A novel class of aromatic vitamin D analogs

Current Pharmaceutical Design

Volumn 6, Issue 7, 2000, Pages 749-754

  Rodriguez, David Soilan ^b   Kanzler, Silvia ^b   Zorgdrager, Jan ^a   Halkes, Sebastian ^a   Van De Velde, Jan Paul ^a   Reischl, Wolfgang ^b  

^a Solvay Pharmaceuticals Inc   (Netherlands)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC COMPOUND; CALCITRIOL DERIVATIVE; RETINOID X RECEPTOR; VITAMIN D DERIVATIVE; VITAMIN D RECEPTOR;

BINDING AFFINITY; CANCER; DNA RESPONSIVE ELEMENT; DRUG CONFORMATION; DRUG DESIGN; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; IMMUNOPATHOLOGY; MOLECULAR MODEL; OSTEOPOROSIS; PRIORITY JOURNAL; PSORIASIS; REVIEW;

EID: 0034044572     PISSN: 13816128     EISSN: None     Source Type: Journal    
DOI: 10.2174/1381612003400344     Document Type: Review

References (22)

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22. During the preparation of this manuscript the x-ray structure of a mutant VDR ligand binding domain complexed with calcitriol has been published: Rochel, N.; Wurtz, J. M.; Mitschler, A.; Klaholz, B.; Moras, D. Molecular Cell, 2000, 5, 173. This paper appeared too late to be included in a discussion of structural features relevant for binding of the various aromatic vitamin D analogs to the VDR.