Prooligonucleotides exhibit less serum-protein binding than phosphodiester and phosphorothioate oligonucleotides

Nucleosides, Nucleotides and Nucleic Acids

Volumn 19, Issue 5-6, 2000, Pages 995-1003

  Tosquellas, Guilhem ^a   Bryksin, Anton ^b   Alvarez, Karine ^a   Morvan, François ^a   Vasseur, Jean Jacques ^a   Rayner, Bernard ^a   Rykova, Elena ^b   Laktionov, Pavel ^b   Vlassov, Valentin ^b   Imbach, Jean Louis ^a  

^a UNIV MONTPELLIER   (France)

^b INSTITUTE OF CHEMICAL BIOLOGY AND FUNDAMENTAL MEDICINE   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

LACTOFERRIN; NUCLEASE; OLIGONUCLEOTIDE; PHOSPHOROTHIOIC ACID DERIVATIVE; PLASMA PROTEIN; THYMIDINE DERIVATIVE;

ARTICLE; BINDING KINETICS; CONTROLLED STUDY; DISSOCIATION CONSTANT; DRUG DESIGN; DRUG PENETRATION; DRUG PROTEIN BINDING; DRUG STRUCTURE;

EID: 0034043277     PISSN: 15257770     EISSN: None     Source Type: Journal    
DOI: 10.1080/15257770008033038     Document Type: Article

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