Effect of season on neuropeptide Y and galanin within the hypothalamus of the ewe in relation to plasma luteinizing hormone concentrations and the breeding season: An immunohistochemical analysis

Journal of Neuroendocrinology

Volumn 12, Issue 7, 2000, Pages 618-626

  Barker Gibb, M L ^a,b   Clarke, Iain J ^a  

^a HUDSON INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Gonadotropin releasing hormone; Luteinizing hormone; Oestrogen feedback

Indexed keywords

ESTROGEN; GALANIN; GONADORELIN; LUTEINIZING HORMONE; NEUROPEPTIDE Y;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARCUATE NUCLEUS; ARTICLE; BLOOD SAMPLING; BREEDING; CONTROLLED STUDY; FEEDBACK SYSTEM; FEMALE; HYPOTHALAMUS; IMMUNOHISTOCHEMISTRY; LUTEINIZING HORMONE BLOOD LEVEL; LUTEINIZING HORMONE RELEASE; NEGATIVE FEEDBACK; NONHUMAN; OVARIECTOMY; PHOTOPERIODICITY; PRIORITY JOURNAL; PULSATILE HORMONE RELEASE; SEASONAL VARIATION; SHEEP;

ANIMALS; CELL COUNT; ESTRADIOL; FEMALE; GALANIN; HYPOTHALAMUS; IMMUNOHISTOCHEMISTRY; LUTEINIZING HORMONE; NERVE ENDINGS; NEURONS; NEUROPEPTIDE Y; OSMOLAR CONCENTRATION; REPRODUCTION; SEASONS; SHEEP; TISSUE DISTRIBUTION;

EID: 0034039523     PISSN: 09538194     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2826.2000.00514.x     Document Type: Article

References (52)

1. Barrell GK, Moenter SM, Caraty A, Karsch FJ. Seasonal changes of gonadotropin-releasing hormone secretion in the ewe. Biol Reprod 1992; 46: 1130-1135.
2. Karsch FJ, Bittman EL, Foster DL, Goodman RL, Legan SJ, Robinson JE. Neuroendocrine basis of seasonal breeding. Rec Progr Horm Res 1984; 40: 185-231.
3. Clarke IJ, Cummins JT. The temporal relationship between gonadotropin-releasing hormone (GnRH) and luteinizing hormone (LH) secretion in ovariectomized ewes. Endocrinology 1982; 111: 1737-1739.
4. Robinson JE, Radford HM, Karsch FJ. Seasonal changes in pulsatile luteinising hormone (LH) secretion in the ewe: relationship of frequency of LH pulses to daylength and response to estradiol negative feedback. Biol Reprod 1985; 33: 324-334.
5. Legan SJ, Karsch FJ, Foster DL. The endocrine control of seasonal reproductive function in the ewe: a marked change in response to the negative feedback action of estradiol on luteinizing hormone secretion. Endocrinology 1977; 101: 818-824.
6. Shivers BD, Harlan RE, Morrell RI, Pfaff DW. Absence of oestradiol concentration in cell nuclei of LHRH-immunoreactive neurones. Nature 1983; 304: 345-347.
7. Watson RE, Langlub MC, Landis JW. Further evidence that most luteinizing hormone-releasing hormones are not directly estrogen-responsive: simultaneous localization of luteinizing hormone-releasing hormone and estrogen receptor immunoreactivity in the guinea-pig brain. J Neuroendocrinol 1992; 4: 311-317.
8. Herbison AE. Neurochemical identity of neurones expressing oestrogen and androgen receptors in sheep hypothalamus. J Reprod Fert 1995; 49: 271-283.
9. Lehman MN, Karsch FJ. Do gonadotropin-releasing hormone, tyrosine hydroxylase-. and β-endorphin-immunoreactive neurons contain estrogen receptors? A double-label immunocytochemical study in the suffolk ewe. Endocrinology 1993; 133: 887-895.
10. Sar M, Sahu A, Crowley WR, Kalra SP. Localisation of Neuropeptide-Y immunoreactivity in estradiol-concentrating cells in the hypothalamus. Endocrinology 1990; 127: 2752-2756.
11. Skinner DC, Herbison AE. Effects of photoperiod on estrogen receptor. tyrosine hydroxylase, neuropeptide Y, and β-endorphin immunoreactivity in the ewe hypothalamus. Endocrinology 1997; 138: 2585-2595.
12. Coen CW, Montagnese C, Opacka-Juffry J. Coexistence of gonadotropin-releasing hormone and galanin: immunohistochemical and functional studies. J Neuroendocrinol 1990; 2: 107-111.
13. Merchenthaler I, Lopez FJ, Negro-Vilar A. Colocalisation of galanin and luteinizing hormone-releasing hormone in a subset of preoptic hypothalamic neurones: anatomical and functional correlates. Proc Natl Acad Sci USA 1990; 87: 6326-6330.
14. Bloch GJ, Gorski RA, Micevych PE, Akesson TR. Estrogen concentrating cells within the medial preoptic area: sex differences, colocalisation with galanin-immunoreativity (GAL-LI) cells. Program of the 19th Annual Meeting of the Society for Neuroscience, Phoenix, Arizona, 1989: 577.
15. Kalra SP. Mandatory neuropeptide-steroid signaling for the preovulatory luteinizing hormone-releasing hormone discharge. Endocr Rev 1993; 14: 507-538.
16. Kalra SP, Crowley WR, Neuropeptide Y. A novel neuroendocrine peptide in the control of pituitary hormone secretion, and its relation to luteinising hormone. Front Neuroendocrinology 1992; 3: 1-46.
17. Khorram O, Pau K-YF, Spies HG. Bimodal effects of neuropeptide Y on hypothalamic release of gonadotropin-releasing hormone release in conscious rabbits. Neuroendocrinology 1987; 45: 290-297.
18. Pau K-YF, Berria M, Hess DL, Spies HG. Hypothalamic site dependent effects of NPY on gonadotropin-releasing hormone secretion in rhesus macaques. J Neuroendocrinol 1995; 7: 63-67.
19. Woller MJ, Terasawa E. Infusion of neuropeptide Y into the stalk-median eminence stimulates in vivo release of luteinising hormone releasing hormone in gonadectomised rhesus monkeys. Endocrinology 1991; 128: 1144-1150..
20. Woller MJ, Terasawa E. Neuropeptide Y is a neuromodulator of pulsatile LHRH in the gonadectomised rhesus monkeys. Endocrinology 1992; 130: 2333-2342.
21. Malven PV, Haglof SA, Degroot H. Effects of intracerebral administration of neuropeptide Y on secretion of luteinising hormone in ovariectomised ewes. Brain Res Bull 1992; 28: 871-875.
22. McShane TM, May T, Miner JL, Keisler DH. Central actions of neuropeptide Y may provide a neuromodulatory link between nutrition and reproduction. Biol Reprod 1992; 46: 1151-1157.
23. Porter DW, Naylor AM, McNeilly AS, Lincoln DW. Endocrine actions of central neuropeptide Y in the ewe: actuation of the hypothalamo-pituitary-adrenal axis by exogenous neuropeptide Y and role of endogenous neuropeptide Y in the secretion of luteinising hormone during the oestrous cycle. J Neuroendocrinol 1993; 5: 163-174.
24. Barker-Gibb ML, Scott CJ, Boublik J, Clarke IJ. The role of NPY in the control of LH secretion in the OVX ewe with respect to season, NPY receptor subtype and site of action within the hypothalamus. J Endocrinol 1995; 147: 565-579.
25. Lopez FJ, Merchenthaler I, Liposits Z. Galanin: a hypothalamic, hypophysiotrophic hormone modulating reproductive function. Proc Natl Acad Sci USA 1991; 88: 4508-4512.
26. 4-NPY), galanin and neuropeptide K on LH release in ovariectomised (OVX) and OVX estrogen, progesterone-treated rats. Peptides 1987; 8: 921-926.
27. Rossmanith WG, Marks DL, Steiner RA, Clifton DK. Inhibition of steroid-induced galanin mRNA expression in GnRH neurons by specific NMDA blockade. J Neuroendocrinol 1996; 8: 179-184.
28. Tsuruo Y, Kawano H, Kagotani S, Hisano S Daikoku S, Chihara K. Zhang T, Yanaihara N. Morphological evidence for neuronal regulation of luteinising hormone-releasing hormone-containing neurones by neuropeptide Y in the rat septo-preoptic area. Neurosci Lett 1990; 110: 261-266.
29. Tillet Y, Caldani M, Batailler M. Anatomical relationships of monoaminergic and neuropeptide Y-containing fibres with luteinising hormone-releasing hormone systems in the preoptic area of the sheep brain: immunohistochemical studies. J Chem Neuroanat 1989; 2: 319-326.
30. Norgren RB, Lehman NM. A double label pre-embedding immunoperoxidase technique for electron microscopy using diaminobenzidine and tetramethylbenzidine as markers. J Histochem Cytochem 1989; 37: 1283-1289.
31. Karsch FJ, Dierschke DJ, Weick RF, Yamaji T, Hotchkiss J, Knobil E. Positive and negative feedback control by estrogen on luteinizing hormone secretion. Endocrinology 1973; 92: 799-804.
32. Christie MJ, Beart PM, Jarrott B, MacCarrone C. Distribution of neuropeptide Y immunoreactivity in the rat basal ganglia: effects of excitotoxin lesions to caudate-putamen. Neurosci Lett 1986; 63: 305-309.
33. Carey DG, Iisma TP, Ho KY, Rajkovic IA, Kelly J, Kraegen EW, Ferguson J, Inglis AS, Shine J, Chisholm DJ. Potent effects of human galanin in man: growth hormone secretion and vagal blockade. J Clin Endocrinol Metab 1993; 77: 90-93.
34. Barker-Gibb ML, Clarke IJ. Increased galanin and neuropeptide Y immunoreactivity within the hypothalamus of ovariectomised ewes following a prolonged period of reduced bodyweight is associated with changes in plasma growth hormone levels but not gonadotropin levels. Neuroendocrinology 1996; 64: 194-207.
35. Lee VWK, Cumming deKretser DM, Findlay JK, Hudson B, Keogh EJ. Regulation of gonadotrophin secretion in rams from birth to sexual maturity. 1. Plasma LH, FSH and testosterone levels. J Reprod Fert 1976; 46: 1-6.
36. Burger HG, Lee VWK, Rennie GC. A generalised computer program for the treatment of data from competitive protein-binding assays including radioimmunoassays. J Lab Clin Med 1972; 80: 302-312.
37. Antonopoulos J, Papadopoulous GC, Karamanlidis AN, Michaloudi H. Distribution of neuropeptides in the infundibular nucleus of the sheep. Neuropeptides 1989; 14: 121-128.
38. Merchenthaler I, Lopez FJ, Negro-Vilar A. Anatomy and physiology of central galanin-containing pathways. Prog Neurobiol 1993; 40: 711-769.
39. Thomas GB, Pearce DT, Oldham CM, Martin GB, Lindsay DR. Effects of breed, ovarian steroids and season on the pulsatile secretion of LH in ovariectomised ewes. J Reprod Fert 1988; 84: 313-324.
40. Goodman RL, Meyer SL. Effects of pentobarbital anesthesia on tonic luteinizing hormone secretion in the ewe: evidence for inhibition of luteinizing hormone in anestrus. Biol Reprod 1985; 30: 374-381.
41. Meyer SL, Goodman RL. Separate neural systems mediate the steroid-dependent and steroid-independent suppression of tonic luteinizing hormone secretion in the anestrous ewe. Biol Reprod 1986; 35: 562-571.
42. Lehman MN, Durham DM, Jansen HT, Adrian B, Goodman RL, Dopaminergic A 1996: 14/:15 neurons are ctivated during estradiol negative feeback in anestrous, but not breeding season, ewes. Endocrinology, 137: 4443-4450.
43. Beccavin C, Malpaux B, Tillet Y. Effect of oestradiol and photoperiod on TH mRNA concentrations in. A 1998; 15: and A12 dopamine cell groups in the ewe. J Neuroendocrinol.; 10: 59-66.
44. Beccavin C, Malpaux B, Tillet Y. Effect of oestradiol and photoperiod on TH mRNA concentrations in. A 1998; 15: and A12 dopamine cell groups in the ewe. J Neuroendocrinol.; 10: 59-66.
45. Kalra SP, Crowley WR. Norepinephrine-like effects of neuropeptide Y on LH release in the rat. Life Sci 1984; 35: 1173-1176.
46. Clarke IJ, Jessop D, Millar R, Morris M, Bloom S, Lightman S, Coen C, Lew R, Smith I. Many peptides present in the external zone of the median eminence are not released into the hypophysial portal vessels in sheep. Neuroendocrinology 1993; 57: 765-775.
47. Advis JP, Conover CD, McDonald JK, Kuljis RO. Neuropeptide Y regulation of LHRH release in ewe median eminence: immunocytochemistry, tissue content and in vivo analysis. Ann NY Acad Sci 1990; 611: 468-470.
48. Liu J-P, Clarke IJ, Funder JW, Engler D. Studies of the secretion of corticotropin-releasing factor and arginine vasopressin into the hypophysial-portal circulation of the conscious sheep. II. The central noradrenergic and neuropeptide Y pathways cause immediate and prolonged hypothalamic-pituitary-adrenal activation. Potential involvement in the Pseudo-Cushing's syndrome of endogenous depression and anorexia nervosa. J Clin Invest 1994; 93: 1439-1450.
49. Miner JL. Recent advances in the control control of intake in ruminants. J Anim Sci 1992; 70: 1283-1289.
50. Clark JT, Kalra PS, Kalra SP. Neuropeptide Y stimulates feeding and inhibits sexual behaviour in rats. Endocrinology 1985; 117: 2435-2442.
51. Lincoln GA, Richardson M. Photo-neuroendocrine control of seasonal cycles in body weight, pelage growth and reproduction: lessons from the HPD sheep model. Comp Biochem Physiol C 1998; 119: 238-294.
52. Forbes JM. Effects of lighting pattern on growth, lactation and food intake of sheep, cattle and deer. Livestock Production Sci 1982; 9: 361-374.