Ecbalium elaterium (squirting cucumber) - Remedy or poison?

Journal of Toxicology - Clinical Toxicology

Volumn 38, Issue 3, 2000, Pages 305-308

  Raikhlin Eisenkraft, Bianca ^b   Bentur, Yedidia ^a  

^a RAMBAM MEDICAL CENTER   (Israel)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTIHISTAMINIC AGENT; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; ECBALLIUM ELATERIUM EXTRACT; TRITERPENE DERIVATIVE;

ADULT; ARTICLE; CHILD; CLINICAL ARTICLE; CONJUNCTIVITIS; CORNEA EDEMA; CORNEA EROSION; DRUG INDICATION; DRUG INTOXICATION; DYSPHAGIA; DYSPNEA; FEMALE; HUMAN; LIVER CIRRHOSIS; MALE; MUCOSA INFLAMMATION; OXYGEN THERAPY; PHARYNX DISEASE; SINUSITIS; STEROID THERAPY; TRADITIONAL MEDICINE; VOMITING;

ADOLESCENT; ADULT; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CHILD; CHILD, PRESCHOOL; CONJUNCTIVITIS; CORNEAL EDEMA; CUCURBITACEAE; DEGLUTITION DISORDERS; DYSPNEA; FEMALE; HUMANS; LIVER CIRRHOSIS; MALE; MUCOUS MEMBRANE; PHYTOTHERAPY; PLANT EXTRACTS; POISONING; RETROSPECTIVE STUDIES; SINUSITIS; TRITERPENES; VOMITING;

CUCUMIS SATIVUS; ECBALIUM; ECBALIUM ELATERIUM; ECBALLIUM; ECBALLIUM ELATERIUM;

EID: 0034047112     PISSN: 07313810     EISSN: None     Source Type: Journal    
DOI: 10.1081/CLT-100100936     Document Type: Article

References (22)

1. Plitman U, Heyn C, Danin A, Shmida A. Pictorial Flora of Israel. Israel: Massada, 1983.
2. Sezik E, Yesilada E. Clinical effects of the fruit juice of Ecbalium elaterium in the treatment of sinusitis [letter]. J Toxicol Clin Toxicol 1995;33:381-382.
3. Sezik E. Ecbalium elaterium [author's reply]. J Toxicol Clin Toxicol 1995;33:383.
4. Sezik E. Research on a Turkish medicinal plant, Ecbalium elaterium. Khimiya Prirodnykh Soedinenii 1997;5: 698-699.
5. Dreisbach RH. Handbook of Poisoning, 10th ed., Los Altos, California: Lange Medical Publications, 1980.
6. Lewis WH, Elvin-Lewis MFP. Medical Botany, New York: Wiley and Sons, 1977.
7. Poisoning and Toxicology Handbook, 2nd ed., Laxi Hudson Co., American Pharmaceutical Association, 1996-97.
8. Yesilada E, Ustun O, Sezik E, Takaishi Y, Ono Y, Honda G. Inhibitory effects of Turkish folk remedies in inflammatory cytokines: Interleukin-1 alpha, interleukin-1 beta and tumor necrosis factor alpha. J Ethnopharmacol 1997; 58:59-73.
9. Vlachos P, Kanitsakis NN, Kokonas N. Fatal cardiac and renal failure due to Ecbalium elaterium (squirting cucumber). J Toxicol Clin Toxicol 1994;32:737-738.
10. Yesilada E, Tanaka S, Sezik E, Tabata M. Isolation of an anti-inflammatory principle from the fruit juice of Ecbalium elaterium. J Nat Prod 1988;51:504-508.
11. Popov DV, Voinova E, Naidenova EI, Kolarova-Pavlova IK, Dimitrova-Konaklieva SD. Antileukemic P-388 action of aqueous plant extracts. CR Acad Bulg 1988;41: 147-149.
12. Plouvier B, Trorin F, Deram R, De Coninck P, Baclet JL. Concombre d'ane (Ecbalium elaterium) une cause peu banale d'oedeme de Quincke. La Nouvelle Presse Medicale 1981;10:2590.
13. Yesilada E, Tanaka S, Tabata M, Sezik E. Anti-inflammatory effects of the fruit juice of Ecbalium elaterium on edemas in mice. Phytotherapy Research 1989;3:75-76.
14. Basaran AA, Yu TW, Plewa MJ, Anderson D. An investigation of some Turkish herbal medicines in Salmonella typhimurium and in the COMET assay in human lymphocytes. Teratog Carcinog Mutagen 1996;16:125-138.
15. Konopa J, Matuszkiewicz A, Hrabowska M, Onoszka K. Cucurbitacins, the cytotoxic and antitumor substances from Bryonia alba L. Part II: Biological studies. Arzneimittelforschung 1974;24:1741-1743.
16. Kupchan SM, Gray AH, Grove MD. Tumor inhibitors: XXIII. The cytotoxic principle of Marah oreganus H. J Med Chem 1967;10:337-340.
17. Witkowski A, Konopa J. Binding of the cytotoxic and antitumor terpenes, cucurbitacins, to glucocorticoid receptors in HeLa cells. Biochim Biophys Acta 1981;674: 246-255.
18. 3 cells by cucurbitacins, glucocorticoid-like cytotoxic triterpenes. Biochem Pharmacol 1984;33:995-1004.
19. Clarke ML, Harvey DG, Humphreys DJ. Veterinary Toxicology. 2nd ed. London: Bailliere Tindall, 1981.
20. Registry of Toxic Effects of Chemical Substances. Tomes CPS System, Englewood, Colorado: Micromedex Inc., 1999:39.
21. Ellenhorn MJ, Barceloux DG. Medical Toxicology-Diagnosis and Treatment of Human Poisoning, New York: Elsevier, 1988.
22. Morrison RT, Boyd RN. Organic Chemistry, 3rd ed. Boston: Allyn and Bacon, 1977.