Assessing safety, health, and environmental impact early during process development

Industrial and Engineering Chemistry Research

Volumn 39, Issue 4, 2000, Pages 960-972

  Koller, Guntram ^a   Fischer, Ulrich ^a   Hungerbühler, Konrad ^a  

^a ETH ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ACCIDENT PREVENTION; CHEMICAL OPERATIONS; DRUG PRODUCTS; ENVIRONMENTAL IMPACT; HEALTH HAZARDS; INDUSTRIAL APPLICATIONS; RISK ASSESSMENT; RISK MANAGEMENT;

ENVIRONMENTAL ASSESSMENT; PHARMACEUTICAL INDUSTRY; RISK ANALYSIS;

PROCESS ENGINEERING;

ARTICLE; AUTOMATION; DATA BASE; DRUG INDUSTRY; ENVIRONMENTAL IMPACT ASSESSMENT; EXPLOSION; FIRE; HEALTH HAZARD; RELIABILITY; RISK ASSESSMENT; SAFETY; TOXICITY;

EID: 0034039203     PISSN: 08885885     EISSN: None     Source Type: Journal    
DOI: 10.1021/ie990669i     Document Type: Article

References (30)

1. Khan, F. I.; Abbasi, S. A. Techniques and Methodologies for Risk Analysis in Chemical Process Industry. J. Loss Prev. Process Ind. 1998, 11, 261.
2. Dow Chemicals. Dow's Fire & Explosion Index Hazard Classification Guide. AIChE Technical Manual; American Institute of Chemical Engineers: New York, 1994.
3. Ruppert, K. A. Vereinfachte Risikobewertung. Chem. Ing Tech. 1999, 71, 30.
4. Khan, F. I.; Abbasi, S. A. Inherently Safer Design Based on Rapid Risk Analysis. J. Loss Prev. Process Ind. 1998, 11, 361.
5. Kletz, T. Plant Design for Safety: a User-friendly Approach; Hemisphere Publishing: New York, 1991.
6. Edwards, D. W.; Lawrence, D. Assessing the Inherent Safety of Chemical Process Routes: Is There a Relation between Plant Costs and Inherent Safety. Trans. IChemE 1993, 71B, 252.
7. Cave, S. R.; Edwards, D. W. Chemical Process Route Selection Based On Assessment of Inherent Environmental Hazard. Comput. Chem. Eng. 1997, 21, S965.
8. Heikkilä, A. M.; Hurme, M.; Järveläinen, M. Safety Considerations in Process Synthesis. Comput. Chem. Eng. 1996, 20, S115.
9. Sarigiannis, D. A. Computer-Aided Design for Environment in the Process Industries. Comput. Chem. Eng. 1996, 20, S1407.
10. Pistikopoulos, E. N.; Stefanis, S. K.; Livingston, A. G. A Methodology for Minimum Environmental Impact Analysis. AIChE Symp. Ser. 1994, 90, 139.
11. Heinzle, E.; Weirich, D.; Brogli, F.; Hoffmann, V. H.; Koller, G.; Verduyn, M. A.; Hungerbühler, K. Ecological and Economic Objective Functions for Screening in Integrated Development of Fine Chemical Processes: 1. Flexible and Expandable Framework using Indices. Ind. Eng. Chem. Res. 1998, 37, 3395.
12. Pratt, G.; Gerbec, P. E.; Livingston, S. K.; Oliaei, F.; Bollweg, G. L.; Paterson, S.; Mackay, D. An Indexing System for Comparing Toxic Air Pollutants based upon their Potential Environmental Impacts. Chemosphere 1993, 27, 1359
13. Hansen, B. G.; Haelst, A. G. v.; Leeuwen, K. v.; Zandt, P. v. d. Priority Setting for Existing Chemicals: European Union Risk Ranking Method. Environ. Toxicol. Chem. 1999, 18, 772.
14. Jia, C. Q.; Guardo, A. d.; Mackay, D. Toxic Release Inventories: Opportunities for Improved Presentation and Interpretation. Environ. Sci. Technol. 1996, 30, 86.
15. Mallick, S. K.; Cabezas, H.; Bare, J. C.; Sikdar, S. K. A Pollution Reduction Methodology for Chemical Process Simulators. Ind. Eng. Chem. Res. 1996, 35, 4128.
16. Swedish National Chemicals Inspectorate. Selecting Multiproblem Chemicals for Risk Reduction - Sunset Project - KEMI Report; The Swedish National Chemicals Inspectorate: Stockholm 1995.
17. Sheng, P.; Hertwich, E. Indices for Comparative Waste Assessment in Environmentally-Conscious Manufacturing J Manuf. Sci. Eng. 120, 129-140.
18. Preston, M. L.; Hawksley, J. L. Inherent SHE - 20 years of evolution. IChemE Symp. Ser. 1997, 141, 11.
19. Hendershot, D. C. Measuring Inherent Safety, Health and Environmental Characteristics Early in Process Development. Process Safety Prog. 1997, 16, 78.
20. Debeil, A.; Myrén, L. Outline of an Integrated Approach to Solve Growing Safety and Environmental Conflicts IChemE Loss Prev. Bull. 1994, 119, 18.
21. Turney, R. D.; Mansfield, D. P.; Malmen, Y.; Rogers, R. L.; Verwoered, M.; Soukas, E.; Plaisier, A. The INSIDE Project on Inherent SHE in Process Development and Design - The Toolkit and its Application. IChemE Symp. Ser. 1997, 141, 202.
22. Elliott, A. D.; Sowerby, B.; Crittenden, B. T. Quantitative Environmental Impact Analysis for Clean Design. Comput. Chem Eng. 1996, 20, S1377.
23. Koller, G.; Fischer, U.; Hungerbühler, K. Assessment of Environment-, Health, and Safety Aspects of Fine Chemical Processes during early Design Phases. Comput. Chem. Eng 1999 23, S63.
24. Blickenstorfer, C.; Fischer, U.; Hungerbühler, K. Modeling Energy Consumption in a Multi-Product Batch Plant. 2nd Conference on Process Integration, Modeling and Optimization for Energy Saving and Pollution Reduction (PRES'99); Hungarian Chemical Society: Budapest, 1999; p 175.
25. Chapman, P. M.; Caldwell, R. S.; Chapman, P. F. A Warning: NOECs are Inappropriate for Regulatory Use. Environ Toxicol. Chem. 1996, 15, 77.
26. Baenziger, M.; Mak, C. P.; Mühle, H.; Nobs, F.; Prikos-zovich, W.; Reber, J. L.; Sunay, U. Practical Synthesis of 8a-Amino-2,6-dimethylergoline: An Industrial Perspective. Org Proc Res Dev. 1997, 1, 395.
27. European Chemicals Bureau. Environmental Chemicals Data and Information Network (ECDIN). European Commission, Joint Research Centre: Ispra, 1993.
28. Nationale Alarmzentrale. Informationssystem für gefährliche und umweltrelevante Stoffe (IGS-Datenbank); Zürich, 1997.
29. US Coastal Guard. Chemical Hazard Response Information System (CHRIS); Chemical Information Systems Inc.: Baltimore 1986.
30. Syracuse Research Corporation. Estimation Software; Syracuse, NY, 1998; http://esc.syrres.com/~esc1/estsoft.htm.