A study on arsenic trioxide inducing in vitro apoptosis of gastric cancer cell lines

World Journal of Gastroenterology

Volumn 6, Issue 3, 2000, Pages 435-437

  Gu, Qin Long ^a,c,d   Li, Ning Li ^b   Zhu, Zheng Gang ^a   Yin, Hao Ran ^a   Lin, Yan Zhen ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b Shanghai Immunology Institute   (China)

^c BENGBU MEDICAL COLLEGE   (China)

^d Shanghai Institute of Digestive Surgery   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ARSENIC TRIOXIDE;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFECT; HUMAN; HUMAN CELL; PATHOLOGY; STOMACH CANCER;

EID: 0034041391     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v6.i3.435     Document Type: Article

References (11)

1. Song Q, Baxter GD, Kovacs EM, Findik D, Lavin MF. Inhibition of apoptosis in human tumour cells by okadaic acid. J Cell Physiol , 1992;153:550-556
2. Li NL, Shen BH, Zheng ZX, Zhou GY. Detection of DNA strand breaks in drug induced apoptosis of HL-60 and U973 cells by in situ terminal deoxynucleotidyl transferase. Zhongliu , 1996;16:391-393
3. Lauwers GY, Scott GV, Karpeh MS. Immuno-histochemical evaluation of bcl-2 protein expression in gastric adenocarcinomas. Cancer , 1995;75:2209-2213
4. Hockenbery D, Nunez G, Milliman C, Schreiber RD, Korsmeyer SJ. Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature , 1990;348:334-336
5. Sachs L, Lotem J. Control of programmed cell death in normal and leukemic cells: new implications for therapy. Blood , 1993;82:15-21
6. Vollmers HP, Dammrich J, Ribbert H, Wozniak E, Muller Hermelink HK. Apoptosis of stomach carcinoma-Hermelink by a human monoclonal antibody. Cancer , 1995;76:550-558
7. Dong JT, Luo XM. Effects of arsenic on DNA damage and repair in human fetal lung fibroblasts. Mutat Res , 1994;315:11-15
8. Zhang P, Wang SY, Hu LH, Shi FD, Qiu FQ, Hong LJ, Han XY, Yang HF, Song YZ, Liu YP, Zhou J, Jin ZJ. Treatment of acute promyelocytic leukemia with intravenous arsenic trioxide. Zhonghua Xueyexue Zazhi , 1996;17:58-60
9. 4 cell apoptosis with down regulation of bcl-2 expression and modulation of PML-RARα/PML proteins. Blood , 1996;88:1052-1061
10. 4. Aizheng , 1999;18:1-4
11. Zhang W, Ohnishi K, Shigeno K, Fujisawa S, Naito K, Nakamura S, Takeshia K, Takeshita A, Ohno R. The induction of apoptosis and cell cycle arrest by arsenic trioxide in lymphoid neoplasms. Leukemia , 1998;12:1383-1391