Paraneoplastic cerebellar degeneration as the first evidence of cancer: A case report

Archives of Physical Medicine and Rehabilitation

Volumn 81, Issue 6, 2000, Pages 834-836

  Liu, Su ^a,c   Tunkel, Richard ^b   Lachmann, Elisabeth ^a   Nagler, Willibald ^a  

^a NEW YORK PRESBYTERIAN HOSPITAL   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^c Apt 21C ^*  (United States)

Author keywords

Paraneoplastic cerebellar degeneration; Paraneoplastic syndromes; Rehabilitation

Indexed keywords

CA 125 ANTIGEN;

ADULT; ANTIBODY DETECTION; ARTICLE; CASE REPORT; CEREBELLUM DEGENERATION; CLINICAL EXAMINATION; FEMALE; HUMAN; IMMUNOPATHOGENESIS; LAPAROTOMY; OVARY CARCINOMA; PARANEOPLASTIC SYNDROME;

EID: 0034041837     PISSN: 00039993     EISSN: None     Source Type: Journal    
DOI: 10.1053/apmr.2000.6979     Document Type: Article

References (23)

1. Posner JB, Furneaux HM. Paraneoplastic syndromes. Immunologic mechanisms. In: Waksman BH, editor. Neurologic and psychiatric disease. New York: Raven Press; 1990. p. 187-219.
2. Posner JB. Paraneoplastic syndromes. Neurologic complications of systemic cancer. Neurol Clin 1991;9:919-36.
3. Brain WR, Norris F Jr. The remote effects of cancer on the nervous system. New York: Grune & Stratton; 1965.
4. Henson RA, Urich H. Cancer and the nervous system. Oxford: Blackwell Scientific; 1982.
5. Brain L, Wilkinson M. Subacute cerebellar degeneration associated with neoplasms. Brain 1965;88:465-78.
6. Posner JB. Neurologic complications of cancer. Philadelphia: F. A. Davis; 1995.
7. Hammack JE, Kimmel DW, O'Neo BP, Lennon VA. Paraneoplastic cerebellar degeneration: a clinical comparison of patients with and without Purkinje cell cytoplasmic antibodies. Mayo Clin Proc 1990;65:1423-31.
8. Dalmau J, Furneaux Hm, Cordon-Cardo C, Posner JB. The expression of the Hu (paraneoplastic encephalomyelitis/sensory neuronopathy) antigen in human normal and tumor tissues. Am J Pathol 1992;141:881-6.
9. Mason WP, Dalmau J, Curtin JP, Posner JB. Normalization of the tumor marker CA-125 after oophorectomy in patient with paraneoplastic cerebellar degeneration without detectable cancer. Gynecol Oncol 1997;65:173-6.
10. Peterson K, Rosenblum MK, Kotanides H, Posner JB. Paraneoplastic cerebellar degeneration. I. A clinical analysis of 55 anti-Yo antibody positive patients. Neurology 1992;42:1931-7.
11. Hetzel DJ, Stanhope CR, O'Neill BP, Lennon VA. Gynecologic cancer in patients with subacute cerebellar degeneration predicted by anti-Purkinje cell antibodies and limited in metastatic volume. Mayo Clin Proc 1990;65:1558-63.
12. Verschuuren J, Chuang L, Rosenblum MK, Lieberman F, Pryor A, Posner JB, et al. Inflammatory infiltrates and complete absence of Purkinje cells in anti-Yo-associated paraneoplastic cerebellar degeneration. Acta Neuropathol (Berl) 1996;91:519-25.
13. Graus F, Elkon KB, Lloberes P, Ribalta T, Torres A, Ussetti P, et al. Neuronal antinuclear antibody (anti-Hu) in paraneoplastic encephalomyelitis simulating acute polyneuritis. Acta Neurol Scand 1987; 75:249-52.
14. Anderson NE, Rosenblum MK, Graus F, Wiley RG, Posner JB. Antibodies in paraneoplastic syndromes associated with small cell lung cancer. Neurology 1988;38:1391-8.
15. Clouston PD, Saper CB, Arbizu T, Johnston I, Lang B, Newsom-Davis J, et al. Paraneoplastic cerebellar degeneration. III. Cerebellar degeneration, cancer, and the Lambert-Eaton myasthenic syndrome. Neurology 1992;42:1944-50.
16. Motomura M, Johnston I, Lang B, Vincent A, Newsom-Davis J. An improved diagnostic assay for Lambert-Eaton myasthenic syndrome. J Neurol Neurosurg Psychiatry 1995;58:85-7.
17. Dropcho EJ, Chen YT, Posner JB, Old LJ. Cloning of a brain protein identified by autoantibodies from a patient with paraneoplastic cerebellar degeneration. Proc Natl Acad Sci U S A 1987;84:1-5.
18. Fathallah-Shaykh H, Wolf S, Wong E, Posner JB, Furneaux HM. Cloning of a leucine-zipper protein recognized by the sera of patients with antibody-associated paraneoplastic cerebellar degeneration. Proc Natl Acad Sci U S A 1991;88:3451-4.
19. David YB, Warner E, Levitan M, Sutton DM, Malkin MG, Dalmau JO. Autoimmune paraneoplastic cerebellar degeneration in ovarian carcinoma patients treated with plasmapheresis and immunoglobulin. A case report. Cancer 1996;78:2153-6.
20. Sliwa JA, Thatcher S, Jet J. Paraneoplastic subacute cerebellar degeneration: functional improvement and the role of rehabilitation. Arch Phys Med Rehabil 1994;75:355-7.
21. Hall D, Dyer ML, Parker JC. Ovarian cancer complicated by cerebellar degeneration: a paraneoplastic syndrome. Gynecol Oncol 1985;21:240-6.
22. Roberts HJV. A case of spino-cerebellar degeneration associated with carcinoma of the prostate. Med J Aust 1967;1:391-3.
23. Steven MM, Mackay IR, Carnegie PR, Bhathal PS, Anderson RM. Cerebellar cortical degeneration with ovarian carcinoma. Postgrad Med J 1982;58:47-51.