Expression of survivin and Bcl-2 in the normal human endometrium

Molecular Human Reproduction

Volumn 6, Issue 6, 2000, Pages 529-534

  Konno, R ^a   Yamakawa, H ^a   Utsunomiya, H ^a   Ito, K ^a   Sato, S ^a   Yajima, A ^a  

^a TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Bcl 2; Endometrium; Immunohistochemistry; RT PCR; Survivin

Indexed keywords

PROTEIN BCL 2; SURVIVIN;

ADULT; APOPTOSIS; ARTICLE; ENDOMETRIUM CELL; EPITHELIUM CELL; FEMALE; FETUS DEVELOPMENT; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; NORMAL HUMAN; PRIORITY JOURNAL; PROGESTERONE BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCORING SYSTEM;

ADULT; ENDOMETRIUM; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MENSTRUAL CYCLE; MICROTUBULE-ASSOCIATED PROTEINS; MIDDLE AGED; NEOPLASM PROTEINS; PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; REFERENCE VALUES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 0034045610     PISSN: 13609947     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Altieri, D.C. (1995) Xa receptor EPR-1. FASEB J., 9, 860-865.
2. Ambrosini, G., Adida, C. and Altier, D.C. (1997) A novel-anti-apoptosis gene, Survivin, expressed in cancer and lymphoma. Nature Med., 3, 917-921.
3. Clem, R.J and Duckett, C.S. (1997) The IAP genes - unique arbitrators of cell death. Trend Cell Biol., 7, 337-339.
4. Deveraux, Q.L. Takahashi, R., Slavesen, G.S. and Reed, J. (1997) X-linked IAP is a direct inhibitor of cell-death proteases. Nature, 388, 300-304.
5. Fengzhi, L., Ambrosini, G., Chu, E.Y. et al (1998) Control of apoptosis and mitotic spindle checkpoint by Survivin. Nature, 396, 580-584.
6. Gompel, A., Sabourin, J.C., Martin, A. et al. (1994) Bcl-2 expression in normal endometrium during the menstrual cycle. Am. J. Pathol., 144, 1195-1202.
7. Hopwood, D. and Levison, D. (1975) Atrophy and apoptosis in the cyclical human endometrium. J. Pathol., 119, 159-166.
8. Jones, R.K. Searle, R.F. Stewart, J.A. et al. (1998) Apoptosis, bcl-2 expression, and proliferative activity in human endometrial stroma and endometrial granulated lymphocytes. Biol. Reprod., 58, 995-1002.
9. Koh, E.A., Illingworth, P.J., Duncan, W.C. and Critchley, H.O. (1995) Immunolocalization of bcl-2 protein in human endometrium in the menstrual cycle and simulated early pregnancy. Hum. Reprod., 10, 1557-1562.
10. Kokawa, J., Shikone, T. and Nakano, R. (1996) Apoptosis in the human uterine endometrium during the menstrual cycle. J. Clin. Endocrinol. Metab., 81, 4111-4147.
11. Konno, R., Igarashi, T., Okamoto, S. et al. (1999) Apoptosis of human endometrium mediated by perforin and granzyme B of NK cells and cytotoxic T lymphocytes. Tohoku J. Exp. Med., 187, 149-155.
12. LeBurn, D.P., Warnke, R.A. and Cleary, M.L. (1993) Expression of Bcl-2 in fetal tissue sugests a role in morphogenesis. Am. J. Pathol., 142, 743-753.
13. Lu, C.D., Altieri, D.C. and Tanigawa, N. (1998) Expression of a novel antiapoptosis gene, Survivin, correlated with tumor cell apoptosis and p53 accumulation in gastric carcinomas. Cancer Res., 58, 1808-1812.
14. Nagata, S. (1997) Apoptosis by death factor. Cell, 88, 355-365.
15. Noyes, R., Hertig, A. and Rock, J. (1950) Dating the endometrial biopsy. Fertil Steril., 1, 3-25.
16. Otsuki, Y., Misaki, O., Sugimoto, O. et al. (1994) Cyclic bcl-2 gene expression in human uterine endometrium during menstrual cycle. Lancet, 344, 28-29.
17. Saitoh, Y., Yaginuma, Y. and Ishikawa, M. (1999) Analysis of Bcl-2, Bax and Survinin genes in uterine cancer. Int. J. Oncol., 15, 137-141.
18. Speroff, L. and Vande Wiele, R. (1971) Regulation of the human menstrual cycle. Am. J. Obstet. Gynecol., 109, 234-247.
19. Tabibzadeh, S., Zupi, E., Babaknia, A. et al. (1995) Site and menstrual cycle-dependent expression of proteins of the tumour necrosis factor (TNF) receptor family, and BCL-2 oncoprotein and phase-specific production of TNF-α in human endometrium. Hum. Reprod., 10, 277-86.
20. Tamm, I., Wang, Y., Sausville, E. et al. (1998) IAP-family protein Survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, Caspases, and anticancer drugs. Cancer Res., 58, 5315-5320.
21. Thompson, C.B. (1995) Apoptosis in the pathogenesis and treatment of disease. Science, 267, 1456-1462.
22. Vaux, D.L., Haecker, G. and Strasser, A. (1994) An evolutionary perspective on apoptosis. Cell, 76, 777-779.