Overestimation of hemoglobin in a patient with an IgA-κ monoclonal gammopathy

Archives of Pathology and Laboratory Medicine

Volumn 124, Issue 4, 2000, Pages 616-618

  Roberts, William L ^a,b   Fontenot, Jo D ^a   Lehman, Christopher M ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b ARUP LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN; IMMUNOGLOBULIN A; PARAPROTEIN;

AGED; ARTICLE; AUTOANALYSIS; CAPILLARY ZONE ELECTROPHORESIS; CASE REPORT; FEMALE; GAMMOPATHY; HEMATOCRIT; HEMATOLOGICAL PARAMETERS; HEMOGLOBIN DETERMINATION; HUMAN; MEAN CORPUSCULAR HEMOGLOBIN; MONOCLONAL IMMUNOGLOBULINEMIA;

AGED; AUTOANALYSIS; BLOOD PROTEINS; ELECTROPHORESIS, CAPILLARY; ERYTHROCYTE COUNT; FEMALE; HEMATOCRIT; HEMOGLOBINS; HUMANS; IMMUNOGLOBULIN A; IMMUNOGLOBULIN KAPPA-CHAINS; LEUKOCYTE COUNT; MULTIPLE MYELOMA; PLATELET COUNT; REPRODUCIBILITY OF RESULTS;

EID: 0034040581     PISSN: 00039985     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. Hullin DA. An IgM paraprotein causing a falsely low result in an enzymatic assay for acetaminophen. Clin Chem. 1999;45:155-156.
2. Yamada K, Yagihashi A, Ishii S, et al. Interference with nephelometric assay of C-reactive protein and antistreptolysin-O by monoclonal IgM-κ from myeloma patient. Clin Chem. 1997;43:2435-2437.
3. Schwartz JG, Medina RA. Falsely elevated values for chloride in serum containing myeloma proteins, measured in the Raramax. Clin Chem. 1988;34:771.
4. Datta P, Graham GA, Schoen I. Interference by IgG paraproteins in the Jaffe method for creatinine determination. Am J Clin Pathol. 1986;85:463-468.
5. Bakker AJ. Influence of monoclonal immunoglobulins in direct determinations of iron in serum. Clin Chem. 1991;37:690-694.
6. Zaman Z, Sneyers L, Orshoven AV, Blanckaert N, Marien G. Elimination of paraprotein interference in determination of plasma inorganic phosphate by ammonium molybdate method. Clin Chem. 1995;41:609-614.
7. Ladenson JH, Apple FS, Aguanno JJ, Koch DD. Sodium measurements in multiple myeloma: two techniques compared. Clin Chem. 1982;28:2383-2386.
8. Alexander NM, Gattra R, Nishimoto M. Myeloma immunoglobulin interferes with serum thyroxine analysis by homogeneous enzyme immunoassay. Clin Chim Acta. 1980;100:301-305.
9. Whitlow KJ, Nanji AA, Pudek MR. Artefactual decrease in total protein concentration in patients with monoclonal gammopathies: a method-dependent error. Clin Biochem. 1984;17:233-235.
10. Smith JD, Nobiletti I, Freed M, Malkus H, Donabedian R. Interference with the Astra 8 and Synchron CX3 assays of urea nitrogen in serum by a high-M(r) inhibitor in a patient with multiple myeloma. Clin Chem. 1992;38:598-599.
11. Gelinsky P, Braun HJ, Bohner J, Schoeler M. Faulty haemoglobin values in Sia-positive Waldenstrom's macroglobulinemia. Dtsch Med Wochenschr. 1974;99:283-286.
12. Wallis JP, Ford JM. Incorrect haemoglobin estimation on the Coulter S+IV in some patients with IgM paraproteins. Clin Lab Haematol. 1987;9:95-96.
13. Goodrick MJ, Boon RJ, Bishop RJD, Copplestone JA, Prentice AG. Inaccurate haemoglobin estimation in Waldenstrom's macroglobulinaemia: unusual reaction with monomeric IgM paraprotein. J Clin Pathol. 1993;46:1138-1139.
14. Malin MJ, Sclafani LD, Wyatt JL Evaluation of 24-second cyanide-containing and cyanide-free methods for whole blood hemoglobin on theTechnicon H*I™ analyzer with normal and abnormal blood samples. Am J Clin Pathol. 1989;92:286-294.
15. McMullin MF, Wilkin HJ, Elder E. Inaccurate haemoglobin estimation in Waldenstrom's macroglobulinemia. J Clin Pathol. 1995;48:787.
16. Roberts-Thomson PJ, Mason DY, MacLennan IC. Relationship between paraprotein polymerization and clinical features in IgA myeloma. Br J Haematol. 1976;33:117-130.
17. Gonzalez GJB, Garcia DR, Camara SE, Ortiz MF. Isotypic characterization of IgA paraproteins: association with other clinical and analytic data. Rev Clin Esp. 1996;196:529-535.