: 1751]. EMBO J 1996; 15: 290-8
-
(1996)
EMBO J
, vol.15
, pp. 290-298
-
-
Joukov, V.1
Pajusola, K.2
Kaipainen, A.3
-
151
-
-
0027997863
-
Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factor
-
151. Waltenberger J, Claesson-Welsh L, Siegbahn A, et al. Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factor. J Biol Chem 1994; 269: 26988-95
-
(1994)
J Biol Chem
, vol.269
, pp. 26988-26995
-
-
Waltenberger, J.1
Claesson-Welsh, L.2
Siegbahn, A.3
-
152
-
-
0029945524
-
Differential endothelial migration and proliferation to basic fibroblast growth factor and vascular endothelial growth factor
-
152. Yoshida A, Anand-Apte B, Zetter BR. Differential endothelial migration and proliferation to basic fibroblast growth factor and vascular endothelial growth factor. Growth Factors 1996; 13: 57-64
-
(1996)
Growth Factors
, vol.13
, pp. 57-64
-
-
Yoshida, A.1
Anand-Apte, B.2
Zetter, B.R.3
-
153
-
-
0031039243
-
The biology of vascular endothelial growth factor
-
153. Ferrara N, Davis-Smith T. The biology of vascular endothelial growth factor. Endocr Rev 1997; 18: 4-25
-
(1997)
Endocr Rev
, vol.18
, pp. 4-25
-
-
Ferrara, N.1
Davis-Smith, T.2
-
154
-
-
0027424647
-
Vascular endothelial growth factor expression during embryogenesis and tissue repair suggests a role in endothelial differentiation and blood vessel growth
-
154. Peters KG, DeVries C, Williams LT. Vascular endothelial growth factor expression during embryogenesis and tissue repair suggests a role in endothelial differentiation and blood vessel growth. Proc Natl Acad Sci U S A 1993, 90: 8915-9
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 8915-8919
-
-
Peters, K.G.1
DeVries, C.2
Williams, L.T.3
-
155
-
-
0029021660
-
Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium
-
155. Fong GH, Rossant J, Gertsenstein M, et al. Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium. Nature 1995; 376: 66-70
-
(1995)
Nature
, vol.376
, pp. 66-70
-
-
Fong, G.H.1
Rossant, J.2
Gertsenstein, M.3
-
156
-
-
0028899424
-
Vascular endothelial cells growth factor promotes tyrosine phosphorylation of mediators of signal transduclion that contain SH2 domains: Association with endothelial cell proliferation
-
156. Guo D, Jia Q, Song HY, et al. Vascular endothelial cells growth factor promotes tyrosine phosphorylation of mediators of signal transduclion that contain SH2 domains: association with endothelial cell proliferation. J Biol Chem 1995; 270: 6729-33
-
(1995)
J Biol Chem
, vol.270
, pp. 6729-6733
-
-
Guo, D.1
Jia, Q.2
Song, H.Y.3
-
157
-
-
0031466232
-
The vascular endothelial growth factor receptor KDR activates multiple signal transduction pathways in porcine aortic endothelial cells
-
157. Kroll J, Waltenberger J. The vascular endothelial growth factor receptor KDR activates multiple signal transduction pathways in porcine aortic endothelial cells. J Biol Chem 1997; 272: 32521-7
-
(1997)
J Biol Chem
, vol.272
, pp. 32521-32527
-
-
Kroll, J.1
Waltenberger, J.2
-
159
-
-
0032495978
-
Tyrosine 1213 of Flt-1 is a major binding site of Nck and SHP-2
-
159. Igarashi K, Isohara T, Kato T, et al. Tyrosine 1213 of Flt-1 is a major binding site of Nck and SHP-2. Biochem Biophys Res Commun 1998; 246: 95-9
-
(1998)
Biochem Biophys Res Commun
, vol.246
, pp. 95-99
-
-
Igarashi, K.1
Isohara, T.2
Kato, T.3
-
160
-
-
0032521212
-
Vascular permeability factor/vascular endothelial growth factor-mediated signaling in mouse mesentery vascular endothelium
-
160. Mukhopadhyay D, Nagy JA, Manseau EJ, et al. Vascular permeability factor/vascular endothelial growth factor-mediated signaling in mouse mesentery vascular endothelium. Cancer Res 1998; 58: 1278-84
-
(1998)
Cancer Res
, vol.58
, pp. 1278-1284
-
-
Mukhopadhyay, D.1
Nagy, J.A.2
Manseau, E.J.3
-
161
-
-
0025688912
-
Vascular permeability factor: A tumor-derived polypeptide that induces endothelial cell and monocyte procoagulant activity, and promotes monocyte migration
-
161. Clauss M, Gerlach M, Brett J, et al. Vascular permeability factor: a tumor-derived polypeptide that induces endothelial cell and monocyte procoagulant activity, and promotes monocyte migration. J Exp Med 1990; 172: 1535-45
-
(1990)
J Exp Med
, vol.172
, pp. 1535-1545
-
-
Clauss, M.1
Gerlach, M.2
Brett, J.3
-
162
-
-
0029166407
-
Angiogenic factors stimulate mast-cell migration
-
162. Gruber BL, Marchese MJ, Kew R. Angiogenic factors stimulate mast-cell migration. Blood 1995; 86: 2488-93
-
(1995)
Blood
, vol.86
, pp. 2488-2493
-
-
Gruber, B.L.1
Marchese, M.J.2
Kew, R.3
-
163
-
-
0029867554
-
Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1
-
163. Barleon B, Sozzani S, Zhou D, et al. Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1. Blood 1996; 87 3336-43
-
(1996)
Blood
, vol.87
, pp. 3336-3343
-
-
Barleon, B.1
Sozzani, S.2
Zhou, D.3
-
164
-
-
0028798083
-
A unique signal transduction from FlT tyrosine kinase, a receptor for vascular endothelial growth factor VEGF
-
164. Seetharam L, Gotoh N, Maru Y, et al. A unique signal transduction from FlT tyrosine kinase, a receptor for vascular endothelial growth factor VEGF. Oncogene 1995; 10: 135-47
-
(1995)
Oncogene
, vol.10
, pp. 135-147
-
-
Seetharam, L.1
Gotoh, N.2
Maru, Y.3
-
165
-
-
0024801035
-
Vascular permeability factor, an endothelial cell mitogen related to PDGF
-
165. Keck PJ, Hauser SD, Krivi G, et al. Vascular permeability factor, an endothelial cell mitogen related to PDGF. Science 1989; 246: 1309-12
-
(1989)
Science
, vol.246
, pp. 1309-1312
-
-
Keck, P.J.1
Hauser, S.D.2
Krivi, G.3
-
166
-
-
0024818355
-
Vascular endothelial growth factor is a secreted angiogenic mitogen
-
166. Leung DL, Cachianes G, Kuang WJ, et al. Vascular endothelial growth factor is a secreted angiogenic mitogen. Science 1996; 246: 1306-9
-
(1996)
Science
, vol.246
, pp. 1306-1309
-
-
Leung, D.L.1
Cachianes, G.2
Kuang, W.J.3
-
167
-
-
0024816246
-
Isolation and characterization of newly identified endothelial cell mitogen produced by AtT-20 cells
-
167. Plouet J, Schilling J, Gospodarowicz D. Isolation and characterization of newly identified endothelial cell mitogen produced by AtT-20 cells. EMBO J 1989; 8: 3801-6
-
(1989)
EMBO J
, vol.8
, pp. 3801-3806
-
-
Plouet, J.1
Schilling, J.2
Gospodarowicz, D.3
-
168
-
-
0028237788
-
Vasculotropin/vascular endothelial growth factor induces differentiation in cultured osteoblasts
-
168. Midy V, Plouet J. Vasculotropin/vascular endothelial growth factor induces differentiation in cultured osteoblasts. Biochem Biophys Res Commun 1994; 199: 380-6
-
(1994)
Biochem Biophys Res Commun
, vol.199
, pp. 380-386
-
-
Midy, V.1
Plouet, J.2
-
169
-
-
0022800838
-
Insulin-like growth factor 1 receptor primary structure: Comparison with insulin receptor suggests structural determinants that define functional specificity
-
169. Ullrich A, Gray A, Tam AW, et al. Insulin-like growth factor 1 receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity. EMBO J 1986; 5: 2503-12
-
(1986)
EMBO J
, vol.5
, pp. 2503-2512
-
-
Ullrich, A.1
Gray, A.2
Tam, A.W.3
-
170
-
-
0001828896
-
The insulin-like growth factor receptor: Molecular biology, heterogeneity and regulation
-
LeRoith D, editor. Boca Raton (FL): CRC Press
-
170. Werner H, Woloschak M, Stannard B, et al. The insulin-like growth factor receptor: molecular biology, heterogeneity and regulation. In: LeRoith D, editor. Insulin-like growth factors: molecular and cellular aspects. Boca Raton (FL): CRC Press, 1991: 17-47
-
(1991)
Insulin-like Growth Factors: Molecular and Cellular Aspects
, pp. 17-47
-
-
Werner, H.1
Woloschak, M.2
Stannard, B.3
-
171
-
-
0002415707
-
Biological actions of the insulin-like growth factors
-
Le Roith D, editor. Boca Raton (FL): CRC Press
-
171. Lowe WL. Biological actions of the insulin-like growth factors. In: Le Roith D, editor. Insulin-like growth factors: molecular and cellular aspects. Boca Raton (FL): CRC Press, 1991: 49-85
-
(1991)
Insulin-like Growth Factors: Molecular and Cellular Aspects
, pp. 49-85
-
-
Lowe, W.L.1
-
172
-
-
0027094144
-
Formation of haematopoietic microenvironment and haematopoietic stem cells from single human bone marrow stem cells
-
172. Huang S, Terstappen LWMM. Formation of haematopoietic microenvironment and haematopoietic stem cells from single human bone marrow stem cells. Nature 1992; 360: 745-9
-
(1992)
Nature
, vol.360
, pp. 745-749
-
-
Huang, S.1
Terstappen, L.W.M.M.2
-
174
-
-
0028244050
-
Two alternatively spliced forms of the human insulin-like growth factor 1 receptor have distinct biological activities and internalization kinetics
-
174. Condorelli G, Bueno R, Smith RJ. Two alternatively spliced forms of the human insulin-like growth factor 1 receptor have distinct biological activities and internalization kinetics. J Biol Chem 1994; 269: 8510-6
-
(1994)
J Biol Chem
, vol.269
, pp. 8510-8516
-
-
Condorelli, G.1
Bueno, R.2
Smith, R.J.3
-
175
-
-
0023927948
-
Insulin-like growth factor I receptors on mouse neuroblastoma cells: Two beta subunits are derived from differences in glycosylation
-
175. Ota A, Wilson GL, Le Roith D. Insulin-like growth factor I receptors on mouse neuroblastoma cells: two beta subunits are derived from differences in glycosylation. Eur J Biochem 1988; 174: 521-30
-
(1988)
Eur J Biochem
, vol.174
, pp. 521-530
-
-
Ota, A.1
Wilson, G.L.2
Le Roith, D.3
-
176
-
-
0027170056
-
Mutational analysis of insulin receptor function: Consensus and controversy
-
176. Tavare JM, Siddle K. Mutational analysis of insulin receptor function: consensus and controversy. Biochim Biophys Acta 1993; 1178: 21-39
-
(1993)
Biochim Biophys Acta
, vol.1178
, pp. 21-39
-
-
Tavare, J.M.1
Siddle, K.2
-
177
-
-
0028275037
-
Hybrid and atypical insulin/insulin-like growth factor I receptors
-
177. Siddle K, Soos, MA, Field CE, et al. Hybrid and atypical insulin/insulin-like growth factor I receptors. Hormone Res 1994; 41: 56-65
-
(1994)
Hormone Res
, vol.41
, pp. 56-65
-
-
Siddle, K.1
Soos, M.A.2
Field, C.E.3
-
178
-
-
0025813375
-
The structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein
-
178. Sun XJ, Rothenberg P, Kahn CR, et al. The structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein. Nature 1991; 352: 73-7
-
(1991)
Nature
, vol.352
, pp. 73-77
-
-
Sun, X.J.1
Rothenberg, P.2
Kahn, C.R.3
-
179
-
-
0026595373
-
The expression and function of IRS-1 in insulin signal transmission
-
179. Sun XJ, Miralpeix M, Myers MG, et al. The expression and function of IRS-1 in insulin signal transmission. J Biol Chem 1992; 267: 22662-72
-
(1992)
J Biol Chem
, vol.267
, pp. 22662-22672
-
-
Sun, X.J.1
Miralpeix, M.2
Myers, M.G.3
-
180
-
-
0027512244
-
The insulin and insulin-like growth factor-1 receptor substrate IRS-1 associates with and activates phosphatidylinositol 3-kinase in vitro
-
180. Giorgetti S, Ballotti R, Kowalski-Chauvel A, et al. The insulin and insulin-like growth factor-1 receptor substrate IRS-1 associates with and activates phosphatidylinositol 3-kinase in vitro. J Biol Chem 1993; 268: 7358-64
-
(1993)
J Biol Chem
, vol.268
, pp. 7358-7364
-
-
Giorgetti, S.1
Ballotti, R.2
Kowalski-Chauvel, A.3
-
181
-
-
0028036724
-
Insulin receptor substrate-1 (IRS1) and she compete for a limited pool of Grb2 in mediating insulin downstream signalling
-
181. Yamauchi K, Pessin JE. Insulin receptor substrate-1 (IRS1) and She compete for a limited pool of Grb2 in mediating insulin downstream signalling. J Biol Chem 1994; 269: 31107-14
-
(1994)
J Biol Chem
, vol.269
, pp. 31107-31114
-
-
Yamauchi, K.1
Pessin, J.E.2
-
182
-
-
0028242350
-
Evidence for a functional role of She proteins in mitogenic signalling induced by insulin, insulin-like growth factor-1, and epidermal growth factor
-
182. Sasaoka T, Rose DW, Jhun BH, et al. Evidence for a functional role of She proteins in mitogenic signalling induced by insulin, insulin-like growth factor-1, and epidermal growth factor. J Biol Chem 1994; 269: 13689-94
-
(1994)
J Biol Chem
, vol.269
, pp. 13689-13694
-
-
Sasaoka, T.1
Rose, D.W.2
Jhun, B.H.3
-
183
-
-
0028953268
-
Insulin-like growth factor-1 stimulated tyrosine phosphorylation of endogenous c-Crk
-
183. Heitner-Johnson D, LeRoith D. Insulin-like growth factor-1 stimulated tyrosine phosphorylation of endogenous c-Crk. J Biol Chem 1995; 290: 5187-90
-
(1995)
J Biol Chem
, vol.290
, pp. 5187-5190
-
-
Heitner-Johnson, D.1
Leroith, D.2
-
184
-
-
0028122971
-
CRK protein binds to two guanine nucleotide-releasing proteins for the Ras family and modulates nerve growth factor-induced activation of Ras in PC12 cells
-
184. Matsuda M, Hshimoti Y, Muroya K, et al. CRK protein binds to two guanine nucleotide-releasing proteins for the Ras family and modulates nerve growth factor-induced activation of Ras in PC12 cells. Mol Cel Biol 1994; 14: 5495-500
-
(1994)
Mol Cel Biol
, vol.14
, pp. 5495-5500
-
-
Matsuda, M.1
Hshimoti, Y.2
Muroya, K.3
-
185
-
-
0002590420
-
Somatomedin: Physiological control and effects on cell proliferation
-
Baserga R, editor. Berlin: Springer-Verlag KG
-
185. Clemmons DR, Van Wyk JJ. Somatomedin: physiological control and effects on cell proliferation. In: Baserga R, editor. Tissue growth factors. Berlin: Springer-Verlag KG, 1981; 161
-
(1981)
Tissue Growth Factors
, pp. 161
-
-
Clemmons, D.R.1
Van Wyk, J.J.2
-
186
-
-
0020539695
-
Variables controlling somatomedin production by cultured human fibroblasts
-
186. Clemmons DR, Shaw DS. Variables controlling somatomedin production by cultured human fibroblasts. J Cell Physiol 1983; 115: 137-42
-
(1983)
J Cell Physiol
, vol.115
, pp. 137-142
-
-
Clemmons, D.R.1
Shaw, D.S.2
-
187
-
-
0028157211
-
The role of the IGF-1 receptor in the growth and transformation of mammalian cells
-
187. Baserga R, Sell C, Porcu P, et al. The role of the IGF-1 receptor in the growth and transformation of mammalian cells. Cell Prolif 1994; 27: 63-71
-
(1994)
Cell Prolif
, vol.27
, pp. 63-71
-
-
Baserga, R.1
Sell, C.2
Porcu, P.3
-
188
-
-
0026483202
-
Inhibition of cell proliferation by peptide analogs of IGF-1
-
188. Pietrzkowski Z, Wernicke D, Porcu P, et al. Inhibition of cell proliferation by peptide analogs of IGF-1. Cancer Res 1992; 52: 6447
-
(1992)
Cancer Res
, vol.52
, pp. 6447
-
-
Pietrzkowski, Z.1
Wernicke, D.2
Porcu, P.3
-
189
-
-
0026011107
-
Constitutively expressed c-myb abrogates the requirement for insulin-like growth factor 1 in 3T3 fibroblasts
-
189. Travali S, Reiss K, Ferber A, et al. Constitutively expressed c-myb abrogates the requirement for insulin-like growth factor 1 in 3T3 fibroblasts. Mol Cell Biol 1991; 11: 731-6
-
(1991)
Mol Cell Biol
, vol.11
, pp. 731-736
-
-
Travali, S.1
Reiss, K.2
Ferber, A.3
-
190
-
-
0026336492
-
The proto-oncogene c-myb increases the expression of insulin-like growth factor 1 and insulin-like growth factor 1 receptor messenger RNAs by a transcriptional mechanism
-
190. Reiss K, Ferger A, Travali S, et al. The proto-oncogene c-myb increases the expression of insulin-like growth factor 1 and insulin-like growth factor 1 receptor messenger RNAs by a transcriptional mechanism. Cancer Res 1991; 51: 5997-6000
-
(1991)
Cancer Res
, vol.51
, pp. 5997-6000
-
-
Reiss, K.1
Ferger, A.2
Travali, S.3
-
191
-
-
0026842293
-
Constitutive expression of insulin-like growth factor 1 and insulin-like growth 1 receptor abrogates all requirements for exogenous growth factors
-
191. Pietrzkowski Z, Lammers, R, Carpenter G, et al. Constitutive expression of insulin-like growth factor 1 and insulin-like growth 1 receptor abrogates all requirements for exogenous growth factors. Cell Growth Differ 1992; 3: 199-205
-
(1992)
Cell Growth Differ
, vol.3
, pp. 199-205
-
-
Pietrzkowski, Z.1
Lammers, R.2
Carpenter, G.3
-
192
-
-
0026744027
-
The growth-stimulatory effect of Simian virus 40 T antigen requires the interaction of insulin-like growth factor 1 with its receptor
-
192. Porcu P, Ferber A, Pietrzkowski Z, et al. The growth-stimulatory effect of Simian virus 40 T antigen requires the interaction of insulin-like growth factor 1 with its receptor. Mol Cell Biol 1992; 12: 5069-77
-
(1992)
Mol Cell Biol
, vol.12
, pp. 5069-5077
-
-
Porcu, P.1
Ferber, A.2
Pietrzkowski, Z.3
-
193
-
-
0026447761
-
The insulin-like growth factor 1 receptor is required for the proliferation of hematopoietic cells
-
193. Reiss K, Porcu P, Sell C, et al. The insulin-like growth factor 1 receptor is required for the proliferation of hematopoietic cells. Oncogene 1992; 7: 2243-8
-
(1992)
Oncogene
, vol.7
, pp. 2243-2248
-
-
Reiss, K.1
Porcu, P.2
Sell, C.3
-
194
-
-
0028271497
-
Rat glioblastoma cells expressing an antisense RNA to the insulin-like growth factor-1 (IGF-I) receptor are non-tumorigenic and induce of wild type tumors
-
194. Resnicoff M, Sell C, Rubini M, et al. Rat glioblastoma cells expressing an antisense RNA to the insulin-like growth factor-1 (IGF-I) receptor are non-tumorigenic and induce of wild type tumors. Cancer Res 1994; 54: 2218-22
-
(1994)
Cancer Res
, vol.54
, pp. 2218-2222
-
-
Resnicoff, M.1
Sell, C.2
Rubini, M.3
-
195
-
-
0027407639
-
Inhibition of growth of prostatic cancer cell lines by peptide analogs of IGF-1
-
195. Pietrzkowski Z, Mulholland G, Gomella L, et al. Inhibition of growth of prostatic cancer cell lines by peptide analogs of IGF-1. Cancer Res 1993; 53: 1102-6
-
(1993)
Cancer Res
, vol.53
, pp. 1102-1106
-
-
Pietrzkowski, Z.1
Mulholland, G.2
Gomella, L.3
-
196
-
-
0027366338
-
Simian virus 40 large tumor antigen is unable to transform mouse embryonic fibroblasts lacking type-I IGF receptor
-
196. Sell C, Rubini M, Rubin R, et al. Simian virus 40 large tumor antigen is unable to transform mouse embryonic fibroblasts lacking type-I IGF receptor. Proc Natl Acad Sci U S A 1993; 90: 11217-21
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 11217-11221
-
-
Sell, C.1
Rubini, M.2
Rubin, R.3
-
197
-
-
0028157211
-
The role of the IGF-1 receptor in the growth and transformation of mammalian cells
-
197. Baserga R, Sell C, Porcu P, et al. The role of the IGF-1 receptor in the growth and transformation of mammalian cells. Cell Prolif 1994; 27: 63-71
-
(1994)
Cell Prolif
, vol.27
, pp. 63-71
-
-
Baserga, R.1
Sell, C.2
Porcu, P.3
-
198
-
-
0026010993
-
Hepatocyte growth factor/hepatopoietin A stimulates the growth of rat kidney proximal tubule epithelial cells (RPTE), rat nonparenchymal liver cells, human melanoma cells, mouse keratinocytes and stimulates anchorage-independent growth of SV40-transformed RPTE
-
198. Kan M, Zhang G, Zarnegar R, et al. Hepatocyte growth factor/hepatopoietin A stimulates the growth of rat kidney proximal tubule epithelial cells (RPTE), rat nonparenchymal liver cells, human melanoma cells, mouse keratinocytes and stimulates anchorage-independent growth of SV40-transformed RPTE. Biochem Biophys Res Commun 1991; 174: 331-7
-
(1991)
Biochem Biophys Res Commun
, vol.174
, pp. 331-337
-
-
Kan, M.1
Zhang, G.2
Zarnegar, R.3
-
199
-
-
0023661693
-
Scatter factor is a fibroblast-derived modulator of epithelial cell mobility
-
199. Stoker M, Gherardi E, Perryman M, et al. Scatter factor is a fibroblast-derived modulator of epithelial cell mobility. Nature 1987; 327: 239-342
-
(1987)
Nature
, vol.327
, pp. 239-342
-
-
Stoker, M.1
Gherardi, E.2
Perryman, M.3
-
200
-
-
0026722243
-
Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth
-
200. Bussolino F, Di Renzo MF, Ziche M, et al. Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth. J Cell Biol 1992; 119: 629-41
-
(1992)
J Cell Biol
, vol.119
, pp. 629-641
-
-
Bussolino, F.1
Di Renzo, M.F.2
Ziche, M.3
-
202
-
-
0025119463
-
Scatter factor: Molecular characteristics and effect on the invasiveness of epithelial cells
-
202. Weidner KM, Behrens J, Vanderkerckhone J, et al. Scatter factor: molecular characteristics and effect on the invasiveness of epithelial cells. J Cell Biol 1990; 111: 2907-11
-
(1990)
J Cell Biol
, vol.111
, pp. 2907-2911
-
-
Weidner, K.M.1
Behrens, J.2
Vanderkerckhone, J.3
-
203
-
-
0027342344
-
Molecular characteristics of HGF/SF and its role in cell motility and invasion
-
203. Weidner KM, Hartmann G, Naldini L, et al. Molecular characteristics of HGF/SF and its role in cell motility and invasion. EXS 1993; 65: 311-28
-
(1993)
EXS
, vol.65
, pp. 311-328
-
-
Weidner, K.M.1
Hartmann, G.2
Naldini, L.3
-
204
-
-
0024523622
-
Tyrosine kinase receptor indistinguishable from the c-met protein
-
204. Giordano S, Ponzetto D, Di Renzo MF, et al. Tyrosine kinase receptor indistinguishable from the c-met protein. Nature 2989; 339: 155-6
-
Nature
, vol.339
, pp. 155-156
-
-
Giordano, S.1
Ponzetto, D.2
Di Renzo, M.F.3
-
205
-
-
0023674310
-
Characterization of the TPR-MET oncogene p65 and the MET protooncogene p140 protein tyrosine kinases
-
205. Gonzatti-Haces M, Seth A, Park M, et al. Characterization of the TPR-MET oncogene p65 and the MET protooncogene p140 protein tyrosine kinases. Proc Natl Acad Sci U S A 1988; 85: 21-5
-
(1988)
Proc Natl Acad Sci U S A
, vol.85
, pp. 21-25
-
-
Gonzatti-Haces, M.1
Seth, A.2
Park, M.3
-
206
-
-
0025932538
-
C-terminal truncated forms of Met, the hepatocyte growth factor receptor
-
206. Prat M, Crepaldi T, Gandino L, et al. C-terminal truncated forms of Met, the hepatocyte growth factor receptor. Mol Cell Biol 1991; 11: 5954-60
-
(1991)
Mol Cell Biol
, vol.11
, pp. 5954-5960
-
-
Prat, M.1
Crepaldi, T.2
Gandino, L.3
-
207
-
-
0028040132
-
Generation of a truncated hepatocyte growth factor receptor in the endoplasmic reticulum
-
207. Crepaldi T, Prat M, Giordano S, et al. Generation of a truncated hepatocyte growth factor receptor in the endoplasmic reticulum. J Biol Chem 1994; 269: 1750-5
-
(1994)
J Biol Chem
, vol.269
, pp. 1750-1755
-
-
Crepaldi, T.1
Prat, M.2
Giordano, S.3
-
208
-
-
0013659710
-
HGFR
-
Hardie G, Hanks S, editors. New York: Academic Press
-
208. Cooper CS. HGFR. In: Hardie G, Hanks S, editors. The protein kinase facts book. New York: Academic Press, 1995: 218-20
-
(1995)
The Protein Kinase Facts Book
, pp. 218-220
-
-
Cooper, C.S.1
-
209
-
-
0027300619
-
The when and how of Src regulation
-
209. Cooper JA, Howell B. The when and how of Src regulation. Cell 1993; 73: 1051-4
-
(1993)
Cell
, vol.73
, pp. 1051-1054
-
-
Cooper, J.A.1
Howell, B.2
-
211
-
-
0026537831
-
Expression cloning of the TGF-β type II receptor a functional transmembrane serine/threonine kinase
-
211. Lin H, Wang XF, Ng-Eaton E, et al. Expression cloning of the TGF-β type II receptor a functional transmembrane serine/threonine kinase. Cell 1992; 68: 775-85
-
(1992)
Cell
, vol.68
, pp. 775-785
-
-
Lin, H.1
Wang, X.F.2
Ng-Eaton, E.3
-
212
-
-
0026496172
-
TGF-β signals through a heteromeric protein kinase receptor complex
-
212. Wrana JL, Attisano L, Carcamo J, et al. TGF-β signals through a heteromeric protein kinase receptor complex. Cell 1992; 71: 1003-14
-
(1992)
Cell
, vol.71
, pp. 1003-1014
-
-
Wrana, J.L.1
Attisano, L.2
Carcamo, J.3
-
213
-
-
0029063595
-
Transforming growth factor β: A cytokine with multiple actions in oncology and potential clinical applications
-
213. Kekow J, Wiedemann GJ. Transforming growth factor β: a cytokine with multiple actions in oncology and potential clinical applications [review]. Int J Oncol 1995; 7: 177-82
-
(1995)
Int J Oncol
, vol.7
, pp. 177-182
-
-
Kekow, J.1
Wiedemann, G.J.2
-
214
-
-
0031438047
-
TGFβ-signalling from cell membrane to nucleus through SMAD proteins
-
214. Heldin CH, Miyazono K, ten Dijke P. TGFβ-signalling from cell membrane to nucleus through SMAD proteins. Nature 1997; 390: 465-71
-
(1997)
Nature
, vol.390
, pp. 465-471
-
-
Heldin, C.H.1
Miyazono, K.2
Ten Dijke, P.3
-
215
-
-
0027930903
-
Formation of heterooligomeric complexes of type I and type II receptors for transforming growth factor-β
-
215. Yamashita H, ten Dijke P, Franzen P, et al. Formation of heterooligomeric complexes of type I and type II receptors for transforming growth factor-β. J Biol Chem 1994; 269: 20172-8
-
(1994)
J Biol Chem
, vol.269
, pp. 20172-20178
-
-
Yamashita, H.1
Ten Dijke, P.2
Franzen, P.3
-
216
-
-
0030613262
-
Phosphorylation of Ser465 and Ser467 in the C-terminus of Smad2 mediates interaction with Smad4 and is required for TGF-β signalling
-
216. Souchelnytskyi S, Tamaki K, Engstom U, et al. Phosphorylation of Ser465 and Ser467 in the C-terminus of Smad2 mediates interaction with Smad4 and is required for TGF-β signalling. J Biol Chem 1997; 272: 28107-15
-
(1997)
J Biol Chem
, vol.272
, pp. 28107-28115
-
-
Souchelnytskyi, S.1
Tamaki, K.2
Engstom, U.3
-
217
-
-
0030611757
-
Identification of Smad7, a TGFβ-inducible antagonist of TGF-β signalling
-
217. Nakao A, Afrakhte M, Moren A, et al. Identification of Smad7, a TGFβ-inducible antagonist of TGF-β signalling. Nature 1997; 389: 631-5
-
(1997)
Nature
, vol.389
, pp. 631-635
-
-
Nakao, A.1
Afrakhte, M.2
Moren, A.3
-
218
-
-
0030765945
-
Smad6 inhibits signalling by the TGF-β superfamily
-
218. Imamura T, Takase M, Nishihara A, et al. Smad6 inhibits signalling by the TGF-β superfamily. Nature 1997; 389: 622-6
-
(1997)
Nature
, vol.389
, pp. 622-626
-
-
Imamura, T.1
Takase, M.2
Nishihara, A.3
-
219
-
-
0031561324
-
Signal transduction: Feedback from inhibitory SMADs
-
219. Whitman M. Signal transduction: feedback from inhibitory SMADs. Nature 1997; 389: 549-51
-
(1997)
Nature
, vol.389
, pp. 549-551
-
-
Whitman, M.1
-
220
-
-
0030775491
-
Inactivation of Smad4 in gastric carcinomas
-
220. Powell SM, Harper JC, Hamilton SR, et al. Inactivation of Smad4 in gastric carcinomas. Cancer Res 1997; 57: 4221-4
-
(1997)
Cancer Res
, vol.57
, pp. 4221-4224
-
-
Powell, S.M.1
Harper, J.C.2
Hamilton, S.R.3
-
221
-
-
0030848192
-
Frequency of Smad gene mutations in human cancers
-
221. Riggins GJ, Kinzler KW, Vogelstein B, et al. Frequency of Smad gene mutations in human cancers. Cancer Res 1997; 57: 2578-80
-
(1997)
Cancer Res
, vol.57
, pp. 2578-2580
-
-
Riggins, G.J.1
Kinzler, K.W.2
Vogelstein, B.3
-
222
-
-
0025114866
-
TGF-β induces bimodal proliferation of connective tissue cells via complex control of an autocrine PDGF loop
-
222. Battegay EJ, Raines EW, Seifert RA, et al. TGF-β induces bimodal proliferation of connective tissue cells via complex control of an autocrine PDGF loop. Cell 1990; 63: 515-24
-
(1990)
Cell
, vol.63
, pp. 515-524
-
-
Battegay, E.J.1
Raines, E.W.2
Seifert, R.A.3
-
223
-
-
0028174305
-
Involvement of pp60c-src with two major signaling pathways in human breast cancer
-
223. Luttrell DK, Lee A, Lansing TJ, et al. Involvement of pp60c-src with two major signaling pathways in human breast cancer. Proc Nati Acad Sci U S A 1994; 91: 83-7
-
(1994)
Proc Nati Acad Sci U S A
, vol.91
, pp. 83-87
-
-
Luttrell, D.K.1
Lee, A.2
Lansing, T.J.3
-
224
-
-
0029121267
-
Potentiation of epidermal growth factor receptor-mediated oncogenesis by c-Src: Implications for the etiology of multiple human cancers
-
224. Maa MC, Leu TH, McCarley DJ, et al. Potentiation of epidermal growth factor receptor-mediated oncogenesis by c-Src: Implications for the etiology of multiple human cancers. Proc Natl Acad Sci U S A 1995; 92: 6981-5
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 6981-6985
-
-
Maa, M.C.1
Leu, T.H.2
McCarley, D.J.3
-
225
-
-
0024478058
-
pp60c-src tyrosine kinase, myristylation, and modulatory domains are required for enhanced mitogenic responsiveness to epidermal growth factor seen in cells overexpressing c-src
-
225. Wilson LK, Luttrell DK, Parsons JT, et al. pp60c-src tyrosine kinase, myristylation, and modulatory domains are required for enhanced mitogenic responsiveness to epidermal growth factor seen in cells overexpressing c-src. Mol Cell Biol 1989; 9: 1536-44
-
(1989)
Mol Cell Biol
, vol.9
, pp. 1536-1544
-
-
Wilson, L.K.1
Luttrell, D.K.2
Parsons, J.T.3
-
226
-
-
0027267532
-
Nonreceptor tyrosine protein kinases
-
226. Bolen JB. Nonreceptor tyrosine protein kinases. Oncogene 1993; 8: 2025-31
-
(1993)
Oncogene
, vol.8
, pp. 2025-2031
-
-
Bolen, J.B.1
-
227
-
-
0027339924
-
Increased levels of p21ras-GTP and enhanced DNA synthesis accompany elevated tyrosyl phosphorylation of GAP-associated proteins, p190 and p62, in c-src overexpressors
-
227. Chang JH, Wilson LK, Moyers JS, et al. Increased levels of p21ras-GTP and enhanced DNA synthesis accompany elevated tyrosyl phosphorylation of GAP-associated proteins, p190 and p62, in c-src overexpressors. Oncogene 1993; 8: 959-67
-
(1993)
Oncogene
, vol.8
, pp. 959-967
-
-
Chang, J.H.1
Wilson, L.K.2
Moyers, J.S.3
-
228
-
-
0026460102
-
Identification and characterization of a cytoskeleton-associated, epidermal growth factor sensitive pp60c-src substrate
-
228. Maa MC, Wilson LK, Moyers JS, et al. Identification and characterization of a cytoskeleton-associated, epidermal growth factor sensitive pp60c-src substrate. Oncogene 1992; 7: 2429-38
-
(1992)
Oncogene
, vol.7
, pp. 2429-2438
-
-
Maa, M.C.1
Wilson, L.K.2
Moyers, J.S.3
-
230
-
-
0032498231
-
LAT: The ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation
-
230. Zhang W, Sloan-Lancaster J, Kitchen J, et al. LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation. Cell 1998; 92: 83-92
-
(1998)
Cell
, vol.92
, pp. 83-92
-
-
Zhang, W.1
Sloan-Lancaster, J.2
Kitchen, J.3
-
232
-
-
0026674221
-
Characterization of protein tyrosine kinases from human breast cancer: Involvement of the c-src oncogene product
-
232. Ottenholf-Kaliff AE, Rijksen G, van Beurden EA, et al. Characterization of protein tyrosine kinases from human breast cancer: involvement of the c-src oncogene product. Cancer Res 1992; 52: 4773-8
-
(1992)
Cancer Res
, vol.52
, pp. 4773-4778
-
-
Ottenholf-Kaliff, A.E.1
Rijksen, G.2
Van Beurden, E.A.3
-
233
-
-
0022930029
-
Analysis of pp60c-src protein kinase activity in human tumor cell lines and tissues
-
233. Rosen N, Bolen JB, Schwartz AM, et al. Analysis of pp60c-src protein kinase activity in human tumor cell lines and tissues. J Biol Chem 1986; 261: 13754-9
-
(1986)
J Biol Chem
, vol.261
, pp. 13754-13759
-
-
Rosen, N.1
Bolen, J.B.2
Schwartz, A.M.3
-
234
-
-
0028910667
-
Src activity increases and yes activity decreases during mitosis of human colon carcinoma cells
-
234. Park J, Cartwright CA. Src activity increases and Yes activity decreases during mitosis of human colon carcinoma cells. Mol Cell Biol 1995; 15: 2374-82
-
(1995)
Mol Cell Biol
, vol.15
, pp. 2374-2382
-
-
Park, J.1
Cartwright, C.A.2
-
235
-
-
0027170840
-
c-Yes tyrosine kinase activity in human colon carcinoma
-
235. Park J, Meisler AI, Cartwright CA. c-Yes tyrosine kinase activity in human colon carcinoma. Oncogene 1993; 8: 2627-35
-
(1993)
Oncogene
, vol.8
, pp. 2627-2635
-
-
Park, J.1
Meisler, A.I.2
Cartwright, C.A.3
-
236
-
-
0029781431
-
Differential activation of pp60c-src and pp62c-yes in human colorectal carcinoma liver metastases
-
236. Han NM, Curley SA, Gallick GE. Differential activation of pp60c-src and pp62c-yes in human colorectal carcinoma liver metastases. Clin Cancer Res 1996; 2: 1397-404
-
(1996)
Clin Cancer Res
, vol.2
, pp. 1397-1404
-
-
Han, N.M.1
Curley, S.A.2
Gallick, G.E.3
-
237
-
-
0026021970
-
Expression of the c-fgr and hck protein-tyrosine kinases in acute myeloid leukemic blasts is associated with early commitment and differentiation events in the monocytic and granulocytic lineages
-
237. Willman CL, Stewart CC, Longacre TL, et al. Expression of the c-fgr and hck protein-tyrosine kinases in acute myeloid leukemic blasts is associated with early commitment and differentiation events in the monocytic and granulocytic lineages. Blood 1991; 77: 726-34
-
(1991)
Blood
, vol.77
, pp. 726-734
-
-
Willman, C.L.1
Stewart, C.C.2
Longacre, T.L.3
-
238
-
-
0025923783
-
Differential expression of p62c-yes in normal, hyperplastic and neoplastic human epidermis
-
238. Krueger J, Zhao YH, Murphy D, et al. Differential expression of p62c-yes in normal, hyperplastic and neoplastic human epidermis. Oncogene 1991; 6: 933-40
-
(1991)
Oncogene
, vol.6
, pp. 933-940
-
-
Krueger, J.1
Zhao, Y.H.2
Murphy, D.3
-
239
-
-
0022403402
-
Amplification of c-yes-I protooncogene in a primary human gastric cancer
-
239. Seki T, Fujii G, Mori S, et al. Amplification of c-yes-I protooncogene in a primary human gastric cancer. Jpn J Cancer Res 1985; 76: 907-10
-
(1985)
Jpn J Cancer Res
, vol.76
, pp. 907-910
-
-
Seki, T.1
Fujii, G.2
Mori, S.3
-
240
-
-
0026410640
-
Human chronic lymphocytic leukemia cells regularly express mRNAs of the protooncogenes lck and c-fgr
-
240. Abts H, Juecker M, Diehl V, et al. Human chronic lymphocytic leukemia cells regularly express mRNAs of the protooncogenes lck and c-fgr. Leuk Res 1991; 15: 987-97
-
(1991)
Leuk Res
, vol.15
, pp. 987-997
-
-
Abts, H.1
Juecker, M.2
Diehl, V.3
-
241
-
-
4244206082
-
The expression of the P56-LCK proto-oncogene in B-cell lineage neoplasias
-
241. von Knethen A, Abts H, Kube D, et al. The expression of the P56-LCK proto-oncogene in B-cell lineage neoplasias. Ann Hematol 1993; 67: A66
-
(1993)
Ann Hematol
, vol.67
-
-
Von Knethen, A.1
Abts, H.2
Kube, D.3
-
242
-
-
0027447595
-
Selective increase of alternatively spliced Lck transcripts from the proximal promoter in hematopoietic malignancies
-
242. Rouer E, Dreyfus F, Melle J, et al. Selective increase of alternatively spliced Lck transcripts from the proximal promoter in hematopoietic malignancies. Leukemia 1993; 7: 246-50
-
(1993)
Leukemia
, vol.7
, pp. 246-250
-
-
Rouer, E.1
Dreyfus, F.2
Melle, J.3
-
243
-
-
0025852638
-
Over-expression of lck in Burkitt's lymphoma cell lines
-
243. Juecker M, Abts H, Eick D, et al. Over-expression of lck in Burkitt's lymphoma cell lines [letter]. Leukemia 1991; 5: 528-30
-
(1991)
Leukemia
, vol.5
, pp. 528-530
-
-
Juecker, M.1
Abts, H.2
Eick, D.3
-
244
-
-
0026321201
-
The LCK gene is involved in the t(1;7)(p34;q34) in the T cell acute lymphoblastic leukemia derived cell line, HSB-2
-
244. Burnett RC, David JC, Harden AM, et al. The LCK gene is involved in the t(1;7)(p34;q34) in the T cell acute lymphoblastic leukemia derived cell line, HSB-2. Genes, Chromosomes Cancer 1991; 3: 461-7
-
(1991)
Genes, Chromosomes Cancer
, vol.3
, pp. 461-467
-
-
Burnett, R.C.1
David, J.C.2
Harden, A.M.3
-
245
-
-
0023911241
-
Expression of the human T-cell-specific tyrosine kinase YT16 (lck) message in leukemic T-cell lines
-
245. Koga Y, Kimura N, Minowada J, et al. Expression of the human T-cell-specific tyrosine kinase YT16 (lck) message in leukemic T-cell lines. Cancer Res 1988; 48: 856-9
-
(1988)
Cancer Res
, vol.48
, pp. 856-859
-
-
Koga, Y.1
Kimura, N.2
Minowada, J.3
-
246
-
-
0030018278
-
Augmented expression of LCK message directed from the downstream promoter in human colorectal cancer specimens
-
246. Nakamura K, Chijiiwa Y, Nawata H. Augmented expression of LCK message directed from the downstream promoter in human colorectal cancer specimens. Eur J Cancer 1996; 32A: 1401-7
-
(1996)
Eur J Cancer
, vol.32 A
, pp. 1401-1407
-
-
Nakamura, K.1
Chijiiwa, Y.2
Nawata, H.3
-
247
-
-
0029766159
-
Expression of alternatively spliced lck transcripts from the proximal promoter in colorectal cancer derived cell lines
-
247. Mayer K, Ballhausen WG. Expression of alternatively spliced lck transcripts from the proximal promoter in colorectal cancer derived cell lines. Anticancer Res 1996; 16: 1733-7
-
(1996)
Anticancer Res
, vol.16
, pp. 1733-1737
-
-
Mayer, K.1
Ballhausen, W.G.2
-
248
-
-
0023598108
-
Expression of the lck tyrosine kinase gene in human colon carcinoma and other non-lymphoid human tumor cell lines
-
248. Veilette A, Foss FM, Sausville EA, et al. Expression of the lck tyrosine kinase gene in human colon carcinoma and other non-lymphoid human tumor cell lines. Oncogene Res 1987; 1: 357-74
-
(1987)
Oncogene Res
, vol.1
, pp. 357-374
-
-
Veilette, A.1
Foss, F.M.2
Sausville, E.A.3
-
249
-
-
0031444615
-
An alternative pathway of expression of p56-lck from type I promoter transcripts in colon carcinoma
-
249. McCracken S, Kim CS, Xu Y, et al. An alternative pathway of expression of p56-lck from type I promoter transcripts in colon carcinoma. Oncogene 1997; 15: 2929-37
-
(1997)
Oncogene
, vol.15
, pp. 2929-2937
-
-
McCracken, S.1
Kim, C.S.2
Xu, Y.3
-
250
-
-
0024472811
-
Alterations in the expression of pp60(c-src) an p56(lck) associated with butyrate-induced differentiation of human colon carcinoma cells
-
250. Foss FM, Veillette A, Sartor O, et al. Alterations in the expression of pp60(c-src) an p56(lck) associated with butyrate-induced differentiation of human colon carcinoma cells. Oncogen Res 1989; 5: 13-23
-
(1989)
Oncogen Res
, vol.5
, pp. 13-23
-
-
Foss, F.M.1
Veillette, A.2
Sartor, O.3
-
251
-
-
0000286732
-
A minute chromosome in human granulocyte leukemia
-
251. Nowell PC, Hungerford DA. A minute chromosome in human granulocyte leukemia. Science 1960; 132: 1497-500
-
(1960)
Science
, vol.132
, pp. 1497-1500
-
-
Nowell, P.C.1
Hungerford, D.A.2
-
252
-
-
0030583281
-
Association of CD24 with the kinase c-fgr in a small cell lung cancer cell line and with the kinase Iyn in an erythroleukemia cell line
-
252. Zarn JA, Zimmermann SM, Pass MK, et al. Association of CD24 with the kinase c-fgr in a small cell lung cancer cell line and with the kinase Iyn in an erythroleukemia cell line. Biochem Biophys Res Commun 1996; 225: 384-91
-
(1996)
Biochem Biophys Res Commun
, vol.225
, pp. 384-391
-
-
Zarn, J.A.1
Zimmermann, S.M.2
Pass, M.K.3
-
253
-
-
0024369205
-
Expression of c-fgr in EBV positive and negative B cell tumors
-
253. Tesch H, Abst H, Juecker M, et al. Expression of c-fgr in EBV positive and negative B cell tumors. Leukemia 1989; 3: 897-8
-
(1989)
Leukemia
, vol.3
, pp. 897-898
-
-
Tesch, H.1
Abst, H.2
Juecker, M.3
-
254
-
-
0022580014
-
fgr proto-oncogene mRNA induced in B lymphocytes by Epstein-Barr virus infection
-
254. Cheah MS, Ley TJ, Tronick SR, et al. fgr proto-oncogene mRNA induced in B lymphocytes by Epstein-Barr virus infection. Nature 1986; 319: 238-40
-
(1986)
Nature
, vol.319
, pp. 238-240
-
-
Cheah, M.S.1
Ley, T.J.2
Tronick, S.R.3
-
255
-
-
0027302904
-
Retinoic acid induces changes in c-fgr proto-oncogene mRNA levels in Burkitt's lymphoma cells
-
255. Faulkner L, Katz DR, Brickell PM. Retinoic acid induces changes in c-fgr proto-oncogene mRNA levels in Burkitt's lymphoma cells. Immunobiology 1993; 188: 460-8
-
(1993)
Immunobiology
, vol.188
, pp. 460-468
-
-
Faulkner, L.1
Katz, D.R.2
Brickell, P.M.3
-
256
-
-
0024324713
-
Regulation of c-fgr proto-oncogene expression in Burkitt's lymphoma cells: Effect of interferon treatment and relationship to EBV status and c-myc mRNA levels
-
256. Sharp NA, Luscombe MJ, Clemens MJ. Regulation of c-fgr proto-oncogene expression in Burkitt's lymphoma cells: effect of interferon treatment and relationship to EBV status and c-myc mRNA levels. Oncogene 1989; 4: 1043-6
-
(1989)
Oncogene
, vol.4
, pp. 1043-1046
-
-
Sharp, N.A.1
Luscombe, M.J.2
Clemens, M.J.3
-
257
-
-
0026544414
-
Clinical and histopathologic evaluation of the expression of Ha-ras and fes oncogene products in lung cancer
-
257. Nishio H, Nakamura S, Horai T, et al. Clinical and histopathologic evaluation of the expression of Ha-ras and fes oncogene products in lung cancer. Cancer 1992; 69: 1130-6
-
(1992)
Cancer
, vol.69
, pp. 1130-1136
-
-
Nishio, H.1
Nakamura, S.2
Horai, T.3
-
258
-
-
4243665669
-
Detection of a putative fusion product formed from tumor necrosis factor receptor (TNFR) and the FES/FPS oncogene from probing of two adolescent T-cell ALL substracted cDNA libraries
-
258. Goldman J, Kowalczuk MM, Lafuze JE. Detection of a putative fusion product formed from tumor necrosis factor receptor (TNFR) and the FES/FPS oncogene from probing of two adolescent T-cell ALL substracted cDNA libraries [abstract]. Proc Am Assoc Cancer Res 1994; 35: A3483
-
(1994)
Proc Am Assoc Cancer Res
, vol.35
-
-
Goldman, J.1
Kowalczuk, M.M.2
Lafuze, J.E.3
-
259
-
-
0025080627
-
The human tyrosine kinase gene (FER) maps to chromosome 5 and is deleted in myeloid leukemias with a del(5q)
-
259. Morris C, Heisterkamp N, Hao QL, et al. The human tyrosine kinase gene (FER) maps to chromosome 5 and is deleted in myeloid leukemias with a del(5q). Cytogenics Cell Genet 1990; 53: 196-200
-
(1990)
Cytogenics Cell Genet
, vol.53
, pp. 196-200
-
-
Morris, C.1
Heisterkamp, N.2
Hao, Q.L.3
-
260
-
-
13144276369
-
Proliferation of adult T cell leukemia/lymphoma cells is associated with the constitutive activation of JAK/STAT proteins
-
260. Takemoto S, Mulloy JC, Cereseto A, et al. Proliferation of adult T cell leukemia/lymphoma cells is associated with the constitutive activation of JAK/STAT proteins. Proc Natl Acad Sci U S A 1997; 94: 13897-902
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 13897-13902
-
-
Takemoto, S.1
Mulloy, J.C.2
Cereseto, A.3
-
261
-
-
13344295097
-
Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor
-
261. Meydan N, Grunberger T, Dadi H, et al. Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor. Nature 1996; 379: 645-8
-
(1996)
Nature
, vol.379
, pp. 645-648
-
-
Meydan, N.1
Grunberger, T.2
Dadi, H.3
-
262
-
-
0032488833
-
Midkine induces tumor cell proliferation and binds to a high affinity signaling receptor associated with JAK tyrosine kinases
-
262. Ratovitski EA, Kotzbauer PT, Milbrandt J, et al. Midkine induces tumor cell proliferation and binds to a high affinity signaling receptor associated with JAK tyrosine kinases. J Biol Chem 1998; 273: 3654-60
-
(1998)
J Biol Chem
, vol.273
, pp. 3654-3660
-
-
Ratovitski, E.A.1
Kotzbauer, P.T.2
Milbrandt, J.3
-
263
-
-
0030584699
-
IL-13 induces phosphorylation and activation of Jak2 Janus kinase in human colon carcinoma cell lines: Similarities between IL-4 and IL-12 signaling
-
263. Murata T, Noguchi PD, Puri RK. IL-13 induces phosphorylation and activation of Jak2 Janus kinase in human colon carcinoma cell lines: similarities between IL-4 and IL-12 signaling. J Immunol 1996; 156: 2972-8
-
(1996)
J Immunol
, vol.156
, pp. 2972-2978
-
-
Murata, T.1
Noguchi, P.D.2
Puri, R.K.3
-
264
-
-
4243691952
-
Involvement of focal adhesion kinase (FAK) in endothelial cell retraction during cancer cell invasion
-
264. Okamoto H, Nakamori S, Ohigashi H, et al. Involvement of focal adhesion kinase (FAK) in endothelial cell retraction during cancer cell invasion [abstract]. Proc Annu Meet Am Assoc Cancer Res 1997; 38: A349
-
(1997)
Proc Annu Meet Am Assoc Cancer Res
, vol.38
-
-
Okamoto, H.1
Nakamori, S.2
Ohigashi, H.3
-
265
-
-
4243733896
-
Expression of focal adhesion kinase (FAK) in human astrocytoma cell lines and brain tumors
-
265. Hubbard SL, Dirks P, Murakami M, et al. Expression of focal adhesion kinase (FAK) in human astrocytoma cell lines and brain tumors [abstract]. Proc Annu Meet Am Assoc Cancer Res 1996; 37: A315
-
(1996)
Proc Annu Meet Am Assoc Cancer Res
, vol.37
-
-
Hubbard, S.L.1
Dirks, P.2
Murakami, M.3
-
267
-
-
0029039421
-
Overexpression of the focal adhesion kinase (p125-FAK) in invasive human tumors
-
267. Owens LV, Xu L, Craven RJ, et al. Overexpression of the focal adhesion kinase (p125-FAK) in invasive human tumors. Cancer Res 1995; 55: 2752-5
-
(1995)
Cancer Res
, vol.55
, pp. 2752-2755
-
-
Owens, L.V.1
Xu, L.2
Craven, R.J.3
-
268
-
-
0031112814
-
Overexpression of focal adhesion kinase (P125(FAK)) in human colorectal-carcinoma liver metastases: Independence from c-src or c-yes activation
-
268. Han NM, Fleming RYD, Curley SA, et al. Overexpression of focal adhesion kinase (P125(FAK)) in human colorectal-carcinoma liver metastases: independence from c-src or c-yes activation. Ann Surg Oncol 1997; 4: 264-8
-
(1997)
Ann Surg Oncol
, vol.4
, pp. 264-268
-
-
Han, N.M.1
Fleming, R.Y.D.2
Curley, S.A.3
-
269
-
-
0013635544
-
FAK, a tyrosine kinase implicated in invasion and metastasis, is overexpressed in ovarian carcinoma
-
269. Judson PL, He X, Cance WG, et al. FAK, a tyrosine kinase implicated in invasion and metastasis, is overexpressed in ovarian carcinoma. Gynecol Oncol 1998; 68: 82
-
(1998)
Gynecol Oncol
, vol.68
, pp. 82
-
-
Judson, P.L.1
He, X.2
Cance, W.G.3
-
270
-
-
4244206081
-
Integrin expression on cell adhesion function and up-regulation of P125-FAK and paxillin in metastatic renal carcinoma cells
-
270. Jenq WM, Cooper DR, Ramirez G. Integrin expression on cell adhesion function and up-regulation of P125-FAK and paxillin in metastatic renal carcinoma cells. Mol Biol Cell 1996; 7: 424A
-
(1996)
Mol Biol Cell
, vol.7
-
-
Jenq, W.M.1
Cooper, D.R.2
Ramirez, G.3
-
271
-
-
0029795243
-
Focal adhesion kinase (pp125-FAK) expression, activation and association with paxillin and p50-csk in human metastatic prostate carcinoma
-
271. Tremblay L, Hauck W, Aprikian AG, et al. Focal adhesion kinase (pp125-FAK) expression, activation and association with paxillin and p50-csk in human metastatic prostate carcinoma. Int J Cancer 1996; 68: 164-71
-
(1996)
Int J Cancer
, vol.68
, pp. 164-171
-
-
Tremblay, L.1
Hauck, W.2
Aprikian, A.G.3
-
272
-
-
0029092674
-
Focal adhesion kinase (p125(FAK)) expression correlates with motility of human melanoma cell lines
-
272. Akasaka T, Van Leeuwen RL, Yoshinaga IG, et al. Focal adhesion kinase (p125(FAK)) expression correlates with motility of human melanoma cell lines. J Invest Dermatol 1995; 105: 104-8
-
(1995)
J Invest Dermatol
, vol.105
, pp. 104-108
-
-
Akasaka, T.1
Van Leeuwen, R.L.2
Yoshinaga, I.G.3
-
273
-
-
0030767420
-
Activation of the focal adhesion kinase signal transduction pathway in cervical carcinoma cell lines and human genital epithelial cells immortalized with human papillomavirus type 18
-
273. McCormack SJ, Brazinski SE, Moore JL, et al. Activation of the focal adhesion kinase signal transduction pathway in cervical carcinoma cell lines and human genital epithelial cells immortalized with human papillomavirus type 18. Oncogene 1997; 15: 265-74
-
(1997)
Oncogene
, vol.15
, pp. 265-274
-
-
McCormack, S.J.1
Brazinski, S.E.2
Moore, J.L.3
-
274
-
-
0029094008
-
BCR-ABL; an anti-apoptosis gene in chronic myelogenous leukemia
-
274. Cotter TG. BCR-ABL; an anti-apoptosis gene in chronic myelogenous leukemia. Leuk Lymph 1995; 18: 231-6
-
(1995)
Leuk Lymph
, vol.18
, pp. 231-236
-
-
Cotter, T.G.1
-
275
-
-
0024353722
-
The mouse type IV c-abl gene product is a nuclear protein, and activation of transforming ability is associated with cytoplasmic localization
-
275. Van Etten RA, Jackson P, Baltimore D. The mouse type IV c-abl gene product is a nuclear protein, and activation of transforming ability is associated with cytoplasmic localization. Cell 1989; 58: 669-78
-
(1989)
Cell
, vol.58
, pp. 669-678
-
-
Van Etten, R.A.1
Jackson, P.2
Baltimore, D.3
-
276
-
-
0026551960
-
Cell cycle-regulated binding of c-Abl tyrosine kinase to DNA
-
276. Kipreos ET, Wang JYJ. Cell cycle-regulated binding of c-Abl tyrosine kinase to DNA. Science 1992; 256: 382-5
-
(1992)
Science
, vol.256
, pp. 382-385
-
-
Kipreos, E.T.1
Wang, J.Y.J.2
-
277
-
-
0024343691
-
N-terminal mutations activates the leukemogenic potential of the myristoylated form of c-abl
-
277. Jackson P, Baltimore D. N-terminal mutations activates the leukemogenic potential of the myristoylated form of c-abl. EMBO J 1989; 8: 449-56
-
(1989)
EMBO J
, vol.8
, pp. 449-456
-
-
Jackson, P.1
Baltimore, D.2
-
278
-
-
0025959660
-
BCR first exon sequences specifically activates the BCR/ABL tyrosine kinase oncogene of Philadelphia chromosome positive human leukemias
-
278. Muller AJ, Young JC, Pendergast AM, et al. BCR first exon sequences specifically activates the BCR/ABL tyrosine kinase oncogene of Philadelphia chromosome positive human leukemias. Mol Cell Biol 1991; 11: 1785-92
-
(1991)
Mol Cell Biol
, vol.11
, pp. 1785-1792
-
-
Muller, A.J.1
Young, J.C.2
Pendergast, A.M.3
-
279
-
-
0023571161
-
Nucleotide sequence of testis-derived cDNAs: Implications for testis specific transcription and abl oncogene activation
-
279. Oppi C, Shore SK, Reddy EP. Nucleotide sequence of testis-derived cDNAs: implications for testis specific transcription and abl oncogene activation. Proc Natl Acad Sci U S A 1987; 84: 8200-4
-
(1987)
Proc Natl Acad Sci U S A
, vol.84
, pp. 8200-8204
-
-
Oppi, C.1
Shore, S.K.2
Reddy, E.P.3
-
280
-
-
0028233970
-
The nuclear tyrosine kinase c-Abl negatively regulates cell growth
-
280. Sawyers CL, McLaughlin J, Goga A, et al. The nuclear tyrosine kinase c-Abl negatively regulates cell growth. Cell 1994; 77: 121-31
-
(1994)
Cell
, vol.77
, pp. 121-131
-
-
Sawyers, C.L.1
McLaughlin, J.2
Goga, A.3
-
281
-
-
0029973738
-
Role for c-Abl tyrosine kinase in growth arrest response to DNA damage
-
281. Yuan ZM, Huang Y, Whang Y, et al. Role for c-Abl tyrosine kinase in growth arrest response to DNA damage. Nature 1996; 382: 272-4
-
(1996)
Nature
, vol.382
, pp. 272-274
-
-
Yuan, Z.M.1
Huang, Y.2
Whang, Y.3
-
282
-
-
0028152845
-
In vivo antitumor activity of herbimycin a, a tyrosine kinase inhibitor, targeted against bcr/abl oncoprotein in mice bearing bcr/abl-transfected cells
-
282. Okabe M, Uehara Y, NishimaT, et al. in vivo antitumor activity of herbimycin A, a tyrosine kinase inhibitor, targeted against bcr/abl oncoprotein in mice bearing bcr/abl-transfected cells. Leuk Res 1994; 18: 867-73
-
(1994)
Leuk Res
, vol.18
, pp. 867-873
-
-
Okabe, M.1
Uehara, Y.2
-
283
-
-
0023885305
-
The protein kinase family: Conserved features and deduced phylogeny of the catalytic domains
-
283. Hanks S, Quinn AM, Hunter T. The protein kinase family: conserved features and deduced phylogeny of the catalytic domains. Science 1988; 241: 42-52
-
(1988)
Science
, vol.241
, pp. 42-52
-
-
Hanks, S.1
Quinn, A.M.2
Hunter, T.3
-
284
-
-
0026484261
-
SH2 and SH3 domains: From structure to function
-
284. Pawson T, Gish GD. SH2 and SH3 domains: from structure to function. Cell 1992; 71: 359-62
-
(1992)
Cell
, vol.71
, pp. 359-362
-
-
Pawson, T.1
Gish, G.D.2
-
285
-
-
0028241548
-
Signalling by the cytokine receptor superfamily: JAKs and STATs
-
285. Ihle JN, Witthuhn BA, Quelle FW, et al. Signalling by the cytokine receptor superfamily: JAKs and STATs. Trends Biochem Sci 1994; 19: 222-7
-
(1994)
Trends Biochem Sci
, vol.19
, pp. 222-227
-
-
Ihle, J.N.1
Witthuhn, B.A.2
Quelle, F.W.3
-
286
-
-
0027371337
-
Ras-independent growth factor signalling by transcription factor tyrosine phosphorylation
-
286. Silvennoinen O, Schindler C, Schlessinger J, et al. Ras-independent growth factor signalling by transcription factor tyrosine phosphorylation. Science 1993; 261: 1736-9
-
(1993)
Science
, vol.261
, pp. 1736-1739
-
-
Silvennoinen, O.1
Schindler, C.2
Schlessinger, J.3
-
287
-
-
0027328343
-
The alphas, betas, and kinases of cytokine receptor complexes
-
287. Stahl N, Yancopoulos GD. The alphas, betas, and kinases of cytokine receptor complexes. Cell 1993; 74: 587-90
-
(1993)
Cell
, vol.74
, pp. 587-590
-
-
Stahl, N.1
Yancopoulos, G.D.2
-
288
-
-
0026632288
-
A protein tyrosine kinase in the interferon alpha/beta signalling pathway
-
288. Velazquez L, Fellous M, Stark GR, et al. A protein tyrosine kinase in the interferon alpha/beta signalling pathway. Cell 1992; 70: 313-22
-
(1992)
Cell
, vol.70
, pp. 313-322
-
-
Velazquez, L.1
Fellous, M.2
Stark, G.R.3
-
289
-
-
0027914818
-
Complementation by the protein tyrosine kinase JAK2 of a mutant cell line defective in the interferon-gamma signal transduction pathway
-
289. Watling D, Guschin D, Muller M, et al. Complementation by the protein tyrosine kinase JAK2 of a mutant cell line defective in the interferon-gamma signal transduction pathway. Nature 1993; 366: 166-70
-
(1993)
Nature
, vol.366
, pp. 166-170
-
-
Watling, D.1
Guschin, D.2
Muller, M.3
-
290
-
-
0027494653
-
The protein tyrosine kinase JAK1 complements defects in interferon-alpha/beta and -gamma signal transduction
-
290. Muller M, Briscoe J, Laxton C, et al. The protein tyrosine kinase JAK1 complements defects in interferon-alpha/beta and -gamma signal transduction. Nature 1993; 366: 129-35
-
(1993)
Nature
, vol.366
, pp. 129-135
-
-
Muller, M.1
Briscoe, J.2
Laxton, C.3
-
291
-
-
0027215350
-
Novel protein kinases expressed in human breast cancer
-
291. Cance WG, Craven RJ, Weiner TM, et al. Novel protein kinases expressed in human breast cancer. Int J Cancer 1993; 54: 571-7
-
(1993)
Int J Cancer
, vol.54
, pp. 571-577
-
-
Cance, W.G.1
Craven, R.J.2
Weiner, T.M.3
-
292
-
-
0027993022
-
Functional activation of Jak1 and Jak3 by selective association with IL-2 receptor subunits
-
292. Miyazaki T, Kawahara A, Fujii H, et al. Functional activation of Jak1 and Jak3 by selective association with IL-2 receptor subunits. Science 1994; 266: 1045-7
-
(1994)
Science
, vol.266
, pp. 1045-1047
-
-
Miyazaki, T.1
Kawahara, A.2
Fujii, H.3
-
293
-
-
0032076183
-
Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses
-
293. Rodig S, Meraz MA, White JM, et al. Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses. Cell 1998; 93: 373-83
-
(1998)
Cell
, vol.93
, pp. 373-383
-
-
Rodig, S.1
Meraz, M.A.2
White, J.M.3
-
294
-
-
0032076542
-
Jak2 is essential for signaling through a variety of cytokine receptors
-
294. Parganas E, Wang, D, Stravopodis D, et al. Jak2 is essential for signaling through a variety of cytokine receptors. Cell 1998; 93: 385-95
-
(1998)
Cell
, vol.93
, pp. 385-395
-
-
Parganas, E.1
Wang, D.2
Stravopodis, D.3
-
295
-
-
18244432009
-
Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis
-
295. Neubauer H, Cumao A, Müller M, et al. Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis. Cell 1998; 93: 397-409
-
(1998)
Cell
, vol.93
, pp. 397-409
-
-
Neubauer, H.1
Cumao, A.2
Müller, M.3
-
296
-
-
0027493650
-
A single phosphotyrosine residue of Stat91 required for gene activation by interferon-gamma
-
296. Shuai K, Stark GR, Kerr IM, et al. A single phosphotyrosine residue of Stat91 required for gene activation by interferon-gamma. Science 1993; 261: 1744-6
-
(1993)
Science
, vol.261
, pp. 1744-1746
-
-
Shuai, K.1
Stark, G.R.2
Kerr, I.M.3
-
297
-
-
0029741304
-
STATs find that hanging together can be stimulating
-
297. Leung S, Li X, Stark GR. STATs find that hanging together can be stimulating. Science 1996; 273: 750
-
(1996)
Science
, vol.273
, pp. 750
-
-
Leung, S.1
Li, X.2
Stark, G.R.3
-
298
-
-
0028296179
-
Association of transcription factor APRF and protein kinase Jak1 with the interleukin-6 signal transducer gp130
-
298. Luttieken C, Wegenka UM, Yuan J, et al. Association of transcription factor APRF and protein kinase Jak1 with the interleukin-6 signal transducer gp130. Science 1994; 263: 89-92
-
(1994)
Science
, vol.263
, pp. 89-92
-
-
Luttieken, C.1
Wegenka, U.M.2
Yuan, J.3
-
299
-
-
0027151991
-
Interferon gamma-induced transcription of the high-affinity Fc receptor for IgG requires assembly of a complex that includes the 91-kDa subunit of transcription factor ISGF3
-
299. Pearse RN, Feinman R, Shuai K, et al. Interferon gamma-induced transcription of the high-affinity Fc receptor for IgG requires assembly of a complex that includes the 91-kDa subunit of transcription factor ISGF3. Proc Natl Acad Sci U S A 1993; 90: 4314-8
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 4314-4318
-
-
Pearse, R.N.1
Feinman, R.2
Shuai, K.3
-
300
-
-
0027248709
-
Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction
-
300. Silvennoinen W, Witthuhn BA, Quelle FW, et al. Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction. Proc Natl Acad Sci U S A 1993; 90: 8429-33
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 8429-8433
-
-
Silvennoinen, W.1
Witthuhn, B.A.2
Quelle, F.W.3
-
301
-
-
0027496114
-
A common nuclear signal transduction pathway activated by growth factor and cytokine receptors
-
301. Sadowski HB, Shuai K, Darnell JE, et al. A common nuclear signal transduction pathway activated by growth factor and cytokine receptors. Science 1993; 261: 1739-44
-
(1993)
Science
, vol.261
, pp. 1739-1744
-
-
Sadowski, H.B.1
Shuai, K.2
Darnell, J.E.3
-
302
-
-
0027385186
-
Induction by EGF and interferon-gamma of tyrosine phosphorylated DNA binding proteins in mouse liver nuclei
-
302. Ruff-Jamison S, Chen K, Cohen S. Induction by EGF and interferon-gamma of tyrosine phosphorylated DNA binding proteins in mouse liver nuclei. Science 1993; 261: 1733-6
-
(1993)
Science
, vol.261
, pp. 1733-1736
-
-
Ruff-Jamison, S.1
Chen, K.2
Cohen, S.3
-
303
-
-
0026476697
-
Focal adhesion kinase (p125FAK): A point of convergence in the action of neuropeptides, integrins, and oncogenes
-
303. Zachary I, Rozengurt E. Focal adhesion kinase (p125FAK): a point of convergence in the action of neuropeptides, integrins, and oncogenes. Cell 1992; 71: 891-4
-
(1992)
Cell
, vol.71
, pp. 891-894
-
-
Zachary, I.1
Rozengurt, E.2
-
304
-
-
0028350859
-
Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src
-
304. Schaller MD, Hildebrand JD, Shannon JD, et al. Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src. Mol Cell Biol 1994; 14: 1680-8
-
(1994)
Mol Cell Biol
, vol.14
, pp. 1680-1688
-
-
Schaller, M.D.1
Hildebrand, J.D.2
Shannon, J.D.3
-
305
-
-
0026674919
-
Focal adhesion protein-tyrosine kinase phosphorylated in response to cell attachment to fibronectin
-
305. Hanks SK, Calalb MB, Harper MC, et al. Focal adhesion protein-tyrosine kinase phosphorylated in response to cell attachment to fibronectin. Proc Natl Acad Sci U S A 1992; 89: 8487-91
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 8487-8491
-
-
Hanks, S.K.1
Calalb, M.B.2
Harper, M.C.3
-
306
-
-
0030045610
-
Focal adhesion kinase pp125-FAK is associated with both intercellular junctions and matrix adhesion sites in vivo
-
306. Tani T, Von Koskull H, Virtanan I. Focal adhesion kinase pp125-FAK is associated with both intercellular junctions and matrix adhesion sites in vivo. Histochem Cell Biol 1996; 105: 17-25
-
(1996)
Histochem Cell Biol
, vol.105
, pp. 17-25
-
-
Tani, T.1
Von Koskull, H.2
Virtanan, I.3
-
307
-
-
0030787791
-
Bombesin stimulates the motility of human prostate-carcinoma cells through tyrosine phosphorylation of focal adhesion kinase and of integrin-associated proteins
-
307. Aprikian AG, Tremblay L, Han K, et al. Bombesin stimulates the motility of human prostate-carcinoma cells through tyrosine phosphorylation of focal adhesion kinase and of integrin-associated proteins. Int J Cancer 1997; 72: 498-504
-
(1997)
Int J Cancer
, vol.72
, pp. 498-504
-
-
Aprikian, A.G.1
Tremblay, L.2
Han, K.3
-
308
-
-
0030005414
-
Actin disruption inhibits bombesin stimulation of focal adhesion kinase (pp125-FAK) in prostate carcinoma
-
308. Duncan MD, Harmon JW, Duncan KLK. Actin disruption inhibits bombesin stimulation of focal adhesion kinase (pp125-FAK) in prostate carcinoma. J Surg Res 1996; 63: 359-63
-
(1996)
J Surg Res
, vol.63
, pp. 359-363
-
-
Duncan, M.D.1
Harmon, J.W.2
Duncan, K.L.K.3
-
309
-
-
0028053831
-
Hepatocyte growth factor-scatter factor induces tyrosine phosphorylation of focal adhesion kinase (p125-FAK) and promotes migration and invasion by oral squamous cell carcinoma cells
-
309. Matsumoto K, Matsumoto J, Nakamura T, et al. Hepatocyte growth factor-scatter factor induces tyrosine phosphorylation of focal adhesion kinase (p125-FAK) and promotes migration and invasion by oral squamous cell carcinoma cells. J Biol Chem 1994; 269: 31807-13
-
(1994)
J Biol Chem
, vol.269
, pp. 31807-31813
-
-
Matsumoto, K.1
Matsumoto, J.2
Nakamura, T.3
-
310
-
-
0029811745
-
Hepatocyte growth factor induces tyrosine phosphorylation of focal adhesion kinase (FAK) and paxillin and enhances cell-matrix interactions
-
310. Jiang WG, Hiscox S, Nakamura T, et al. Hepatocyte growth factor induces tyrosine phosphorylation of focal adhesion kinase (FAK) and paxillin and enhances cell-matrix interactions. Oncol Rep 1996; 3: 819-23
-
(1996)
Oncol Rep
, vol.3
, pp. 819-823
-
-
Jiang, W.G.1
Hiscox, S.2
Nakamura, T.3
-
311
-
-
0030948782
-
Prolactin stimulates the JAK2 and focal adhesion kinase pathways in human breast carcinoma T47-D cells
-
311. Canbay E, Norman M, Kilic E, et al. Prolactin stimulates the JAK2 and focal adhesion kinase pathways in human breast carcinoma T47-D cells. Biochem J 1997; 324: 231-6
-
(1997)
Biochem J
, vol.324
, pp. 231-236
-
-
Canbay, E.1
Norman, M.2
Kilic, E.3
-
312
-
-
0024356203
-
K562 leukemia cells transfected with the human c-fes gene acquire the ability to undergo myeloid differentiation
-
312. Yu G, Smithgall TE, Glazer RI. K562 leukemia cells transfected with the human c-fes gene acquire the ability to undergo myeloid differentiation. J Biol Chem 1989; 264: 10276-81
-
(1989)
J Biol Chem
, vol.264
, pp. 10276-10281
-
-
Yu, G.1
Smithgall, T.E.2
Glazer, R.I.3
-
313
-
-
0013657076
-
The protein kinases: Fes/Fps
-
Hardie G, Hanks S, editors. New York: Academic Press
-
313. Van de Ven WJM. The protein kinases: Fes/Fps. In: Hardie G, Hanks S, editors. The protein kinase facts book. New York: Academic Press, 1995: 92-4
-
(1995)
The Protein Kinase Facts Book
, pp. 92-94
-
-
Van De Ven, W.J.M.1
-
314
-
-
0024500460
-
Isolation and sequence analysis of a novel human tyrosine kinase
-
314. Hao QL, Heisterkamp N, Groffen J. Isolation and sequence analysis of a novel human tyrosine kinase. Mol Cell Biol 1989; 9: 1587-93
-
(1989)
Mol Cell Biol
, vol.9
, pp. 1587-1593
-
-
Hao, Q.L.1
Heisterkamp, N.2
Groffen, J.3
-
315
-
-
0021837498
-
Specific expression of the human cellular fps/fes-encoded protein NCP92 in normal and leukemic myeloid cells
-
315. Feldman RA, Gabrilove JL, Tam JP, et al. Specific expression of the human cellular fps/fes-encoded protein NCP92 in normal and leukemic myeloid cells. Proc Natl Acad Sci U S A 1985; 82: 2379-83
-
(1985)
Proc Natl Acad Sci U S A
, vol.82
, pp. 2379-2383
-
-
Feldman, R.A.1
Gabrilove, J.L.2
Tam, J.P.3
-
316
-
-
0021886559
-
Expression of the mammalian c-fes protein in hematopoietic cells and identification of a distinct fes-related protein
-
316. MacDonald I, Levy J, Pawson T. Expression of the mammalian c-fes protein in hematopoietic cells and identification of a distinct fes-related protein. Mol Cell Biol 1985; 5: 2543-51
-
(1985)
Mol Cell Biol
, vol.5
, pp. 2543-2551
-
-
Macdonald, I.1
Levy, J.2
Pawson, T.3
-
317
-
-
0021320926
-
Expression of cellular oncogenes in human malignancies
-
317. Slamon D, de Kemion JR, Verma IM, et al. Expression of cellular oncogenes in human malignancies. Science 1984; 224: 256-62
-
(1984)
Science
, vol.224
, pp. 256-262
-
-
Slamon, D.1
De Kemion, J.R.2
Verma, I.M.3
-
318
-
-
0028095405
-
The fps/fes protein-tyrosine kinase promotes angiogenesis in transgenic mice
-
318. Greer P, Haigh J, Mbamalu G, et al. The fps/fes protein-tyrosine kinase promotes angiogenesis in transgenic mice. Mol Cell Biol 1994; 14: 6755-63
-
(1994)
Mol Cell Biol
, vol.14
, pp. 6755-6763
-
-
Greer, P.1
Haigh, J.2
Mbamalu, G.3
-
319
-
-
0025604178
-
Complete coding sequence of a human B-raf cDNA and detection of B-raf protein kinase with isozyme specific antibodies
-
319. Sithanandam G, Koleh W, Duh FM, et al. Complete coding sequence of a human B-raf cDNA and detection of B-raf protein kinase with isozyme specific antibodies. Oncogene 1990; 5: 1775-80
-
(1990)
Oncogene
, vol.5
, pp. 1775-1780
-
-
Sithanandam, G.1
Koleh, W.2
Duh, F.M.3
-
320
-
-
0031041171
-
Differential regulation of Raf-1, A-raf, and B-raf by oncogenic Ras and tyrosine kinases
-
320. Marais R, Light Y, Paterson HF, et al. Differential regulation of Raf-1, A-Raf, and B-Raf by oncogenic Ras and tyrosine kinases. J Biol Chem 1997; 272: 4378-83
-
(1997)
J Biol Chem
, vol.272
, pp. 4378-4383
-
-
Marais, R.1
Light, Y.2
Paterson, H.F.3
-
321
-
-
0029126877
-
Neurofibromatosis type I and Ras-mediated signalling: Filling in the GAPs
-
321. Bernards A. Neurofibromatosis type I and Ras-mediated signalling: filling in the GAPs. Biochim Biophys Acta 1995; 1242: 43-59
-
(1995)
Biochim Biophys Acta
, vol.1242
, pp. 43-59
-
-
Bernards, A.1
-
322
-
-
0024294392
-
Guanosine triphosphatase activating protein (GAP) interacts with the p21 ras effector binding domain
-
322. Adari H, Lowy DR, Willumsen BF, et al. Guanosine triphosphatase activating protein (GAP) interacts with the p21 ras effector binding domain. Science 1988; 240: 518-21
-
(1988)
Science
, vol.240
, pp. 518-521
-
-
Adari, H.1
Lowy, D.R.2
Willumsen, B.F.3
-
323
-
-
0028074316
-
Phosphatidylinositol-3-OH kinase as a direct target of ras
-
323. Rodriguez-Viciana P, Warne PH, Dhand R, et al. Phosphatidylinositol-3-OH kinase as a direct target of ras. Nature 1994; 370: 527-32
-
(1994)
Nature
, vol.370
, pp. 527-532
-
-
Rodriguez-Viciana, P.1
Warne, P.H.2
Dhand, R.3
-
324
-
-
0026046956
-
Mutational analysis of a ras catalytic domain
-
324. Willumsen BM, Vass WC, Velu TJ, et al. Mutational analysis of a ras catalytic domain. Mol Cell Biol 1991; 11: 6026-33
-
(1991)
Mol Cell Biol
, vol.11
, pp. 6026-6033
-
-
Willumsen, B.M.1
Vass, W.C.2
Velu, T.J.3
-
325
-
-
6844252268
-
Selective inhibition of oncogenic ras-p21 in vivo by agents that block its interaction with jun-N-kinase (JNK) and jun proteins: Implications for the design of selective chemotherapeutic agents
-
325. Amar S, Glozman A, Chung D, et al. Selective inhibition of oncogenic ras-p21 in vivo by agents that block its interaction with jun-N-kinase (JNK) and jun proteins: implications for the design of selective chemotherapeutic agents. Cancer Chemother Pharmacol 1997; 41: 79-85
-
(1997)
Cancer Chemother Pharmacol
, vol.41
, pp. 79-85
-
-
Amar, S.1
Glozman, A.2
Chung, D.3
-
326
-
-
0030020333
-
Ras inhibitors
-
326. Hiwasa T. Ras inhibitors [review]. Oncol Rep 1994; 3: 7-14
-
(1994)
Oncol Rep
, vol.3
, pp. 7-14
-
-
Hiwasa, T.1
-
327
-
-
0032478610
-
Requirement of Ras-GTP-Raf complexes for activation of Raf-1 by protein kinase C
-
published erratum appears in Science 1998; 280: 987
-
327. Marais R, Light Y, Mason C, et al. Requirement of Ras-GTP-Raf complexes for activation of Raf-1 by protein kinase C [published erratum appears in Science 1998; 280: 987]. Science 1998; 280: 109-12
-
(1998)
Science
, vol.280
, pp. 109-112
-
-
Marais, R.1
Light, Y.2
Mason, C.3
-
328
-
-
0031036307
-
Raf-1/bcl-2 phosphorylation: A tep from microtubule damage to cell death
-
328. Blagosklonny MV, Giannakakou P, El-Deiry WS, et al. Raf-1/bcl-2 phosphorylation: a tep from microtubule damage to cell death. Cancer Res 1997; 57: 103-5
-
(1997)
Cancer Res
, vol.57
, pp. 103-105
-
-
Blagosklonny, M.V.1
Giannakakou, P.2
El-Deiry, W.S.3
-
329
-
-
0345498292
-
Bcl-2 targets the protein kinase Raf-1 to mitochondria
-
329. Wang HG, Rapp UR, Reed JC. Bcl-2 targets the protein kinase Raf-1 to mitochondria. Cell 1996; 87: 629-38
-
(1996)
Cell
, vol.87
, pp. 629-638
-
-
Wang, H.G.1
Rapp, U.R.2
Reed, J.C.3
-
330
-
-
0030916669
-
The proto-oncogene Bcl-2 and its role in regulating apoptosis
-
published erratum appears in Nat Med 1997; 3: 934
-
330. Kroemer G. The proto-oncogene Bcl-2 and its role in regulating apoptosis [published erratum appears in Nat Med 1997; 3: 934]. Nat Med 1997; 3: 614-20
-
(1997)
Nat Med
, vol.3
, pp. 614-620
-
-
Kroemer, G.1
-
331
-
-
0030979773
-
Double identity for proteins of the Bcl-2 family
-
331. Reed JC. Double identity for proteins of the Bcl-2 family. Nature 1997; 387: 773-6
-
(1997)
Nature
, vol.387
, pp. 773-776
-
-
Reed, J.C.1
-
332
-
-
0031895510
-
The Bax gene, the promoter of apoptosis, is mutated in genetically unstable cancers of the colorectum, stomach and endometrium
-
332. Ouyang H, Furukawa T, Abe T, et al. The Bax gene, the promoter of apoptosis, is mutated in genetically unstable cancers of the colorectum, stomach and endometrium. Clin Cancer Res 1998; 4: 1071-4
-
(1998)
Clin Cancer Res
, vol.4
, pp. 1071-1074
-
-
Ouyang, H.1
Furukawa, T.2
Abe, T.3
-
333
-
-
0032499218
-
Bax frameshift mutations in cell lines derived from human haematopoietic malignancies are associated with resistance to apoptosis and microsatellite instability
-
333. Brimmell M, Mendiola R, Mangion J, et al. Bax frameshift mutations in cell lines derived from human haematopoietic malignancies are associated with resistance to apoptosis and microsatellite instability. Oncogene 1998; 16: 1803-12
-
(1998)
Oncogene
, vol.16
, pp. 1803-1812
-
-
Brimmell, M.1
Mendiola, R.2
Mangion, J.3
-
334
-
-
0024376173
-
ras oncogenes in human cancer: A review
-
334. Bos JL. ras oncogenes in human cancer: a review. Cancer Res 1989; 49: 4682-9
-
(1989)
Cancer Res
, vol.49
, pp. 4682-4689
-
-
Bos, J.L.1
-
335
-
-
0029022018
-
Mutations or ras genes in human tumours
-
335. Kiaris H, Spandidos DA. Mutations or ras genes in human tumours [review]. Int J Oncol 1995; 7: 413-21
-
(1995)
Int J Oncol
, vol.7
, pp. 413-421
-
-
Kiaris, H.1
Spandidos, D.A.2
-
336
-
-
0032032627
-
CD95 (Fas)-induced caspase-mediated proteolysis of NF-κB
-
336. Ravi R, Bedi A, Fuchs EJ, et al. CD95 (Fas)-induced caspase-mediated proteolysis of NF-κB. Cancer Res 1998; 58: 882-6
-
(1998)
Cancer Res
, vol.58
, pp. 882-886
-
-
Ravi, R.1
Bedi, A.2
Fuchs, E.J.3
-
337
-
-
0024583137
-
Loss of heterozygosity at the c-raf locus in small cell lung carcinoma
-
337. Sithanandam G, Dean M, Brennscheidt U, et al. Loss of heterozygosity at the c-raf locus in small cell lung carcinoma. Oncogene 1989; 4: 451-5
-
(1989)
Oncogene
, vol.4
, pp. 451-455
-
-
Sithanandam, G.1
Dean, M.2
Brennscheidt, U.3
-
338
-
-
0031127372
-
Activation of Rf-1 in human pancreatic adenocarcinoma
-
338. Berger DH, Jardines, LA, Chang H, et al. Activation of Rf-1 in human pancreatic adenocarcinoma. J Surg Res 1997; 69: 199-204
-
(1997)
J Surg Res
, vol.69
, pp. 199-204
-
-
Berger, D.H.1
Jardines, L.A.2
Chang, H.3
-
339
-
-
0029183367
-
Raf-1 protein expression in human breast cancer cells
-
339. Callans LS, Naama H, Khandelwal M, et al. Raf-1 protein expression in human breast cancer cells. Anns Surg Oncol 1995; 2: 38-42
-
(1995)
Anns Surg Oncol
, vol.2
, pp. 38-42
-
-
Callans, L.S.1
Naama, H.2
Khandelwal, M.3
-
340
-
-
0031018758
-
Correlation of constitutive activation of raf-1 with morphological transformation and abrogation of tyrosine phosphorylation of distinct sets of proteins in human squamous carcinoma cells
-
340. Patel BK, Ray S, Whiteside TL, et al. Correlation of constitutive activation of raf-1 with morphological transformation and abrogation of tyrosine phosphorylation of distinct sets of proteins in human squamous carcinoma cells. Mol Carcinogen 1993; 18: 1-6
-
(1993)
Mol Carcinogen
, vol.18
, pp. 1-6
-
-
Patel, B.K.1
Ray, S.2
Whiteside, T.L.3
-
341
-
-
0029610406
-
Differential c-myc, c-jun, c-raf and p53 expression in squamous cell carcinoma of the head and neck: Implication in drug and radioresisiance
-
341. Riva C, Lavieille JP, Reyt E, et al. Differential c-myc, c-jun, c-raf and p53 expression in squamous cell carcinoma of the head and neck: implication in drug and radioresisiance. Eur J Cancer Oral Oncol 1995; 31B (Pt B): 384-91
-
(1995)
Eur J Cancer Oral Oncol
, vol.31 B
, Issue.PT B
, pp. 384-391
-
-
Riva, C.1
Lavieille, J.P.2
Reyt, E.3
-
342
-
-
0029898896
-
Raf-1 kinase, epidermal growth factor receptors, and mutant Ras proteins in colonic carcinomas
-
342. Eggstein S, Manthey G, Hirsch T, et al. Raf-1 kinase, epidermal growth factor receptors, and mutant Ras proteins in colonic carcinomas. Dig Dis Sci 1996; 41: 1069-75
-
(1996)
Dig Dis Sci
, vol.41
, pp. 1069-1075
-
-
Eggstein, S.1
Manthey, G.2
Hirsch, T.3
-
343
-
-
0027998224
-
Factor independence of human myeloid leukemia cell lines is associated with increased phosphorylation of the proto-oncogene Raf-1
-
343. Okuda K, Matulonis U, Salgia R, et al. Factor independence of human myeloid leukemia cell lines is associated with increased phosphorylation of the proto-oncogene Raf-1. Exp Hematol 1994; 22: 1111-7
-
(1994)
Exp Hematol
, vol.22
, pp. 1111-1117
-
-
Okuda, K.1
Matulonis, U.2
Salgia, R.3
-
344
-
-
0028286557
-
Overexpression of the Raf-1 proto-oncogene in human myeloid leukemia
-
344. Schmidt CA, Oettle H, Ludwig WD, et al. Overexpression of the Raf-1 proto-oncogene in human myeloid leukemia. Leuk Res 1994; 18: 409-13
-
(1994)
Leuk Res
, vol.18
, pp. 409-413
-
-
Schmidt, C.A.1
Oettle, H.2
Ludwig, W.D.3
-
345
-
-
0013635009
-
Raf-1 phosphorylation in human breast cancer cells
-
March 18-21, Los Angeles (CA)
-
345. Callans LS, Naama H, Khandelwal M, et al. Raf-1 phosphorylation in human breast cancer cells (Meeting abstract). Soc. Surg. Oncol., 46th Annual Cancer Symposium in Conjunction with Society of Head and Neck Surgeons; 1993 March 18-21, Los Angeles (CA), 20
-
(1993)
Soc. Surg. Oncol., 46th Annual Cancer Symposium in Conjunction with Society of Head and Neck Surgeons
, pp. 20
-
-
Callans, L.S.1
Naama, H.2
Khandelwal, M.3
-
346
-
-
0027312651
-
Nucleotide sequence analysis of c-raf-1 cDNA and promoter from a radiation-resistant human squamous carcinoma cell line: Deletion within exon 17
-
346. Patel BK, Kasid U. Nucleotide sequence analysis of c-raf-1 cDNA and promoter from a radiation-resistant human squamous carcinoma cell line: deletion within exon 17. Mol Carcinogen 1993; 8: 7-12
-
(1993)
Mol Carcinogen
, vol.8
, pp. 7-12
-
-
Patel, B.K.1
Kasid, U.2
-
347
-
-
0027457349
-
Oncogene activation: C-raf-1 gene mutations in experimental and naturally occurring tumors
-
347. Storm SM, Rapp UR. Oncogene activation: c-raf-1 gene mutations in experimental and naturally occurring tumors. Toxicology Lett 1993; 67: 201-10
-
(1993)
Toxicology Lett
, vol.67
, pp. 201-210
-
-
Storm, S.M.1
Rapp, U.R.2
-
348
-
-
0022885437
-
Recurrent deletion of the short arm of chromosome 3 in human renal cell carcinoma: Shift of the c-raf 1 locus
-
348. Teyssier JR, Henry I, Dozier C, et al. Recurrent deletion of the short arm of chromosome 3 in human renal cell carcinoma: shift of the c-raf 1 locus. J Natl Cancer Inst 1986; 77: 1187-95
-
(1986)
J Natl Cancer Inst
, vol.77
, pp. 1187-1195
-
-
Teyssier, J.R.1
Henry, I.2
Dozier, C.3
-
349
-
-
0024786623
-
Amplification of both c-myc and c-raf-1 oncogenes in a human osteosarcoma
-
349. Ikeda S, Sumii H, Akiyama K, et al. Amplification of both c-myc and c-raf-1 oncogenes in a human osteosarcoma. Jpn J Cancer Res 1989; 80: 6-9
-
(1989)
Jpn J Cancer Res
, vol.80
, pp. 6-9
-
-
Ikeda, S.1
Sumii, H.2
Akiyama, K.3
-
350
-
-
0025790481
-
Mos oncogene expression in human ovarian tumors
-
350. Xerri L, Charpin C, Hassoun J, et al. Mos oncogene expression in human ovarian tumors. Anticancer Res 1991; 11: 1629-34
-
(1991)
Anticancer Res
, vol.11
, pp. 1629-1634
-
-
Xerri, L.1
Charpin, C.2
Hassoun, J.3
-
351
-
-
0022399533
-
Presence of an allelic EcoRI restriction fragment of the c-mos locus in leukocyte and tumor cell DNAs of breast cancer patients
-
351. Lidereau R, Mathieu-Mahul D, Theillet C, et al. Presence of an allelic EcoRI restriction fragment of the c-mos locus in leukocyte and tumor cell DNAs of breast cancer patients. Proc Natl Acad Sci U S A 1985; 82: 7068-70
-
(1985)
Proc Natl Acad Sci U S A
, vol.82
, pp. 7068-7070
-
-
Lidereau, R.1
Mathieu-Mahul, D.2
Theillet, C.3
-
352
-
-
0024244851
-
Abnormal expression of the MOS proto-oncogene in human thyroid medullary carcinoma
-
352. Parkar MH, Seid JM, Stringer BM, et al. Abnormal expression of the MOS proto-oncogene in human thyroid medullary carcinoma. Cancer Lett 1988; 15: 185-9
-
(1988)
Cancer Lett
, vol.15
, pp. 185-189
-
-
Parkar, M.H.1
Seid, J.M.2
Stringer, B.M.3
-
353
-
-
0023628625
-
A single point mutation responsible for c-mos polymorphism in cancer patients
-
353. Lidereau R, Cole ST, Larsen CJ, et al. A single point mutation responsible for c-mos polymorphism in cancer patients. Oncogene 1987; 1: 235-7
-
(1987)
Oncogene
, vol.1
, pp. 235-237
-
-
Lidereau, R.1
Cole, S.T.2
Larsen, C.J.3
-
354
-
-
0013659711
-
Mutations of c-myc and c-mos genes lead to aberrant transcription of c-myc
-
354. Csaikl F, Mullauer L, Schwabe M, et al. Mutations of c-myc and c-mos genes lead to aberrant transcription of c-myc [abstract]. Blut 1987; 55: 244
-
(1987)
Blut
, vol.55
, pp. 244
-
-
Csaikl, F.1
Mullauer, L.2
Schwabe, M.3
-
355
-
-
0001582482
-
Molecular cloning of the AKT oncogene and its human homologous AKT1 and AKT2: Amplification of AKT1 in a primary human gastric adenocarcinoma
-
355. Staal SP. Molecular cloning of the AKT oncogene and its human homologous AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma. Proc Natl Acad Sci U S A 1987; 84: 5034-7
-
(1987)
Proc Natl Acad Sci U S A
, vol.84
, pp. 5034-5037
-
-
Staal, S.P.1
-
356
-
-
0013634836
-
Endogenous regulation of the protooncogene protein serine-threonine kinase, c-AKT by estradiol and insulin growth factor-1 in MCF-7 breast carcinoma cells
-
356. Ahmad S, Singh N, Bellacosa A, et al. Endogenous regulation of the protooncogene protein serine-threonine kinase, c-AKT by estradiol and insulin growth factor-1 in MCF-7 breast carcinoma cells [abstract]. Proc Am Assoc Cancer Res 1998; 38: 232
-
(1998)
Proc Am Assoc Cancer Res
, vol.38
, pp. 232
-
-
Ahmad, S.1
Singh, N.2
Bellacosa, A.3
-
357
-
-
4243691905
-
Functionally significant Gi-protein linked MAPK pathway in primary human hepatocellular carcinoma
-
357. Schmidt CM, McKillop IH, Cahill PA, et al. Functionally significant Gi-protein linked MAPK pathway in primary human hepatocellular carcinoma [abstract]. Hepatol 1997; 26: 263A
-
(1997)
Hepatol
, vol.26
-
-
Schmidt, C.M.1
McKillop, I.H.2
Cahill, P.A.3
-
358
-
-
4243733897
-
Hyperexpression of mitogen-activated protein kinase (p42-p44 MAPK) in malignant lymphoid neoplasms
-
358. Takahashi T, Murohashi I, Kishimoto K, et al. Hyperexpression of mitogen-activated protein kinase (p42-p44 MAPK) in malignant lymphoid neoplasms [abstract]. Blood 1997; 90: 165B
-
(1997)
Blood
, vol.90
-
-
Takahashi, T.1
Murohashi, I.2
Kishimoto, K.3
-
359
-
-
0029993628
-
MAPK activity is down-regulated in human colon adenocarcinoma: Correlation with PCK activity
-
359. Attar BM, Atten MJ, Holian O. MAPK activity is down-regulated in human colon adenocarcinoma: correlation with PCK activity. Anticancer Res 1996; 16: 395-9
-
(1996)
Anticancer Res
, vol.16
, pp. 395-399
-
-
Attar, B.M.1
Atten, M.J.2
Holian, O.3
-
360
-
-
4243691907
-
Growth regulation by the ras-MAPK pathway in human pancreatic ductal carcinoma
-
360. Frexes-Steed M, Woodard BA, Kern S, et al. Growth regulation by the ras-MAPK pathway in human pancreatic ductal carcinoma [abstract]. Gastroenterol 1997; 112: A564
-
(1997)
Gastroenterol
, vol.112
-
-
Frexes-Steed, M.1
Woodard, B.A.2
Kern, S.3
-
361
-
-
0013657709
-
IGF-I, insulin, and IL4 activated IRS1 in human breast cancer cells: Differential IRS1 tyrosine phosphorylation by IGF-I is associated with increased MAPK and PI3K activation
-
361. Yee D, Gooch JL, Jackson JG. IGF-I, insulin, and IL4 activated IRS1 in human breast cancer cells: Differential IRS1 tyrosine phosphorylation by IGF-I is associated with increased MAPK and PI3K activation [abstract]. Proc Am Assoc Cancer Res Ann Meeting 1997; 38: 435
-
(1997)
Proc Am Assoc Cancer Res Ann Meeting
, vol.38
, pp. 435
-
-
Yee, D.1
Gooch, J.L.2
Jackson, J.G.3
-
362
-
-
0027960533
-
Human T-cell leukemia-virus type-I tax activation of NF-kappa-B/Rel involves phosphorylation and degradation of I-kappa-B-alpha and rela (p65)-mediated induction of the c-rel gene
-
362. Sun SC, Elwood J, Beraud C, et al. Human T-cell leukemia-virus type-I tax activation of NF-kappa-B/Rel involves phosphorylation and degradation of I-kappa-B-alpha and rela (p65)-mediated induction of the c-rel gene. Mol Cell Biol 1994; 14: 7377-84
-
(1994)
Mol Cell Biol
, vol.14
, pp. 7377-7384
-
-
Sun, S.C.1
Elwood, J.2
Beraud, C.3
-
363
-
-
0028049074
-
The NF-kappa B transcription factor and cancer: High expression of NF-kappa B- and I kappa B-related proteins in tumor cell lines
-
363. Bours V, Dejardin E, Goujon-Letawe F, et al. The NF-kappa B transcription factor and cancer: high expression of NF-kappa B- and I kappa B-related proteins in tumor cell lines. Biochem Pharmacol 1994; 47: 145-9
-
(1994)
Biochem Pharmacol
, vol.47
, pp. 145-149
-
-
Bours, V.1
Dejardin, E.2
Goujon-Letawe, F.3
-
364
-
-
0026472154
-
Role of rel family genes in normal and malignant lymphoid cell growth
-
364. Gilmore TD. Role of rel family genes in normal and malignant lymphoid cell growth. Cancer Surv 1992; 15: 69-87
-
(1992)
Cancer Surv
, vol.15
, pp. 69-87
-
-
Gilmore, T.D.1
-
365
-
-
0029994199
-
Differential nuclear localization of p50, p52, and RelB proteins in human accessory cells of the immune response in situ
-
365. Feuillard J, Korner M, Israel A, et al. Differential nuclear localization of p50, p52, and RelB proteins in human accessory cells of the immune response in situ. Eur J Immunol 1996; 26: 2547-51
-
(1996)
Eur J Immunol
, vol.26
, pp. 2547-2551
-
-
Feuillard, J.1
Korner, M.2
Israel, A.3
-
366
-
-
0031440245
-
Aberrant nuclear factor-kappa-B-Rel expression and the pathogenesis of breast cancer
-
366. Sovak MA, Bellas RE, Kim DW, et al. Aberrant nuclear factor-kappa-B-Rel expression and the pathogenesis of breast cancer. J Clin Invest 1997; 100: 2952-60
-
(1997)
J Clin Invest
, vol.100
, pp. 2952-2960
-
-
Sovak, M.A.1
Bellas, R.E.2
Kim, D.W.3
-
367
-
-
0028866540
-
Highly-expressed p100/p52 (NFKB2) sequesters other NF-kappa B-relaled proteins in the cytoplasm of human breast cancer cells
-
367. Dejardin E, Bonizzi G, Bellahcene A, et al. Highly-expressed p100/p52 (NFKB2) sequesters other NF-kappa B-relaled proteins in the cytoplasm of human breast cancer cells. Oncogene 1995; 11: 1835-41
-
(1995)
Oncogene
, vol.11
, pp. 1835-1841
-
-
Dejardin, E.1
Bonizzi, G.2
Bellahcene, A.3
-
368
-
-
0013635259
-
Expression and regulation of nuclear factor-kappa B (NFκ-B)/REL in non-small cell lung carcinoma and transformed cell lines
-
368. Maxwell SA, Johnson M, Mukhopadhyay T. Expression and regulation of nuclear factor-kappa B (NFκ-B)/REL in non-small cell lung carcinoma and transformed cell lines [abstract]. Int J Oncol 1995; 7: 984
-
(1995)
Int J Oncol
, vol.7
, pp. 984
-
-
Maxwell, S.A.1
Johnson, M.2
Mukhopadhyay, T.3
-
369
-
-
0030666532
-
Expression of the neoplastic phenotype by human thyroid carcinoma cell lines requires NF-kappa-B p65 protein expression
-
369. Visconti R, Cerutti J, Battista S, et al. Expression of the neoplastic phenotype by human thyroid carcinoma cell lines requires NF-kappa-B p65 protein expression. Oncogene 1997; 15: 1987-94
-
(1997)
Oncogene
, vol.15
, pp. 1987-1994
-
-
Visconti, R.1
Cerutti, J.2
Battista, S.3
-
370
-
-
0029114985
-
Altered expression of the p50 subunit of the NF-kappa B transcription factor complex in non-small cell lung carcinoma
-
370. Mukhopadhyay T, Roth JA, Maxwell SA. Altered expression of the p50 subunit of the NF-kappa B transcription factor complex in non-small cell lung carcinoma. Oncogene 1995; 11: 999-1003
-
(1995)
Oncogene
, vol.11
, pp. 999-1003
-
-
Mukhopadhyay, T.1
Roth, J.A.2
Maxwell, S.A.3
-
371
-
-
0029417115
-
A novel NF-kappa B p65 spliced transcript lacking exons 6 and 7 in a non-small cell lung carcinoma cell line
-
371. Maxwell SA, Mukhopadhyay T. A novel NF-kappa B p65 spliced transcript lacking exons 6 and 7 in a non-small cell lung carcinoma cell line. Gene 1995; 166: 399-400
-
(1995)
Gene
, vol.166
, pp. 399-400
-
-
Maxwell, S.A.1
Mukhopadhyay, T.2
-
372
-
-
18844465632
-
Constitutive nuclear factor-kappa-B-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells
-
372. Bargou RC, Emmerich F, Krappmann D, et al. Constitutive nuclear factor-kappa-B-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells. J Clin Invest 1997; 100: 2961-9
-
(1997)
J Clin Invest
, vol.100
, pp. 2961-2969
-
-
Bargou, R.C.1
Emmerich, F.2
Krappmann, D.3
-
373
-
-
0030927167
-
Constitutive activation of NF-kappa-B during progression of breast cancer to hormone-independent growth
-
373. Nakshatri H, Bhat-Nakshatri P, Martin DA, et al. Constitutive activation of NF-kappa-B during progression of breast cancer to hormone-independent growth. Mol Cell Biol 1997; 17: 3629-39
-
(1997)
Mol Cell Biol
, vol.17
, pp. 3629-3639
-
-
Nakshatri, H.1
Bhat-Nakshatri, P.2
Martin, D.A.3
-
374
-
-
0031039111
-
Identification of a tumor-associated mutant of the NF-kappa B RelA gene with reduced DNA-binding and transactivating activities
-
374. Trecca D, Guerrini L, Frachhiolla NS, et al. Identification of a tumor-associated mutant of the NF-kappa B RelA gene with reduced DNA-binding and transactivating activities. Oncogene 1997; 14: 791-9
-
(1997)
Oncogene
, vol.14
, pp. 791-799
-
-
Trecca, D.1
Guerrini, L.2
Frachhiolla, N.S.3
-
375
-
-
0027512563
-
Mos and the cell cycle: The molecular basis of the transformed phenotype
-
375. Yew N, Strobel M, Vande Woude GF. Mos and the cell cycle: the molecular basis of the transformed phenotype. Curr Opin Genet Devel 1993; 3: 19-25
-
(1993)
Curr Opin Genet Devel
, vol.3
, pp. 19-25
-
-
Yew, N.1
Strobel, M.2
Vande Woude, G.F.3
-
376
-
-
0024313534
-
The c-mos proto-oncogene product is a cytostatic factor responsible for meiotic arrest in vertebrate eggs
-
376. Sagata N, Watanabe N, Vande Woude GF, Ikawa Y. The c-mos proto-oncogene product is a cytostatic factor responsible for meiotic arrest in vertebrate eggs. Nature 1989; 342: 512-8
-
(1989)
Nature
, vol.342
, pp. 512-518
-
-
Sagata, N.1
Watanabe, N.2
Vande Woude, G.F.3
Ikawa, Y.4
-
377
-
-
0013677512
-
Mos gen products
-
Hardie G, Hanks S, editors. New York: Academic Press
-
377. Vande Woude GF. Mos gen products (vertrebrates). In: Hardie G, Hanks S, editors. The protein kinase facts book. New York: Academic Press, 1995: 358-60
-
(1995)
The Protein Kinase Facts Book
, pp. 358-360
-
-
Vande Woude, G.F.1
-
378
-
-
0027491327
-
The protein kinase mos activates MAP kinase kinase in vitro and stimulates the MAP kinase pathway in mammalian somatic cells in vivo
-
378. Nebreda AR, Hill C, Gomez N, et al. The protein kinase mos activates MAP kinase kinase in vitro and stimulates the MAP kinase pathway in mammalian somatic cells in vivo. FEBS Lett 1993; 333: 183-7
-
(1993)
FEBS Lett
, vol.333
, pp. 183-187
-
-
Nebreda, A.R.1
Hill, C.2
Gomez, N.3
-
379
-
-
0029061185
-
Characterization of mek1 phosphorylation by the v-mos protein
-
379. Pham CD, Arlinghaus RB, Zheng CF, et al. Characterization of mek1 phosphorylation by the v-mos protein. Oncogene 1995; 10: 1683-8
-
(1995)
Oncogene
, vol.10
, pp. 1683-1688
-
-
Pham, C.D.1
Arlinghaus, R.B.2
Zheng, C.F.3
-
380
-
-
0028152333
-
MAP kinase kinase kinase, MAP kinase kinase and MAP kinase
-
380. Marshall CJ. MAP kinase kinase kinase, MAP kinase kinase and MAP kinase. Curr Opin Genet Dev 1994; 4: 82-9
-
(1994)
Curr Opin Genet Dev
, vol.4
, pp. 82-89
-
-
Marshall, C.J.1
-
381
-
-
0028073283
-
MAPKs: New JNK expands the group
-
381. Davis RJ. MAPKs: new JNK expands the group. Trends Biochem 1994; 19: 470-3
-
(1994)
Trends Biochem
, vol.19
, pp. 470-473
-
-
Davis, R.J.1
-
382
-
-
0028823892
-
Mitogen and stress response pathways: MAP kinase cascades and phosphatase regulation in mammals and yeast
-
382. Waskiewicz AJ, Cooper JA. Mitogen and stress response pathways: MAP kinase cascades and phosphatase regulation in mammals and yeast. Curr Opin Cell Biol 1995; 7: 798-805
-
(1995)
Curr Opin Cell Biol
, vol.7
, pp. 798-805
-
-
Waskiewicz, A.J.1
Cooper, J.A.2
-
383
-
-
0029079325
-
Activation of protein kinase cascades by osmotic shock
-
383. Matsuda S, Kawasaki H, Moriguchi T, et al. Activation of protein kinase cascades by osmotic shock. J Biol Chem 1995; 270: 12781-6
-
(1995)
J Biol Chem
, vol.270
, pp. 12781-12786
-
-
Matsuda, S.1
Kawasaki, H.2
Moriguchi, T.3
-
384
-
-
14444281569
-
Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways
-
384. Ichijo H, Nishida E, Irie K, et al. Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways. Science 1997; 275: 90-4
-
(1997)
Science
, vol.275
, pp. 90-94
-
-
Ichijo, H.1
Nishida, E.2
Irie, K.3
-
385
-
-
0029028962
-
Activation of yeast PBS2 MAPKK by MAPKKKs or by binding of an SH3-containing osmosensor
-
385. Maeda T, Takekawa M, Saito H. Activation of yeast PBS2 MAPKK by MAPKKKs or by binding of an SH3-containing osmosensor. Science 1995; 269: 554-8
-
(1995)
Science
, vol.269
, pp. 554-558
-
-
Maeda, T.1
Takekawa, M.2
Saito, H.3
-
386
-
-
0013674602
-
Involvement of Ras and apoptosis signal-regulating kinase (ASK-1) in activation of the JNK/SAPK cascade by treatment with paclitaxel or vinblastine
-
386. Wang TH, Henley DC, Ichijo H, et al. Involvement of Ras and apoptosis signal-regulating kinase (ASK-1) in activation of the JNK/SAPK cascade by treatment with paclitaxel or vinblastine [abstract]. Proc Am Assoc Cancer Res 1998; 39: 89
-
(1998)
Proc Am Assoc Cancer Res
, vol.39
, pp. 89
-
-
Wang, T.H.1
Henley, D.C.2
Ichijo, H.3
-
387
-
-
0032080283
-
Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1
-
387. Saitoh M, Nishitoh H, Fuji M, et al. Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1. EMBO J 1998; 17 (9): 2596-606
-
(1998)
EMBO J
, vol.17
, Issue.9
, pp. 2596-2606
-
-
Saitoh, M.1
Nishitoh, H.2
Fuji, M.3
-
388
-
-
0013635792
-
Functional interaction or human glutaminyl-t RNA synthetase and apoptosis signal-structure kinsase (Ask) 1
-
388. Ko YG, Seol WG, Kim TH, et al. Functional interaction or human glutaminyl-t RNA synthetase and apoptosis signal-structure kinsase (Ask) 1 [abstract]. Mol Biol Cell 1999; 10: 1909
-
(1999)
Mol Biol Cell
, vol.10
, pp. 1909
-
-
Ko, Y.G.1
Seol, W.G.2
Kim, T.H.3
-
390
-
-
0028111836
-
B-Raf-dependent regulation of the MEK-1/mitogen-activated protein kinase pathway in PC12 cells and regulation by cyclic AMP
-
390. Vaillancourt RR, Gardner AM, Johnson GL. B-Raf-dependent regulation of the MEK-1/mitogen-activated protein kinase pathway in PC12 cells and regulation by cyclic AMP. Mol Cell Biol 1994; 14: 6522-30
-
(1994)
Mol Cell Biol
, vol.14
, pp. 6522-6530
-
-
Vaillancourt, R.R.1
Gardner, A.M.2
Johnson, G.L.3
-
391
-
-
0029028358
-
B-raf protein isoforms interact with and phosphorylate mck-1 on serine residue-218 and residue 222
-
391. Papin CA, Eychene A, Brunet G, et al. B-raf protein isoforms interact with and phosphorylate mck-1 on serine residue-218 and residue 222. Oncogene 1995; 10: 1647-51
-
(1995)
Oncogene
, vol.10
, pp. 1647-1651
-
-
Papin, C.A.1
Eychene, A.2
Brunet, G.3
-
392
-
-
0026690922
-
Purification and characterization of mitogen-activated protein kinase activator(s) from epidermal growth factor-stimulated A431 cells
-
392. Seger R, Ahn NG, Posada J, et al. Purification and characterization of mitogen-activated protein kinase activator(s) from epidermal growth factor-stimulated A431 cells. J Biol Chem 1992; 257: 14373-81
-
(1992)
J Biol Chem
, vol.257
, pp. 14373-14381
-
-
Seger, R.1
Ahn, N.G.2
Posada, J.3
-
393
-
-
0025120244
-
Requirement for integration of signals from two distinct phosphorylation pathways for activation of MAP kinase
-
393. Anderson NG, Maller JL, Tonks NK, et al. Requirement for integration of signals from two distinct phosphorylation pathways for activation of MAP kinase. Nature 1990; 343: 651-3
-
(1990)
Nature
, vol.343
, pp. 651-653
-
-
Anderson, N.G.1
Maller, J.L.2
Tonks, N.K.3
-
394
-
-
0026642195
-
Induction of apoptosis in fibroblasts by the c-myc protein
-
394. Evan G, Wyllie A, Gilbert C, et al. Induction of apoptosis in fibroblasts by the c-myc protein. Cell 1992; 69: 119-25
-
(1992)
Cell
, vol.69
, pp. 119-125
-
-
Evan, G.1
Wyllie, A.2
Gilbert, C.3
-
395
-
-
0028237039
-
A biochemical function for ras - At last
-
395. Hall A. A biochemical function for ras - at last. Science 1994; 264: 1413-4
-
(1994)
Science
, vol.264
, pp. 1413-1414
-
-
Hall, A.1
-
396
-
-
0030907987
-
P13'K: Downstream AK-Tion blocks apoptosis
-
396. Franke TF, Kaplan DR, Cantley LC. P13'K: downstream AK-Tion blocks apoptosis. Cell 1997; 88: 435-7
-
(1997)
Cell
, vol.88
, pp. 435-437
-
-
Franke, T.F.1
Kaplan, D.R.2
Cantley, L.C.3
-
397
-
-
0030702123
-
Akt phosphorylation of BAD couples survival signals to the cell intrinsic death machinery
-
397. Datta SR, Dudek H, Tao X, et al. Akt phosphorylation of BAD couples survival signals to the cell intrinsic death machinery. Cell 1997; 91: 231-41
-
(1997)
Cell
, vol.91
, pp. 231-241
-
-
Datta, S.R.1
Dudek, H.2
Tao, X.3
-
398
-
-
0030884103
-
PKB/Akt: Connecting phosphoinositide 3-kinase to cell survival and beyond
-
398. Marte BM, Downward J. PKB/Akt: connecting phosphoinositide 3-kinase to cell survival and beyond. Trends Biochem Sci 1997; 22: 355-8
-
(1997)
Trends Biochem Sci
, vol.22
, pp. 355-358
-
-
Marte, B.M.1
Downward, J.2
-
399
-
-
0029992609
-
Suppression of TNF-α-induced apoptosis by NF-κB
-
399. Van Antwerp DJ, Martin SJ, Kafri T, et al. Suppression of TNF-α-induced apoptosis by NF-κB. Science 1996; 274: 787-89
-
(1996)
Science
, vol.274
, pp. 787-789
-
-
Van Antwerp, D.J.1
Martin, S.J.2
Kafri, T.3
-
400
-
-
0031017618
-
MAP3K-related kinase involved in NF-κB induction by TNF, CD95 and IL-1
-
400. Malinin NL, Boldin MP, Kovalenko AV, et al. MAP3K-related kinase involved in NF-κB induction by TNF, CD95 and IL-1. Nature 1997; 385: 540-4
-
(1997)
Nature
, vol.385
, pp. 540-544
-
-
Malinin, N.L.1
Boldin, M.P.2
Kovalenko, A.V.3
-
401
-
-
0030613646
-
Catalysis by a multiprotein IκB kinase complex
-
401. Maniatis T. Catalysis by a multiprotein IκB kinase complex. Science 1997; 278: 818-9
-
(1997)
Science
, vol.278
, pp. 818-819
-
-
Maniatis, T.1
-
402
-
-
0030611595
-
IκB kinase-B: NF-κB activation and complex formation with IκB kinase-α and NIK
-
402. Woronicz JD, Gao X, Cao Z, et al. IκB kinase-B: NF-κB activation and complex formation with IκB kinase-α and NIK. Science 1997; 278: 866-9
-
(1997)
Science
, vol.278
, pp. 866-869
-
-
Woronicz, J.D.1
Gao, X.2
Cao, Z.3
-
403
-
-
0028971289
-
Rel/NF kappa B/I kappa B family: Intimate tales of association and disassociation
-
403. Verma IM, Stevenson JK, Schwartz EM, et al. Rel/NF kappa B/I kappa B family: intimate tales of association and disassociation. Genes Dev 1995; 9: 2723-35
-
(1995)
Genes Dev
, vol.9
, pp. 2723-2735
-
-
Verma, I.M.1
Stevenson, J.K.2
Schwartz, E.M.3
-
404
-
-
0024294357
-
Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-kappa B transcription factor
-
404. Beuerle PA, Baltimore D. Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-kappa B transcription factor. Cell 1988; 53: 211-7
-
(1988)
Cell
, vol.53
, pp. 211-217
-
-
Beuerle, P.A.1
Baltimore, D.2
-
405
-
-
0025812292
-
Characterization of an immediate-early gene induced in adherent monocytes that encodes I kappa B-like activity
-
405. Haskill S, Berg AA, Tompkins SM, et al. Characterization of an immediate-early gene induced in adherent monocytes that encodes I kappa B-like activity. Cell 1991; 65: 1281-9
-
(1991)
Cell
, vol.65
, pp. 1281-1289
-
-
Haskill, S.1
Berg, A.A.2
Tompkins, S.M.3
-
406
-
-
0027078835
-
I kappa B/MAD-3 masks the nuclear localization signal of NF-kappa B p65 and requires the transactivation domain to inhibit NF-kappa B p65 DNA binding
-
406. Ganchi PA, Sun SC, Greene WC, et al. I kappa B/MAD-3 masks the nuclear localization signal of NF-kappa B p65 and requires the transactivation domain to inhibit NF-kappa B p65 DNA binding. Mol Biol Cell 1992; 3: 1339-52
-
(1992)
Mol Biol Cell
, vol.3
, pp. 1339-1352
-
-
Ganchi, P.A.1
Sun, S.C.2
Greene, W.C.3
-
407
-
-
0028861231
-
Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in breast cancer
-
407. Brown LF, Berse B, Jackman RW, et al. Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in breast cancer. Hum Pathol 1995; 26: 86-91
-
(1995)
Hum Pathol
, vol.26
, pp. 86-91
-
-
Brown, L.F.1
Berse, B.2
Jackman, R.W.3
-
408
-
-
0028929371
-
Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activation
-
408. Brockman JA, Scherer DC, McKinsey TA, et al. Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activation. Mol Cell Biol 1995; 15: 2809-18
-
(1995)
Mol Cell Biol
, vol.15
, pp. 2809-2818
-
-
Brockman, J.A.1
Scherer, D.C.2
McKinsey, T.A.3
-
409
-
-
0028978032
-
Phosphorylation of human I kappa B-alpha on serines 32 and 36 controls I kappa B-alpha proteolysis and NF-kappa B activation in response to diverse stimuli
-
409. Traenckner EB, Pahl HL, Henkel T, et al. Phosphorylation of human I kappa B-alpha on serines 32 and 36 controls I kappa B-alpha proteolysis and NF-kappa B activation in response to diverse stimuli. EMBO J 1995; 14: 2876-83
-
(1995)
EMBO J
, vol.14
, pp. 2876-2883
-
-
Traenckner, E.B.1
Pahl, H.L.2
Henkel, T.3
-
410
-
-
0029146930
-
Signal-induced site-specific phosphorylation targets 1 kappa B alpha to the ubiquitin-proteasome pathway
-
410. Chen Z, Hagler J, Palombella VJ, et al. Signal-induced site-specific phosphorylation targets 1 kappa B alpha to the ubiquitin-proteasome pathway. Genes Dev 1995; 9: 1586-97
-
(1995)
Genes Dev
, vol.9
, pp. 1586-1597
-
-
Chen, Z.1
Hagler, J.2
Palombella, V.J.3
-
411
-
-
0030685825
-
IKK-1 and IKK-2: Cytokine-activated IκB kinases essential for NF-κB activation
-
411. Mercurio F, Zhu H, Murray BW, et al. IKK-1 and IKK-2: cytokine-activated IκB kinases essential for NF-κB activation. Science 1997; 278: 860-6
-
(1997)
Science
, vol.278
, pp. 860-866
-
-
Mercurio, F.1
Zhu, H.2
Murray, B.W.3
-
412
-
-
0030610362
-
A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB
-
412. DiDonato JA, Hayakawa M, Rothwarf DM, et al. A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB. Nature 1997; 388: 548-54
-
(1997)
Nature
, vol.388
, pp. 548-554
-
-
DiDonato, J.A.1
Hayakawa, M.2
Rothwarf, D.M.3
-
413
-
-
0027722967
-
Cytoplasmic to nuclear signal transduction by mitogen-activated protein kinase and 90 kDa ribosomal S6 kinase
-
413. Chen RH, Tung R, Abate C, et al. Cytoplasmic to nuclear signal transduction by mitogen-activated protein kinase and 90 kDa ribosomal S6 kinase. Biochem Soc Trans 1993; 21: 895-900
-
(1993)
Biochem Soc Trans
, vol.21
, pp. 895-900
-
-
Chen, R.H.1
Tung, R.2
Abate, C.3
-
414
-
-
0029789643
-
Coupling of the RAS-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase
-
414. Xing J, Ginty DD, Greenberg ME. Coupling of the RAS-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase. Science 1996; 273: 969-3
-
(1996)
Science
, vol.273
, pp. 969-973
-
-
Xing, J.1
Ginty, D.D.2
Greenberg, M.E.3
-
415
-
-
0030851775
-
rsk) phosphorylates the N-terminal regulatory domain of IκBα and stimulates its degradation in vitro
-
rsk) phosphorylates the N-terminal regulatory domain of IκBα and stimulates its degradation in vitro. J Biol Chem 1997; 272: 21281-8
-
(1997)
J Biol Chem
, vol.272
, pp. 21281-21288
-
-
Ghoda, L.1
Lin, X.2
Greene, W.C.3
-
416
-
-
0028913550
-
A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domain
-
416. Boldin M, Varfolomeev EE, Pancer Z, et al. A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domain. J Biol Chem 1995; 270: 7795-8
-
(1995)
J Biol Chem
, vol.270
, pp. 7795-7798
-
-
Boldin, M.1
Varfolomeev, E.E.2
Pancer, Z.3
-
419
-
-
15844412409
-
FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex
-
419. Muzio M, Chinnaiyan AM, Kischkel FC, et al. FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex. Cell 1996; 85: 817-27
-
(1996)
Cell
, vol.85
, pp. 817-827
-
-
Muzio, M.1
Chinnaiyan, A.M.2
Kischkel, F.C.3
-
420
-
-
0030011398
-
Involvement of MACH, a novel MORT-1/FADD-interacting protease, in Fas/APO-1 and TNF receptor-induced cell death
-
420. Boldin MP, Goncharov TM, Goltsev YV, et al. Involvement of MACH, a novel MORT-1/FADD-interacting protease, in Fas/APO-1 and TNF receptor-induced cell death. Cell 1996; 85: 803-15
-
(1996)
Cell
, vol.85
, pp. 803-815
-
-
Boldin, M.P.1
Goncharov, T.M.2
Goltsev, Y.V.3
-
421
-
-
0028883850
-
Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins (CAP) form a death-inducing signaling complex (DISC) with the receptor
-
421. Kischkel FC, Hellbrandt S, Behrmann I, et al. Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins (CAP) form a death-inducing signaling complex (DISC) with the receptor. EMBO J 1995; 14: 5579-88
-
(1995)
EMBO J
, vol.14
, pp. 5579-5588
-
-
Kischkel, F.C.1
Hellbrandt, S.2
Behrmann, I.3
-
422
-
-
0030925774
-
FLICE is activated by association with the CD95 death-inducing signaling complex (DISC)
-
422. Medema JP, Scaffidi C, Kischkel FC, et al. FLICE is activated by association with the CD95 death-inducing signaling complex (DISC). EMBO J 1997; 16: 2794-804
-
(1997)
EMBO J
, vol.16
, pp. 2794-2804
-
-
Medema, J.P.1
Scaffidi, C.2
Kischkel, F.C.3
-
423
-
-
0031952224
-
Lymphocyte granule-mediated apoptosis: Matters of viral mimicry and deadly proteases
-
423. Froelich CJ, Dixit VM, Yang X. Lymphocyte granule-mediated apoptosis: matters of viral mimicry and deadly proteases. Immunol Today 1998; 19: 30-6
-
(1998)
Immunol Today
, vol.19
, pp. 30-36
-
-
Froelich, C.J.1
Dixit, V.M.2
Yang, X.3
-
424
-
-
0027219918
-
Signals and genes in the control of the cell cycle progression
-
424. Müller R, Mumberg D, Lucibello FC. Signals and genes in the control of the cell cycle progression. BBA 1993; 1155: 151-79
-
(1993)
BBA
, vol.1155
, pp. 151-179
-
-
Müller, R.1
Mumberg, D.2
Lucibello, F.C.3
-
425
-
-
0028918028
-
Transcriptional regulation during the mammalian cell cycle
-
425. Müller R. Transcriptional regulation during the mammalian cell cycle. Trends Genet 1995; 11: 173-8
-
(1995)
Trends Genet
, vol.11
, pp. 173-178
-
-
Müller, R.1
-
426
-
-
0027983092
-
Differential induction of 'metabolic genes' after mitogen stimulation and during normal cell cycle progression
-
426. Bürger C, Wick M, Brüsselbach S, et al. Differential induction of 'metabolic genes' after mitogen stimulation and during normal cell cycle progression. J Cell Sci 1994; 107: 241-52
-
(1994)
J Cell Sci
, vol.107
, pp. 241-252
-
-
Bürger, C.1
Wick, M.2
Brüsselbach, S.3
-
427
-
-
0028568315
-
Cell cycle control and cancer
-
427. Hartwell LH, Kastan MB. Cell cycle control and cancer. Science 1994; 266: 1821-8
-
(1994)
Science
, vol.266
, pp. 1821-1828
-
-
Hartwell, L.H.1
Kastan, M.B.2
-
428
-
-
0028053581
-
Cell cycle checkpoints
-
428. Murray A. Cell cycle checkpoints. Curr Opin Cell Biol 1994; 6: 872-6
-
(1994)
Curr Opin Cell Biol
, vol.6
, pp. 872-876
-
-
Murray, A.1
-
429
-
-
0027938209
-
Cyclins and cancer. II: Cyclin D and cdk inhibitors come of age
-
429. Hunter T, Pines J. Cyclins and cancer. II: Cyclin D and cdk inhibitors come of age. Cell 1994; 79: 573-82
-
(1994)
Cell
, vol.79
, pp. 573-582
-
-
Hunter, T.1
Pines, J.2
-
430
-
-
0028072520
-
Joining the complex: Cyclin-dependent kinase inhibitory proteins and the cell cycle
-
430. Peter M, Herskowitz I. Joining the complex: cyclin-dependent kinase inhibitory proteins and the cell cycle. Cell 1984; 79: 181-4
-
(1984)
Cell
, vol.79
, pp. 181-184
-
-
Peter, M.1
Herskowitz, I.2
-
431
-
-
0028168242
-
p15INK4B is a potential effector of TGFfl-induced cell cycle arrest
-
431. Hannon GF, Beach D. p15INK4B is a potential effector of TGFfl-induced cell cycle arrest. Nature 1994; 371: 257-61
-
(1994)
Nature
, vol.371
, pp. 257-261
-
-
Hannon, G.F.1
Beach, D.2
-
432
-
-
0028582034
-
Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related cdk6 inhibitor, correlates with wild-type pRb function
-
432. Guan KL, Jenkins CW, Li Y, et al. Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related cdk6 inhibitor, correlates with wild-type pRb function. Genes Dev 1994; 8: 2939-52
-
(1994)
Genes Dev
, vol.8
, pp. 2939-2952
-
-
Guan, K.L.1
Jenkins, C.W.2
Li, Y.3
-
433
-
-
0028342664
-
Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen
-
433. Noda A, Ning Y, Venable SF, Pereira-Smith OM, et al. Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen. Exp Cell Res 1994; 211: 90
-
(1994)
Exp Cell Res
, vol.211
, pp. 90
-
-
Noda, A.1
Ning, Y.2
Venable, S.F.3
Pereira-Smith, O.M.4
-
434
-
-
0027182223
-
Crystal structure of cyclin-dependent kinase 2
-
434. DeBondt HL, Rosenblatt J, Jancarik J, et al. Crystal structure of cyclin-dependent kinase 2. Nature 1993; 363: 595-602
-
(1993)
Nature
, vol.363
, pp. 595-602
-
-
DeBondt, H.L.1
Rosenblatt, J.2
Jancarik, J.3
-
435
-
-
0027465945
-
Sequences within the conserved cyclin box of human cyclin A are sufficient for binding to and activation of cdc2 kinase
-
435. Lees EM, Harlow E. Sequences within the conserved cyclin box of human cyclin A are sufficient for binding to and activation of cdc2 kinase. Mol Cell Biol 1993; 13: 1194-201
-
(1993)
Mol Cell Biol
, vol.13
, pp. 1194-1201
-
-
Lees, E.M.1
Harlow, E.2
-
436
-
-
0028174131
-
Mutational analysis supports a structural model for the cell cycle kinase p34
-
436. Endicott JA, Nurse P, Johnson LN. Mutational analysis supports a structural model for the cell cycle kinase p34. Protein Eng 1994; 7: 243-53
-
(1994)
Protein Eng
, vol.7
, pp. 243-253
-
-
Endicott, J.A.1
Nurse, P.2
Johnson, L.N.3
-
437
-
-
0028138670
-
The function(s) of CAK, the p34cdc2-activating kinase
-
437. Solomon MJ. The function(s) of CAK, the p34cdc2-activating kinase. Trends Biochem Sci 1994; 19: 496-500
-
(1994)
Trends Biochem Sci
, vol.19
, pp. 496-500
-
-
Solomon, M.J.1
-
438
-
-
0025936623
-
cdc2 phosphorylation is required for its interaction with cyclin
-
438. Ducommun B, Brambilla P, Felix MA, et al. cdc2 phosphorylation is required for its interaction with cyclin. EMBO J 1991 10: 3311-9
-
(1991)
EMBO J
, vol.10
, pp. 3311-3319
-
-
Ducommun, B.1
Brambilla, P.2
Felix, M.A.3
-
439
-
-
0028950016
-
Effects of phosphorylation by CAK on cyclin binding by cdc2 and cdk2
-
439. Desai D, Wessling HC, Fisher RP, et al. Effects of phosphorylation by CAK on cyclin binding by cdc2 and cdk2. Mol Cell Biol 1995; 15: 345-50
-
(1995)
Mol Cell Biol
, vol.15
, pp. 345-350
-
-
Desai, D.1
Wessling, H.C.2
Fisher, R.P.3
-
440
-
-
0028021003
-
Substrate specificity of cdc2 kinase from human HeLa cells as determined with synthetic peptides and molecular modelling
-
440. Zhang J, Sanchez RJ, Wang S, et al. Substrate specificity of cdc2 kinase from human HeLa cells as determined with synthetic peptides and molecular modelling. Arch Biochem Biophys 1994; 351: 415-24
-
(1994)
Arch Biochem Biophys
, vol.351
, pp. 415-424
-
-
Zhang, J.1
Sanchez, R.J.2
Wang, S.3
-
441
-
-
0029948789
-
Cyclin C/cdk8 is a novel CTD kinase associated with RNA polymeraxe II
-
441. Rickert P, Seghezzi W, Shanahan F, et al. Cyclin C/cdk8 is a novel CTD kinase associated with RNA polymeraxe II. Oncogene 1996; 12: 2631-40
-
(1996)
Oncogene
, vol.12
, pp. 2631-2640
-
-
Rickert, P.1
Seghezzi, W.2
Shanahan, F.3
-
442
-
-
0026319225
-
Specific activation of cdc25 tyrosine phosphatases by B-type cyclin: Evidence for multiple roles of mitotic cyclins
-
442. Galaktionov K, Beach D. Specific activation of cdc25 tyrosine phosphatases by B-type cyclin: evidence for multiple roles of mitotic cyclins. Cell 1991; 67: 1181-94
-
(1991)
Cell
, vol.67
, pp. 1181-1194
-
-
Galaktionov, K.1
Beach, D.2
-
443
-
-
0027482633
-
Functional analysis of the P box, a domain in cyclin B required for the activation of Cdc25
-
443. Zheng XF, Ruderman JV. Functional analysis of the P box, a domain in cyclin B required for the activation of Cdc25. Cell 1993; 78: 155-64
-
(1993)
Cell
, vol.78
, pp. 155-164
-
-
Zheng, X.F.1
Ruderman, J.V.2
-
444
-
-
0028915222
-
Molecular foundations of cancer: New targets for intervention
-
444. Karp JE, Broder S. Molecular foundations of cancer: new targets for intervention. Nat Med 1995; 1: 309-20
-
(1995)
Nat Med
, vol.1
, pp. 309-320
-
-
Karp, J.E.1
Broder, S.2
-
445
-
-
6844226190
-
Prevalence of p16 and CDK4 germline mutations in 48 melanoma-prone families in France
-
445. Soufir N, Avril MF, Chompret A, et al. Prevalence of p16 and CDK4 germline mutations in 48 melanoma-prone families in France. Human Mol Genetics 1998; 7: 209-16
-
(1998)
Human Mol Genetics
, vol.7
, pp. 209-216
-
-
Soufir, N.1
Avril, M.F.2
Chompret, A.3
-
446
-
-
0028978274
-
INK4a insensitive CDK4 mutant targeted by cytolytic T lymphocyte in a human melanoma
-
INK4a insensitive CDK4 mutant targeted by cytolytic T lymphocyte in a human melanoma. Science 1995; 269: 2181-4
-
(1995)
Science
, vol.269
, pp. 2181-2184
-
-
Wölfel, T.1
Hauer, M.2
Schneider, J.3
-
447
-
-
0027530449
-
Redundant cyclin overexpression and gene amplification in breast cancer cells
-
447. Keyomarsi K, Pardee AB. Redundant cyclin overexpression and gene amplification in breast cancer cells. Proc Natl Acad Sci U S A 1993; 90: 1112-26
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 1112-1126
-
-
Keyomarsi, K.1
Pardee, A.B.2
-
448
-
-
0027955197
-
Cyclin E, a potential prognostic marker for breast cancer
-
448. Keyomarsi K, O'Leary N, Molnar G, et al. Cyclin E, a potential prognostic marker for breast cancer. Cancer Res 1994; 54: 380-5
-
(1994)
Cancer Res
, vol.54
, pp. 380-385
-
-
Keyomarsi, K.1
O'Leary, N.2
Molnar, G.3
-
449
-
-
0029033861
-
The retinoblastoma protein and cell cycle control
-
449. Weinberg RA. The retinoblastoma protein and cell cycle control. Cell 1995; 81: 323-30
-
(1995)
Cell
, vol.81
, pp. 323-330
-
-
Weinberg, R.A.1
-
450
-
-
0031831681
-
The retinoblastoma gene family: Cousins with overlapping interests
-
450. Mulligan GJ, Jacks T. The retinoblastoma gene family: cousins with overlapping interests. Trends Genet 1998; 14: 223
-
(1998)
Trends Genet
, vol.14
, pp. 223
-
-
Mulligan, G.J.1
Jacks, T.2
-
451
-
-
0032437776
-
Role of the retinoblastoma protein family, pRb, p107 and p130 in the negative control of cell growth
-
451. Grana X, Garriga J, Mayol X. Role of the retinoblastoma protein family, pRb, p107 and p130 in the negative control of cell growth. Oncogene 1998; 17: 3365-83
-
(1998)
Oncogene
, vol.17
, pp. 3365-3383
-
-
Grana, X.1
Garriga, J.2
Mayol, X.3
-
452
-
-
0029807115
-
Flavopiridol (L86-8275; NSC 64890), a new kinase inhibitor for tumor therapy
-
452. Sedlacek HH, Czech J, Naik R, et al. Flavopiridol (L86-8275; NSC 64890), a new kinase inhibitor for tumor therapy. Int J Oncol 1996; 9: 1143-68
-
(1996)
Int J Oncol
, vol.9
, pp. 1143-1168
-
-
Sedlacek, H.H.1
Czech, J.2
Naik, R.3
-
453
-
-
0013675970
-
SU101, and not its major metabolite, inhibits PDGF-dependent receptor tyrosine phosphorylation, cell cycle progression, and human tumor cell growth
-
453. Lipson KE, Wang X, Chen H, et al. SU101, and not its major metabolite, inhibits PDGF-dependent receptor tyrosine phosphorylation, cell cycle progression, and human tumor cell growth. Proc Am Assoc Cancer Res 1998; 39: 558
-
(1998)
Proc Am Assoc Cancer Res
, vol.39
, pp. 558
-
-
Lipson, K.E.1
Wang, X.2
Chen, H.3
-
454
-
-
0013635177
-
Selective inhibition of PDGF-dependent receptor tyrosine phosphorylation and MAP kinase activation by tryptophan derivatives
-
454. Blaskovich MA, Wang H, Hamilton AD, et al. Selective inhibition of PDGF-dependent receptor tyrosine phosphorylation and MAP kinase activation by tryptophan derivatives [abstract]. Proc Am Assoc Cancer Res 1998; 39: 559
-
(1998)
Proc Am Assoc Cancer Res
, vol.39
, pp. 559
-
-
Blaskovich, M.A.1
Wang, H.2
Hamilton, A.D.3
-
455
-
-
0001360234
-
Characterization of the in vivo activity of a novel EGF receptor family kinase inhibitor, PD 169414
-
455. Vincent PW, Akinson BE, Zhou H, et al. Characterization of the in vivo activity of a novel EGF receptor family kinase inhibitor, PD 169414 [abstract]. Proc Am Assoc Cancer Res 1998; 39: 560
-
(1998)
Proc Am Assoc Cancer Res
, vol.39
, pp. 560
-
-
Vincent, P.W.1
Akinson, B.E.2
Zhou, H.3
-
456
-
-
0001360233
-
CP-358,774, a selective EGFR kinase inhibitor, inhibits phosphorylation of SHC and retinoblastoma protein in human tumor xenografts
-
456. Miller PE, Robinson J, Moyer JD, et al. CP-358,774, a selective EGFR kinase inhibitor, inhibits phosphorylation of SHC and retinoblastoma protein in human tumor xenografts [abstract]. Proc Am Assoc Cancer Res 1998; 39: 560
-
(1998)
Proc Am Assoc Cancer Res
, vol.39
, pp. 560
-
-
Miller, P.E.1
Robinson, J.2
Moyer, J.D.3
-
457
-
-
0013635696
-
CGP 59326, a potent protein tyrosine kinase (PTK) inhibitor which selectively blocks growth of epidermal growth factor receptor (EGFR) expressing tumor cells
-
457. Mett H, Buchdunger E. Müller M. CGP 59326, a potent protein tyrosine kinase (PTK) inhibitor which selectively blocks growth of epidermal growth factor receptor (EGFR) expressing tumor cells [abstract]. Proc Am Assoc Cancer Res 1998; 39: 560
-
(1998)
Proc Am Assoc Cancer Res
, vol.39
, pp. 560
-
-
Mett, H.1
Buchdunger, E.2
Müller, M.3
-
458
-
-
0001360236
-
SU54I6: A potent and selective Flk-1/KDR kinase inhibitor that blocks Flk-1 phosphorylation, endothelial cell mitogenesis and tumor growth
-
458. Fong TAT, Shawver LK, App H, et al. SU54I6: a potent and selective Flk-1/KDR kinase inhibitor that blocks Flk-1 phosphorylation, endothelial cell mitogenesis and tumor growth. Proc Am Assoc Cancer Res 1998; 39: 560
-
(1998)
Proc Am Assoc Cancer Res
, vol.39
, pp. 560
-
-
Fong, T.A.T.1
Shawver, L.K.2
App, H.3
-
459
-
-
0013656553
-
Effects of c-src selective pyrido[2,3-d]-pyrimidine tyrosine kinase inhibitors on the phophorylation of p130cas, paxillin, and STAT3 and on proliferation in human carcinoma cell lines
-
459. Kraker AJ, Moore CW, Hartl BG, et al. Effects of c-src selective pyrido[2,3-d]-pyrimidine tyrosine kinase inhibitors on the phophorylation of p130cas, paxillin, and STAT3 and on proliferation in human carcinoma cell lines [abstract]. Proc Am Assoc Cancer Res 1998; 39: 559
-
(1998)
Proc Am Assoc Cancer Res
, vol.39
, pp. 559
-
-
Kraker, A.J.1
Moore, C.W.2
Hartl, B.G.3
-
460
-
-
0013681979
-
Design of a highly potent inhibitor of Grb2 SH2 domain with cellular and in vivo activity
-
460. Gay B, Furet P, Fretz H, et al. Design of a highly potent inhibitor of Grb2 SH2 domain with cellular and in vivo activity [abstract]. Proc Am Assoc Cancer Res 1998; 39: 559
-
(1998)
Proc Am Assoc Cancer Res
, vol.39
, pp. 559
-
-
Gay, B.1
Furet, P.2
Fretz, H.3
-
461
-
-
0000161606
-
Preclinical evaluation of CGP 57148, a potent protein-tyrosine kinase inhibitor as a therapeutic agent for PH+ leukemias and solid tumors
-
461. Buchdunger E, Cioiffi C, Cozens R, et al. Preclinical evaluation of CGP 57148, a potent protein-tyrosine kinase inhibitor as a therapeutic agent for PH+ leukemias and solid tumors [abstract]. Proc Am Assoc Cancer Res 1998; 39: 559
-
(1998)
Proc Am Assoc Cancer Res
, vol.39
, pp. 559
-
-
Buchdunger, E.1
Cioiffi, C.2
Cozens, R.3
-
462
-
-
0000784537
-
Identification of potent, selective kinase inhibitors of
-
462. Heimbrook DC, Huber HE, Stordivant SM, et al. Identification of potent, selective kinase inhibitors of Raf. Proc Am Assoc Cancer Res 1998; 39: 558
-
(1998)
Raf. Proc Am Assoc Cancer Res
, vol.39
, pp. 558
-
-
Heimbrook, D.C.1
Huber, H.E.2
Stordivant, S.M.3
-
463
-
-
0000784536
-
CGP 60474, a protein kinase inhibitor with potent antitumor activity in vivo at well tolerated doses
-
463. Meyer T, Zimmermann J, Geiger T, et al. CGP 60474, a protein kinase inhibitor with potent antitumor activity in vivo at well tolerated doses [abstract]. Proc Am Assoc Cancer Res 1998; 39: 558
-
(1998)
Proc Am Assoc Cancer Res
, vol.39
, pp. 558
-
-
Meyer, T.1
Zimmermann, J.2
Geiger, T.3
-
464
-
-
0031670668
-
Phase I trial of a novel cyclin-dependent kinase inhibitor flavopiridol in patients with refractory neoplasms
-
464. Senderowicz A, Headlee D, Stinson S, et al. Phase I trial of a novel cyclin-dependent kinase inhibitor flavopiridol in patients with refractory neoplasms. Clin Oncol 1998; 16 (9): 2986-99
-
(1998)
Clin Oncol
, vol.16
, Issue.9
, pp. 2986-2999
-
-
Senderowicz, A.1
Headlee, D.2
Stinson, S.3
-
467
-
-
0000201912
-
DNA fragmentation and apoptosis of lymphoma and prostate cancer cell lines after flavopiridol treatment
-
467. Parker BW, Senderowicz AM, Nieves-Neira W, et al. DNA fragmentation and apoptosis of lymphoma and prostate cancer cell lines after flavopiridol treatment [abstract]. Proc Am Assoc Cancer Res 1996; 37: 398
-
(1996)
Proc Am Assoc Cancer Res
, vol.37
, pp. 398
-
-
Parker, B.W.1
Senderowicz, A.M.2
Nieves-Neira, W.3
-
468
-
-
0001627298
-
The protein kinase C inhibitors UCN-01 and flavopiridol significantly enhance the cytotoxic effect of chemotherapy by promoting apoptosis in gastric and breast cancer cells
-
468. Schwartz GK, Farsi K, Danso D, et al. The protein kinase C inhibitors UCN-01 and flavopiridol significantly enhance the cytotoxic effect of chemotherapy by promoting apoptosis in gastric and breast cancer cells [abstract]. Proc Am Soc Oncol 1996; 15: 501
-
(1996)
Proc Am Soc Oncol
, vol.15
, pp. 501
-
-
Schwartz, G.K.1
Farsi, K.2
Danso, D.3
-
469
-
-
0040379168
-
Cell cycle-independent induction of apoptosis by the anti-tumor drug Flavopiridol in endothelial cells
-
469. Brüsselbach S, Nettelbeck DM, Sedlacek HH, et al. Cell cycle-independent induction of apoptosis by the anti-tumor drug Flavopiridol in endothelial cells. Int J Cancer 1998; 77: 146-52
-
(1998)
Int J Cancer
, vol.77
, pp. 146-152
-
-
Brüsselbach, S.1
Nettelbeck, D.M.2
Sedlacek, H.H.3
-
470
-
-
0029904810
-
Flavopiridol: A cytotoxic flavone that induces cell death in noncycling A549 human lung carcinoma cells
-
470. Bible KC, Kaufmann SM. Flavopiridol: a cytotoxic flavone that induces cell death in noncycling A549 human lung carcinoma cells. Cancer Res 1996; 56: 4856-61
-
(1996)
Cancer Res
, vol.56
, pp. 4856-4861
-
-
Bible, K.C.1
Kaufmann, S.M.2
-
471
-
-
0029903594
-
Involvement of hydrogen peroxide production in erbstatin-induced apoptosis in human small cell lung carcinoma cells
-
471. Simizu S, Imoto M, Masuda N, et al. Involvement of hydrogen peroxide production in erbstatin-induced apoptosis in human small cell lung carcinoma cells. Cancer Res 1996; 56: 4978-82
-
(1996)
Cancer Res
, vol.56
, pp. 4978-4982
-
-
Simizu, S.1
Imoto, M.2
Masuda, N.3
-
472
-
-
0031570414
-
The tyrphostin AG17 induces apoptosis and inhibition of cdk2 activity in a lymphoma cell line that overexpresses bcl-2
-
472. Palumbo GA, Yarom N, Gazit A, et al. The tyrphostin AG17 induces apoptosis and inhibition of cdk2 activity in a lymphoma cell line that overexpresses bcl-2. Cancer Res 1997; 57: 2434-9
-
(1997)
Cancer Res
, vol.57
, pp. 2434-2439
-
-
Palumbo, G.A.1
Yarom, N.2
Gazit, A.3
-
473
-
-
0030774045
-
Induction of apoptosis and cell cycle arrest by CP-358,774, an inhibitor of epidermal growth factor receptor tyrosine kinase
-
473. Moyer JD, Barbacci EG, Iwata KK, et al. Induction of apoptosis and cell cycle arrest by CP-358,774, an inhibitor of epidermal growth factor receptor tyrosine kinase. Cancer Res 1997; 57: 4838-48
-
(1997)
Cancer Res
, vol.57
, pp. 4838-4848
-
-
Moyer, J.D.1
Barbacci, E.G.2
Iwata, K.K.3
-
474
-
-
0028108990
-
Induction of apoptosis by quercetin: Involvement of heat shock protein
-
474. Wei Y, Zhao X, Kariya Y, et al. Induction of apoptosis by quercetin: involvement of heat shock protein. Cancer Res 1994; 54: 4952-7
-
(1994)
Cancer Res
, vol.54
, pp. 4952-4957
-
-
Wei, Y.1
Zhao, X.2
Kariya, Y.3
-
475
-
-
0023664272
-
Genistein, a specific inhibitor of tyrosine-specific protein kinases
-
475. Akiyama T, Ishida J, Nakagawa S, et al. Genistein, a specific inhibitor of tyrosine-specific protein kinases. J Biol Chem 1987; 262: 5592-5
-
(1987)
J Biol Chem
, vol.262
, pp. 5592-5595
-
-
Akiyama, T.1
Ishida, J.2
Nakagawa, S.3
-
476
-
-
0025189757
-
Induction of mammalian topoisomerase II-dependent DNA cleavage by non-intercalative flavonoids, genistein, and phorbol
-
476. Yamashita Y, Kawada S, Nakano H. Induction of mammalian topoisomerase II-dependent DNA cleavage by non-intercalative flavonoids, genistein, and phorbol. Biochem Pharmacol 1990; 39: 187-93
-
(1990)
Biochem Pharmacol
, vol.39
, pp. 187-193
-
-
Yamashita, Y.1
Kawada, S.2
Nakano, H.3
-
477
-
-
0025363503
-
Induction of differentiation and DNA strand breakage in human HL-60 and K-562 leukemia cells by genistein
-
477. Constantinou A, Kiguchi K, Huberman E. Induction of differentiation and DNA strand breakage in human HL-60 and K-562 leukemia cells by genistein. Cancer Res 1990; 50: 2618-24
-
(1990)
Cancer Res
, vol.50
, pp. 2618-2624
-
-
Constantinou, A.1
Kiguchi, K.2
Huberman, E.3
-
478
-
-
0024238244
-
Effect of genistein on topoisomerase activity and on the growth of (Val 12) Ha-ras-transformed NHI-3T3 cells
-
478. Okura A, Arakawa H, Oka H, et al. Effect of genistein on topoisomerase activity and on the growth of (Val 12) Ha-ras-transformed NHI-3T3 cells. Biochem Biophys Res Commun 1988; 157: 183-9
-
(1988)
Biochem Biophys Res Commun
, vol.157
, pp. 183-189
-
-
Okura, A.1
Arakawa, H.2
Oka, H.3
-
479
-
-
0030777108
-
Enhancement of experimental colon cancer by genistein
-
479. Rao CV, Wang CX, Simi B, et al. Enhancement of experimental colon cancer by genistein. Cancer Res 1997; 57: 3717-22
-
(1997)
Cancer Res
, vol.57
, pp. 3717-3722
-
-
Rao, C.V.1
Wang, C.X.2
Simi, B.3
-
480
-
-
0031034001
-
Estrogenic and antiproliferative properties of genistein and other flavonoids in human breast cancer cells in vitro
-
480. Zava DT, Duwe G. Estrogenic and antiproliferative properties of genistein and other flavonoids in human breast cancer cells in vitro. Nutr Cancer 1997; 27: 31-40
-
(1997)
Nutr Cancer
, vol.27
, pp. 31-40
-
-
Zava, D.T.1
Duwe, G.2
-
481
-
-
0013676223
-
Differential effects of pKI H-7 on activation of human MDR1 promoter
-
481. Sato S, Kohno K, Izumi H, et al. Differential effects of pKI H-7 on activation of human MDR1 promoter. Cell Pharmacol 1995; 2: 153-7
-
(1995)
Cell Pharmacol
, vol.2
, pp. 153-157
-
-
Sato, S.1
Kohno, K.2
Izumi, H.3
-
482
-
-
0030800330
-
Inhibitors of both nuclear factor-kappaB and activator protein-1 activation block the neoplastic transformation response
-
482. Li JJ, Westergaard C, Ghosh P, et al. Inhibitors of both nuclear factor-kappaB and activator protein-1 activation block the neoplastic transformation response. Cancer Res 1997; 57: 3569-76
-
(1997)
Cancer Res
, vol.57
, pp. 3569-3576
-
-
Li, J.J.1
Westergaard, C.2
Ghosh, P.3
-
483
-
-
12644268252
-
Sequence-specific antitumor activity of a phosphorothioate oligodeoxyribonucleotide targeted to human C-raf kinase supports an antisense mechanism of action in vivo
-
483. Monia BP, Sasmor H, Johnston JF, et al. Sequence-specific antitumor activity of a phosphorothioate oligodeoxyribonucleotide targeted to human C-raf kinase supports an antisense mechanism of action in vivo. Proc Natl Acad Sci U S A 1996; 93: 15481-4
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 15481-15484
-
-
Monia, B.P.1
Sasmor, H.2
Johnston, J.F.3
-
484
-
-
0029977448
-
Antitumor activity of a phosphorothioate antisense oligodeoxynucleotide targeted against C-raf kinase
-
484. Monia BP, Johnston JF, Geiger T, et al. Antitumor activity of a phosphorothioate antisense oligodeoxynucleotide targeted against C-raf kinase. Nat Med 1996; 2: 668-75
-
(1996)
Nat Med
, vol.2
, pp. 668-675
-
-
Monia, B.P.1
Johnston, J.F.2
Geiger, T.3
-
485
-
-
0029993339
-
Structural basis for specific and potency of a flavonoid inhibitor of human cdk2, a cell cycle kinase
-
485. Filgueira W, De Azevedo jr. Mueller-Dieckmann HJ, et al. Structural basis for specific and potency of a flavonoid inhibitor of human cdk2, a cell cycle kinase. Proc Natl Acad Sci U S A 1996; 93: 2735
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 2735
-
-
Filgueira, W.1
De Azevedo, Jr.2
Mueller-Dieckmann, H.J.3
-
486
-
-
0031931014
-
Inhibition of neointimal cell bcl-x expression induces apoptosis and regression of vascular disease
-
486. Pollman MJ, Hall JL, Mann MJ, et al. Inhibition of neointimal cell bcl-x expression induces apoptosis and regression of vascular disease. Nature Med 1998; 4: 222-7
-
(1998)
Nature Med
, vol.4
, pp. 222-227
-
-
Pollman, M.J.1
Hall, J.L.2
Mann, M.J.3
-
487
-
-
0013656653
-
The human tumor clonogenic assay for the prediction of tumor sensitivity
-
Beger HG, Büchler M, Reisfeld RA, et al., editors. Berlin: Springer Verlag
-
487. Kraemer HP, Sedlacek HH. The human tumor clonogenic assay for the prediction of tumor sensitivity. In: Beger HG, Büchler M, Reisfeld RA, et al., editors. Cancer therapy. Berlin: Springer Verlag, 1989: 244-7
-
(1989)
Cancer Therapy
, pp. 244-247
-
-
Kraemer, H.P.1
Sedlacek, H.H.2
-
488
-
-
0032503010
-
Metabolism of the anticancer drug flavopiridol, a new inhibitor of cyclin dependent kinases, in rat liver
-
488. Jäger W, Zembsch B, Wolschann P, et al. Metabolism of the anticancer drug flavopiridol, a new inhibitor of cyclin dependent kinases, in rat liver. Life Sci 1998; 62: 1861-73
-
(1998)
Life Sci
, vol.62
, pp. 1861-1873
-
-
Jäger, W.1
Zembsch, B.2
Wolschann, P.3
|