Role of Streptococcus pneumoniae and Haemophilus influenzae in the development of acute otitis media and otitis media with effusion in a gerbil model

Journal of Infectious Diseases

Volumn 181, Issue 2, 2000, Pages 646-652

  Soriano, Francisco ^a   Parra, Araceli ^a   Cenjor, Carlos ^a   Nieto, Eva ^a   García Calvo, Gloria ^a   Giménez, Maria J ^b   Aguilar, Lorenzo ^b   Ponte, Carmen ^a  

^a Hospital UniversitarioFundación Jiménez Díaz   (Spain)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN PLUS CLAVULANIC ACID; CEFUROXIME;

ACUTE DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOTIC THERAPY; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; GERBIL; HAEMOPHILUS INFLUENZAE; NONHUMAN; OTITIS MEDIA; PRIORITY JOURNAL; SECRETORY OTITIS MEDIA; STREPTOCOCCUS INFECTION; STREPTOCOCCUS PNEUMONIAE;

ACUTE DISEASE; AMOXICILLIN-POTASSIUM CLAVULANATE COMBINATION; ANIMALS; CEFUROXIME; CEPHALOSPORINS; COLONY COUNT, MICROBIAL; DISEASE MODELS, ANIMAL; DRUG THERAPY, COMBINATION; FEMALE; GERBILLINAE; HAEMOPHILUS INFECTIONS; HAEMOPHILUS INFLUENZAE; HUMANS; MICROBIAL SENSITIVITY TESTS; OTITIS MEDIA; OTITIS MEDIA WITH EFFUSION; PNEUMOCOCCAL INFECTIONS; STREPTOCOCCUS PNEUMONIAE;

EID: 0034048665     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/315237     Document Type: Article

References (36)

1. Jacobs MR, Dagan R, Appelbaum PC, Burch DJ. Prevalence of antimicrobial-resistant pathogens in middle ear fluid: multinational study of 917 children with acute otitis media. Antimicrob Agents Chemother 1998; 42:589-95.
2. Pichichero ME, Malinn S, Aronovitz G, et al. Cefprozil treatment of persistent and recurrent acute otitis media. Pediatr Infect Dis J 1997; 16:471-8.
3. Genhanno P, Nguyen L, Barry B, et al. Eradication by ceftriaxone of Streptococcus pneumoniae isolates with increased resistance to penicillin in cases of acute otitis media. Antimicrob Agents Chemother 1999; 43:16-20.
4. Dagan R, Abramson O, Leibovitz E, et al. Impaired bacteriologic response to oral cephalosporins in acute otitis media caused by pneumococci with intermediate resistance to penicillin. Pediatr Infect Dis J 1996; 15:980-5.
5. Berman S. Classification and criteria of otitis media. Clin Microbiol Infect 1997; 3(Suppl 3):S1-4.
6. Ripley-Petzoldt ML, Giebink GS, Juhn SK, Aeppli D, Tomasz A, Tuomanen E. The contribution of pneumococcal cell wall to the pathogenesis of experimental otitis media. J Infect Dis 1988; 157:245-55.
7. Grenier B. Decision-making in otitis media in children, part I: epidemiologic data and definitions for a reliable cost-effectiveness analysis. Clin Microbiol Infect 1997; 3(Suppl 3):S62-8.
8. Bluestone CD, Klein JO. Otitis media in infants and children. Philadelphia, PA: WB Saunders, 1988:2.
9. Bluestone CD. Otitis media: burning questions from clinical practice. Otolaryngol Head Neck Surg 1992; 106:2-4.
10. Giebink GS. The microbiology of otitis media. Pediatr Infect Dis J 1989; 8(Suppl 1):S18-20.
11. Rayner MG, Zhang Y, Gorry MC, et al. Evidence of bacterial metabolic activity in culture-negative otitis media with effusion. JAMA 1998; 279:296-9.
12. Matar GM, Sidani N, Fayad M, Hadi U. Two-step based assay for identification of bacterial etiology of otitis media with effusion in infected Lebanese children. J Clin Microbiol 1998; 36:1185-8.
13. Paradise JL. Short-course antimicrobial treatment for acute otitis media. JAMA 1997; 278:1640-2.
14. Van Buchem FL, Dunk JHM, Van't Hof MA. Therapy of acute otitis media: myringotomy, antibiotics or neither? A double-blind study in children. Lancet 1981; 2:883-7.
15. Appelman CLM, Bossen PC, Dunk JHM, van de Lisdonk EH, de Melker RA, van Weert HCPM. Dutch College of Family Doctors guideline: acute otitis media. Utrecht, The Netherlands: Dutch College of Family Doctors, 1990.
16. Castillo F, García-Perea A, Baquero Artigao F. Bacteriology of acute otitis media in Spain: A prospective study based on tympanocentesis. Pediatr Infect Dis J 1996; 15:541-3.
17. Faden H, Doern G, Wolf J, Blocker M. Antimicrobial susceptibility of nasopharyngeal isolates of potential pathogens recovered from infants before antibiotic therapy: implications for the management of otitis media. Pediatr Infect Dis J 1994; 13:609-12.
18. Latorre C, Muñoz C, Trujillo G, Juncosa T, Clarós P. Susceptibility of pneumococci isolated from middle ear effusions to antimicrobial agents commonly used in otitis media. J Antimicrob Chemother 1994; 33:186-7.
19. Ponte C, Cenjor C, Parra A, et al. Antimicrobial treatment of an experimental otitis media caused by a β-lactamase positive isolate of Haemophilus influenzae. J Antimicrob Chemother 1999; 44:85-90.
20. National Committee for Clinical Laboratory Standards (NCCLS). Methods for dilution antimicrobial susceptibility test for bacteria that grow aerobically [NCCLS publication no. M7-A4]. Villanova, PA: NCCLS, 1997.
21. National Committee for Clinical Laboratory Standards (NCCLS). Methods for determining bactericidal activity of antimicrobial agents [NCCLS tentative standard no. M26-T]. Villanova, PA: NCCLS, 1992.
22. Craig WA, Andes D. Pharmacokinetics and pharmacodynamics of antibiotics in otitis media. Pediatr Infect Dis J 1996; 15:255-9.
23. Greenblatt DJ, Koch-Wesser J. Clinical pharmacokinetics. N Engl J Med 1975; 293:702-5.
24. Bluestone CD. Current therapy for otitis media and criteria for evaluation of new antimicrobial agents. Clin Infect Dis 1992; 14(Suppl 2):S197-203.
25. Bluestone CD, Stephenson JS, Martin LM. Ten-year review of otitis media pathogens. Pediatr Infect Dis J 1992; 11(Suppl 8):S7-11.
26. Cenjor C, Ponte C, Parra A, et al. In vivo efficacies of amoxicillin and cefuroxime against penicillin-resistant Streptococcus pneumoniae in a gerbil model of acute otitis media. Antimicrob Agents Chemother 1998; 42:1361-4.
27. Barry B, Muffat-Joly M, Gehanno P, Pocidalo JJ. Effect of increased dosages of amoxicillin in the treatment of experimental middle ear otitis due to penicillin-resistant Streptococcus pneumoniae. Antimicrob Agents Chemother 1993; 37:1599-603.
28. Patel JA, Reisner B, Vizirinia N, et al. Bacteriologic failure of amoxicillin-clavulanate in treatment of acute otitis media caused by nontypeable Haemophilus influenzae. J Pediatr 1995; 126:799-806.
29. Kawana M, Kawana CH, Giebink GS. Penicillin treatment accelerates middle ear inflammation in experimental pneumococcal otitis media. Infect Immun 1992; 60:1908-12.
30. Dowell SF, Marcy SM, Phillips WR, Gerber MA, Schwartz B. Otitis media principles of judicious use of antimicrobial agents. Pediatrics 1998; 101(Suppl):S165-71
31. Van Hare GF, Shurin PA, Marchant CD, et al. Acute otitis media caused by Branhamella catarrhalis: biology and therapy. Rev Infect Dis 1987; 9:16-27.
32. Froom J, Culpepper L, Jacobs M, et al. Antimicrobials for acute otitis media? A review from the International Primary Care Network. BMJ 1997; 315:98-102.
33. Kozyrskyj AL, Hildes-Ripstein E, Longstaffe SE, et al. Treatment of acute otitis media with a shortened course of antibiotics. JAMA 1998; 279:1736-42.
34. Lundgren K, Ingvarsson L, Runderantz H. The concentration of penicillin-V in middle ear exudate. Int J Pediatr Otorhinolaryngol 1979; 1:93-6.
35. Paradise JL. Managing otitis media: a time for change. Pediatrics 1995; 96:712-5.
36. Jossart GH, Canafax DM, Erdmann GR, et al. Effect of Streptococcus pneumoniae and influenza A virus on middle ear antimicrobial pharmacokinetics in experimental otitis media. Pharm Res 1994; 11:860-4.