Ten years' experience of antenatal mean corpuscular volume screening and prenatal diagnosis for thalassaemias in Hong Kong

Journal of Obstetrics and Gynaecology Research

Volumn 26, Issue 3, 2000, Pages 203-208

  Sin, Sai Yuen ^a   Ghosh, A ^a   Tang, L C H ^a   Chan, V ^b  

^a KWONG WAH HOSPITAL   (Hong Kong)

^b QUEEN MARY HOSPITAL   (Hong Kong)

Author keywords

Antenatal MCV screening; Thalassaemia

Indexed keywords

ARTICLE; FEMALE; HEMOGLOBINOPATHY; HIGH RISK PREGNANCY; HONG KONG; HUMAN; IRON DEFICIENCY; MAJOR CLINICAL STUDY; MEAN CORPUSCULAR VOLUME; PRENATAL DIAGNOSIS; PRENATAL SCREENING; PREVALENCE; THALASSEMIA;

EID: 0034045394     PISSN: 13418076     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1447-0756.2000.tb01312.x     Document Type: Article

References (31)

1. Beaudry MA, Ferguson DJ, Pearse K, Yanofsky RA, Rubin EM, Kan YW. Survival of a hydropic infant with homozygous α-thalassaemia. J Pediatr 1986; 108: 713-716
2. Bianchi DW, Beyer EC, Stark AR, Saffan D, Sachs BP, Wolfe L. Normal long-term survival with α-thalassaemia. J Pediatr 1986; 108, 716-718
3. Lam TK, Chan V, Fok TF, Li CK, Feng CS. Long-term survival of a baby with homozygous alpha-thalassaemia-1. Acta Haematol 1992; 88: 198-200
4. Carr S, Rubin L, Dixon D, Star J, Dailey J. Intrauterine therapy for homozygous α-thalassaemia. Obstet Gynecol 1995; 85: 876-879
5. Abuelo DN, Forman EN, Rubin LP. Limb defects and congenital anomalies of the genitalia in an infant with homozygous α-thalassaemia. Am J Med Genet 1997; 68: 158-161
6. Lie-Injo LE, Solai A, Herrera AR, Nicolaisen L, Kan YW, Wan WP, Hasan K. Hb Bart's level in cord blood and deletions of alpha-globin genes. Blood 1982; 59: 370-376
7. Lie-Injo LE. Distribution of genetic red cell defects in South-East Asia. Trans R Soc Trop Med Hyg 1969; 63: 664
8. Weatherall DJ, Clegg JB. The thalassaemia syndromes. 3rd ed, Oxford: Blackwell Scientific, 1981
9. Liang ST, Wong VCW, So WWK, Ma HK, Chan V, Todd D. Homozygous alpha-thalassaemia: Clinical presentaiton, diagnosis and management. A review of 46 cases. Br J Obstet Gynaecol 1985; 92: 680-684
10. Li AMC. Haematological findings in Hong Kong Chinese with beta thalassaemia trait. J Hong Kong Med Assoc 1990; 42: 3
11. Ghosh A, Woo JSK, Wan CW, MacHenry C, Wong V, Ma HK, Chan V, Chan TK. Evaluation of a prenatal screening procedure for betathalassaemia carriers in a Chinese population based on the mean corpuscular volume (MCV). Prenat Diagn 1985; 5: 59-65
12. Chan V, Chan TK, Cheng MY, Kan YW, Todd D. Organization of the zeta-alpha genes in Chinese. Br J Haematol 1986; 64: 97-105
13. Chan V, Ghosh A, Chan TK, Wong V, Todd D. Prenatal diagnosis of homozygous alpha-thalassaemia by direct DNA analysis of uncultured amniotic fluid cells - a preliminary experience. Br Med J 1984; 288: 1327-1329
14. Ghosh A, Woo JSK, Liang ST, Ho HC, Wong V. Ultrasonic diagnosis of hydrops fetalis in the early second trimester. Aust NZ J Obstet Gynaecol 1983; 23: 108-109
15. Ghosh A, Tang MHY, Liang ST, Ma HK. Ultrasound evaluation of pregnancies at risk of homozygous alpha-thalassaemia-1. Prenat Diagn 1987; 7: 307-313
16. Chan TK, Chan V. Molecular genetics and prenatal diagnosis of common inherited disease. CME Review. National Univ Hospital 1991; 1: 67-77
17. Chehab FF. Molecular diagnostics: Past, present and future. Hum Mutat 1993; 2: 331-337
18. Chan V, Chan TK, Todd D, Ghosh A, Wong LC, Ma HK. Prenatal diagnosis of alpha- and beta-thalassaemia: Experience in Hong Kong. Haemoglobin 1988; 12: 787-794
19. Lau YL, Chan LC, Chan YYA, Ha SY, Yeung CY, Waye JS, Chui DHK. Prevalence and genotypes of α- and β-thalassaemia carriers in Hong Kong -implications for population screening. New Eng J Med 1997; 336: 1298-1301
20. Stein J, Berg C, Jones JA, Detter JC. A screening protocol for a prenatal population at risk for hemoglobin disorders: Results of its application to a group of Southeast Asians and blacks. Am J Obstet Gynecol 1984; 150: 333
21. Alger LS, Globus MS, Laros RK. Thalassaemia and pregnancy: Result of an antenatal screening program. Am J Obstet Gynecol 1979; 134: 662-673
22. Jones JA, et al. An imporved method for detection of red cell hemoglobin H inclusions. Am J Med Technol 1981; 47: 94
23. Li AMC, Lee FT, Todd D. The screening of Chinese cord blood for Haemoglobinopathies. Hum Heredity 1982; 32: 62-70
24. Bain BJ. Screening of antenatal patients in a multiethnic community for β-thalassaemia trait. J Clin Pathol 1988; 41: 481-485
25. Rogers M, Phelan L, Bain B. Screening criteria for β-thalassaemia trait in pregnant women. J Clin Pathol 1995; 48: 1054-1056
26. Chang MC, Goldberg JD, Kan YW. Prenatal diagnosis of sickle cell anaemia and thalassaemia by analysis of fetal cells in maternal blood. Nature Genetics 1996; 14: 264-268
27. Chan V, Yip B, Lau K, Chan TK. A semi-automated allele specific PCR for detection of β thalassaemia mutations. 26th Congress International Society of Hematology, S78, 1996
28. Tutschek B, Sherlock J, Halder A, Delhanty J, Rodeck C, Adinolfi M. Isolation of fetal cells from transcervical samples by micromanipulation: Molecular confirmation of their fetal origin and diagnosis of fetal aneuploidy. Prenat Diagn 1995; 15: 951-960
29. Ghosh A, Tang MHY, Lam YH, Fung E, Chan V. Ultrasound measurement of placental thickness to detect pregnancies affected by homozygous α-thalassaemia-1. Lancet 1994; 344: 988-989
30. Ko TM, Tseng LH, Hsu PM, Hwa HL, Lee TY, Chuang SM. Ultrasonographic scanning of placental thickness and the prenatal diagnosis of homozygous α-thalassaemia-1 in the second trimester. Prenat Diagn 1995; 15: 7-10
31. Lam YH, Ghosh A, Tang MHY, Lee CP, Sin SY. Early ultrasound prediction of pregnancies affected by homozygous α-thalassaemia-1. Prenat Diagn 1997; 17: 327-332