1,3,5-Trialkyl-2,4,6-triiodobenzenes: Novel x-ray contrast agents for gastrointestinal imaging

Journal of Medicinal Chemistry

Volumn 43, Issue 10, 2000, Pages 1940-1948

  Estep, Kimberly G ^a,b   Josef, Kurt A ^a   Bacon, Edward R ^a   Illig, Carl R ^a   Toner, John L ^a   Mishra, Dinesh ^a   Blazak, William F ^a   Miller, Dennis M ^a   Johnson, David K ^a   Allen, Jack M ^a   Spencer, Andy ^a   Wilson, Susan A ^a  

^a Nycomed Amersham Imaging   (United States)

^b PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,3,5 TRI N HEXYL 2,4,6 TRIIODOBENZENE; 1,3,5 TRIALKYL 2,4,6 TRIIODOBENZENE; BARIUM SULFATE; BENZENE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CONTRAST RADIOGRAPHY; DIAGNOSTIC IMAGING; DRUG EFFICACY; DRUG SAFETY; DRUG STABILITY; GASTROINTESTINAL RADIOGRAPHY; GASTROINTESTINAL TRACT; LIVER MICROSOME; RECEPTOR AFFINITY;

ABSORPTION; ANIMALS; CHEMISTRY, PHYSICAL; CONTRAST MEDIA; CRICETINAE; DIGESTIVE SYSTEM; DOGS; DRUG DESIGN; EMULSIONS; HUMANS; IODOBENZENES; KINETICS; MALE; MESOCRICETUS; MICE; MICE, INBRED ICR; MICROSOMES, LIVER; MOLECULAR STRUCTURE; RATS; RATS, SPRAGUE-DAWLEY; THYROID DISEASES;

EID: 0034037480     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm990407i     Document Type: Article

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31. Cyclohexane was used as the recrystallization solvent for 13 (see Table 1).