Facial nerve injury-induced disinhibition in the primary motor cortices of both hemispheres

European Journal of Neuroscience

Volumn 12, Issue 6, 2000, Pages 2190-2194

  Farkas, Tamás ^a,b   Perge, János ^a   Kis, Zsolt ^a   Wolff, Joachim R ^b   Toldi, József ^a,b  

^a UNIVERSITY OF SZEGED   (Hungary)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

Deefferentation; Denervation; Disinhibition; Facial nerve; Inhibition; Motor cortex; N. VII; Nerve injury

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DEAFFERENTATION; ELECTROSTIMULATION; EVOKED RESPONSE; FACIAL NERVE; FACILITATION; FEMALE; HEMISPHERE; MALE; MOTOR CORTEX; NERVE CONDUCTION; NERVE INJURY; NONHUMAN; PRIORITY JOURNAL; SENSORY CORTEX; SKIN INJURY; TRIGEMINAL NERVE;

ANIMALS; DENERVATION; ELECTRIC STIMULATION; EVOKED POTENTIALS, SOMATOSENSORY; EXCITATORY POSTSYNAPTIC POTENTIALS; FACIAL NERVE INJURIES; FEMALE; FUNCTIONAL LATERALITY; MALE; MOTOR CORTEX; NEURAL INHIBITION; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0034039365     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1460-9568.2000.00096.x     Document Type: Article

References (13)

1. Alloway, K.D. & Burton, H. (1991) Differential effects of GABA and bicuculline on rapidly-and slowly-adapting neurons in primary somatosensory cortex of primates. Exp. Brain Res., 85, 598-610.
2. Buchkremer-Ratzmann, I. & Witte, O.W. (1997) Extended brain disinhibition following small photothrombotic lesions in rat frontal cortex. Neuroreport, 8, 519-522.
3. Calford, M.B. & Tweedale, R. (1991) C-fibres provide a source of masking inhibition to primary somatosensory cortex. Proc. R. Soc. Lond. B. Biol. Sci., 243, 269-275.
4. Donoghue, J.P., Suner, S. & Sanes, J.N. (1990) Dynamic organization of primary motor cortex output to target muscles in adult rats. II. Rapid reorganization following motor nerve lesions. Exp. Brain Res., 79, 492-503.
5. Farkas, T., Kis, Z., Toldi, J. & Wolff, J.-R. (1999) Activation of the primary motor cortex by somatosensory stimulation in adult rats is mediated mainly by associational connections from the somatosensory cortex. Neuroscience, 90, 353-361.
6. Garraghty, P.E., Lachica, E.A. & Kaas, J.H. (1991) Injury-induced reorganization of somatosensory cortex is accompanied by reductions in GABA staining. Somatosens. Mot. Res., 8, 347-354.
7. Grimm, U. (1999) Akkumulation von Chloridionen in Neuronen des zentralen Nervensystems adulter Ratten. Doctoral Dissertation, Göttingen University, Göttingen, Germany.
8. Laskawi, R., Rohlmann, A., Landgrebe, M. & Wolff, J.-R. (1997) Rapid astroglial reactions in the motor cortex of adult rats following peripheral facial nerve lesions. Eur. Arch. Otorhinolaryngol., 254, 81-85.
9. McDonald, C.T & Burkhalter, A. (1993) Organization of long-range inhibitory connections with rat visual cortex. J. Neurosci., 13, 768-781.
10. Merrill, E.G. & Wall, P.D. (1972) Factors forming the edge of a receptive field: The presence of relatively ineffective afferent terminals. J. Physiol. (Lond.), 226, 825-846.
11. Staley, K.J., Soldo, B.L. & Proctor, W.R. (1995) Ionic mechanisms of neuronal excitation by inhibitory GABAA receptors. Science, 269, 977-981.
12. Toldi, J., Farkas, T., Perge, J. & Wolff, J.-R. (1999) Facial nerve injury produces a latent somatosensory input through recruitement of the motor cortex in the rat. Neuroreport, 10, 2143-2147.
13. Toldi, J., Laskawi, R., Landgrebe, M. & Wolff, J.-R. (1996) Biphasic reorganisation of somatotopy in the primary motor cortex follows facial nerve lesions in adult rats. Neurosci. Lett., 203, 179-182.